Amy Leslie

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. ncbi request reprint Colonoscopy
    A Leslie
    University Department of Surgery and Molecular Oncology, Ninewells Hospital, Dundee, UK
    J R Coll Surg Edinb 47:502-9. 2002
  2. ncbi request reprint The colorectal adenoma-carcinoma sequence
    A Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital, Dundee, UK
    Br J Surg 89:845-60. 2002
  3. ncbi request reprint Lower gastrointestinal symptoms are not predictive of colorectal neoplasia in a faecal occult blood screen-positive population
    S Ahmed
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK
    Br J Surg 92:478-81. 2005
  4. ncbi request reprint The interrupted serosubmucosal anastomosis - still the gold standard
    A Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Dundee, UK
    Colorectal Dis 5:362-6. 2003
  5. ncbi request reprint Mutations of APC, K-ras, and p53 are associated with specific chromosomal aberrations in colorectal adenocarcinomas
    Amy Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, Scotland, UK
    Cancer Res 63:4656-61. 2003
  6. ncbi request reprint Chromosomal changes in colorectal adenomas: relationship to gene mutations and potential for clinical utility
    Amy Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital, United Kingdom
    Genes Chromosomes Cancer 45:126-35. 2006
  7. ncbi request reprint Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas
    H Judson
    Department of Human Genetics, Ninewells Hospital and University of Dundee, Dundee, UK
    J Pathol 210:344-50. 2006
  8. pmc Management of colorectal cancer
    A Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    Postgrad Med J 78:473-8. 2002

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Colonoscopy
    A Leslie
    University Department of Surgery and Molecular Oncology, Ninewells Hospital, Dundee, UK
    J R Coll Surg Edinb 47:502-9. 2002
    ..In this article, the key steps in performing colonoscopy are described with a view to providing the trainee with a logical sequence of manoeuvres on which to base a sound technique...
  2. ncbi request reprint The colorectal adenoma-carcinoma sequence
    A Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital, Dundee, UK
    Br J Surg 89:845-60. 2002
    ..The evidence supporting this hypothesis has increased rapidly in recent years and the purpose of this article is to review this evidence critically and highlight its clinical significance...
  3. ncbi request reprint Lower gastrointestinal symptoms are not predictive of colorectal neoplasia in a faecal occult blood screen-positive population
    S Ahmed
    Department of Surgery and Molecular Oncology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK
    Br J Surg 92:478-81. 2005
    ....
  4. ncbi request reprint The interrupted serosubmucosal anastomosis - still the gold standard
    A Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Dundee, UK
    Colorectal Dis 5:362-6. 2003
    ..This report describes the results of these operations, the results of stapled anastomoses carried out during the same period and discusses the utility of the handsewn technique...
  5. ncbi request reprint Mutations of APC, K-ras, and p53 are associated with specific chromosomal aberrations in colorectal adenocarcinomas
    Amy Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, Scotland, UK
    Cancer Res 63:4656-61. 2003
    ..011). The associations we have described should refine the search for candidate genes underlying chromosomal aberrations and assist in the definition of distinct pathways in colorectal tumorigenesis...
  6. ncbi request reprint Chromosomal changes in colorectal adenomas: relationship to gene mutations and potential for clinical utility
    Amy Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital, United Kingdom
    Genes Chromosomes Cancer 45:126-35. 2006
    ..Our findings also raise the possibility that certain chromosomal aberrations may act as important clinical biomarkers...
  7. ncbi request reprint Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas
    H Judson
    Department of Human Genetics, Ninewells Hospital and University of Dundee, Dundee, UK
    J Pathol 210:344-50. 2006
    ..We conclude that methylation abnormality is very common in pre-invasive colorectal neoplasia, and that high level methylation is associated with low level chromosomal instability...
  8. pmc Management of colorectal cancer
    A Leslie
    Department of Surgery and Molecular Oncology, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
    Postgrad Med J 78:473-8. 2002
    ..The treatment of advanced disease is still essentially palliative, although surgery for limited hepatic metastases may be curative in a small proportion of patients...