Research Topics
Genomes and GenesSpecies | Katharine E LewisSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebratesKarl R Wotton
King s College London, Department of Craniofacial Development, Floor 27 Guy s Tower, Guy s Hospital, London Bridge, London, SE1 9RT, UK
BMC Evol Biol 8:171. 2008..Which of these genes were maintained in extant vertebrates, and how these genes and their functions evolved, is not known...- How do genes regulate simple behaviours? Understanding how different neurons in the vertebrate spinal cord are genetically specifiedKatharine E Lewis
Department of Anatomy, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
Philos Trans R Soc Lond B Biol Sci 361:45-66. 2006.... - Regulation of iro3 expression in the zebrafish spinal cordKatharine E Lewis
Institute of Neuroscience, University of Oregon, Eugene, Oregon, USA
Dev Dyn 232:140-8. 2005..We discuss our findings in the context of previous studies, suggesting that iro3 represses formation of motoneurons and promotes formation of interneurons... - Pax2/8 act redundantly to specify glycinergic and GABAergic fates of multiple spinal interneuronsManuel F Batista
Department of Physiology, Development and Neuroscience, Anatomy Building, Downing Street, Cambridge CB2 3DY, UK
Dev Biol 323:88-97. 2008.... - Zebrafish V2 cells develop into excitatory CiD and Notch signalling dependent inhibitory VeLD interneuronsManuel F Batista
Department of Physiology, Development and Neuroscience, University of Cambridge, Anatomy Building, Downing Street, Cambridge, UK
Dev Biol 322:263-75. 2008..In addition, we demonstrate that Notch signalling is required for V2 cells to develop into V2b cells. In the absence of Notch signalling, all V2b cells develop as V2a cells... - Paraxial mesoderm specifies zebrafish primary motoneuron subtype identityKatharine E Lewis
Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403, USA
Development 131:891-902. 2004..Our findings suggest that in the absence of signals from paraxial mesoderm, primary motoneurons have a hybrid identity with respect to gene expression, and that under these conditions the CaP axon trajectory may be dominant... - From cells to circuits: development of the zebrafish spinal cordKatharine E Lewis
Institute of Neuroscience, 1254 University of Oregon, Eugene, OR 97403, USA
Prog Neurobiol 69:419-49. 2003..We next describe axon pathfinding of spinal neurons. Finally, we discuss the roles of particular spinal cord neurons in specific behaviors... - Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication eventsDebbie K Goode
Department of Physiology Development and Neuroscience, Anatomy Building, Downing Street, Cambridge, UK
Development 138:879-84. 2011..Therefore, if CNEs are to be used as candidate enhancers for transgenic studies or for multi-species comparative analyses, it is paramount that the CNEs are accurately delineated... - Mechanisms of ventral patterning in the vertebrate nervous systemGiuseppe Lupo
Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3DY, UK
Nat Rev Neurosci 7:103-14. 2006..Here, we discuss recent advances in this field, highlighting the emerging interplay of these signalling pathways in the molecular specification of ventral patterning at different rostrocaudal levels of the CNS... - iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryoChristian Wolff
Center for Developmental Genetics, School of Medicine and Biomedical Sciences, University of Sheffield, Western Bank, Sheffield S10 2TN, UK
Genes Dev 18:1565-76. 2004....