Jonathan L C Lee

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. pmc Behavioural memory reconsolidation of food and fear memories
    Charlotte R Flavell
    University of Birmingham, School of Psychology, Edgbaston, Birmingham B15 2TT, UK
    Nat Commun 2:504. 2011
  2. pmc Memory reconsolidation mediates the updating of hippocampal memory content
    Jonathan L C Lee
    School of Psychology, University of Birmingham Birmingham, UK
    Front Behav Neurosci 4:168. 2010
  3. pmc How to erase memory traces of pain and fear
    Jürgen Sandkühler
    Department of Neurophysiology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, A 1090 Vienna, Austria
    Trends Neurosci 36:343-52. 2013
  4. pmc Divergent cellular pathways of hippocampal memory consolidation and reconsolidation
    Jonathan L C Lee
    School of Psychology, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    Hippocampus 23:233-44. 2013
  5. pmc D-cycloserine potentiates the reconsolidation of cocaine-associated memories
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, United Kingdom
    Learn Mem 16:82-5. 2009
  6. pmc Reconsolidation: maintaining memory relevance
    Jonathan L C Lee
    School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Trends Neurosci 32:413-20. 2009
  7. doi request reprint Memory reconsolidation mediates the strengthening of memories by additional learning
    Jonathan L C Lee
    School of Psychology, University of Birmingham, Edgbaston, Birmingham, UK
    Nat Neurosci 11:1264-6. 2008
  8. doi request reprint Reactivation-dependent amnesia for appetitive memories is determined by the contingency of stimulus presentation
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:390-3. 2008
  9. ncbi request reprint Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors
    Amy L Milton
    Department of Experimental Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge CB2 3EB, United Kingdom
    J Neurosci 28:8230-7. 2008
  10. pmc The basolateral amygdala and nucleus accumbens core mediate dissociable aspects of drug memory reconsolidation
    Florence R M Theberge
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Learn Mem 17:444-53. 2010

Collaborators

Detail Information

Publications24

  1. pmc Behavioural memory reconsolidation of food and fear memories
    Charlotte R Flavell
    University of Birmingham, School of Psychology, Edgbaston, Birmingham B15 2TT, UK
    Nat Commun 2:504. 2011
    ..Therefore, the reconsolidation process can be manipulated behaviourally to disrupt both aversive and appetitive memories...
  2. pmc Memory reconsolidation mediates the updating of hippocampal memory content
    Jonathan L C Lee
    School of Psychology, University of Birmingham Birmingham, UK
    Front Behav Neurosci 4:168. 2010
    ..Therefore, an adaptive function of the reactivation and reconsolidation process is to enable the updating of memory content...
  3. pmc How to erase memory traces of pain and fear
    Jürgen Sandkühler
    Department of Neurophysiology, Center for Brain Research, Medical University of Vienna, Spitalgasse 4, A 1090 Vienna, Austria
    Trends Neurosci 36:343-52. 2013
    ..Thus, the processes of erasing memory traces of pain and fear may constitute promising targets for future therapies...
  4. pmc Divergent cellular pathways of hippocampal memory consolidation and reconsolidation
    Jonathan L C Lee
    School of Psychology, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    Hippocampus 23:233-44. 2013
    ..Therefore, there are divergent pathways of hippocampal memory consolidation and reconsolidation, involving commonality at the cell surface, but separable downstream kinase cascades and transcriptional regulation...
  5. pmc D-cycloserine potentiates the reconsolidation of cocaine-associated memories
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, United Kingdom
    Learn Mem 16:82-5. 2009
    ..This elevation of cocaine seeking was correlated with an increase in the expression of the reconsolidation-associated gene zif268...
  6. pmc Reconsolidation: maintaining memory relevance
    Jonathan L C Lee
    School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Trends Neurosci 32:413-20. 2009
    ..Here, the adaptive function of memory reconsolidation is explored in more detail, with a strong emphasis on its role in updating memories to maintain their relevance...
  7. doi request reprint Memory reconsolidation mediates the strengthening of memories by additional learning
    Jonathan L C Lee
    School of Psychology, University of Birmingham, Edgbaston, Birmingham, UK
    Nat Neurosci 11:1264-6. 2008
    ..I found that one normal function of hippocampal memory reconsolidation in rats is to modify the strength of a contextual-fear memory as a result of further learning...
  8. doi request reprint Reactivation-dependent amnesia for appetitive memories is determined by the contingency of stimulus presentation
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:390-3. 2008
    ..These results have important implications for the potential translational use of glutamatergic treatments in conjunction with targeted memory reactivation...
  9. ncbi request reprint Intra-amygdala and systemic antagonism of NMDA receptors prevents the reconsolidation of drug-associated memory and impairs subsequently both novel and previously acquired drug-seeking behaviors
    Amy L Milton
    Department of Experimental Psychology, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Site, Cambridge CB2 3EB, United Kingdom
    J Neurosci 28:8230-7. 2008
    ..These data suggest that drugs modulating glutamatergic transmission at the NMDA receptor may be useful in the future treatment of relapse prevention in drug addiction through memory reconsolidation blockade...
  10. pmc The basolateral amygdala and nucleus accumbens core mediate dissociable aspects of drug memory reconsolidation
    Florence R M Theberge
    Department of Experimental Psychology, University of Cambridge, Cambridge, United Kingdom
    Learn Mem 17:444-53. 2010
    ..However reconsolidation of memory representations formed during Pavlovian conditioning are differentially localized in each site...
  11. ncbi request reprint Disrupting reconsolidation of drug memories reduces cocaine-seeking behavior
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, United Kingdom
    Neuron 47:795-801. 2005
    ....
  12. pmc Reactivation-dependent amnesia in Pavlovian approach and instrumental transfer
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:597-602. 2008
    ....
  13. ncbi request reprint Appetitive memory reconsolidation depends upon NMDA receptor-mediated neurotransmission
    Jonathan L C Lee
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Neurobiol Learn Mem 90:147-54. 2008
    ..These results demonstrate that NMDA receptor-mediated signaling is required for appetitive pavlovian memory reconsolidation...
  14. doi request reprint Post-training unilateral amygdala lesions selectively impair contextual fear memories
    Charlotte R Flavell
    University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
    Learn Mem 19:256-63. 2012
    ..Therefore, post-training unilateral lesions of the BLA are sufficient to severely impair contextual, but not cued, fear memories...
  15. ncbi request reprint Reconsolidation and extinction of conditioned fear: inhibition and potentiation
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 26:10051-6. 2006
    ..These results have important implications for the use of reconsolidation blockade and potentiation of extinction as treatment strategies for maladaptive memory disorders...
  16. ncbi request reprint Independent cellular processes for hippocampal memory consolidation and reconsolidation
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Science 304:839-43. 2004
    ..These findings confirm a requirement for BDNF specifically in memory consolidation and also resolve the role of Zif268 in brain plasticity, learning, and memory...
  17. doi request reprint Reconsolidation of appetitive memories for both natural and drug reinforcement is dependent on {beta}-adrenergic receptors
    Amy L Milton
    Behavioural and Clinical Neuroscience Institute, Department of Experimental Psychology, University of Cambridge, Downing Site, Cambridge CB2 3EB, United Kingdom
    Learn Mem 15:88-92. 2008
    ....
  18. ncbi request reprint Cue-induced cocaine seeking and relapse are reduced by disruption of drug memory reconsolidation
    Jonathan L C Lee
    Department of Experimental Psychology, University of Cambridge, Cambridge CB2 3EB, United Kingdom
    J Neurosci 26:5881-7. 2006
    ..Reconsolidation blockade may thus provide a potential therapeutic strategy for the prevention of relapse in drug addiction...
  19. ncbi request reprint Conditioned suppression and freezing as measures of aversive Pavlovian conditioning: effects of discrete amygdala lesions and overtraining
    Jonathan L C Lee
    Department of Experimental Psychology, MRC Centre for Behavioural and Clinical Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK
    Behav Brain Res 159:221-33. 2005
    ....
  20. doi request reprint Reconsolidation and extinction of an appetitive pavlovian memory
    Charlotte R Flavell
    University of Birmingham, UK
    Neurobiol Learn Mem 104:25-31. 2013
    ..These results demonstrate a competition between reconsolidation and extinction. However, there are also conditions under which MK-801 fails to impair either process...
  21. doi request reprint Over-expectation generated in a complex appetitive goal-tracking task is capable of inducing memory reconsolidation
    Amy C Reichelt
    School of Psychology, University of Birmingham, Edgbaston, Birmingham, B15 3JX, UK
    Psychopharmacology (Berl) 226:649-58. 2013
    ..Discrepancies in an expected outcome have been demonstrated to result in modification of behaviour in both appetitive and aversive conditioning settings...
  22. doi request reprint Ventral tegmental dopamine dysregulation prevents appetitive memory destabilization
    Amy C Reichelt
    School of Psychology, University of Birmingham, Birmingham, B15 2TT, United Kingdom
    J Neurosci 33:14205-10. 2013
    ....
  23. doi request reprint Appetitive Pavlovian goal-tracking memories reconsolidate only under specific conditions
    Amy C Reichelt
    School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
    Learn Mem 20:51-60. 2012
    ..Moreover, extinction per se is not a boundary on reconsolidation, in that MK-801 also has no behavioral effect under some conditions...
  24. ncbi request reprint Disrupting reconsolidation of conditioned withdrawal memories in the basolateral amygdala reduces suppression of heroin seeking in rats
    Kim G C Hellemans
    Department of Experimental Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom
    J Neurosci 26:12694-9. 2006
    ..These results demonstrate that drug withdrawal memories undergo protein synthesis-dependent reconsolidation in the BLA and suggest a common mechanism for the reconsolidation of both appetitive and aversive drug memories...