A P Leff

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc The cortical dynamics of intelligible speech
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom
    J Neurosci 28:13209-15. 2008
  2. pmc The left superior temporal gyrus is a shared substrate for auditory short-term memory and speech comprehension: evidence from 210 patients with stroke
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, 12 Queen Square, London WC1N 3BG, UK
    Brain 132:3401-10. 2009
  3. pmc Vowel-specific mismatch responses in the anterior superior temporal gyrus: an fMRI study
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, London, UK
    Cortex 45:517-26. 2009
  4. pmc Structural anatomy of pure and hemianopic alexia
    A P Leff
    MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK
    J Neurol Neurosurg Psychiatry 77:1004-7. 2006
  5. doi request reprint Treatment of reading impairment after stroke
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, UK
    Curr Opin Neurol 21:644-8. 2008
  6. ncbi request reprint The functional anatomy of single-word reading in patients with hemianopic and pure alexia
    A P Leff
    MRC Clinical Sciences Centre, Cyclotron Unit, Hammersmith Hospital, London W12 0NN, UK
    Brain 124:510-21. 2001
  7. pmc How number processing survives left occipito-temporal damage
    M Cappelletti
    Institute of Cognitive Neuroscience, University College London, London, UK
    Neurocase 18:271-85. 2012
  8. pmc Changing meaning causes coupling changes within higher levels of the cortical hierarchy
    T M Schofield
    Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom
    Proc Natl Acad Sci U S A 106:11765-70. 2009
  9. ncbi request reprint Lesion sites that predict the ability to gesture how an object is used
    C J Price
    Wellcome Trust Centre for Neuro imaging, Institute of Neurology, University College London, UK
    Arch Ital Biol 148:243-58. 2010
  10. ncbi request reprint The planning and guiding of reading saccades: a repetitive transcranial magnetic stimulation study
    A P Leff
    Medical Research Council Cyclotron Unit and Imperial College School of Medicine, Hammersmith Hospital, London W12 0NN, UK
    Cereb Cortex 11:918-23. 2001

Detail Information

Publications14

  1. pmc The cortical dynamics of intelligible speech
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, University College London, London, United Kingdom
    J Neurosci 28:13209-15. 2008
    ..Task-related, directional effects can now be incorporated into models of speech comprehension...
  2. pmc The left superior temporal gyrus is a shared substrate for auditory short-term memory and speech comprehension: evidence from 210 patients with stroke
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, UCL, 12 Queen Square, London WC1N 3BG, UK
    Brain 132:3401-10. 2009
    ..The method applied here will be particularly useful for modelling structure-function relationships within other complex cognitive domains...
  3. pmc Vowel-specific mismatch responses in the anterior superior temporal gyrus: an fMRI study
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, London, UK
    Cortex 45:517-26. 2009
    ..Neural components of this pathway would be expected to respond to sudden, perhaps unexpected changes in speech signal that result in a change to narrative meaning...
  4. pmc Structural anatomy of pure and hemianopic alexia
    A P Leff
    MRC Clinical Sciences Centre and Division of Neuroscience, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK
    J Neurol Neurosurg Psychiatry 77:1004-7. 2006
    ..Patients with pure alexia also often have a hemianopia but are more disabled, making frequent errors on individual words; they have sustained damage to a brain region that supports efficient word identification...
  5. doi request reprint Treatment of reading impairment after stroke
    Alexander P Leff
    Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, UK
    Curr Opin Neurol 21:644-8. 2008
    ..In this review, we focus on the classification of acquired alexia and the current theory and practice underlying the rehabilitation of this diverse set of disorders...
  6. ncbi request reprint The functional anatomy of single-word reading in patients with hemianopic and pure alexia
    A P Leff
    MRC Clinical Sciences Centre, Cyclotron Unit, Hammersmith Hospital, London W12 0NN, UK
    Brain 124:510-21. 2001
    ..The relative contributions of pure and hemianopic alexia in individual patients needs to be assessed, as the latter has been shown to respond well to specific rehabilitation programmes...
  7. pmc How number processing survives left occipito-temporal damage
    M Cappelletti
    Institute of Cognitive Neuroscience, University College London, London, UK
    Neurocase 18:271-85. 2012
    ....
  8. pmc Changing meaning causes coupling changes within higher levels of the cortical hierarchy
    T M Schofield
    Wellcome Trust Centre for Neuroimaging, University College London, 12 Queen Square, London WC1N 3BG, United Kingdom
    Proc Natl Acad Sci U S A 106:11765-70. 2009
    ..e., a word). Furthermore, our lateralization results suggest left hemisphere specificity for the processing of phonological stimuli, regardless of their elemental (i.e., spectrotemporal) characteristics...
  9. ncbi request reprint Lesion sites that predict the ability to gesture how an object is used
    C J Price
    Wellcome Trust Centre for Neuro imaging, Institute of Neurology, University College London, UK
    Arch Ital Biol 148:243-58. 2010
    ..Our methods provide a framework for future studies aiming to predict the consequences of brain damage...
  10. ncbi request reprint The planning and guiding of reading saccades: a repetitive transcranial magnetic stimulation study
    A P Leff
    Medical Research Council Cyclotron Unit and Imperial College School of Medicine, Hammersmith Hospital, London W12 0NN, UK
    Cereb Cortex 11:918-23. 2001
    ..Our results are compatible with the hypotheses that the left PPC maintains reading saccades along a line of text while the right FEF is involved in the preparation of the motor plan for the scanpath at the start of each new line of text...
  11. pmc Optokinetic therapy improves text reading in patients with hemianopic alexia: a controlled trial
    G A Spitzyna
    Department of Clinical Neurosciences, Royal Free Hospital and University College Medical School, London, UK
    Neurology 68:1922-30. 2007
    ....
  12. doi request reprint Reading Front to Back: MEG Evidence for Early Feedback Effects During Word Recognition
    Z V J Woodhead
    Wellcome Trust Centre for Neuroimaging, University College London, London, UK
    Cereb Cortex 24:817-25. 2014
    ..These findings demonstrate that left inferior frontal activity modulates vOT in the early stages of word processing and provides a mechanistic account of top-down effects during word recognition. ..
  13. doi request reprint The role of the thalamus in amnesia: a tractography, high-resolution MRI and neuropsychological study
    L Cipolotti
    Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
    Neuropsychologia 46:2745-58. 2008
    ..This finding raises the possibility that fractionation of familiarity and recollection to separate thalamic nuclei may not fully capture the role of thalamic sub-regions in memory function...
  14. pmc "Bottom-up" and "top-down" effects on reading saccades: a case study
    N J Upton
    Department of Human Sciences, Brunel University, Uxbridge, Middlesex UB8 2HG, UK
    J Neurol Neurosurg Psychiatry 74:1423-8. 2003
    ..To investigate the role right foveal/parafoveal sparing plays in reading single words, word arrays, and eye movement patterns in a single case with an incongruous hemianopia...