Kirsten Legerlotz

Summary

Affiliation: University of East Anglia
Country: UK

Publications

  1. pmc Cyclic loading of tendon fascicles using a novel fatigue loading system increases interleukin-6 expression by tenocytes
    K Legerlotz
    School of Biological Sciences, University of East Anglia, Norwich, UK
    Scand J Med Sci Sports 23:31-7. 2013
  2. pmc Increased expression of IL-6 family members in tendon pathology
    Kirsten Legerlotz
    School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK
    Rheumatology (Oxford) 51:1161-5. 2012
  3. pmc Cyclical strain modulates metalloprotease and matrix gene expression in human tenocytes via activation of TGFβ
    Eleanor R Jones
    Soft Tissue Research Group, School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK Electronic address
    Biochim Biophys Acta 1833:2596-607. 2013
  4. pmc GAG depletion increases the stress-relaxation response of tendon fascicles, but does not influence recovery
    Kirsten Legerlotz
    School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK
    Acta Biomater 9:6860-6. 2013

Detail Information

Publications4

  1. pmc Cyclic loading of tendon fascicles using a novel fatigue loading system increases interleukin-6 expression by tenocytes
    K Legerlotz
    School of Biological Sciences, University of East Anglia, Norwich, UK
    Scand J Med Sci Sports 23:31-7. 2013
    ..Correlating failure properties with fatigue damage provides a method by which changes in gene expression can be associated with different degrees of fatigue damage...
  2. pmc Increased expression of IL-6 family members in tendon pathology
    Kirsten Legerlotz
    School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK
    Rheumatology (Oxford) 51:1161-5. 2012
    ..The aim of this study was to investigate the expression of IL-6 family members in painful posterior tibialis tendon (PTT) and in painful and ruptured Achilles tendon (AT) compared with normal tendon...
  3. pmc Cyclical strain modulates metalloprotease and matrix gene expression in human tenocytes via activation of TGFβ
    Eleanor R Jones
    Soft Tissue Research Group, School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK Electronic address
    Biochim Biophys Acta 1833:2596-607. 2013
    ..We concluded that TGFβ activation plays an important role in mechanotransduction. Targeting this pathway may have its place in the treatment of tendinopathy. ..
  4. pmc GAG depletion increases the stress-relaxation response of tendon fascicles, but does not influence recovery
    Kirsten Legerlotz
    School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary University of London, UK
    Acta Biomater 9:6860-6. 2013
    ..GAGs appear to protect tendon fascicles from fatigue effects, possibly by enabling sample hydration...