Helen Ling

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features
    Eleanna Kara
    Reta Lila Weston Laboratories and Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK
    Neurobiol Aging 33:2231.e7-2231.e14. 2012
  2. doi request reprint Smoking-induced transient motor deterioration in a levodopa-treated patient with Parkinson's disease
    Helen Ling
    Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK
    J Neurol 259:2419-23. 2012
  3. pmc Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease
    Helen Ling
    Sara Koe PSP Research Centre, Institute of Neurology, University College London, UK
    Brain 135:1141-53. 2012
  4. doi request reprint The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy
    Luke A Massey
    Sara Koe PSP Research Centre, Rita Lila Weston Institute for Neurology Studies and Queen Square Brain Bank, Department of Molecular Neurosciences, UCL Institute of Neurology, London, UK
    Neurology 80:1856-61. 2013
  5. doi request reprint Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy
    Luke A Massey
    Sara Koe PSP Research Centre, UCL Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 27:1754-62. 2012
  6. doi request reprint MM2 subtype of sporadic Creutzfeldt-Jakob disease may underlie the clinical presentation of progressive supranuclear palsy
    Igor N Petrovic
    Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology, 1 Wakefield St, London, WC1N 1PJ, UK
    J Neurol 260:1031-6. 2013
  7. doi request reprint Improvements in rate of development and magnitude of force with intense auditory stimuli in patients with Parkinson's disease
    Anam Anzak
    Sobell Department of Motor Neuroscience and Movement Disorders, Queen Square, London, UK
    Eur J Neurosci 34:124-32. 2011
  8. doi request reprint Decades of delayed diagnosis in 4 levodopa-responsive young-onset monogenetic parkinsonism patients
    Helen Ling
    Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 26:1337-40. 2011
  9. pmc α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?
    Aoife P Kiely
    Queen Square Brain Bank, UCL Institute of Neurology, London, UK
    Acta Neuropathol 125:753-69. 2013
  10. doi request reprint An intragenic duplication in guanosine triphosphate cyclohydrolase-1 gene in a dopa-responsive dystonia family
    Helen Ling
    Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 26:905-9. 2011

Collaborators

Detail Information

Publications12

  1. pmc The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features
    Eleanna Kara
    Reta Lila Weston Laboratories and Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK
    Neurobiol Aging 33:2231.e7-2231.e14. 2012
    ..We suggest that the A152T variant is a risk factor associated with the development of atypical neurodegenerative conditions with abnormal tau accumulation...
  2. doi request reprint Smoking-induced transient motor deterioration in a levodopa-treated patient with Parkinson's disease
    Helen Ling
    Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, 1 Wakefield Street, London, WC1N 1PJ, UK
    J Neurol 259:2419-23. 2012
    ..The potential mechanisms of the additive effect of levodopa and nicotine and paradoxical motor improvement after administration of high-dose nicotine via intranasal nicotine spray are also discussed...
  3. pmc Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease
    Helen Ling
    Sara Koe PSP Research Centre, Institute of Neurology, University College London, UK
    Brain 135:1141-53. 2012
    ..Similarly, 'micrographia' and 'lack of decrement in script size' are also more common in progressive supranuclear palsy than in Parkinson's disease...
  4. doi request reprint The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy
    Luke A Massey
    Sara Koe PSP Research Centre, Rita Lila Weston Institute for Neurology Studies and Queen Square Brain Bank, Department of Molecular Neurosciences, UCL Institute of Neurology, London, UK
    Neurology 80:1856-61. 2013
    ..We aimed to develop in histologically proven disease a simple measure of the midbrain and pons on sagittal MRI to identify PSP...
  5. doi request reprint Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy
    Luke A Massey
    Sara Koe PSP Research Centre, UCL Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 27:1754-62. 2012
    ..However, the low sensitivity of these and macroscopic findings at autopsy suggest a need for imaging techniques sensitive to microstructural abnormalities without regional atrophy...
  6. doi request reprint MM2 subtype of sporadic Creutzfeldt-Jakob disease may underlie the clinical presentation of progressive supranuclear palsy
    Igor N Petrovic
    Reta Lila Weston Institute of Neurological Studies, UCL Institute of Neurology, 1 Wakefield St, London, WC1N 1PJ, UK
    J Neurol 260:1031-6. 2013
    ..This case and the literature support the notion that biochemical properties of the prion protein can influence the clinical presentation of sCJD...
  7. doi request reprint Improvements in rate of development and magnitude of force with intense auditory stimuli in patients with Parkinson's disease
    Anam Anzak
    Sobell Department of Motor Neuroscience and Movement Disorders, Queen Square, London, UK
    Eur J Neurosci 34:124-32. 2011
    ..The potential independence of the mediating pathways from the dopaminergic system provides impetus for further investigation as it may yield a novel nondopaminergic target for therapeutic manipulation in Parkinson's disease...
  8. doi request reprint Decades of delayed diagnosis in 4 levodopa-responsive young-onset monogenetic parkinsonism patients
    Helen Ling
    Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 26:1337-40. 2011
    ..We report 4 patients with young-onset monogenetic parkinsonism, each of whom was misdiagnosed with either a psychogenic movement disorder or chronic fatigue syndrome for 10 to 23 years after the onset of their first symptoms...
  9. pmc α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?
    Aoife P Kiely
    Queen Square Brain Bank, UCL Institute of Neurology, London, UK
    Acta Neuropathol 125:753-69. 2013
    ..Greater understanding of the disease mechanism underlying the G51D mutation could aid in understanding of α-synuclein biology and its impact on disease phenotype...
  10. doi request reprint An intragenic duplication in guanosine triphosphate cyclohydrolase-1 gene in a dopa-responsive dystonia family
    Helen Ling
    Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 26:905-9. 2011
    ..Autosomal dominant dopa-responsive dystonia is commonly caused by mutations in the guanosine triphosphate cyclohydrolase-1 gene...
  11. doi request reprint Normal pressure hydrocephalus or progressive supranuclear palsy? A clinicopathological case series
    Nadia K Magdalinou
    Reta Lila Weston Institute of Neurological Studies, UCL, 1 Wakefield Street, London, WC1N 1PJ, UK
    J Neurol 260:1009-13. 2013
    ..An awareness that PSP or PD can mimic the clinical symptoms of iNPH may help to avoid invasive and futile cerebrospinal fluid shunting procedures...
  12. doi request reprint Does corticobasal degeneration exist? A clinicopathological re-evaluation
    Helen Ling
    Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, 1 Wakefield Street, London WC1N 1PJ, UK
    Brain 133:2045-57. 2010
    ..Despite these diagnostic difficulties we conclude that corticobasal degeneration is a discrete clinicopathological entity but with a broader clinical spectrum than was originally proposed...