Tim P Levine

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Short-range intracellular trafficking of small molecules across endoplasmic reticulum junctions
    Tim Levine
    Division of Cell Biology, Institute of Ophthalmology, Bath Street, London EC1V 9EL, UK
    Trends Cell Biol 14:483-90. 2004
  2. ncbi Inter-organelle membrane contact sites: through a glass, darkly
    Tim Levine
    Division of Cell Biology, UCL Institute of Ophthalmology, Bath St, London EC1V 9EL, UK
    Curr Opin Cell Biol 18:371-8. 2006
  3. ncbi A lipid transfer protein that transfers lipid
    Tim P Levine
    University College London Institute of Ophthalmology, London EC1V 9EL, England, UK
    J Cell Biol 179:11-3. 2007
  4. ncbi Lipid traffic: Osh4p makes an unexpected exchange
    Tim P Levine
    Institute of Ophthalmology, University College London, London EC1V 9EL, England, UK
    J Cell Biol 195:927-9. 2011
  5. ncbi Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate
    Matthew J Hayes
    Division of Cell Biology, UCL Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
    Biochim Biophys Acta 1793:1086-95. 2009
  6. ncbi Endoplasmic reticulum: one continuous network compartmentalized by extrinsic cues
    Tim Levine
    Division of Cell Biology, Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK
    Curr Opin Cell Biol 17:362-8. 2005
  7. ncbi SSD: sterol-sensing direct
    Tim Levine
    Division of Cell Biology, Institute of Ophthalmology, Bath Street, London EC1V 9EL, United Kingdom
    Dev Cell 7:152-3. 2004
  8. ncbi Lipid traffic: floppy drives and a superhighway
    Joost C M Holthuis
    Department of Membrane Enzymology, Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Nat Rev Mol Cell Biol 6:209-20. 2005

Detail Information

Publications8

  1. ncbi Short-range intracellular trafficking of small molecules across endoplasmic reticulum junctions
    Tim Levine
    Division of Cell Biology, Institute of Ophthalmology, Bath Street, London EC1V 9EL, UK
    Trends Cell Biol 14:483-90. 2004
    ..In the light of these advances, I hypothesize that the endoplasmic reticulum has a central role in the trafficking of lipids and ions by forming a network of MCSs with most other intracellular organelles...
  2. ncbi Inter-organelle membrane contact sites: through a glass, darkly
    Tim Levine
    Division of Cell Biology, UCL Institute of Ophthalmology, Bath St, London EC1V 9EL, UK
    Curr Opin Cell Biol 18:371-8. 2006
    ..Further work will be needed to test whether these lipid transfer proteins act when anchored at inter-organelle contact sites...
  3. ncbi A lipid transfer protein that transfers lipid
    Tim P Levine
    University College London Institute of Ophthalmology, London EC1V 9EL, England, UK
    J Cell Biol 179:11-3. 2007
    ..Godi, G. West, J. Bielawski, C.C. Chuang, A.C. van der Spoel, et al. 2007. Nature. 449:62-67) agree that four-phosphate adaptor protein 2 (FAPP2) transfers glucosylceramide (GlcCer), a lipid that takes an unexpectedly circuitous route...
  4. ncbi Lipid traffic: Osh4p makes an unexpected exchange
    Tim P Levine
    Institute of Ophthalmology, University College London, London EC1V 9EL, England, UK
    J Cell Biol 195:927-9. 2011
    ..This finding helps explain some previously published studies and also indicates that lipid/sterol exchange could contribute to establishing a sterol gradient in cells...
  5. ncbi Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate
    Matthew J Hayes
    Division of Cell Biology, UCL Institute of Ophthalmology, University College London, 11 43 Bath Street, London EC1V 9EL, UK
    Biochim Biophys Acta 1793:1086-95. 2009
    ..These observations are consistent with a role for annexin A2 as an actin nucleator on PI(4,5)P2-enriched membranes...
  6. ncbi Endoplasmic reticulum: one continuous network compartmentalized by extrinsic cues
    Tim Levine
    Division of Cell Biology, Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL, UK
    Curr Opin Cell Biol 17:362-8. 2005
    ....
  7. ncbi SSD: sterol-sensing direct
    Tim Levine
    Division of Cell Biology, Institute of Ophthalmology, Bath Street, London EC1V 9EL, United Kingdom
    Dev Cell 7:152-3. 2004
    ..New biochemical studies of this domain demonstrate direct high-affinity binding of the sterol-sensing domain to sterol...
  8. ncbi Lipid traffic: floppy drives and a superhighway
    Joost C M Holthuis
    Department of Membrane Enzymology, Institute of Biomembranes, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands
    Nat Rev Mol Cell Biol 6:209-20. 2005
    ..These include transbilayer flip-flop mechanisms and transfer across narrow gaps between the endoplasmic reticulum and other organelles, with the endoplasmic reticulum functioning as a superhighway along which lipids can rapidly diffuse...