Debbie Anne Lawlor

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. doi Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN Bristol, UK
    Eur Heart J 34:2519-28. 2013
  2. pmc Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol
    Philip A I Guthrie
    Bristol Genetic Epidemiology Laboratory BGEL, MRC Centre for Causal Analyses in Translational Epidemiology MRC CAiTE, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Clifton BS8 2BN, UK
    Gene 499:8-13. 2012
  3. pmc Associations of mortality with own height using son's height as an instrumental variable
    David Carslake
    MRC Centre for Causal Analyses in Translational Epidemiology CAiTE, School of Social and Community Medicine, University of Bristol, United Kingdom
    Econ Hum Biol 11:351-9. 2013
  4. pmc Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMC Med Genet 13:90. 2012
  5. doi Maternal adiposity--a determinant of perinatal and offspring outcomes?
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Nat Rev Endocrinol 8:679-88. 2012
  6. pmc Association of maternal vitamin D status during pregnancy with bone-mineral content in offspring: a prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol UK
    Lancet 381:2176-83. 2013
  7. doi The Society for Social Medicine John Pemberton Lecture 2011. Developmental overnutrition--an old hypothesis with new importance?
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Int J Epidemiol 42:7-29. 2013
  8. doi Risk factors for variation in 25-hydroxyvitamin D₃ and D₂ concentrations and vitamin D deficiency in children
    Anna Maija Tolppanen
    Medical Research Council, Centre for Causal Analysis in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, 15 23 Oakfield Grove, Clifton, Bristol BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:1202-10. 2012
  9. pmc The Active for Life Year 5 (AFLY5) school based cluster randomised controlled trial: study protocol for a randomized controlled trial
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Trials 12:181. 2011
  10. pmc Physical activity as a treatment for depression: the TREAD randomised trial protocol
    Helen Baxter
    School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Trials 11:105. 2010

Collaborators

Detail Information

Publications112 found, 100 shown here

  1. doi Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN Bristol, UK
    Eur Heart J 34:2519-28. 2013
    ..To explore the causal effect of long-term alcohol consumption on coronary heart disease risk factors...
  2. pmc Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol
    Philip A I Guthrie
    Bristol Genetic Epidemiology Laboratory BGEL, MRC Centre for Causal Analyses in Translational Epidemiology MRC CAiTE, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Clifton BS8 2BN, UK
    Gene 499:8-13. 2012
    ....
  3. pmc Associations of mortality with own height using son's height as an instrumental variable
    David Carslake
    MRC Centre for Causal Analyses in Translational Epidemiology CAiTE, School of Social and Community Medicine, University of Bristol, United Kingdom
    Econ Hum Biol 11:351-9. 2013
    ....
  4. pmc Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMC Med Genet 13:90. 2012
    ..These associations could be explained by confounding...
  5. doi Maternal adiposity--a determinant of perinatal and offspring outcomes?
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Nat Rev Endocrinol 8:679-88. 2012
    ..To date, little high-quality human evidence exists that any of these effects are mediated by epigenetic mechanisms, but approaches to appropriately test this possibility are being developed...
  6. pmc Association of maternal vitamin D status during pregnancy with bone-mineral content in offspring: a prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol UK
    Lancet 381:2176-83. 2013
    ..Maternal vitamin D status in pregnancy is a suggested determinant of bone-mineral content (BMC) in offspring, but has been assessed in small studies. We investigated this association in a large prospective study...
  7. doi The Society for Social Medicine John Pemberton Lecture 2011. Developmental overnutrition--an old hypothesis with new importance?
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Int J Epidemiol 42:7-29. 2013
    ..I conclude with a discussion about the future research and policy implications of evidence to date in this field...
  8. doi Risk factors for variation in 25-hydroxyvitamin D₃ and D₂ concentrations and vitamin D deficiency in children
    Anna Maija Tolppanen
    Medical Research Council, Centre for Causal Analysis in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, 15 23 Oakfield Grove, Clifton, Bristol BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:1202-10. 2012
    ..Suboptimal vitamin D status is common and associated with adverse health outcomes...
  9. pmc The Active for Life Year 5 (AFLY5) school based cluster randomised controlled trial: study protocol for a randomized controlled trial
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Trials 12:181. 2011
    ....
  10. pmc Physical activity as a treatment for depression: the TREAD randomised trial protocol
    Helen Baxter
    School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Trials 11:105. 2010
    ..The aim of this paper is to describe the protocol for a randomised, controlled trial (RCT) designed to evaluate an intervention developed to increase physical activity as a treatment for depression within primary care...
  11. pmc Geographical variation in cardiovascular incidence: results from the British Women's Heart and Health Study
    Lois G Kim
    Department of Medical Statistics Unit, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    BMC Public Health 10:696. 2010
    ..Prevalence of cardiovascular disease (CVD) in women shows regional variations not explained by common risk factors. Analysis of CVD incidence will provide insight into whether there is further divergence between regions with increasing age...
  12. pmc Overweight and obesity knowledge prior to pregnancy: a survey study
    Marloes Dekker Nitert
    School of Medicine, Royal Brisbane Clinical School, The University of Queensland, Brisbane, Australia
    BMC Pregnancy Childbirth 11:96. 2011
    ..Knowledge about increased risks in overweight and obese women could contribute to successful prevention strategies and the aim of this study is to assess current levels of knowledge in a pregnant population...
  13. pmc Associations of maternal pre-pregnancy obesity and excess pregnancy weight gains with adverse pregnancy outcomes and length of hospital stay
    Abdullah A Mamun
    School of Population Health, The University of Queensland, Brisbane, Australia
    BMC Pregnancy Childbirth 11:62. 2011
    ....
  14. pmc Reasons for and consequences of missed appointments in general practice in the UK: questionnaire survey and prospective review of medical records
    Richard D Neal
    North Wales Clinical School, Department of General Practice, University of Cardiff, Wrexham Technology Park, Wrexham LL13 7YP, UK
    BMC Fam Pract 6:47. 2005
    ..Secondary aims are to compare psychological morbidity, and the previous appointments with GPs between subjects and a comparison group...
  15. pmc Childhood socioeconomic position, educational attainment, and adult cardiovascular risk factors: the Aberdeen children of the 1950s cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS7 8QA, United Kingdom
    Am J Public Health 95:1245-51. 2005
    ....
  16. ncbi Season of birth and childhood intelligence: findings from the Aberdeen Children of the 1950s cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Br J Educ Psychol 76:481-99. 2006
    ....
  17. pmc Family socioeconomic position at birth and future cardiovascular disease risk: findings from the Aberdeen Children of the 1950s cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Am J Public Health 96:1271-7. 2006
    ..We assessed the association of father's social class, recorded at the time of birth, with coronary heart disease and stroke in a British cohort of 11106 individuals born in the 1950s...
  18. ncbi Intrauterine growth and intelligence within sibling pairs: findings from the Aberdeen children of the 1950s cohort
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Pediatrics 117:e894-902. 2006
    ..The objective of this study was to examine whether the established positive association between birth weight and childhood psychometric intelligence is seen within singleton sibling pairs from the same family as well as between nonsiblings...
  19. ncbi Association of body mass index measured in childhood, adolescence, and young adulthood with risk of ischemic heart disease and stroke: findings from 3 historical cohort studies
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
    Am J Clin Nutr 83:767-73. 2006
    ..It is unclear whether early life body mass index (BMI; in kg/m(2)) is associated with adult cardiovascular disease...
  20. ncbi The association of oestrogen receptor alpha-haplotypes with cardiovascular risk factors in the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
    Eur Heart J 27:1597-604. 2006
    ..We aimed to replicate these findings in a general population sample...
  21. ncbi Early life predictors of childhood intelligence: findings from the Mater-University study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 20:148-62. 2006
    ....
  22. ncbi Does the new International Diabetes Federation definition of the metabolic syndrome predict CHD any more strongly than older definitions? Findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabetologia 49:41-8. 2006
    ..Our aim was to determine whether the magnitudes of the associations for any of the syndrome definitions are greater than for the individual components...
  23. ncbi Socioeconomic position, cognitive function, and clustering of cardiovascular risk factors in adolescence: findings from the Mater University Study of Pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Psychosom Med 67:862-8. 2005
    ....
  24. ncbi Childhood intelligence, educational attainment and adult body mass index: findings from a prospective cohort and within sibling-pairs analysis
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Int J Obes (Lond) 30:1758-65. 2006
    ..The mechanisms underlying the observed association of childhood intelligence with body mass index (BMI) are unclear and few studies of this association have been prospective in design...
  25. ncbi Early life predictors of adolescent smoking: findings from the Mater-University study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Paediatr Perinat Epidemiol 19:377-87. 2005
    ..There was no association of family income with smoking at age 14 once other explanatory variables were taken into account...
  26. ncbi The association of birthweight and contemporary size with insulin resistance among children from Estonia and Denmark: findings from the European Youth Heart Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Diabet Med 22:921-30. 2005
    ..To assess the associations of birthweight, contemporary body mass index and height with insulin resistance in children...
  27. pmc Adverse socioeconomic position across the lifecourse increases coronary heart disease risk cumulatively: findings from the British women's heart and health study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 59:785-93. 2005
    ..To examine the associations of childhood and adult measurements of socioeconomic position with coronary heart disease (CHD) risk...
  28. pmc Association of socioeconomic position with insulin resistance among children from Denmark, Estonia, and Portugal: cross sectional study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 331:183. 2005
    ....
  29. ncbi The associations of birthweight, gestational age and childhood BMI with type 2 diabetes: findings from the Aberdeen Children of the 1950s cohort
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Diabetologia 49:2614-7. 2006
    ..The aim of this study was to examine the associations of birthweight, gestational age and childhood BMI (assessed at a mean age of 5 years) with a self-report of a doctor diagnosis of diabetes in middle age...
  30. ncbi Cardiovascular risk and hormone replacement therapy
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Curr Opin Obstet Gynecol 18:658-65. 2006
    ..The purpose of this review is to summarize the studies in humans of the relationship between hormone replacement therapy and coronary heart disease and stroke...
  31. ncbi Epidemiologic evidence for the fetal overnutrition hypothesis: findings from the mater-university study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Am J Epidemiol 165:418-24. 2007
    ..0001). In sensitivity analyses taking account of different plausible levels of nonpaternity (up to 15%), the greater maternal effect remained. These findings provide some support for the fetal overnutrition hypothesis...
  32. pmc Maternal and offspring adiposity-related genetic variants and gestational weight gain
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 94:149-55. 2011
    ..Gestational weight gain (GWG) is associated with a range of health outcomes, but little is known about the factors that influence it...
  33. pmc Does maternal weight gain in pregnancy have long-term effects on offspring adiposity? A sibling study in a prospective cohort of 146,894 men from 136,050 families
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 94:142-8. 2011
    ....
  34. ncbi Hyperinsulinaemia and increased risk of breast cancer: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Cancer Causes Control 15:267-75. 2004
    ..To assess the association between fasting insulin levels and breast cancer...
  35. doi Association of existing diabetes, gestational diabetes and glycosuria in pregnancy with macrosomia and offspring body mass index, waist and fat mass in later childhood: findings from a prospective pregnancy cohort
    D A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Diabetologia 53:89-97. 2010
    ....
  36. doi Association of childhood intelligence with risk of coronary heart disease and stroke: findings from the Aberdeen Children of the 1950s cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Eur J Epidemiol 23:695-706. 2008
    ....
  37. ncbi Is Mendelian randomization 'lost in translation?': comments on 'Mendelian randomization equals instrumental variable analysis with genetic instruments' by Wehby et al
    Debbie A Lawlor
    MRC Centre for Causal Analysis in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    Stat Med 27:2750-5. 2008
  38. doi Associations of birth size and duration of breast feeding with cardiorespiratory fitness in childhood: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
    Eur J Epidemiol 23:411-22. 2008
    ..To explore the developmental origins of cardiorespiratory fitness...
  39. doi The association of insulin-like-growth factor 1 (IGF-1) with incident coronary heart disease in women: findings from the prospective British Women's Heart and Health Study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, ul, UK
    Atherosclerosis 201:198-204. 2008
    ..To examine the association of insulin-like-growth factor 1 (IGF-1) with coronary heart disease (CHD) in women...
  40. ncbi Mendelian randomization: using genes as instruments for making causal inferences in epidemiology
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, U K
    Stat Med 27:1133-63. 2008
    ..This paper outlines Mendelian randomization, draws parallels with IV methods, provides examples of implementation of the approach and discusses limitations of the approach and some methods for dealing with these...
  41. ncbi The association of life course socio-economic position with diagnosis, treatment, control and survival of women with diabetes: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabet Med 24:892-900. 2007
    ..To examine the association of socio-economic position (SEP) with the diagnosis, treatment and control of diabetes, and with survival in women with and without Type 2 diabetes...
  42. ncbi Body mass index in middle life and future risk of hospital admission for psychoses or depression: findings from the Renfrew/Paisley study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Psychol Med 37:1151-61. 2007
    ..There is evidence that greater body mass index (BMI) protects against depression, schizophrenia and suicide. However, there is a need for prospective studies...
  43. pmc Associations between childhood intelligence and hospital admissions for unintentional injuries in adulthood: the Aberdeen Children of the 1950s cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, England
    Am J Public Health 97:291-7. 2007
    ..We examined associations between childhood intelligence and hospital admissions for injuries in adulthood...
  44. ncbi Reverse causality and confounding and the associations of overweight and obesity with mortality
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Obesity (Silver Spring) 14:2294-304. 2006
    ..To examine the effect of reverse causality and confounding on the association of BMI with all-cause and cause-specific mortality...
  45. pmc The association of the paraoxonase (PON1) Q192R polymorphism with depression in older women: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, UK
    J Epidemiol Community Health 61:85-7. 2007
    ..In the absence of such studies in non-occupational populations, these conclusions may not be valid...
  46. doi Mechanisms underlying the associations of maternal age with adverse perinatal outcomes: a sibling study of 264 695 Danish women and their firstborn offspring
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Research, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Int J Epidemiol 40:1205-14. 2011
    ..The mechanisms underlying the association between maternal age (both young and older maternal age) and adverse perinatal outcomes are unclear...
  47. ncbi The challenge of secondary prevention for coronary heart disease in older patients: findings from the British Women's Heart and Health Study and the British Regional Heart Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
    Fam Pract 21:582-6. 2004
    ..Secondary prevention of coronary heart disease (CHD) among older individuals is associated with considerable benefit...
  48. ncbi The metabolic syndrome and coronary heart disease in older women: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabet Med 21:906-13. 2004
    ..To compare two proposed definitions of the metabolic syndrome and to determine the clinical importance of the syndrome with respect to its association with coronary heart disease (CHD)...
  49. pmc Socioeconomic position in childhood and adulthood and insulin resistance: cross sectional survey using data from British women's heart and health study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 325:805. 2002
    ..To assess the associations between childhood and adulthood social class and insulin resistance...
  50. ncbi Is there a sex difference in the association between birth weight and systolic blood pressure in later life? Findings from a meta-regression analysis
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, United Kingdom
    Am J Epidemiol 156:1100-4. 2002
    ..These findings suggest that reports of sex differences in the association between birth weight and blood pressure are chance findings...
  51. pmc The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysis
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    BMC Genet 5:17. 2004
    ..We have examined the association of the PON1 Q192R polymorphism with CHD in a large cohort of British women and combined the results from our cohort study with those from all other published studies...
  52. ncbi Life course influences on insulin resistance: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, U K
    Diabetes Care 26:97-103. 2003
    ..To assess the independent associations of a broad range of early life risk factors and adult obesity with adult insulin resistance...
  53. pmc Associations of components of adult height with coronary heart disease in postmenopausal women: the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Heart 90:745-9. 2004
    ..To assess the associations between components of adult height and coronary heart disease (CHD) in postmenopausal women...
  54. ncbi Commentary: the hormone replacement-coronary heart disease conundrum: is this the death of observational epidemiology?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Int J Epidemiol 33:464-7. 2004
  55. ncbi Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Lancet 363:1724-7. 2004
  56. ncbi Commentary: the art and science of epidemiology: governed by the seasons?
    D A Lawlor
    University of Bristol, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    Int J Epidemiol 33:144-6. 2004
  57. pmc Temperature at birth, coronary heart disease, and insulin resistance: cross sectional analyses of the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Heart 90:381-8. 2004
    ..To assess the association of mean outdoor temperature around the time of birth with insulin resistance and coronary heart disease in later life...
  58. pmc Teenage pregnancy rates: high compared with where and when?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J R Soc Med 97:121-3. 2004
  59. ncbi Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with child-rearing? Findings from the British Women's Heart and Health Study and the British Regional Heart St
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Circulation 107:1260-4. 2003
    ..Parity is associated with coronary heart disease (CHD) risk. In the present study, we assessed the associations between number of children and CHD in both women and men...
  60. ncbi Agreement between measured and self-reported weight in older women. Results from the British Women's Heart and Health Study
    Debbie Anne Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Age Ageing 31:169-74. 2002
    ..The cultural pressures that may cause the tendency among younger women to underestimate their weight, particularly when they are overweight, may operate differently in older women...
  61. ncbi Association between leg length and offspring birthweight: partial explanation for the trans-generational association between birthweight and cardiovascular disease: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 17:148-55. 2003
    ....
  62. pmc Association between offspring birth weight and atherosclerosis in middle aged men and women: British Regional Heart Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 57:462-3. 2003
  63. pmc Association between childhood socioeconomic status and coronary heart disease risk among postmenopausal women: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, England
    Am J Public Health 94:1386-92. 2004
    ..We assessed the association between childhood socioeconomic status (SES) and coronary heart disease among postmenopausal women...
  64. ncbi The association between components of adult height and Type II diabetes and insulin resistance: British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Diabetologia 45:1097-106. 2002
    ..The aim of this study was to investigate the associations between components of adult height (leg length, trunk length, ratio of leg to trunk length) and Type II (non-insulin-dependent) diabetes mellitus and insulin resistance...
  65. pmc Infant feeding and components of the metabolic syndrome: findings from the European Youth Heart Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Arch Dis Child 90:582-8. 2005
    ..To assess the associations of type and duration of infant feeding with components of the metabolic syndrome in children aged 9 and 15...
  66. pmc Do British travel agents provide adequate health advice for travellers?
    D A Lawlor
    Department of Social Medicine, University of Bristol
    Br J Gen Pract 50:567-8. 2000
    ..This study, using covert researchers, suggests this potential is not being fully utilised...
  67. pmc Sex matters: secular and geographical trends in sex differences in coronary heart disease mortality
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 323:541-5. 2001
    ..To examine secular trends and geographical variations in sex differences in mortality from coronary heart disease and investigate how these relate to distributions in risk factors...
  68. ncbi Association of body mass index and obesity measured in early childhood with risk of coronary heart disease and stroke in middle age: findings from the aberdeen children of the 1950s prospective cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, United Kingdom
    Circulation 111:1891-6. 2005
    ..There is concern that the childhood epidemic of obesity will result in increases in the risk of cardiovascular disease in the future; however, there is currently little direct evidence on this issue...
  69. pmc Intrauterine growth and intelligence within sibling pairs: findings from the Mater-University study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 59:279-82. 2005
    ..To examine the association between intrauterine growth and intelligence...
  70. pmc Insulin resistance and depressive symptoms in middle aged men: findings from the Caerphilly prospective cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 330:705-6. 2005
  71. pmc Associations of adult measures of childhood growth with breast cancer: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Br J Cancer 89:81-7. 2003
    ..93, 1.80). These associations were all independent of each other and other potential confounding factors and are likely to reflect different mechanisms by which factors operating prenatally and prepubertally influence breast cancer risk...
  72. pmc Life-course socioeconomic position, area deprivation, and coronary heart disease: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, England
    Am J Public Health 95:91-7. 2005
    ..We sought to determine whether residential area deprivation, over and above the effect of life-course socioeconomic status or position (SEP), is associated with coronary heart disease...
  73. pmc Is housework good for health? Levels of physical activity and factors associated with activity in elderly women. Results from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 56:473-8. 2002
    ..To determine the prevalence of achieving new recommended levels of physical activity, the types of activity involved, and their determinants among elderly British women...
  74. ncbi Associations of parental, birth, and early life characteristics with systolic blood pressure at 5 years of age: findings from the Mater-University study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
    Circulation 110:2417-23. 2004
    ..We examined the associations of a range of parental and early life characteristics with systolic blood pressure at 5 years of age...
  75. pmc Aspirin use for the prevention of cardiovascular disease: the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
    Br J Gen Pract 51:743-5. 2001
    ..Improvements in this area of medical practice are both necessary and feasible...
  76. pmc Association between childhood and adulthood socioeconomic position and pregnancy induced hypertension: results from the Aberdeen children of the 1950s cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 59:49-55. 2005
    ..Childhood socioeconomic adversity is associated with increased cardiovascular disease risk but the association with pregnancy induced hypertension is unknown...
  77. ncbi Adult blood pressure and climate conditions in infancy: a test of the hypothesis that dehydration in infancy is associated with higher adult blood pressure
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Am J Epidemiol 163:608-14. 2006
    ..These findings provide some evidence in favor of the hypothesis that dehydration in infancy is associated with higher adult blood pressure...
  78. doi Randomised controlled trial adapting US school obesity prevention to England
    R R Kipping
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    Arch Dis Child 93:469-73. 2008
    ..To determine whether a school obesity prevention project developed in the United States can be adapted for use in England...
  79. ncbi The effect of physical activity advice given in routine primary care consultations: a systematic review
    D A Lawlor
    Department of Social Medicine, University of Bristol
    J Public Health Med 23:219-26. 2001
    ..Brief advice in primary care to adopt a more active lifestyle may be similarly effective. The aim of this review is to determine the effect of advice given in routine primary care consultations on levels of physical activity...
  80. ncbi Caring for the health of the public: cross sectional study of the activities of UK public health departments
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Public Health 116:102-5. 2002
    ....
  81. pmc The challenges of evaluating environmental interventions to increase population levels of physical activity: the case of the UK National Cycle Network
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 57:96-101. 2003
  82. pmc Performance of the WHO Rose angina questionnaire in post-menopausal women: are all of the questions necessary?
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 57:538-41. 2003
    ..To assess the performance of a shortened version of the Rose angina questionnaire focusing on exertional chest pain...
  83. ncbi Associations of measures of lung function with insulin resistance and Type 2 diabetes: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabetologia 47:195-203. 2004
    ..The aim of this study was to assess the associations of lung function with insulin resistance and Type 2 diabetes...
  84. pmc Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    J Epidemiol Community Health 57:134-40. 2003
    ..To measure the geographical variation in prevalence of cardiovascular disease, risk factors, and their control in a nationally representative sample of older British women...
  85. pmc Association between self-reported childhood socioeconomic position and adult lung function: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Thorax 59:199-203. 2004
    ..A study was undertaken to assess the associations between indicators of early life socioeconomic position and lung function in older adulthood...
  86. pmc Association of birth weight with adult lung function: findings from the British Women's Heart and Health Study and a meta-analysis
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    Thorax 60:851-8. 2005
    ....
  87. ncbi Avoiding milk is associated with a reduced risk of insulin resistance and the metabolic syndrome: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    Diabet Med 22:808-11. 2005
    ..To examine the association of milk consumption with insulin resistance and the metabolic syndrome...
  88. pmc Smoking before the birth of a first child is not associated with increased risk of breast cancer: findings from the British Women's Heart and Health Cohort Study and a meta-analysis
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS7 8QA, UK
    Br J Cancer 91:512-8. 2004
    ..07 (0.94, 1.22). We conclude that smoking prior to the birth of a first child is not associated with increased risk of breast cancer...
  89. pmc Is being overweight associated with behavioural problems in childhood and adolescence? Findings from the Mater-University study of pregnancy and its outcomes
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Arch Dis Child 90:692-7. 2005
    ..To examine the associations between being overweight and behavioural problems at ages 5 and 14...
  90. pmc Birth weight is inversely associated with coronary heart disease in post-menopausal women: findings from the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 58:120-5. 2004
    ....
  91. ncbi Searching multiple databases for systematic reviews: added value or diminishing returns?
    C Stevinson
    Department of Exercise and Health Sciences, Centre for Sport, Exercise and Health, University of Bristol, Tyndall Avenue, Bristol BS8 1TP, UK
    Complement Ther Med 12:228-32. 2004
    ..To explore whether searching specialised bibliographic databases identified additional relevant papers to those located by a Medline search for a systematic review of exercise therapy...
  92. pmc Cardiovascular disease risk assessment in older women: can we improve on Framingham? British Women's Heart and Health prospective cohort study
    M May
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Heart 92:1396-401. 2006
    ..To develop a cardiovascular risk assessment tool that is feasible and easy to use in primary care (general practice (GP) model)...
  93. pmc Parental smoking during pregnancy and offspring bone mass at age 10 years: findings from a prospective birth cohort
    C Macdonald-Wallis
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Osteoporos Int 22:1809-19. 2011
    ..This appears to be due to familial factors related to parental smoking influencing increased offspring adiposity rather than a direct intrauterine effect...
  94. ncbi The detection, treatment and control of high blood pressure in older British adults: cross-sectional findings from the British Women's Heart and Health Study and the British Regional Heart Study
    R Patel
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Hum Hypertens 20:733-41. 2006
    ..We conclude that targets of good control are rarely met in older individuals, who would benefit from the associated reduction in cardiovascular disease risk...
  95. ncbi The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysis
    S J Lewis
    Department of Social Medicine, University of Bristol, Whiteladies Road, Bristol, UK
    Mol Psychiatry 11:352-60. 2006
    ..36 (95% CI: 1.11, 1.67, P=0.003). Since this genotype influences the functioning of the folate metabolic pathway, these findings suggest that folate or its derivatives may be causally related to risk of depression...
  96. doi Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study
    L D Howe
    Department of Social Medicine, University of Bristol, Bristol BS8 2BN, UK
    Int J Obes (Lond) 34:1149-59. 2010
    ....
  97. pmc The effectiveness of exercise as an intervention in the management of depression: systematic review and meta-regression analysis of randomised controlled trials
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    BMJ 322:763-7. 2001
    ..To determine the effectiveness of exercise as an intervention in the management of depression...
  98. doi Physical activity in older women: associations with area deprivation and with socioeconomic position over the life course: observations in the British Women's Heart and Health Study
    M Hillsdon
    Department of Exercise and Health Sciences, University of Bristol, Tyndall Avenue, Bristol BS8 1TP, UK
    J Epidemiol Community Health 62:344-50. 2008
    ..To assess the association between residential area-level deprivation, individual life-course socioeconomic position and adult levels of physical activity in older British women...
  99. ncbi The associations between height components (leg and trunk length) and adult levels of liver enzymes
    A Fraser
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    J Epidemiol Community Health 62:48-53. 2008
    ....
  100. ncbi Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-Analysis
    Abigail Fraser
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS8 2PR, UK
    Arterioscler Thromb Vasc Biol 27:2729-35. 2007
    ..Alanine aminotransferase (ALT) is the enzyme most closely associated with liver fat content...
  101. pmc Do children from an inner city British school meet the recommended levels of physical activity? Results from a cross sectional survey using objective measurements of physical activity
    T Trayers
    Department of Exercise and Health Sciences, University of Bristol, UK
    Arch Dis Child 91:175-6. 2006
    ..However, this finding was dependent on the threshold used to define moderate activity...