Corinne Lendon

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. ncbi No effect of apolipoprotein E on neuronal cell death due to excitotoxic and apoptotic agents in vitro and neonatal hypoxic ischaemia in vivo
    C L Lendon
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, UK
    Eur J Neurosci 12:2235-42. 2000
  2. ncbi Susceptibility gene(s) for Alzheimer's disease on chromosome 10
    C Lendon
    Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK B15 2QZ
    Trends Neurosci 24:557-9. 2001
  3. ncbi Genetic variation of the APOE promoter and outcome after head injury
    C L Lendon
    Department of Psychiatry, University of Birmingham, UK
    Neurology 61:683-5. 2003
  4. ncbi No association between polymorphisms in the lectin-like oxidised low density lipoprotein receptor (ORL1) gene on chromosome 12 and Alzheimer's disease in a UK cohort
    Antonia Pritchard
    Molecular Psychiatry Department, Division of Neuroscience, Queen Elizabeth Psychiatric Hospital, University of Birmingham, Birmingham B15 2QZ, UK
    Neurosci Lett 366:126-9. 2004
  5. ncbi Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease
    Antonia Pritchard
    Molecular Psychiatry Department, Division of Neuroscience, Queen Elizabeth Psychiatric Hospital, University of Birmingham, Birmingham B15 2QZ, UK
    Neurosci Lett 382:221-6. 2005
  6. ncbi Variation in the coding sequence and flanking splice junctions of the estrogen receptor alpha (ERalpha) gene does not play an important role in genetic susceptibility to bipolar disorder or bipolar affective puerperal psychosis
    Fiona Middle
    Division of Neuroscience, Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
    Am J Med Genet B Neuropsychiatr Genet 118:72-5. 2003
  7. doi Association study of the NEDD9 gene with the risk of developing Alzheimer's and Parkinson's disease
    Julien Chapuis
    INSERM, U744, Institut Pasteur de Lille, Universite de Lille 2, Lille, France
    Hum Mol Genet 17:2863-7. 2008
  8. doi Association study of the GAB2 gene with the risk of developing Alzheimer's disease
    Julien Chapuis
    INSERM, U744, Institut Pasteur de Lille, Universite de Lille 2, Lille, France
    Neurobiol Dis 30:103-6. 2008
  9. ncbi Association study of the Ubiquilin gene with Alzheimer's disease
    Faiza Bensemain
    INSERM U744, Institut Pasteur de Lille, Universite de Lille 2, Lille, BP 245, 5019 Lille Cédex, France
    Neurobiol Dis 22:691-3. 2006
  10. ncbi A 3'-UTR polymorphism in the oxidized LDL receptor 1 gene increases Abeta40 load as cerebral amyloid angiopathy in Alzheimer's disease
    Jing Shi
    Clinical Neuroscience Research Group, University of Manchester, Hope Hospital, Salford, M6 8HD, UK
    Acta Neuropathol 111:15-20. 2006

Collaborators

Detail Information

Publications14

  1. ncbi No effect of apolipoprotein E on neuronal cell death due to excitotoxic and apoptotic agents in vitro and neonatal hypoxic ischaemia in vivo
    C L Lendon
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, UK
    Eur J Neurosci 12:2235-42. 2000
    ..This suggests that if apoE does modify the extent of brain damage and recovery after injury, it seems unlikely to be a result of direct or indirect modulation of excitotoxic or apoptotic cell death...
  2. ncbi Susceptibility gene(s) for Alzheimer's disease on chromosome 10
    C Lendon
    Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK B15 2QZ
    Trends Neurosci 24:557-9. 2001
    ..A third candidate gene linkage and association analysis approach interestingly finds a maximum signal approximately 35-60cM distal to the previous studies...
  3. ncbi Genetic variation of the APOE promoter and outcome after head injury
    C L Lendon
    Department of Psychiatry, University of Birmingham, UK
    Neurology 61:683-5. 2003
    ..The group with unfavorable outcome had a genotype frequency distribution similar to that found in AD...
  4. ncbi No association between polymorphisms in the lectin-like oxidised low density lipoprotein receptor (ORL1) gene on chromosome 12 and Alzheimer's disease in a UK cohort
    Antonia Pritchard
    Molecular Psychiatry Department, Division of Neuroscience, Queen Elizabeth Psychiatric Hospital, University of Birmingham, Birmingham B15 2QZ, UK
    Neurosci Lett 366:126-9. 2004
    ..Therefore, in this present study, we find no evidence for the involvement of these ORL1 polymorphisms in increasing susceptibility to AD...
  5. ncbi Association study and meta-analysis of low-density lipoprotein receptor related protein in Alzheimer's disease
    Antonia Pritchard
    Molecular Psychiatry Department, Division of Neuroscience, Queen Elizabeth Psychiatric Hospital, University of Birmingham, Birmingham B15 2QZ, UK
    Neurosci Lett 382:221-6. 2005
    ..Therefore, in this present study, we find no evidence for the involvement of this polymorphism either in increasing the susceptibility to AD, or by acting as a phenotypic modifier...
  6. ncbi Variation in the coding sequence and flanking splice junctions of the estrogen receptor alpha (ERalpha) gene does not play an important role in genetic susceptibility to bipolar disorder or bipolar affective puerperal psychosis
    Fiona Middle
    Division of Neuroscience, Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
    Am J Med Genet B Neuropsychiatr Genet 118:72-5. 2003
    ..We conclude that variation in the coding sequence and flanking splice junctions of the ERalpha gene does not play an important pathogenic role in the majority of cases of Bipolar Disorder or Bipolar Affective Puerperal Psychosis...
  7. doi Association study of the NEDD9 gene with the risk of developing Alzheimer's and Parkinson's disease
    Julien Chapuis
    INSERM, U744, Institut Pasteur de Lille, Universite de Lille 2, Lille, France
    Hum Mol Genet 17:2863-7. 2008
    ..In conclusion, these data indicate that the rs760678 SNP of the NEDD9 gene is at best a weak genetic determinant of AD or PD...
  8. doi Association study of the GAB2 gene with the risk of developing Alzheimer's disease
    Julien Chapuis
    INSERM, U744, Institut Pasteur de Lille, Universite de Lille 2, Lille, France
    Neurobiol Dis 30:103-6. 2008
    ..3, 95%CI 1.0-1.6, p=0.05) in varepsilon4-carriers. In addition, the rs2373115 did not modulate the extent of tau phosphorylation in the brain of 89 AD cases. The GAB2 gene is at best a minor genetic determinant of AD...
  9. ncbi Association study of the Ubiquilin gene with Alzheimer's disease
    Faiza Bensemain
    INSERM U744, Institut Pasteur de Lille, Universite de Lille 2, Lille, BP 245, 5019 Lille Cédex, France
    Neurobiol Dis 22:691-3. 2006
    ..Furthermore, no relationship between this polymorphism and Abeta load or degree of neurofibrillary degeneration in the brains of 114 patients with AD was detected...
  10. ncbi A 3'-UTR polymorphism in the oxidized LDL receptor 1 gene increases Abeta40 load as cerebral amyloid angiopathy in Alzheimer's disease
    Jing Shi
    Clinical Neuroscience Research Group, University of Manchester, Hope Hospital, Salford, M6 8HD, UK
    Acta Neuropathol 111:15-20. 2006
    ....
  11. ncbi Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease
    Julien Chapuis
    Unité INSERM 508, Institut Pasteur de Lille, 1 rue du Professeur Calmette, BP 245, 59019 Lille Cedex, France
    Neurobiol Aging 27:1212-5. 2006
    ..Our data indicate that although this polymorphism is functional, it does not confer greater risk for AD, nor modulate the extent of vascular pathology...
  12. ncbi Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease
    Lynnette J Cook
    Department of Medical Genetics, Cambridge Institute for Medical Research, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2XY, UK
    Neurosci Lett 358:142-6. 2004
    ..70, 95% confidence interval=0.52-0.95, P=0.019). These data suggest that this variant warrants further examination in large case-control series...
  13. pmc A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk
    Ute Dreses-Werringloer
    Litwin Zucker Research Center for the Study of Alzheimer s Disease, The Feinstein Institute for Medical Research, North Shore LIJ, Manhasset, NY 11030, USA
    Cell 133:1149-61. 2008
    ..We propose that CALHM1 encodes an essential component of a previously uncharacterized cerebral Ca(2+) channel that controls Abeta levels and susceptibility to late-onset AD...
  14. ncbi Platelet glycoprotein polymorphisms: risk, in vivo expression and severity of atherothrombotic stroke in Chinese
    Yong Zhang
    Department of Neurology, Peking University First Hospital, Beijing, 100034, China
    Clin Chim Acta 378:99-104. 2007
    ..We also determined whether these polymorphisms were associated with in vivo expression levels of platelet GP receptors and the severity of the neurological deficit...