Charles Henderson Lawrie

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Ixodid and argasid tick species and west nile virus
    Charles Henderson Lawrie
    Centre for Ecology and Hydrology, Oxford, United Kingdom
    Emerg Infect Dis 10:653-7. 2004
  2. ncbi request reprint MicroRNA expression distinguishes between germinal center B cell-like and activated B cell-like subtypes of diffuse large B cell lymphoma
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Int J Cancer 121:1156-61. 2007
  3. doi request reprint MicroRNA expression in lymphoid malignancies: new hope for diagnosis and therapy?
    Charles Henderson Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    J Cell Mol Med 12:1432-44. 2008
  4. doi request reprint MicroRNAs in hematological malignancies
    Charles H Lawrie
    Biodonostia Research Institute, San Sebastian, Spain
    Blood Rev 27:143-54. 2013
  5. doi request reprint Inter- and intra-observational variability in immunohistochemistry: a multicentre analysis of diffuse large B-cell lymphoma staining
    Charles H Lawrie
    Biodonostia Research Institute, San Sebastian, and IKERBASQUE, Basque Foundation for Science, Bilbao, Spain
    Histopathology 61:18-25. 2012
  6. pmc MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival
    Jianxiang Chi
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, UK
    Biol Direct 6:23. 2011
  7. doi request reprint microRNA expression in erythropoiesis and erythroid disorders
    Charles H Lawrie
    Lymphoid Malignancy Research Group, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 150:144-51. 2010
  8. doi request reprint Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    J Cell Mol Med 13:1248-60. 2009
  9. doi request reprint Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 141:672-5. 2008
  10. ncbi request reprint MicroRNA expression in lymphoma
    Charles H Lawrie
    University of Oxford, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Expert Opin Biol Ther 7:1363-74. 2007

Collaborators

Detail Information

Publications19

  1. pmc Ixodid and argasid tick species and west nile virus
    Charles Henderson Lawrie
    Centre for Ecology and Hydrology, Oxford, United Kingdom
    Emerg Infect Dis 10:653-7. 2004
    ..moubata ticks co-fed upon uninfected hosts. Although ticks are unlikely to play a major role in WNV transmission, our findings suggest that some species have the potential to act as reservoirs for the virus...
  2. ncbi request reprint MicroRNA expression distinguishes between germinal center B cell-like and activated B cell-like subtypes of diffuse large B cell lymphoma
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Int J Cancer 121:1156-61. 2007
    ..001), we suggest that microRNAs could be clinically useful molecular markers for DLBCL as well as other cancers...
  3. doi request reprint MicroRNA expression in lymphoid malignancies: new hope for diagnosis and therapy?
    Charles Henderson Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    J Cell Mol Med 12:1432-44. 2008
    ....
  4. doi request reprint MicroRNAs in hematological malignancies
    Charles H Lawrie
    Biodonostia Research Institute, San Sebastian, Spain
    Blood Rev 27:143-54. 2013
    ..Although still in its infancy, the miRNA field has already added much to our understanding of hematological processes, and provides us with novel tools as both biomarkers and therapeutic agents for hematological malignancies...
  5. doi request reprint Inter- and intra-observational variability in immunohistochemistry: a multicentre analysis of diffuse large B-cell lymphoma staining
    Charles H Lawrie
    Biodonostia Research Institute, San Sebastian, and IKERBASQUE, Basque Foundation for Science, Bilbao, Spain
    Histopathology 61:18-25. 2012
    ..However, despite the obvious need to address such variability, very few studies have done so...
  6. pmc MicroRNA expression in multiple myeloma is associated with genetic subtype, isotype and survival
    Jianxiang Chi
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, UK
    Biol Direct 6:23. 2011
    ..0) of purified tumor (CD138+) cells from 33 patients with MM, 5 patients with monoclonal gammopathy of undetermined significance (MGUS) and 9 controls...
  7. doi request reprint microRNA expression in erythropoiesis and erythroid disorders
    Charles H Lawrie
    Lymphoid Malignancy Research Group, Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 150:144-51. 2010
    ..In this review the rapidly accumulating evidence that points to the major role microRNAs play in both erythropoiesis and erythroid disorders is discussed...
  8. doi request reprint Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    J Cell Mol Med 13:1248-60. 2009
    ..05). These data suggest that microRNAs have potential as diagnostic and prognostic markers in these lymphomas and may be used to identify FCL patients at risk of high-grade transformation...
  9. doi request reprint Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 141:672-5. 2008
    ..05). This is the first description of circulating microRNAs and suggests that microRNAs have potential as non-invasive diagnostic markers for DLBCL and possibly other cancers...
  10. ncbi request reprint MicroRNA expression in lymphoma
    Charles H Lawrie
    University of Oxford, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Expert Opin Biol Ther 7:1363-74. 2007
    ..In this review the authors discuss the rapidly accumulating evidence for the central role that microRNAs play in both haematopoiesis and haematological malignancy, in particular focusing on their role in lymphoma...
  11. ncbi request reprint Susceptibility of mosquito and tick cell lines to infection with various flaviviruses
    C H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, UK
    Med Vet Entomol 18:268-74. 2004
    ....
  12. ncbi request reprint MicroRNAs and haematology: small molecules, big function
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 137:503-12. 2007
    ..g. MIRN155 (miR-155) and MIRN17-92 (miR-17-miR-92) cluster] in lymphomas. This review discusses the rapidly accumulating research that points to the major role microRNAs play in both haematopoiesis and haematological malignancy...
  13. ncbi request reprint Cancer-associated carbohydrate identification in Hodgkin's lymphoma by carbohydrate array profiling
    Charles H Lawrie
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, UK
    Int J Cancer 118:3161-6. 2006
    ..271). We suggest that this technique could provide a powerful tool for identifying novel carbohydrates in other cancers...
  14. ncbi request reprint Investigation of the mechanisms of anti-complement activity in Ixodes ricinus ticks
    Charles H Lawrie
    LRF Immunodiagnostics Unit, Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Level 5, Academic Block, University of Oxford, Oxford OX3 9DU, UK
    Mol Immunol 42:31-8. 2005
    ..The activity was specific for the alpha-chain of C3 but not of C3(H2O) nor the alpha'-chain of C3b. It is proposed that SGE-modified C3 does not participate in convertase formation, probably having a reduced affinity for factor B...
  15. pmc MicroRNA expression in Sezary syndrome: identification, function, and diagnostic potential
    Erica Ballabio
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Blood 116:1105-13. 2010
    ..We also provide the first in vivo evidence for down-regulation of the miR-17-92 cluster in malignancy and demonstrate that ectopic miR-17-5p expression increases apoptosis and decreases cell proliferation in SzS cells...
  16. pmc CD4-positive T-helper cell responses to the PASD1 protein in patients with diffuse large B-cell lymphoma
    Kamel Ait-Tahar
    Nuffield Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK
    Haematologica 96:78-86. 2011
    ....
  17. ncbi request reprint Gene expression profiling of CD34+ cells in patients with the 5q- syndrome
    Jacqueline Boultwood
    LRF Molecular Haematology Unit, NDCLS, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 139:578-89. 2007
    ..This study suggests that several of the genes mapping to the CDR of the 5q- syndrome play a role in the pathogenesis of this disorder...
  18. ncbi request reprint MORC4, a novel member of the MORC family, is highly expressed in a subset of diffuse large B-cell lymphomas
    Amanda P Liggins
    LRF Lymphoma Antigens Group, John Radcliffe Hospital, Oxford, Oxfordshire, UK
    Br J Haematol 138:479-86. 2007
    ..0031). The differential expression of MORC4 identifies this molecule as a potential lymphoma biomarker, whose overexpression may contribute to the immunological recognition of MORC4 by a subgroup of DLBCL patients...
  19. doi request reprint Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells
    Andrew J Campbell
    Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Br J Haematol 149:221-30. 2010
    ..FOXP2 represents the first transcription factor whose expression consistently differentiates normal and abnormal plasma cells and FOXP2 target genes are implicated in MM pathogenesis...