Katharine E Lewis

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons
    Manuel F Batista
    Department of Physiology, Development and Neuroscience, Anatomy Building, Downing Street, Cambridge CB2 3DY, UK
    Dev Biol 323:88-97. 2008
  2. pmc Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates
    Karl R Wotton
    King s College London, Department of Craniofacial Development, Floor 27 Guy s Tower, Guy s Hospital, London Bridge, London, SE1 9RT, UK
    BMC Evol Biol 8:171. 2008
  3. ncbi request reprint Regulation of iro3 expression in the zebrafish spinal cord
    Katharine E Lewis
    Institute of Neuroscience, University of Oregon, Eugene, Oregon, USA
    Dev Dyn 232:140-8. 2005
  4. pmc How do genes regulate simple behaviours? Understanding how different neurons in the vertebrate spinal cord are genetically specified
    Katharine E Lewis
    Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    Philos Trans R Soc Lond B Biol Sci 361:45-66. 2006
  5. doi request reprint Zebrafish V2 cells develop into excitatory CiD and Notch signalling dependent inhibitory VeLD interneurons
    Manuel F Batista
    Department of Physiology, Development and Neuroscience, University of Cambridge, Anatomy Building, Downing Street, Cambridge, UK
    Dev Biol 322:263-75. 2008
  6. doi request reprint RNA profiling of FAC-sorted neurons from the developing zebrafish spinal cord
    Gustavo A Cerda
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    Dev Dyn 238:150-61. 2009
  7. doi request reprint Evx1 is required for joint formation in zebrafish fin dermoskeleton
    Claus J Schulte
    Department of Physiology, Development and Neuroscience, Anatomy Building, Cambridge, UK
    Dev Dyn 240:1240-8. 2011
  8. ncbi request reprint Paraxial mesoderm specifies zebrafish primary motoneuron subtype identity
    Katharine E Lewis
    Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403, USA
    Development 131:891-902. 2004
  9. pmc Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events
    Debbie K Goode
    Department of Physiology Development and Neuroscience, Anatomy Building, Downing Street, Cambridge, UK
    Development 138:879-84. 2011
  10. ncbi request reprint From cells to circuits: development of the zebrafish spinal cord
    Katharine E Lewis
    Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403, USA
    Prog Neurobiol 69:419-49. 2003

Collaborators

  • Judith Eisen
  • Greg Elgar
  • William A Harris
  • Sudipto Roy
  • Debbie K Goode
  • Manuel F Batista
  • Claus J Schulte
  • Gustavo A Cerda
  • Karl R Wotton
  • Giuseppe Lupo
  • Christian Wolff
  • José L Juárez-Morales
  • Samantha J England
  • Claire Allen
  • Murray Hargrave
  • Susanne Dietrich
  • Jeffrey Jacobstein
  • Frida K Weierud
  • Heike Schauerte
  • Gerd Joerg-Rauch
  • Pascal Haffter
  • Christian Weiler
  • Robert Geisler
  • Annette Kirn
  • Philip W Ingham

Detail Information

Publications12

  1. pmc Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneurons
    Manuel F Batista
    Department of Physiology, Development and Neuroscience, Anatomy Building, Downing Street, Cambridge CB2 3DY, UK
    Dev Biol 323:88-97. 2008
    ....
  2. pmc Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates
    Karl R Wotton
    King s College London, Department of Craniofacial Development, Floor 27 Guy s Tower, Guy s Hospital, London Bridge, London, SE1 9RT, UK
    BMC Evol Biol 8:171. 2008
    ..Which of these genes were maintained in extant vertebrates, and how these genes and their functions evolved, is not known...
  3. ncbi request reprint Regulation of iro3 expression in the zebrafish spinal cord
    Katharine E Lewis
    Institute of Neuroscience, University of Oregon, Eugene, Oregon, USA
    Dev Dyn 232:140-8. 2005
    ..We discuss our findings in the context of previous studies, suggesting that iro3 represses formation of motoneurons and promotes formation of interneurons...
  4. pmc How do genes regulate simple behaviours? Understanding how different neurons in the vertebrate spinal cord are genetically specified
    Katharine E Lewis
    Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    Philos Trans R Soc Lond B Biol Sci 361:45-66. 2006
    ....
  5. doi request reprint Zebrafish V2 cells develop into excitatory CiD and Notch signalling dependent inhibitory VeLD interneurons
    Manuel F Batista
    Department of Physiology, Development and Neuroscience, University of Cambridge, Anatomy Building, Downing Street, Cambridge, UK
    Dev Biol 322:263-75. 2008
    ..In addition, we demonstrate that Notch signalling is required for V2 cells to develop into V2b cells. In the absence of Notch signalling, all V2b cells develop as V2a cells...
  6. doi request reprint RNA profiling of FAC-sorted neurons from the developing zebrafish spinal cord
    Gustavo A Cerda
    Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, United Kingdom
    Dev Dyn 238:150-61. 2009
    ..This protocol for dissociating, sorting and RNA-profiling neurons from organogenesis-stage zebrafish embryos should also be applicable to other developing organs and tissues and potentially other model organisms...
  7. doi request reprint Evx1 is required for joint formation in zebrafish fin dermoskeleton
    Claus J Schulte
    Department of Physiology, Development and Neuroscience, Anatomy Building, Cambridge, UK
    Dev Dyn 240:1240-8. 2011
    ..This is a very specific phenotype as both lepidotrichia hemisegment separations and lepidotrichia bifurcations still form normally in evx1 mutant fins, as do joints in the more proximal endoskeletal radials...
  8. ncbi request reprint Paraxial mesoderm specifies zebrafish primary motoneuron subtype identity
    Katharine E Lewis
    Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403, USA
    Development 131:891-902. 2004
    ..Our findings suggest that in the absence of signals from paraxial mesoderm, primary motoneurons have a hybrid identity with respect to gene expression, and that under these conditions the CaP axon trajectory may be dominant...
  9. pmc Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication events
    Debbie K Goode
    Department of Physiology Development and Neuroscience, Anatomy Building, Downing Street, Cambridge, UK
    Development 138:879-84. 2011
    ..Therefore, if CNEs are to be used as candidate enhancers for transgenic studies or for multi-species comparative analyses, it is paramount that the CNEs are accurately delineated...
  10. ncbi request reprint From cells to circuits: development of the zebrafish spinal cord
    Katharine E Lewis
    Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403, USA
    Prog Neurobiol 69:419-49. 2003
    ..We next describe axon pathfinding of spinal neurons. Finally, we discuss the roles of particular spinal cord neurons in specific behaviors...
  11. ncbi request reprint Mechanisms of ventral patterning in the vertebrate nervous system
    Giuseppe Lupo
    Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
    Nat Rev Neurosci 7:103-14. 2006
    ..Here, we discuss recent advances in this field, highlighting the emerging interplay of these signalling pathways in the molecular specification of ventral patterning at different rostrocaudal levels of the CNS...
  12. pmc iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo
    Christian Wolff
    Center for Developmental Genetics, School of Medicine and Biomedical Sciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK
    Genes Dev 18:1565-76. 2004
    ....