Michael C Lee

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Amygdala activity contributes to the dissociative effect of cannabis on pain perception
    Michael C Lee
    Centre for Functional MRI ofBrain FMRIB, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Pain 154:124-34. 2013
  2. doi request reprint Identifying brain activity specifically related to the maintenance and perceptual consequence of central sensitization in humans
    Michael C Lee
    Department of Clinical Neurology, Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford, United Kingdom
    J Neurosci 28:11642-9. 2008
  3. doi request reprint Flexible cerebral connectivity patterns subserve contextual modulations of pain
    Markus Ploner
    FMRIB Centre and Nuffield Department of Anaesthetics, University of Oxford, Oxford OX3 9DU, UK
    Cereb Cortex 21:719-26. 2011
  4. doi request reprint The effect of treatment expectation on drug efficacy: imaging the analgesic benefit of the opioid remifentanil
    Ulrike Bingel
    Oxford Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences Division of Anaesthetics, University of Oxford, OX3 9DU Oxford, UK
    Sci Transl Med 3:70ra14. 2011
  5. pmc Prestimulus functional connectivity determines pain perception in humans
    Markus Ploner
    Oxford Centre for Functional Magnetic Resonance Imaging of Brain, Department of Clinical Neurology, University of Oxford, UK
    Proc Natl Acad Sci U S A 107:355-60. 2010
  6. pmc The importance of context: when relative relief renders pain pleasant
    Siri Leknes
    Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Pain 154:402-10. 2013
  7. doi request reprint A multisensory investigation of the functional significance of the "pain matrix"
    Andre Mouraux
    Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford, UK
    Neuroimage 54:2237-49. 2011
  8. doi request reprint Stimulus site and modality dependence of functional activity within the human spinal cord
    Jonathan C W Brooks
    Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, Nuffield Division of Anaesthetics, University of Oxford, Oxford OX3 9DU, UK
    J Neurosci 32:6231-9. 2012
  9. pmc Baseline reward circuitry activity and trait reward responsiveness predict expression of opioid analgesia in healthy subjects
    Vishvarani Wanigasekera
    Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, Nuffield Division of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 109:17705-10. 2012
  10. doi request reprint Characterizing the cortical activity through which pain emerges from nociception
    Michael C Lee
    Department of Anaesthesia, University of Cambridge, Cambridge CB2 2QQ, United Kingdom
    J Neurosci 29:7909-16. 2009

Detail Information

Publications10

  1. pmc Amygdala activity contributes to the dissociative effect of cannabis on pain perception
    Michael C Lee
    Centre for Functional MRI ofBrain FMRIB, Department of Clinical Neurology, University of Oxford, Oxford, UK
    Pain 154:124-34. 2013
    ..Instead, the data reveal that amygdala activity contributes to interindividual response to cannabinoid analgesia, and suggest that dissociative effects of THC in the brain are relevant to pain relief in humans...
  2. doi request reprint Identifying brain activity specifically related to the maintenance and perceptual consequence of central sensitization in humans
    Michael C Lee
    Department of Clinical Neurology, Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford, United Kingdom
    J Neurosci 28:11642-9. 2008
    ....
  3. doi request reprint Flexible cerebral connectivity patterns subserve contextual modulations of pain
    Markus Ploner
    FMRIB Centre and Nuffield Department of Anaesthetics, University of Oxford, Oxford OX3 9DU, UK
    Cereb Cortex 21:719-26. 2011
    ....
  4. doi request reprint The effect of treatment expectation on drug efficacy: imaging the analgesic benefit of the opioid remifentanil
    Ulrike Bingel
    Oxford Centre for Functional MRI of the Brain, Nuffield Department of Clinical Neurosciences Division of Anaesthetics, University of Oxford, OX3 9DU Oxford, UK
    Sci Transl Med 3:70ra14. 2011
    ..We propose that it may be necessary to integrate patients' beliefs and expectations into drug treatment regimes alongside traditional considerations in order to optimize treatment outcomes...
  5. pmc Prestimulus functional connectivity determines pain perception in humans
    Markus Ploner
    Oxford Centre for Functional Magnetic Resonance Imaging of Brain, Department of Clinical Neurology, University of Oxford, UK
    Proc Natl Acad Sci U S A 107:355-60. 2010
    ..We conclude that variations in functional connectivity underlie personality-related differences in individual susceptibility to pain...
  6. pmc The importance of context: when relative relief renders pain pleasant
    Siri Leknes
    Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences Nuffield Division of Anaesthetics, University of Oxford, Oxford, UK
    Pain 154:402-10. 2013
    ..The findings of this study point to a role for brainstem and reward circuitry in a context-induced "hedonic flip" of pain...
  7. doi request reprint A multisensory investigation of the functional significance of the "pain matrix"
    Andre Mouraux
    Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, Oxford, UK
    Neuroimage 54:2237-49. 2011
    ..Taken together, these findings suggest that the largest part of the fMRI responses elicited by phasic nociceptive stimuli reflects non nociceptive-specific cognitive processes...
  8. doi request reprint Stimulus site and modality dependence of functional activity within the human spinal cord
    Jonathan C W Brooks
    Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, Nuffield Division of Anaesthetics, University of Oxford, Oxford OX3 9DU, UK
    J Neurosci 32:6231-9. 2012
    ..The development of these techniques opens the path to understanding, at a subject-specific level, central sensitization processes that contribute to chronic pain states...
  9. pmc Baseline reward circuitry activity and trait reward responsiveness predict expression of opioid analgesia in healthy subjects
    Vishvarani Wanigasekera
    Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, Nuffield Division of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom
    Proc Natl Acad Sci U S A 109:17705-10. 2012
    ..These results support the notion of future imaging-based subject-stratification paradigms that can guide therapeutic decisions...
  10. doi request reprint Characterizing the cortical activity through which pain emerges from nociception
    Michael C Lee
    Department of Anaesthesia, University of Cambridge, Cambridge CB2 2QQ, United Kingdom
    J Neurosci 29:7909-16. 2009
    ....