Arimantas LionikasSummaryAffiliation: University of Aberdeen Country: UK Publications
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Publications
Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analysesArimantas Lionikas
School of Medical Sciences, University of Aberdeen, Aberdeen, AB25 2ZD, UK
BMC Genomics 13:592. 2012..To facilitate nomination of the candidate genes responsible for these differences we examined the transcriptome of the tibialis anterior (TA) muscle of each strain by RNA-Seq...
QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strainsJuzoh Umemori
Mouse Genomics Resource Laboratory, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
BMC Genet 10:40. 2009..Here, we report on quantitative trait loci for different components of spontaneous activity, an important step towards dissection of the underlying genetic mechanisms...
Genomic analysis of variation in hindlimb musculature of mice from the C57BL/6J and DBA/2J lineageArimantas Lionikas
School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
J Hered 101:360-7. 2010..A panel of BXD RI strains is a useful tool in exploring the genetic mechanisms underlying SFAA and improving our understanding of musculoskeletal development...
Fine-mapping of muscle weight QTL in LG/J and SM/J intercrossesA Lionikas
School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom
Physiol Genomics 42:33-8. 2010..Combination of analyses in an F(2) and AI was an effective strategy to detect and refine the QTL in a genome-wide manner. The achieved resolution facilitates further elucidation of the underlying genetic mechanisms affecting muscle mass...
Constitutive expression of yes-associated protein (yap) in adult skeletal muscle fibres induces muscle atrophy and myopathyRobert N Judson
School of Medicine and Dentistry, University of Aberdeen, Aberdeen, United Kingdom
PLoS ONE 8:e59622. 2013..To conclude, high Yap activity in muscle fibres does not induce fibre hypertrophy nor fibre type changes but instead results in a reversible atrophy and deterioration...
H55N polymorphism as a likely cause of variation in citrate synthase activity of mouse skeletal muscleAivaras Ratkevicius
School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom
Physiol Genomics 42:96-102. 2010..In summary, H55N polymorphism in Cs could be the underlying cause of low CS activity and its high affinity for substrates in A/J mice compared with other strains. This SNP might also play a role in resistance to obesity of A/J mice...
QTL Analysis of Type I and Type IIA Fibers in Soleus Muscle in a Cross between LG/J and SM/J Mouse StrainsAndrew M Carroll
School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen Aberdeen, UK
Front Genet 2:99. 2011..Our results provide the evidence that the intercross between the SM/J and LG/J strains is a promising model to search for genes affecting muscle fiber properties...
