Affiliation: University of Glasgow
- Influence of polymorphisms in the RANKL/RANK/OPG signaling pathway on volumetric bone mineral density and bone geometry at the forearm in menDelnaz Roshandel
Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Stopford Building, UK
Calcif Tissue Int 89:446-55. 2011..90 [0.92-16.88], P = 0.029). No significant association was observed between RANKL SNPs and pQCT parameters. Our findings suggest that genetic variation in OPG and RANK influences radius vBMD and geometry in men...
- A validation of the first genome-wide association study of calcaneus ultrasound parameters in the European Male Ageing StudyDelnaz Roshandel
Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
BMC Med Genet 12:19. 2011..The association between these SNPs and bone mineral density (BMD) measured using dual-energy X-ray absorptiometry (DXA) was also tested...
- Dietary flavonols protect diabetic human lymphocytes against oxidative damage to DNAM E Lean
Department of Human Nutrition, Glasgow Royal Infirmary, University of Glasgow, UK
Diabetes 48:176-81. 1999..In conclusion, we have shown a biological effect of potential medical importance that appears to be associated with the absorption of dietary flavonols...
- Is long-term weight loss possible?M E Lean
Department of Human Nutrition, University of Glasgow
Br J Nutr 83:S103-11. 2000..In routine clinical practice, treatments are changed in the light of early experience as a therapeutic trial to optimize the results for each individual, and audit is required to evaluate 'long term weight loss'...
- Pathophysiology of obesityM E Lean
Department of Human Nutrition, University of Glasgow, Glasgow Royal Infirmary, UK
Proc Nutr Soc 59:331-6. 2000..The greatest challenge for public health is to develop effective preventive measures, recognizing that BMI > 25 kg/m2 before the age of 20 years is a very strong predictor of obesity and ill health in adulthood...
- Patients on atypical antipsychotic drugs: another high-risk group for type 2 diabetesMichael E J Lean
Department of Human Nutrition, University of Glasgow, UK
Diabetes Care 26:1597-605. 2003..This collaboration will also help minimize the already high risk of cardiovascular disease in individuals with schizophrenia...
- Schizophrenia and osteoporosisMike Lean
Department of Human Nutrition, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
Int Clin Psychopharmacol 19:31-5. 2004..The uncertainty over this issue underlines the need for full medical and metabolic assessment and monitoring of psychiatric patients...
- Smoking combined with overweight or obesity markedly elevates cardiovascular risk factorsMehdi Akbartabartoori
Human Nutrition at Glasgow, Division of Developmental Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, Scotland, UK
Eur J Cardiovasc Prev Rehabil 13:938-46. 2006..We examined the impacts of smoking, overweight and obesity on cardiovascular risk factors: total cholesterol, high-density lipoprotein (HDL)-cholesterol, non-HDL-cholesterol, C-reactive protein and fibrinogen...
- Contribution of Midparental BMI and other determinants of obesity in adult offspringNiveen M E Abu-Rmeileh
General Practice and Primary Care, Division of Community Based Sciences, University of Glasgow, Glasgow, UK
Obesity (Silver Spring) 16:1388-93. 2008..Whether it represents genetic or environmental family effects, it is easily ascertained by the individual and could be used in health promotion and clinical settings to target individuals who are at increased risk of becoming obese...
- Intergenerational change and familial aggregation of body mass indexPaul C D Johnson
Robertson Centre for Biostatistics, Boyd Orr Building, University of Glasgow, Glasgow, UK
Eur J Epidemiol 27:53-61. 2012..Familial influences on BMI among middle-aged women appear significantly stronger from mothers than fathers...
- Eating the elephant whole or in slices: views of participants in a smoking cessation intervention trial on multiple behaviour changes as sequential or concurrent tasksPreethi Koshy
Human Nutrition, School of Medicine, University of Glasgow, Glasgow, G4 0SF, UK
BMC Public Health 12:500. 2012..This paper explores smoking cessation participants' perceptions of attempting weight management alongside smoking cessation within the context of a health improvement intervention implemented in Glasgow, Scotland...
- Bioavailability of multiple components following acute ingestion of a polyphenol-rich juice drinkGina Borges
Division of Developmental Medicine, Faculty of Medicine, University of Glasgow, Glasgow, UK
Mol Nutr Food Res 54:S268-77. 2010..It is concluded that the P-R beverage can deliver the intended blend of bioavailable polyphenols, which would normally require consumption of several different plant-derived foods...
- Analysis of obesity and hyperinsulinemia in the development of metabolic syndrome: San Antonio Heart StudyThang S Han
Cambridge Clinical School, Cambridge, United Kingdom
Obes Res 10:923-31. 2002..Adjustment for baseline fasting insulin levels had only a small effect on the ability of anthropometric indices to predict the metabolic syndrome...
- Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes StudyThang S Han
Addenbrooke's Hospital, Cambridge University Medical School, Cambridge, U.K
Diabetes Care 25:2016-21. 2002..CONCLUSIONS: CRP was not a significant predictor of the development of the metabolic syndrome in men. Our data strongly support the notion that inflammation is important in the pathogenesis of diabetes and metabolic disorders in women...