Research Topics
Species | Helen LingSummaryAffiliation: University College London Country: UK Publications
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Publications
Smoking-induced transient motor deterioration in a levodopa-treated patient with Parkinson's diseaseHelen Ling
Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK
J Neurol 259:2419-23. 2012..The potential mechanisms of the additive effect of levodopa and nicotine and paradoxical motor improvement after administration of high-dose nicotine via intranasal nicotine spray are also discussed...
Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's diseaseHelen Ling
Sara Koe PSP Research Centre, Institute of Neurology, University College London, UK
Brain 135:1141-53. 2012..Similarly, 'micrographia' and 'lack of decrement in script size' are also more common in progressive supranuclear palsy than in Parkinson's disease...
Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophyLuke A Massey
Sara Koe PSP Research Centre, UCL Institute of Neurology, University College London, London, United Kingdom
Mov Disord 27:1754-62. 2012..However, the low sensitivity of these and macroscopic findings at autopsy suggest a need for imaging techniques sensitive to microstructural abnormalities without regional atrophy...
MM2 subtype of sporadic Creutzfeldt-Jakob disease may underlie the clinical presentation of progressive supranuclear palsyIgor N Petrovic
Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology, 1 Wakefield St, London, WC1N 1PJ, UK
J Neurol 260:1031-6. 2013..This case and the literature support the notion that biochemical properties of the prion protein can influence the clinical presentation of sCJD...
Improvements in rate of development and magnitude of force with intense auditory stimuli in patients with Parkinson's diseaseAnam Anzak
Sobell Department of Motor Neuroscience and Movement Disorders, Queen Square, London, UK
Eur J Neurosci 34:124-32. 2011..The potential independence of the mediating pathways from the dopaminergic system provides impetus for further investigation as it may yield a novel nondopaminergic target for therapeutic manipulation in Parkinson's disease...
Decades of delayed diagnosis in 4 levodopa-responsive young-onset monogenetic parkinsonism patientsHelen Ling
Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, London, United Kingdom
Mov Disord 26:1337-40. 2011..We report 4 patients with young-onset monogenetic parkinsonism, each of whom was misdiagnosed with either a psychogenic movement disorder or chronic fatigue syndrome for 10 to 23 years after the onset of their first symptoms...
An intragenic duplication in guanosine triphosphate cyclohydrolase-1 gene in a dopa-responsive dystonia familyHelen Ling
Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, London, United Kingdom
Mov Disord 26:905-9. 2011..Autosomal dominant dopa-responsive dystonia is commonly caused by mutations in the guanosine triphosphate cyclohydrolase-1 gene...
Normal pressure hydrocephalus or progressive supranuclear palsy? A clinicopathological case seriesNadia K Magdalinou
Reta Lila Weston Institute of Neurological Studies, UCL, 1 Wakefield Street, London, WC1N 1PJ, UK
J Neurol 260:1009-13. 2013..An awareness that PSP or PD can mimic the clinical symptoms of iNPH may help to avoid invasive and futile cerebrospinal fluid shunting procedures...
The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological featuresEleanna Kara
Reta Lila Weston Laboratories and Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK
Neurobiol Aging 33:2231.e7-2231.e14. 2012..We suggest that the A152T variant is a risk factor associated with the development of atypical neurodegenerative conditions with abnormal tau accumulation...
Does corticobasal degeneration exist? A clinicopathological re-evaluationHelen Ling
Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, 1 Wakefield Street, London WC1N 1PJ, UK
Brain 133:2045-57. 2010..Despite these diagnostic difficulties we conclude that corticobasal degeneration is a discrete clinicopathological entity but with a broader clinical spectrum than was originally proposed...
