J M Lawrence

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Schwann cell grafting into the retina of the dystrophic RCS rat limits functional deterioration. Royal College of Surgeons
    J M Lawrence
    Institute of Ophthalmology, University College London, UK
    Invest Ophthalmol Vis Sci 41:518-28. 2000
  2. ncbi request reprint Transplantation of Schwann cell line clones secreting GDNF or BDNF into the retinas of dystrophic Royal College of Surgeons rats
    Jean M Lawrence
    Department of Pathology, Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 45:267-74. 2004
  3. ncbi request reprint Cell transplantation as a treatment for retinal disease
    R D Lund
    Institute of Ophthalmology, Bath Street, EC1V 9EL, London, UK
    Prog Retin Eye Res 20:415-49. 2001
  4. ncbi request reprint Progressive visual sensitivity loss in the Royal College of Surgeons rat: perimetric study in the superior colliculus
    Y Sauve
    Neural Transplant Program, Department of Pathology, Institute of Ophthalmology, UCL, 11 43 Bath Street, London EC1V 9EL, UK
    Neuroscience 103:51-63. 2001
  5. ncbi request reprint Extrusion transplantation of Schwann cells into the adult rat thalamus induces directional host axon growth
    G A Brook
    Norman and Sadie Lee Research Centre, National Institute for Medical Research, Mill Hill, London, United Kingdom
    Exp Neurol 126:31-43. 1994
  6. ncbi request reprint Evolving neurovascular relationships in the RCS rat with age
    S Wang
    Institute of Ophthalmology, University College London, London, UK
    Curr Eye Res 27:183-96. 2003
  7. ncbi request reprint Current prospects for adult stem cell-based therapies in ocular repair and regeneration
    G A Limb
    Ocular Repair and Regeneration Biology Unit, Departments of Cell Biology and Pathology, Institute of Ophthalmology, UCL and Moorfields Eye Hospital, 11 Bath Street, London, UK
    Curr Eye Res 31:381-90. 2006
  8. ncbi request reprint Transplantation of syngeneic Schwann cells to the retina of the rhodopsin knockout (rho(-/-)) mouse
    David J Keegan
    Department of Pathology, Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 44:3526-32. 2003
  9. ncbi request reprint MIO-M1 cells and similar muller glial cell lines derived from adult human retina exhibit neural stem cell characteristics
    Jean M Lawrence
    Ocular Repair and Regeneration Biology Unit, Department of Cell Biology, Institute of Ophthalmology, London, UK
    Stem Cells 25:2033-43. 2007
  10. doi request reprint Chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted Müller stem cells into degenerating retina
    Shweta Singhal
    Institute of Ophthalmology and Moorfields Eye Hospital, London, United Kingdom
    Stem Cells 26:1074-82. 2008

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Schwann cell grafting into the retina of the dystrophic RCS rat limits functional deterioration. Royal College of Surgeons
    J M Lawrence
    Institute of Ophthalmology, University College London, UK
    Invest Ophthalmol Vis Sci 41:518-28. 2000
    ..To examine whether congenic Schwann cells grafted into the subretinal space of dystrophic Royal College of Surgeons (RCS) rats can prevent photoreceptor loss and maintain visual function...
  2. ncbi request reprint Transplantation of Schwann cell line clones secreting GDNF or BDNF into the retinas of dystrophic Royal College of Surgeons rats
    Jean M Lawrence
    Department of Pathology, Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 45:267-74. 2004
    ....
  3. ncbi request reprint Cell transplantation as a treatment for retinal disease
    R D Lund
    Institute of Ophthalmology, Bath Street, EC1V 9EL, London, UK
    Prog Retin Eye Res 20:415-49. 2001
    ..Here we describe and review recent developments that highlight the necessary steps that should be taken prior to embarking on clinical trials in humans...
  4. ncbi request reprint Progressive visual sensitivity loss in the Royal College of Surgeons rat: perimetric study in the superior colliculus
    Y Sauve
    Neural Transplant Program, Department of Pathology, Institute of Ophthalmology, UCL, 11 43 Bath Street, London EC1V 9EL, UK
    Neuroscience 103:51-63. 2001
    ..This experimental approach provides the background for answering questions arising during the development of potential experimental therapies for retinal degeneration using animal models like the Royal College of Surgeons rat...
  5. ncbi request reprint Extrusion transplantation of Schwann cells into the adult rat thalamus induces directional host axon growth
    G A Brook
    Norman and Sadie Lee Research Centre, National Institute for Medical Research, Mill Hill, London, United Kingdom
    Exp Neurol 126:31-43. 1994
    ..Thus, Schwann cells, transplanted in the form of elongated tracks, can establish bridges across boundary membranes in the brain and carry substantial numbers of nerve fibers from one area to another...
  6. ncbi request reprint Evolving neurovascular relationships in the RCS rat with age
    S Wang
    Institute of Ophthalmology, University College London, London, UK
    Curr Eye Res 27:183-96. 2003
    ..To examine the course of development of vascular disorders in the Royal College of Surgeons (RCS) rat and how these may lead to retinal ganglion cell loss...
  7. ncbi request reprint Current prospects for adult stem cell-based therapies in ocular repair and regeneration
    G A Limb
    Ocular Repair and Regeneration Biology Unit, Departments of Cell Biology and Pathology, Institute of Ophthalmology, UCL and Moorfields Eye Hospital, 11 Bath Street, London, UK
    Curr Eye Res 31:381-90. 2006
    ..Here we discuss the current prospects for the application of various adult ocular stem cells to human therapies for restoration of vision...
  8. ncbi request reprint Transplantation of syngeneic Schwann cells to the retina of the rhodopsin knockout (rho(-/-)) mouse
    David J Keegan
    Department of Pathology, Institute of Ophthalmology, London, United Kingdom
    Invest Ophthalmol Vis Sci 44:3526-32. 2003
    ..To determine whether subretinal Schwann cell transplantation can prolong the survival of photoreceptors in the rhodopsin knockout (rho(-/-)) mouse...
  9. ncbi request reprint MIO-M1 cells and similar muller glial cell lines derived from adult human retina exhibit neural stem cell characteristics
    Jean M Lawrence
    Ocular Repair and Regeneration Biology Unit, Department of Cell Biology, Institute of Ophthalmology, London, UK
    Stem Cells 25:2033-43. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  10. doi request reprint Chondroitin sulfate proteoglycans and microglia prevent migration and integration of grafted Müller stem cells into degenerating retina
    Shweta Singhal
    Institute of Ophthalmology and Moorfields Eye Hospital, London, United Kingdom
    Stem Cells 26:1074-82. 2008
    ....