Jonathan L C Lee

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Conditioned suppression and freezing as measures of aversive Pavlovian conditioning: effects of discrete amygdala lesions and overtraining
    Jonathan L C Lee
    Department of Experimental Psychology, MRC Centre for Behavioural and Clinical Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Behav Brain Res 159:221-33. 2005
  2. ncbi request reprint Disrupting reconsolidation of drug memories reduces cocaine-seeking behavior
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, United Kingdom
    Neuron 47:795-801. 2005
  3. ncbi request reprint Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 26:5881-7. 2006
  4. ncbi request reprint Reconsolidation and extinction of conditioned fear: inhibition and potentiation
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 26:10051-6. 2006
  5. doi request reprint Reactivation-dependent amnesia for appetitive memories is determined by the contingency of stimulus presentation
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:390-3. 2008
  6. doi request reprint Appetitive memory reconsolidation depends upon NMDA receptor-mediated neurotransmission
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Neurobiol Learn Mem 90:147-54. 2008
  7. pmc The basolateral amygdala and nucleus accumbens core mediate dissociable aspects of drug memory reconsolidation
    Florence R M Theberge
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Learn Mem 17:444-53. 2010
  8. pmc D-cycloserine potentiates the reconsolidation of cocaine-associated memories
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, United Kingdom
    Learn Mem 16:82-5. 2009
  9. doi request reprint Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors
    Amy L Milton
    Department of Experimental Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge CB2 3EB, United Kingdom
    J Neurosci 28:8230-7. 2008
  10. pmc Reactivation-dependent amnesia in Pavlovian approach and instrumental transfer
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:597-602. 2008

Detail Information

Publications13

  1. ncbi request reprint Conditioned suppression and freezing as measures of aversive Pavlovian conditioning: effects of discrete amygdala lesions and overtraining
    Jonathan L C Lee
    Department of Experimental Psychology, MRC Centre for Behavioural and Clinical Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Behav Brain Res 159:221-33. 2005
    ....
  2. ncbi request reprint Disrupting reconsolidation of drug memories reduces cocaine-seeking behavior
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, United Kingdom
    Neuron 47:795-801. 2005
    ....
  3. ncbi request reprint Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 26:5881-7. 2006
    ..Reconsolidation blockade may thus provide a potential therapeutic strategy for the prevention of relapse in drug addiction...
  4. ncbi request reprint Reconsolidation and extinction of conditioned fear: inhibition and potentiation
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 26:10051-6. 2006
    ..These results have important implications for the use of reconsolidation blockade and potentiation of extinction as treatment strategies for maladaptive memory disorders...
  5. doi request reprint Reactivation-dependent amnesia for appetitive memories is determined by the contingency of stimulus presentation
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:390-3. 2008
    ..These results have important implications for the potential translational use of glutamatergic treatments in conjunction with targeted memory reactivation...
  6. doi request reprint Appetitive memory reconsolidation depends upon NMDA receptor-mediated neurotransmission
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Neurobiol Learn Mem 90:147-54. 2008
    ..These results demonstrate that NMDA receptor-mediated signaling is required for appetitive pavlovian memory reconsolidation...
  7. pmc The basolateral amygdala and nucleus accumbens core mediate dissociable aspects of drug memory reconsolidation
    Florence R M Theberge
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Learn Mem 17:444-53. 2010
    ..However reconsolidation of memory representations formed during Pavlovian conditioning are differentially localized in each site...
  8. pmc D-cycloserine potentiates the reconsolidation of cocaine-associated memories
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, United Kingdom
    Learn Mem 16:82-5. 2009
    ..This elevation of cocaine seeking was correlated with an increase in the expression of the reconsolidation-associated gene zif268...
  9. doi request reprint Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors
    Amy L Milton
    Department of Experimental Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge CB2 3EB, United Kingdom
    J Neurosci 28:8230-7. 2008
    ..These data suggest that drugs modulating glutamatergic transmission at the NMDA receptor may be useful in the future treatment of relapse prevention in drug addiction through memory reconsolidation blockade...
  10. pmc Reactivation-dependent amnesia in Pavlovian approach and instrumental transfer
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:597-602. 2008
    ....
  11. doi request reprint Reconsolidation of appetitive memories for both natural and drug reinforcement is dependent on {beta}-adrenergic receptors
    Amy L Milton
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Downing Site, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:88-92. 2008
    ....
  12. ncbi request reprint Independent cellular processes for hippocampal memory consolidation and reconsolidation
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Science 304:839-43. 2004
    ..These findings confirm a requirement for BDNF specifically in memory consolidation and also resolve the role of Zif268 in brain plasticity, learning, and memory...
  13. ncbi request reprint Disrupting reconsolidation of conditioned withdrawal memories in the basolateral amygdala reduces suppression of heroin seeking in rats
    Kim G C Hellemans
    Department of Experimental Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
    J Neurosci 26:12694-9. 2006
    ..These results demonstrate that drug withdrawal memories undergo protein synthesis-dependent reconsolidation in the BLA and suggest a common mechanism for the reconsolidation of both appetitive and aversive drug memories...