Mike Lean

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. pmc Influence of polymorphisms in the RANKL/RANK/OPG signaling pathway on volumetric bone mineral density and bone geometry at the forearm in men
    Delnaz Roshandel
    Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Stopford Building, UK
    Calcif Tissue Int 89:446-55. 2011
  2. pmc A validation of the first genome-wide association study of calcaneus ultrasound parameters in the European Male Ageing Study
    Delnaz Roshandel
    Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
    BMC Med Genet 12:19. 2011
  3. ncbi request reprint Dietary flavonols protect diabetic human lymphocytes against oxidative damage to DNA
    M E Lean
    Department of Human Nutrition, Glasgow Royal Infirmary, University of Glasgow, UK
    Diabetes 48:176-81. 1999
  4. ncbi request reprint Is long-term weight loss possible?
    M E Lean
    Department of Human Nutrition, University of Glasgow
    Br J Nutr 83:S103-11. 2000
  5. ncbi request reprint Pathophysiology of obesity
    M E Lean
    Department of Human Nutrition, University of Glasgow, Glasgow Royal Infirmary, UK
    Proc Nutr Soc 59:331-6. 2000
  6. ncbi request reprint Patients on atypical antipsychotic drugs: another high-risk group for type 2 diabetes
    Michael E J Lean
    Department of Human Nutrition, University of Glasgow, UK
    Diabetes Care 26:1597-605. 2003
  7. ncbi request reprint Schizophrenia and osteoporosis
    Mike Lean
    Department of Human Nutrition, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Int Clin Psychopharmacol 19:31-5. 2004
  8. ncbi request reprint Smoking combined with overweight or obesity markedly elevates cardiovascular risk factors
    Mehdi Akbartabartoori
    Human Nutrition at Glasgow, Division of Developmental Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, Scotland, UK
    Eur J Cardiovasc Prev Rehabil 13:938-46. 2006
  9. doi request reprint Contribution of Midparental BMI and other determinants of obesity in adult offspring
    Niveen M E Abu-Rmeileh
    General Practice and Primary Care, Division of Community Based Sciences, University of Glasgow, Glasgow, UK
    Obesity (Silver Spring) 16:1388-93. 2008
  10. doi request reprint Intergenerational change and familial aggregation of body mass index
    Paul C D Johnson
    Robertson Centre for Biostatistics, Boyd Orr Building, University of Glasgow, Glasgow, UK
    Eur J Epidemiol 27:53-61. 2012

Collaborators

  • Von F G Pajonk
  • Preethi Koshy
  • Naveed Sattar
  • Mhairi Mackenzie
  • Jennifer Logue
  • Alex McConnachie
  • Frank Gerald Pajonk
  • A Crozier
  • Mehdi Akbartabartoori
  • M N Upton
  • Carole L Hart
  • K J Hunt
  • S Haffner
  • Thang S Han
  • Delnaz Roshandel
  • Niveen M E Abu-Rmeileh
  • Paul C D Johnson
  • Frederick C Wu
  • Neil Pendleton
  • Stephen R Pye
  • Wendy Thomson
  • Aleksander Giwercman
  • Herman Borghs
  • Joseph D Finn
  • Kate A Ward
  • Dirk Vanderschueren
  • Judith E Adams
  • Krzysztof Kula
  • Alan J Silman
  • Kate L Holliday
  • Gyorgy Bartfai
  • Ilpo T Huhtaniemi
  • Margus Punab
  • Gianni Forti
  • Steven Boonen
  • Gina Borges
  • Ken Williams
  • Graham Watt
  • David Lee
  • Philip Steer
  • Alan Silman
  • Imre Földesi
  • Felipe Casanueva
  • Min Jiang
  • Paul Korrovitz
  • Joseph Finn
  • Mary Lage
  • Luisa Petrone
  • Terence W ONeill
  • Terence W O'Neill
  • Stephen Pye
  • Frederick Wu
  • Jolanta Slowikowska-Hilczer
  • Ilpo Huhtaniemi
  • Imre Fejes
  • Felipe F Casanueva
  • Terence O'Neill
  • Glovanni Corona
  • Renata Walczak-Jedrzejowska
  • Abdelouahid Tajar
  • Susan A Roberts
  • Adam Mullan
  • William Mullen
  • Graham C M Watt
  • Clicerio Gonzalez-Villalpando

Detail Information

Publications14

  1. pmc Influence of polymorphisms in the RANKL/RANK/OPG signaling pathway on volumetric bone mineral density and bone geometry at the forearm in men
    Delnaz Roshandel
    Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Stopford Building, UK
    Calcif Tissue Int 89:446-55. 2011
    ..90 [0.92-16.88], P = 0.029). No significant association was observed between RANKL SNPs and pQCT parameters. Our findings suggest that genetic variation in OPG and RANK influences radius vBMD and geometry in men...
  2. pmc A validation of the first genome-wide association study of calcaneus ultrasound parameters in the European Male Ageing Study
    Delnaz Roshandel
    Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
    BMC Med Genet 12:19. 2011
    ..The association between these SNPs and bone mineral density (BMD) measured using dual-energy X-ray absorptiometry (DXA) was also tested...
  3. ncbi request reprint Dietary flavonols protect diabetic human lymphocytes against oxidative damage to DNA
    M E Lean
    Department of Human Nutrition, Glasgow Royal Infirmary, University of Glasgow, UK
    Diabetes 48:176-81. 1999
    ..In conclusion, we have shown a biological effect of potential medical importance that appears to be associated with the absorption of dietary flavonols...
  4. ncbi request reprint Is long-term weight loss possible?
    M E Lean
    Department of Human Nutrition, University of Glasgow
    Br J Nutr 83:S103-11. 2000
    ..In routine clinical practice, treatments are changed in the light of early experience as a therapeutic trial to optimize the results for each individual, and audit is required to evaluate 'long term weight loss'...
  5. ncbi request reprint Pathophysiology of obesity
    M E Lean
    Department of Human Nutrition, University of Glasgow, Glasgow Royal Infirmary, UK
    Proc Nutr Soc 59:331-6. 2000
    ..The greatest challenge for public health is to develop effective preventive measures, recognizing that BMI > 25 kg/m2 before the age of 20 years is a very strong predictor of obesity and ill health in adulthood...
  6. ncbi request reprint Patients on atypical antipsychotic drugs: another high-risk group for type 2 diabetes
    Michael E J Lean
    Department of Human Nutrition, University of Glasgow, UK
    Diabetes Care 26:1597-605. 2003
    ..This collaboration will also help minimize the already high risk of cardiovascular disease in individuals with schizophrenia...
  7. ncbi request reprint Schizophrenia and osteoporosis
    Mike Lean
    Department of Human Nutrition, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Int Clin Psychopharmacol 19:31-5. 2004
    ..The uncertainty over this issue underlines the need for full medical and metabolic assessment and monitoring of psychiatric patients...
  8. ncbi request reprint Smoking combined with overweight or obesity markedly elevates cardiovascular risk factors
    Mehdi Akbartabartoori
    Human Nutrition at Glasgow, Division of Developmental Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, Scotland, UK
    Eur J Cardiovasc Prev Rehabil 13:938-46. 2006
    ..We examined the impacts of smoking, overweight and obesity on cardiovascular risk factors: total cholesterol, high-density lipoprotein (HDL)-cholesterol, non-HDL-cholesterol, C-reactive protein and fibrinogen...
  9. doi request reprint Contribution of Midparental BMI and other determinants of obesity in adult offspring
    Niveen M E Abu-Rmeileh
    General Practice and Primary Care, Division of Community Based Sciences, University of Glasgow, Glasgow, UK
    Obesity (Silver Spring) 16:1388-93. 2008
    ..Whether it represents genetic or environmental family effects, it is easily ascertained by the individual and could be used in health promotion and clinical settings to target individuals who are at increased risk of becoming obese...
  10. doi request reprint Intergenerational change and familial aggregation of body mass index
    Paul C D Johnson
    Robertson Centre for Biostatistics, Boyd Orr Building, University of Glasgow, Glasgow, UK
    Eur J Epidemiol 27:53-61. 2012
    ..Familial influences on BMI among middle-aged women appear significantly stronger from mothers than fathers...
  11. pmc Eating the elephant whole or in slices: views of participants in a smoking cessation intervention trial on multiple behaviour changes as sequential or concurrent tasks
    Preethi Koshy
    Human Nutrition, School of Medicine, University of Glasgow, Glasgow, G4 0SF, UK
    BMC Public Health 12:500. 2012
    ..This paper explores smoking cessation participants' perceptions of attempting weight management alongside smoking cessation within the context of a health improvement intervention implemented in Glasgow, Scotland...
  12. doi request reprint Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drink
    Gina Borges
    Division of Developmental Medicine, Faculty of Medicine, University of Glasgow, Glasgow, UK
    Mol Nutr Food Res 54:S268-77. 2010
    ..It is concluded that the P-R beverage can deliver the intended blend of bioavailable polyphenols, which would normally require consumption of several different plant-derived foods...
  13. ncbi request reprint Analysis of obesity and hyperinsulinemia in the development of metabolic syndrome: San Antonio Heart Study
    Thang S Han
    Cambridge Clinical School, Cambridge, United Kingdom
    Obes Res 10:923-31. 2002
    ..To use standardized cut-offs of body mass index (BMI), waist circumference, waist-to-hip ratio, and fasting insulin levels to predict the development of metabolic disorders and metabolic syndrome...
  14. ncbi request reprint Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study
    Thang S Han
    Addenbrooke s Hospital, Cambridge University Medical School, Cambridge, U K
    Diabetes Care 25:2016-21. 2002
    ..We evaluated CRP as a possible risk factor of the development of diabetes and metabolic syndrome in a 6-year study of 515 men and 729 women from the Mexico City Diabetes Study...