P Little

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. pmc Delayed prescribing of antibiotics for upper respiratory tract infection
    Paul Little
    BMJ 331:301-2. 2005
  2. pmc Delayed antibiotic prescribing strategies for respiratory tract infections in primary care: pragmatic, factorial, randomised controlled trial
    Paul Little
    University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST, UK
    BMJ 348:g1606. 2014
  3. pmc Predictors of suppurative complications for acute sore throat in primary care: prospective clinical cohort study
    Paul Little
    Primary Care and Population Sciences Division, University of Southampton, UK
    BMJ 347:f6867. 2013
  4. pmc Clinical score and rapid antigen detection test to guide antibiotic use for sore throats: randomised controlled trial of PRISM (primary care streptococcal management)
    Paul Little
    University of Southampton Medical School, Aldermoore Health Centre, Southampton SO16 5ST, UK
    BMJ 347:f5806. 2013
  5. pmc Ibuprofen, paracetamol, and steam for patients with respiratory tract infections in primary care: pragmatic randomised factorial trial
    Paul Little
    University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST, UK
    BMJ 347:f6041. 2013
  6. ncbi request reprint Antibiotic prescription strategies for acute sore throat: a prospective observational cohort study
    Paul Little
    Primary Care and Population Sciences Division, University of Southampton, Southampton, UK Electronic address
    Lancet Infect Dis 14:213-9. 2014
  7. pmc Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial
    Paul Little
    Primary Care and Population Sciences Division, University of Southampton, Southampton, UK
    Lancet 382:1175-82. 2013
  8. pmc The diagnosis of urinary tract infections in young children (DUTY): protocol for a diagnostic and prospective observational study to derive and validate a clinical algorithm for the diagnosis of UTI in children presenting to primary care with an acute ill
    Harriet Downing
    Academic Unit of Primary Health Care, School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Clifton, Bristol BS8 2PS, UK
    BMC Infect Dis 12:158. 2012
  9. pmc Rationale, design and organization of the delayed antibiotic prescription (DAP) trial: a randomized controlled trial of the efficacy and safety of delayed antibiotic prescribing strategies in the non-complicated acute respiratory tract infections in gener
    Mariam de la Poza Abad
    Centro de AtenciĆ³n Primaria Doctor Carles Ribas, Barcelona, Spain
    BMC Fam Pract 14:63. 2013
  10. pmc General practitioners' views on the acceptability and applicability of a web-based intervention to reduce antibiotic prescribing for acute cough in multiple European countries: a qualitative study prior to a randomised trial
    Sibyl Anthierens
    Centre for General Practice, Vaccine and Infectious Disease Institute VAXINFECTIO, Laboratory of Microbiology, University of Antwerp, Antwerp, Belgium
    BMC Fam Pract 13:101. 2012

Collaborators

Detail Information

Publications99

  1. pmc Delayed prescribing of antibiotics for upper respiratory tract infection
    Paul Little
    BMJ 331:301-2. 2005
  2. pmc Delayed antibiotic prescribing strategies for respiratory tract infections in primary care: pragmatic, factorial, randomised controlled trial
    Paul Little
    University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST, UK
    BMJ 348:g1606. 2014
    ..To estimate the effectiveness of different strategies involving delayed antibiotic prescription for acute respiratory tract infections...
  3. pmc Predictors of suppurative complications for acute sore throat in primary care: prospective clinical cohort study
    Paul Little
    Primary Care and Population Sciences Division, University of Southampton, UK
    BMJ 347:f6867. 2013
    ..To document whether elements of a structured history and examination predict adverse outcome of acute sore throat...
  4. pmc Clinical score and rapid antigen detection test to guide antibiotic use for sore throats: randomised controlled trial of PRISM (primary care streptococcal management)
    Paul Little
    University of Southampton Medical School, Aldermoore Health Centre, Southampton SO16 5ST, UK
    BMJ 347:f5806. 2013
    ..To determine the effect of clinical scores that predict streptococcal infection or rapid streptococcal antigen detection tests compared with delayed antibiotic prescribing...
  5. pmc Ibuprofen, paracetamol, and steam for patients with respiratory tract infections in primary care: pragmatic randomised factorial trial
    Paul Little
    University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST, UK
    BMJ 347:f6041. 2013
    ..To assess strategies for advice on analgesia and steam inhalation for respiratory tract infections...
  6. ncbi request reprint Antibiotic prescription strategies for acute sore throat: a prospective observational cohort study
    Paul Little
    Primary Care and Population Sciences Division, University of Southampton, Southampton, UK Electronic address
    Lancet Infect Dis 14:213-9. 2014
    ..Observational evidence is important in view of poor compliance with antibiotic treatment outside trials, but no prospective observational cohort studies have been done to date...
  7. pmc Effects of internet-based training on antibiotic prescribing rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial
    Paul Little
    Primary Care and Population Sciences Division, University of Southampton, Southampton, UK
    Lancet 382:1175-82. 2013
    ..Education of physicians and patients can lower prescribing levels, but it frequently relies on highly trained staff. We assessed whether internet-based training methods could alter prescribing practices in multiple health-care systems...
  8. pmc The diagnosis of urinary tract infections in young children (DUTY): protocol for a diagnostic and prospective observational study to derive and validate a clinical algorithm for the diagnosis of UTI in children presenting to primary care with an acute ill
    Harriet Downing
    Academic Unit of Primary Health Care, School of Social and Community Medicine, University of Bristol, Canynge Hall, 39 Whatley Road, Clifton, Bristol BS8 2PS, UK
    BMC Infect Dis 12:158. 2012
    ..The overall study aim is to derive and validate a cost-effective clinical algorithm for the diagnosis of UTI in children presenting to primary care acutely unwell...
  9. pmc Rationale, design and organization of the delayed antibiotic prescription (DAP) trial: a randomized controlled trial of the efficacy and safety of delayed antibiotic prescribing strategies in the non-complicated acute respiratory tract infections in gener
    Mariam de la Poza Abad
    Centro de AtenciĆ³n Primaria Doctor Carles Ribas, Barcelona, Spain
    BMC Fam Pract 14:63. 2013
    ..This together with the alarming increase of bacterial resistance due to increased use of antimicrobials calls for a need to consider strategies to reduce their use. One of these strategies is the delayed prescription of antibiotics...
  10. pmc General practitioners' views on the acceptability and applicability of a web-based intervention to reduce antibiotic prescribing for acute cough in multiple European countries: a qualitative study prior to a randomised trial
    Sibyl Anthierens
    Centre for General Practice, Vaccine and Infectious Disease Institute VAXINFECTIO, Laboratory of Microbiology, University of Antwerp, Antwerp, Belgium
    BMC Fam Pract 13:101. 2012
    ..We explored GPs' views on the initial version of INTRO to test acceptability and potentially increase applicability for use in multiple countries before the start of a randomised trial...
  11. pmc Targets and self-management for the control of blood pressure in stroke and at risk groups (TASMIN-SR): protocol for a randomised controlled trial
    Claire O'Brien
    Primary Care Clinical Sciences, NIHR School for Primary Care Research, University of Birmingham, Edgbaston, Birmingham, UK
    BMC Cardiovasc Disord 13:21. 2013
    ..This trial therefore aims to assess the added value of self-management in high risk groups over and above usual care...
  12. pmc Incidence and clinical variables associated with streptococcal throat infections: a prospective diagnostic cohort study
    Paul Little
    Primary Care and Population Science, Faculty of Medicine University of Southampton, UK
    Br J Gen Pract 62:e787-94. 2012
    ..Non-group A strains share major virulence factors with group A, but it is unclear how commonly they present and whether their presentation differs...
  13. doi request reprint Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspected: a 12-country, randomised, placebo-controlled trial
    Paul Little
    Primary Care and Population Sciences Division, University of Southampton, Southampton, UK
    Lancet Infect Dis 13:123-9. 2013
    ..We aimed to compare the benefits and harms of amoxicillin for acute lower-respiratory-tract infection with those of placebo both overall and in patients aged 60 years or older...
  14. pmc Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study)
    Martin C Gulliford
    Primary Care and Public Health Sciences, King s College London, UK
    Trials 12:115. 2011
    ..The protocol describes one application: a study of antibiotic prescribing for acute respiratory infection; a second protocol outlines an intervention in a less frequent chronic condition of public health importance, stroke...
  15. pmc Design, analysis and presentation of factorial randomised controlled trials
    Alan A Montgomery
    Division of Primary Health Care, University of Bristol, Cotham House, Cotham Hill, Bristol BS6 6JL, UK
    BMC Med Res Methodol 3:26. 2003
    ..Factorial trials require special considerations, however, particularly at the design and analysis stages...
  16. pmc Understanding reactions to an internet-delivered health-care intervention: accommodating user preferences for information provision
    Lucy Yardley
    School of Psychology, University of Southampton, Southampton, UK
    BMC Med Inform Decis Mak 10:52. 2010
    ....
  17. pmc Management of irritable bowel syndrome in primary care: feasibility randomised controlled trial of mebeverine, methylcellulose, placebo and a patient self-management cognitive behavioural therapy website. (MIBS trial)
    Hazel A Everitt
    Primary Medical Care, School of Medicine, University of Southampton, Southampton SO17 1BJ, UK
    BMC Gastroenterol 10:136. 2010
    ..We have developed a web-based CBT self-management programme, Regul8, based on an existing evidence based self-management manual and in partnership with patients. This could increase access with minimal increased costs...
  18. pmc Building an international network for a primary care research program: reflections on challenges and solutions in the set-up and delivery of a prospective observational study of acute cough in 13 European countries
    Jacqueline Nuttall
    South East Wales Trials Unit SEWTU, Department of Primary Care and Public Health, School of Medicine, Cardiff University, Neuadd Meirionnydd, UK
    BMC Fam Pract 12:78. 2011
    ....
  19. pmc Developing a computer delivered, theory based intervention for guideline implementation in general practice
    Lisa McDermott
    School of Psychology, University of Southampton, Shakleton Building, Highfield, Southampton, UK
    BMC Fam Pract 11:90. 2010
    ..Specifically, our aim was to develop computer-delivered prompts to promote guideline adherence for antibiotic prescribing in respiratory tract infections (RTIs), and adherence to recommendations for secondary stroke prevention...
  20. ncbi request reprint Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: a randomized controlled trial
    Paul Little
    Primary Medical Care Group, University of Southampton, Highfield, England
    JAMA 293:3029-35. 2005
    ..Acute lower respiratory tract infection is the most common condition treated in primary care. Many physicians still prescribe antibiotics; however, systematic reviews of the use of antibiotics are small and have diverse conclusions...
  21. pmc Validating the prediction of lower urinary tract infection in primary care: sensitivity and specificity of urinary dipsticks and clinical scores in women
    Paul Little
    Community Clinical Sciences Division, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton
    Br J Gen Pract 60:495-500. 2010
    ..Dipsticks are one of the most commonly used near-patient tests in primary care, but few clinical or dipstick algorithms have been rigorously developed...
  22. pmc A randomised controlled trial of three pragmatic approaches to initiate increased physical activity in sedentary patients with risk factors for cardiovascular disease
    Paul Little
    Primary Medical Care, University of Southampton, Aldermoor Health Centre Practice, Southampton
    Br J Gen Pract 54:189-95. 2004
    ..Physical activity is a major modifiable risk factor for cardiovascular disease, but it is unclear what combination of feasible approaches, using existing resources in primary care, work best to initiate increased physical activity...
  23. pmc Effectiveness of five different approaches in management of urinary tract infection: randomised controlled trial
    P Little
    Primary Care Medical Group, Community Clinical Sciences Division, University of Southampton School of Medicine, Southampton SO16 5ST
    BMJ 340:c199. 2010
    ..To assess the impact of different management strategies in urinary tract infections...
  24. pmc Presentation, pattern, and natural course of severe symptoms, and role of antibiotics and antibiotic resistance among patients presenting with suspected uncomplicated urinary tract infection in primary care: observational study
    P Little
    Primary Care Medical Group, Community Clinical Sciences Division CCS, School of Medicine, University of Southampton, Aldermoor Health Centre, Southampton SO16 6ST
    BMJ 340:b5633. 2010
    ..To assess the natural course and the important predictors of severe symptoms in urinary tract infection and the effect of antibiotics and antibiotic resistance...
  25. pmc Longer term outcomes from a randomised trial of prescribing strategies in otitis media
    Paul Little
    Community Clinical Sciences Primary Medical Care Group, University of Southampton, Aldermoor Health Centre, Southampton
    Br J Gen Pract 56:176-82. 2006
    ..There are limited data about the longer-term outcomes in acute otitis media (AOM) when comparing the realistic alternatives of immediate prescription of antibiotics and a 'wait and see' or delayed prescribing policy...
  26. ncbi request reprint Where next with antibiotics and respiratory tract infections?
    Paul Little
    Primary Medical Care Group, Southampton University, Aldermoor Health Centre, Aldermoor Close, Southampton S016 5ST, England
    J Fam Pract 51:337-8. 2002
  27. pmc Developing clinical rules to predict urinary tract infection in primary care settings: sensitivity and specificity of near patient tests (dipsticks) and clinical scores
    Paul Little
    Community Clinical Sciences Division, Southampton University, UK
    Br J Gen Pract 56:606-12. 2006
    ..Systematic reviews have not documented any adequately powered studies in primary care that assess independent predictors of laboratory diagnosis...
  28. doi request reprint Dipsticks and diagnostic algorithms in urinary tract infection: development and validation, randomised trial, economic analysis, observational cohort and qualitative study
    P Little
    Community Clinical Sciences Division, University of Southampton, UK
    Health Technol Assess 13:iii-iv, ix-xi, 1-73. 2009
    ....
  29. pmc Preferences of patients for patient centred approach to consultation in primary care: observational study
    P Little
    Primary Medical Care Group, Community Clinical Sciences Division, University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST, UK
    BMJ 322:468-72. 2001
    ..Doctors should be sensitive to patients who have a strong preference for patient centredness-those vulnerable either psychosocially or because they are feeling unwell...
  30. pmc Psychosocial, lifestyle, and health status variables in predicting high attendance among adults
    P Little
    Primary Medical Care Group, Aldemoor Health Centre, Southampton
    Br J Gen Pract 51:987-94. 2001
    ..Most quantitative studies have concentrated on very high attenders--not those attending five or more times a year, who are responsible for most (60%) consultations--and have assessed neither the role of lifestyle nor patients' attitudes...
  31. pmc Randomised controlled trial of self management leaflets and booklets for minor illness provided by post
    P Little
    Primary Medical Care Group, Aldermoor Health Centre, Southampton SO16 5ST
    BMJ 322:1214-6, 1217. 2001
    ..To assess the effectiveness of providing information by post about managing minor illnesses. Design: Randomised controlled trial...
  32. pmc Women's views about management and cause of urinary tract infection: qualitative interview study
    G M Leydon
    Primary Medical Care, Community Clinical Sciences Division, University of Southampton School of Medicine, Aldermoor Health Centre, Southampton SO16 5ST
    BMJ 340:c279. 2010
    ..To explore the views of women with urinary tract infection on the acceptability of different strategies for managing the infection, including delayed use of antibiotics, and the cause of infection...
  33. pmc Pragmatic randomised controlled trial of two prescribing strategies for childhood acute otitis media
    P Little
    Community Clinical Sciences Primary Medical Care Group, University of Southampton, Aldermoor Health Centre, Southampton SO15 6ST
    BMJ 322:336-42. 2001
    ..To compare immediate with delayed prescribing of antibiotics for acute otitis media...
  34. doi request reprint Are smokers with acute cough in primary care prescribed antibiotics more often, and to what benefit? An observational study in 13 European countries
    N Stanton
    Dept of Primary Care and Public Health, School of Medicine, Cardiff University, Neuadd Meirionnydd, Heath Park, Cardiff, UK
    Eur Respir J 35:761-7. 2010
    ..Smoking status was used as an independent factor to determine whether or not to prescribe an antibiotic. Being prescribed an antibiotic was not associated with recovery in smokers...
  35. doi request reprint Antibiotic prescribing for discoloured sputum in acute cough/lower respiratory tract infection
    C C Butler
    Dept of Primary Care and Public Health, School of Medicine, Cardiff University, Cardiff, UK
    Eur Respir J 38:119-25. 2011
    ..Sputum colour, alone or together with feeling generally unwell, was not associated with recovery or benefit from antibiotic treatment...
  36. ncbi request reprint Impact of the introduction of fee for service payments on types of minor surgical procedures undertaken by general practitioners: observational study
    Pete Pockney
    University Surgery, University of Southampton, F Level, Centre Block, Southampton General Hospital, Southampton SO16 6YD, UK
    J Public Health (Oxf) 26:264-7. 2004
    ....
  37. ncbi request reprint Acute sinusitis: which factors do FPs believe are most diagnostic and best predict antibiotic efficacy?
    I Williamson
    Department of Primary Medical Care, University of Southampton, Aldermoor Close, Southampton SO16 5ST, Hants, UK
    J Fam Pract 55:789-96. 2006
  38. pmc Observational study of effect of patient centredness and positive approach on outcomes of general practice consultations
    P Little
    Primary Medical Care Group, Community Clinical Sciences Division, Faculty of Medicine, Southhampton University, Southampton SO165ST
    BMJ 323:908-11. 2001
    ..To measure patients' perceptions of patient centredness and the relation of these perceptions to outcomes...
  39. ncbi request reprint Validation study of a diary for use in acute lower respiratory tract infection
    L Watson
    University of Southampton, Southampton, UK
    Fam Pract 18:553-4. 2001
    ..This instrument could be used as a routine measure of LRTi in further research in both primary and secondary care...
  40. pmc Family influences in a cross-sectional survey of higher child attendance
    P Little
    Primary Medical Care Group, Aldemoor Health Centre, Southampton
    Br J Gen Pract 51:977-81, 984. 2001
    ..A quarter of all consultations are for children, but there is little quantitative evidence documenting what parental factors are important in the decision to consult...
  41. doi request reprint A double-blind randomised placebo-controlled trial of topical intranasal corticosteroids in 4- to 11-year-old children with persistent bilateral otitis media with effusion in primary care
    I Williamson
    Primary Medical Care, University of Southampton, Aldermoor Health Centre, Southampton, UK
    Health Technol Assess 13:1-144. 2009
    ..To determine the clinical effectiveness and cost-effectiveness of topical mometasone in children with bilateral otitis media with effusion (OME)...
  42. ncbi request reprint A prospective randomised comparison of minor surgery in primary and secondary care. The MiSTIC trial
    S George
    Public Health Sciences and Medical Statistics, University of Southampton School of Medicine, UK
    Health Technol Assess 12:iii-iv, ix-38. 2008
    ..To determine whether there is equivalence in the competence of GPs and hospital doctors to perform a range of elective minor surgical procedures, in terms of the safety, quality and cost of care...
  43. pmc Predicting the duration of symptoms in lower respiratory tract infection
    Michael Moore
    University of Southampton, Division of Community Clinical Sciences, Southampton, SO16 5ST
    Br J Gen Pract 58:88-92. 2008
    ..Antibiotic treatment makes little or no difference to the duration of cough. Limited information is currently available regarding predictors of illness duration...
  44. doi request reprint A review of the literature in applied and specialised kinesiology
    Sue Hall
    Complementary Medicine Research Unit, School of Medicine, University of Southampton, UK
    Forsch Komplementmed 15:40-6. 2008
    ..Anecdotal evidence suggests kinesiology is helpful, therefore we wished to critically review the literature...
  45. ncbi request reprint Otitis media with effusion: the long and winding road?
    Ian Williamson
    University of Southampton, Community Clinical Science Division, Medical Faculty, Aldermoor Close, Southampton SO16 5ST, UK
    Arch Dis Child 93:268-9. 2008
  46. pmc The journey from self-care to GP care: a qualitative interview study of women presenting with symptoms of urinary tract infection
    Geraldine M Leydon
    Primary Medical Care, Community Clinical Sciences Division, University of Southampton School of Medicine, Southampton
    Br J Gen Pract 59:e219-25. 2009
    ..Urinary tract infection (UTI) is one of the commonest acute infections presenting to primary care. Little is known of women's experiences of UTI; self-care strategies and key triggers for their consulting behaviour are also little known...
  47. doi request reprint Patients' views of receiving lessons in the Alexander technique and an exercise prescription for managing back pain in the ATEAM trial
    Lucy Yardley
    Centre for Applications of Health Psychology, School of Psychology, University of Southampton, Southampton, UK
    Fam Pract 27:198-204. 2010
    ..Lessons in the Alexander Technique and exercise prescription proved effective for managing low back pain in primary care in a clinical trial...
  48. pmc Effect of antibiotic prescribing strategies and an information leaflet on longer-term reconsultation for acute lower respiratory tract infection
    Michael Moore
    Division of Community Clinical Sciences, University of Southampton, Southampton
    Br J Gen Pract 59:728-34. 2009
    ..Limited evidence suggests that delayed prescribing may influence future consultation behaviour...
  49. pmc Evaluation of a Web-based intervention providing tailored advice for self-management of minor respiratory symptoms: exploratory randomized controlled trial
    Lucy Yardley
    School of Psychology, University of Southampton, Southampton, United Kingdom
    J Med Internet Res 12:e66. 2010
    ....
  50. pmc Cost effectiveness of management strategies for urinary tract infections: results from randomised controlled trial
    David Turner
    Wessex Institute, University of Southampton, Alpha House, Southampton Science Park, Chilworth, Southampton SO16 7NS
    BMJ 340:c346. 2010
    ..To assess the cost effectiveness of different management strategies for urinary tract infections...
  51. pmc Topical intranasal corticosteroids in 4-11 year old children with persistent bilateral otitis media with effusion in primary care: double blind randomised placebo controlled trial
    Ian Williamson
    Primary Medical Care, University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST
    BMJ 339:b4984. 2009
    ..To determine the clinical effectiveness of topical intranasal corticosteroids in children with bilateral otitis media with effusion...
  52. doi request reprint Communication challenges of HPV vaccination
    Elizabeth C F Brown
    Primary Medical Care, Community Clinical Sciences Division, University of Southampton School of Medicine, Aldermoor Health Centre, Southampton SO16 5ST, UK
    Fam Pract 27:224-9. 2010
    ..Previous research has explored public understanding of the causes of cervical cancer and found little awareness of the role of HPV...
  53. ncbi request reprint Antibiotics and topical nasal steroid for treatment of acute maxillary sinusitis: a randomized controlled trial
    Ian G Williamson
    Department of Medicine, University of Southampton, Southampton, England
    JAMA 298:2487-96. 2007
    ..Acute sinusitis is a common clinical problem that usually results in a prescription for antibiotics but the role of antibiotics is debated. Anti-inflammatory drugs such as topical steroids may be beneficial but are underresearched...
  54. pmc Predictors of poor outcome and benefits from antibiotics in children with acute otitis media: pragmatic randomised trial
    Paul Little
    Community Clinical Sciences Primary Medical Care Group, University of Southampton, Aldermoor Health Centre, Southampton SO15 6ST
    BMJ 325:22; discussion 22. 2002
    ..To identify which children with acute otitis media are at risk of poor outcome and to assess benefit from antibiotics in these children...
  55. pmc Randomised controlled trial of Alexander technique lessons, exercise, and massage (ATEAM) for chronic and recurrent back pain
    Paul Little
    Primary Care Group, Community Clinical Sciences Division, University of Southampton, Aldermoor Health Centre, Southampton SO16 5ST
    BMJ 337:a884. 2008
    ....
  56. pmc Penicillin for acute sore throat in children: randomised, double blind trial. Commentary: More valid criteria may be needed
    Paul Little
    University of Southampton, Aldermoor Health Centre, Southampton SO16 55T
    BMJ 327:1327-8. 2003
  57. pmc Watchful waiting is useful for children with recurrent throat infections
    Paul Little
    Primary Medical Care, Community Clinical Sciences Division, Southampton University, Aldermoor Health Centre, Southampton SO16 5ST
    BMJ 329:654. 2004
  58. pmc Advice to parents has limited effect--where next?
    Paul Little
    Southampton University, Aldermoor Health Centre, Southampton SO16 5ST
    BMJ 329:269. 2004
  59. pmc Randomised controlled factorial trial of dietary advice for patients with a single high blood pressure reading in primary care
    Paul Little
    University of Southampton, Division of Community Clinical Sciences, Primary Medical Care Group, Southampton SO16 5ST
    BMJ 328:1054. 2004
    ..To assess the effect of brief interventions during the "watchful waiting" period for hypertension...
  60. pmc Importance of patient pressure and perceived pressure and perceived medical need for investigations, referral, and prescribing in primary care: nested observational study
    Paul Little
    Primary Medical Care, Community Clinical Sciences Division, Southampton University, Aldermoor Health Centre, Southampton SO16 5ST
    BMJ 328:444. 2004
    ..To assess how pressures from patients on doctors in the consultation contribute to referral and investigation...
  61. pmc Randomised controlled trial of effect of leaflets to empower patients in consultations in primary care
    Paul Little
    Primary Medical Care, Community Clinical Sciences Division, Southampton University, Aldermoor Health Centre, Southampton SO16 5ST
    BMJ 328:441. 2004
    ..To assess the impact of leaflets encouraging patients to raise concerns and to discuss symptoms or other health related issues in the consultation...
  62. ncbi request reprint A questionnaire to measure satisfaction with community services for informal carers of stroke patients: construction and initial piloting
    Chantal Simon
    Department of Primary Medical Care, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton, UK
    Health Soc Care Community 11:129-37. 2003
    ..These factors have marked similarities to those found in the field of patient satisfaction with community services...
  63. ncbi request reprint Continuing professional development (CPD): GPs' perceptions of post-graduate education-approved (PGEA) meetings and personal professional development plans (PDPs)
    Paul Little
    Community Clinical Sciences Primary Medical Care Group, University of Southampton, Aldermoor Health Centre, Aldermoor Close, UK
    Fam Pract 20:192-8. 2003
    ..However, there is very little empirical evidence about the usefulness to GPs of different kinds of educational meeting or of PDPs...
  64. pmc A qualitative study of patients' perceptions of acute infective conjunctivitis
    Hazel Everitt
    Aldermoor Health Centre, Aldermoor Close, Southampton SO16 5ST
    Br J Gen Pract 53:36-41. 2003
    ..Patients' understanding of conjunctivitis, their reasons for attendance, and their responses to different management strategies, are unknown...
  65. pmc Why do general practitioners prescribe antibiotics for sore throat? Grounded theory interview study
    Satinder Kumar
    Department of Primary Medical Care, University of Southampton, Southampton SO17 3RT
    BMJ 326:138. 2003
    ..To understand why general practitioners prescribe antibiotics for some cases of sore throat and to explore the factors that influence their prescribing...
  66. ncbi request reprint How do GPs diagnose and manage acute infective conjunctivitis? A GP survey
    Hazel Everitt
    Community Clinical Sciences CCS Division, Faculty of Medicine, Health and Biological Sciences, Southampton University, UK
    Fam Pract 19:658-60. 2002
    ..To determine GPs' diagnosis and management of acute infective conjunctivitis (AIC)-one of the commonest but least researched acute infections seen in primary care...
  67. pmc Comparison of acceptability of and preferences for different methods of measuring blood pressure in primary care
    Paul Little
    Community Clinical Sciences Division Primary Medical Care Group, Faculty of Medicine, Health and Biological Sciences, Southampton University, Aldermoor Health Centre, Southampton SO16 5ST, UK
    BMJ 325:258-9. 2002
  68. ncbi request reprint Feasibility and acceptability of providing nurse counsellor genetics clinics in primary care
    Greta Westwood
    Department of Genetics, Wessex Clinical Genetics Service, Southampton, UK
    J Adv Nurs 53:591-604. 2006
    ....
  69. pmc Consultations for middle ear disease, antibiotic prescribing and risk factors for reattendance: a case-linked cohort study
    Ian Williamson
    Department of Primary Medical Care, Community Clinical Science Division, School of Medicine, University of Southampton, Southampton
    Br J Gen Pract 56:170-5. 2006
    ..Otitis media is the most common reason for children to receive antibiotics, but there is no evidence about the effect of prescribing on reattendance...
  70. pmc Comparison of agreement between different measures of blood pressure in primary care and daytime ambulatory blood pressure
    Paul Little
    Community Clinical Sciences Division Primary Medical Care Group, Faculty of Medicine, Health and Biological Sciences, Southampton University, Aldermoor Health Centre, Southampton SO16 5ST, UK
    BMJ 325:254. 2002
    ..To assess alternatives to measuring ambulatory pressure, which best predicts response to treatment and adverse outcome...
  71. ncbi request reprint Humidified air inhalation for treating croup: a systematic review and meta-analysis
    Michael Moore
    Three Swans Surgery, Rollestone Street, Salisbury SP1 1DX, UK
    Fam Pract 24:295-301. 2007
    ..Croup (laryngotracheobronchitis) is a common cause of upper airway obstruction in children. Treatment with humidified air was previously widely used and is still commonly recommended as home treatment...
  72. pmc Antibiotic prescribing and admissions with major suppurative complications of respiratory tract infections: a data linkage study
    Paul Little
    Community Clinical Sciences Primary Medical Care Group, University of Southampton, Aldermoor Health Centre, Aldermoor Close
    Br J Gen Pract 52:187-90, 193. 2002
    ..Systematic reviews of antibiotic treatment of common acute respiratory tract infections (RTIs) suggest modest symptomatic benefit, but provide limited evidence that prescribing prevents complications...
  73. pmc Use of antibiotics for sore throat and incidence of quinsy
    Nick Dunn
    University of Southampton, Biomedical Sciences Building, Southampton, SO16 7PX
    Br J Gen Pract 57:45-9. 2007
    ..Quinsy is the most common major suppurative complication of sore throat. Evidence on the effectiveness of antibiotics in preventing quinsy is sparse...
  74. ncbi request reprint Interaction between physical activity and diet: implications for blood pressure management in primary care
    B M Margetts
    Institute of Human Nutrition, University of Southampton, Southampton General Hospital, UK
    Public Health Nutr 2:377-82. 1999
    ..This review summarises the evidence for the effectiveness of primary care based interventions of diet and physical activity aimed at reducing blood pressure...
  75. doi request reprint Using mixed methods to design a web-based behavioural intervention to reduce transmission of colds and flu
    L Yardley
    University of Southampton, UK
    J Health Psychol 16:353-64. 2011
    ..The questionnaire results confirmed our assumptions, including hand-washing as the appropriate target behaviour...
  76. ncbi request reprint Should we give detailed advice and information booklets to patients with back pain? A randomized controlled factorial trial of a self-management booklet and doctor advice to take exercise for back pain
    P Little
    Primary Medical Care Group, Community Clinical Sciences, University of Southampton, UK
    Spine (Phila Pa 1976) 26:2065-72. 2001
    ..Randomized controlled factorial trial...
  77. ncbi request reprint The safety and effectiveness of different methods of earwax removal: a systematic review and economic evaluation
    A J Clegg
    Southampton Health Technology Assessments Centre, University of Southampton, UK
    Health Technol Assess 14:1-192. 2010
    ..Current practice for earwax removal generally involves the use of a softening agent, followed by irrigation of the ear if required. However, the safety and benefits of the different methods of removal are not known for certain...
  78. pmc Effect of educational leaflets and questions on knowledge of contraception in women taking the combined contraceptive pill: randomised controlled trial
    P Little
    Primary Medical Care, Faculty of Health Medicine and Biological Sciences, Aldermoor Health Centre, Southampton S016 5ST
    BMJ 316:1948-52. 1998
    ..To assess whether provision of educational leaflets or questions on contraception improves knowledge of contraception in women taking the combined contraceptive pill...
  79. doi request reprint An exploratory pilot study to design and assess the credibility of a sham kinesiology treatment
    Sue Hall
    Complementary Medicine Research Unit, School of Medicine, University of Southampton, United Kingdom
    Forsch Komplementmed 15:321-6. 2008
    ..We report the exploratory 2-stage development and pilot of a sham kinesiology treatment for use in a clinical trial to evaluate the specific effects of this intervention...
  80. ncbi request reprint Professional kinesiology practice for chronic low back pain: single-blind, randomised controlled pilot study
    S Eardley
    Complementary and Integrative Medicine Research, Primary Medical Care, University of Southampton, UK
    Forsch Komplementmed 20:180-8. 2013
    ..WLC's were re-randomised to real or sham after 6 weeks. The main outcome was a change in RMDQ from baseline to end of 5 weeks of real or sham PKP...
  81. ncbi request reprint The association between diet and chronic obstructive pulmonary disease in subjects selected from general practice
    L Watson
    Primary Medical Care Dept, University of Southampton, Aldermoor Health Centre, UK
    Eur Respir J 20:313-8. 2002
    ..In conclusion, fruit and vegetable consumption is inversely associated with chronic obstructive pulmonary disease and may explain why some smokers do not develop chronic obstructive pulmonary disease...
  82. ncbi request reprint Unwanted pregnancy and contraceptive knowledge: identifying vulnerable groups from a randomized controlled trial of educational interventions
    P Little
    Primary Medical Care Group, University of Southampton, Aldermoor Health Centre, Aldermoor Close, Southampton SO16 5ST, UK
    Fam Pract 18:449-53. 2001
    ....
  83. ncbi request reprint Seeking an oracle: using the Delphi process to develop practice guidelines for the treatment of endometriosis with Chinese herbal medicine
    Andrew Flower
    University of Southampton, Southampton, United Kingdom
    J Altern Complement Med 13:969-76. 2007
    ..The Delphi process may offer a pragmatic way to establish good practice guidelines until more rigorous forms of assessment can be undertaken...
  84. ncbi request reprint The back home trial: general practitioner-supported leaflets may change back pain behavior
    Lisa Roberts
    Department of Physiotherapy, Southampton University Hospitals Trust, Highfield, Hants, United Kingdom
    Spine (Phila Pa 1976) 27:1821-8. 2002
    ..A single-blind randomized controlled trial of a leaflet developed for people with acute low back pain was compared with the usual general practitioner management of back pain...
  85. pmc Managing earwax in primary care: efficacy of self-treatment using a bulb syringe
    Richard Coppin
    The Surgery, Overton
    Br J Gen Pract 58:44-9. 2008
    ..Irrigating ears to remove wax is a time-consuming procedure in UK primary care. In many other countries bulb syringes are used for self-clearance of earwax but evidence of their effectiveness is lacking...
  86. pmc X-rays for back pain?
    Paul Little
    Br J Gen Pract 52:534-5. 2002
  87. ncbi request reprint Management of earwax in primary care--postal survey of UK GPs and practice nurses
    Richard Coppin
    The Surgery, Overton, Hants, UK
    Fam Pract 21:413-4. 2004
  88. ncbi request reprint Delayed prescribing--a sensible approach to the management of acute otitis media
    Paul Little
    JAMA 296:1290-1. 2006
  89. ncbi request reprint Antibiotics for acute otitis media: a meta-analysis with individual patient data
    Maroeska M Rovers
    Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
    Lancet 368:1429-35. 2006
    ..We aimed to identify subgroups of children who would and would not benefit more than others from treatment with antibiotics...
  90. ncbi request reprint Predictors of pain and/or fever at 3 to 7 days for children with acute otitis media not treated initially with antibiotics: a meta-analysis of individual patient data
    Maroeska M Rovers
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
    Pediatrics 119:579-85. 2007
    ..The goal was to determine the predictors of a prolonged course for children with acute otitis media...
  91. doi request reprint Antibiotic prescribing for self limiting respiratory tract infections in primary care: summary of NICE guidance
    Toni Tan
    National Institute for Health and Clinical Excellence, Manchester M1 4BD
    BMJ 337:a437. 2008
  92. ncbi request reprint Community-acquired pneumonia mortality: a potential link to antibiotic prescribing trends in general practice
    David B Price
    Department of General Practice and Primary Care, Foresterhill Health Centre, University of Aberdeen, Westburn Road, Aberdeen AB25 2AY, UK
    Respir Med 98:17-24. 2004
    ..We examine the association between pneumonia mortality and recent changes in community-based antibiotic prescribing for lower respiratory tract infections (LRTI)...
  93. pmc Recurrent pharyngo-tonsillitis
    Paul Little
    BMJ 334:909. 2007
  94. pmc European Surveillance of Antimicrobial Consumption (ESAC): quality indicators for outpatient antibiotic use in Europe
    Samuel Coenen
    University of Antwerp Campus Drie Eiken, Department of General Practice, Universiteitsplein 1, 2610 Antwerp, Belgium
    Qual Saf Health Care 16:440-5. 2007
    ....
  95. pmc Earwax
    Richard Coppin
    Br J Gen Pract 58:284. 2008
  96. pmc A pain in the neck for steroids
    Michael Moore
    Br J Gen Pract 55:393; author reply 393-4. 2005
  97. pmc Preparing for the next flu pandemic
    Wei Shen Lim
    BMJ 334:268-9. 2007
  98. pmc Community acquired pneumonia in primary care
    Herman Goossens
    BMJ 332:1045-6. 2006