Jose M Lizcano

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. ncbi The insulin signalling pathway
    Jose M Lizcano
    MRC Protein Phosphorylation Unit, School of Life Sciences, MSI/WTB Complex, University of Dundee, DD1 5EH, Dundee, UK
    Curr Biol 12:R236-8. 2002
  2. ncbi Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo
    Jose M Lizcano
    Medical Research Council Protein Phosphorylation Unit, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, United Kingdom
    J Biol Chem 277:27839-49. 2002
  3. ncbi Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B
    Jose M Lizcano
    MRC Protein Phosphorylation Unit, MSI WTB complex, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK
    Biochem J 374:297-306. 2003
  4. ncbi Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate
    Mahaboobi Jaleel
    MRC Protein Phosphorylation Unit, MSI WTB complex, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK
    FEBS Lett 579:1417-23. 2005
  5. ncbi LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
    Jose M Lizcano
    MRC Protein Phosphorylation Unit, School of Life Sciences, University of Dundee, Dundee, UK
    EMBO J 23:833-43. 2004
  6. ncbi High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site
    Ricardo M Biondi
    Division of Signal Transduction Therapy, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK
    EMBO J 21:4219-28. 2002
  7. ncbi High-content peptide microarrays for deciphering kinase specificity and biology
    Mike Schutkowski
    Jerini AG, Berlin, Germany
    Angew Chem Int Ed Engl 43:2671-4. 2004

Detail Information

Publications7

  1. ncbi The insulin signalling pathway
    Jose M Lizcano
    MRC Protein Phosphorylation Unit, School of Life Sciences, MSI/WTB Complex, University of Dundee, DD1 5EH, Dundee, UK
    Curr Biol 12:R236-8. 2002
  2. ncbi Molecular basis for the substrate specificity of NIMA-related kinase-6 (NEK6). Evidence that NEK6 does not phosphorylate the hydrophobic motif of ribosomal S6 protein kinase and serum- and glucocorticoid-induced protein kinase in vivo
    Jose M Lizcano
    Medical Research Council Protein Phosphorylation Unit, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, United Kingdom
    J Biol Chem 277:27839-49. 2002
    ....
  3. ncbi Insulin-induced Drosophila S6 kinase activation requires phosphoinositide 3-kinase and protein kinase B
    Jose M Lizcano
    MRC Protein Phosphorylation Unit, MSI WTB complex, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK
    Biochem J 374:297-306. 2003
    ..The results of the present study support the view that, in Drosophila cells, dPI3K and dPKB, as well dTOR, are required for the activation of dS6K by insulin...
  4. ncbi Identification of the sucrose non-fermenting related kinase SNRK, as a novel LKB1 substrate
    Mahaboobi Jaleel
    MRC Protein Phosphorylation Unit, MSI WTB complex, University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, UK
    FEBS Lett 579:1417-23. 2005
    ..These results provide evidence that SNRK could mediate some of the physiological effects of LKB1...
  5. ncbi LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
    Jose M Lizcano
    MRC Protein Phosphorylation Unit, School of Life Sciences, University of Dundee, Dundee, UK
    EMBO J 23:833-43. 2004
    ..Between them, these kinases may mediate the physiological effects of LKB1, including its tumour suppressor function...
  6. ncbi High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site
    Ricardo M Biondi
    Division of Signal Transduction Therapy, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK
    EMBO J 21:4219-28. 2002
    ..We discuss the possibility that an analogous phosphate-binding regulatory motif may participate in the activation of other AGC kinases. Furthermore, the structure of PDK1 provides a scaffold for the design of specific PDK1 inhibitors...
  7. ncbi High-content peptide microarrays for deciphering kinase specificity and biology
    Mike Schutkowski
    Jerini AG, Berlin, Germany
    Angew Chem Int Ed Engl 43:2671-4. 2004