Debbie Anne Lawlor

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc Role of endogenous oestrogen in aetiology of coronary heart disease: analysis of age related trends in coronary heart disease and breast cancer in England and Wales and Japan
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 325:311-2. 2002
  2. pmc Smoking before the birth of a first child is not associated with increased risk of breast cancer: findings from the British Women's Heart and Health Cohort Study and a meta-analysis
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS7 8QA, UK
    Br J Cancer 91:512-8. 2004
  3. pmc The challenges of evaluating environmental interventions to increase population levels of physical activity: the case of the UK National Cycle Network
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 57:96-101. 2003
  4. ncbi Leptin and coronary heart disease risk: prospective case control study of British women
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Obesity (Silver Spring) 15:1694-701. 2007
  5. pmc The association of fasting insulin, glucose, and lipids with bone mass in adolescents: findings from a cross-sectional study
    Debbie A Lawlor
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:2068-76. 2012
  6. ncbi (Mis)use of factor analysis in the study of insulin resistance syndrome
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Am J Epidemiol 159:1013-8. 2004
  7. ncbi Avoiding milk is associated with a reduced risk of insulin resistance and the metabolic syndrome: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    Diabet Med 22:808-11. 2005
  8. pmc Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    J Epidemiol Community Health 57:134-40. 2003
  9. ncbi Associations of fibrinogen and C-reactive protein with prevalent and incident coronary heart disease are attenuated by adjustment for confounding factors. British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Thromb Haemost 93:955-63. 2005
  10. ncbi The associations of physical activity and adiposity with alanine aminotransferase and gamma-glutamyltransferase
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol Medical School, Bristol, United Kingdom
    Am J Epidemiol 161:1081-8. 2005

Collaborators

Detail Information

Publications145 found, 100 shown here

  1. pmc Role of endogenous oestrogen in aetiology of coronary heart disease: analysis of age related trends in coronary heart disease and breast cancer in England and Wales and Japan
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 325:311-2. 2002
  2. pmc Smoking before the birth of a first child is not associated with increased risk of breast cancer: findings from the British Women's Heart and Health Cohort Study and a meta-analysis
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS7 8QA, UK
    Br J Cancer 91:512-8. 2004
    ..07 (0.94, 1.22). We conclude that smoking prior to the birth of a first child is not associated with increased risk of breast cancer...
  3. pmc The challenges of evaluating environmental interventions to increase population levels of physical activity: the case of the UK National Cycle Network
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 57:96-101. 2003
  4. ncbi Leptin and coronary heart disease risk: prospective case control study of British women
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Obesity (Silver Spring) 15:1694-701. 2007
    ..Our objective was to examine the association of serum leptin levels with CHD in a prospective study of women...
  5. pmc The association of fasting insulin, glucose, and lipids with bone mass in adolescents: findings from a cross-sectional study
    Debbie A Lawlor
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:2068-76. 2012
    ..It is unclear whether variation in insulin resistance mediates the positive association of fat mass with bone mass in children/adolescents...
  6. ncbi (Mis)use of factor analysis in the study of insulin resistance syndrome
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Am J Epidemiol 159:1013-8. 2004
    ..However, to date none of the studies has adopted this approach, and other statistical approaches and study designs are likely to provide greater understanding of the syndrome...
  7. ncbi Avoiding milk is associated with a reduced risk of insulin resistance and the metabolic syndrome: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
    Diabet Med 22:808-11. 2005
    ..To examine the association of milk consumption with insulin resistance and the metabolic syndrome...
  8. pmc Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    J Epidemiol Community Health 57:134-40. 2003
    ..To measure the geographical variation in prevalence of cardiovascular disease, risk factors, and their control in a nationally representative sample of older British women...
  9. ncbi Associations of fibrinogen and C-reactive protein with prevalent and incident coronary heart disease are attenuated by adjustment for confounding factors. British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Thromb Haemost 93:955-63. 2005
    ..We conclude that fibrinogen and CRP predict CHD but may not be causally related to it...
  10. ncbi The associations of physical activity and adiposity with alanine aminotransferase and gamma-glutamyltransferase
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol Medical School, Bristol, United Kingdom
    Am J Epidemiol 161:1081-8. 2005
    ..These findings provide some support for the suggestion that the relation between obesity and diabetes is, at least in part, mediated by liver pathology...
  11. pmc Birth weight is inversely associated with coronary heart disease in post-menopausal women: findings from the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 58:120-5. 2004
    ....
  12. ncbi Secular trends in mortality by stroke subtype in the 20th century: a retrospective analysis
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Lancet 360:1818-23. 2002
    ....
  13. ncbi Systematic review of the epidemiologic and trial evidence of an association between antidepressant medication and breast cancer
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Clin Epidemiol 56:155-63. 2003
    ..We conclude that epidemiologic evidence does not support an association between antidepressant use and breast cancer...
  14. pmc Association between falls in elderly women and chronic diseases and drug use: cross sectional study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 327:712-7. 2003
    ..To assess the associations between having had a fall and chronic diseases and drug use in elderly women...
  15. ncbi The effect of physical activity advice given in routine primary care consultations: a systematic review
    D A Lawlor
    Department of Social Medicine, University of Bristol
    J Public Health Med 23:219-26. 2001
    ..Brief advice in primary care to adopt a more active lifestyle may be similarly effective. The aim of this review is to determine the effect of advice given in routine primary care consultations on levels of physical activity...
  16. pmc Birth weight of offspring and insulin resistance in late adulthood: cross sectional survey
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 325:359. 2002
    ..To investigate the association between birth weight of offspring and mothers' insulin resistance in late adulthood...
  17. pmc Rurality, deprivation, and excess winter mortality: an ecological study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol UK
    J Epidemiol Community Health 56:373-4. 2002
  18. ncbi The developmental origins of health and disease: where do we go from here?
    Debbie A Lawlor
    MRC Centre of Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    Epidemiology 19:206-8. 2008
    ....
  19. pmc Socioeconomic position and hormone replacement therapy use: explaining the discrepancy in evidence from observational and randomized controlled trials
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS7 8QA, UK
    Am J Public Health 94:2149-54. 2004
    ..We assessed the association between life-course socioeconomic status or position (SEP) and hormone replacement therapy (HRT)...
  20. doi Association of maternal diabetes mellitus in pregnancy with offspring adiposity into early adulthood: sibling study in a prospective cohort of 280,866 men from 248,293 families
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN, UK
    Circulation 123:258-65. 2011
    ..It is unclear whether it is associated with greater adiposity into adulthood, and if so, whether this is via intrauterine mechanisms or shared familial characteristics...
  21. pmc Association between self-reported childhood socioeconomic position and adult lung function: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Thorax 59:199-203. 2004
    ..A study was undertaken to assess the associations between indicators of early life socioeconomic position and lung function in older adulthood...
  22. pmc Is being overweight associated with behavioural problems in childhood and adolescence? Findings from the Mater-University study of pregnancy and its outcomes
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Arch Dis Child 90:692-7. 2005
    ..To examine the associations between being overweight and behavioural problems at ages 5 and 14...
  23. pmc Sex differences in body fat distribution and carotid intima media thickness: cross sectional survey using data from the British regional heart study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    J Epidemiol Community Health 58:700-4. 2004
    ..To determine the role of central adiposity in explaining sex differences in carotid intima media thickness (IMT)...
  24. ncbi Associations of measures of lung function with insulin resistance and Type 2 diabetes: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabetologia 47:195-203. 2004
    ..The aim of this study was to assess the associations of lung function with insulin resistance and Type 2 diabetes...
  25. doi Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    J Intern Med 269:525-37. 2011
    ..We used genetic variants that are robustly associated with adiposity to examine the causal association of adiposity with psychological distress...
  26. pmc Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable
    Debbie A Lawlor
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    PLoS Med 5:e33. 2008
    ..If true, this would result in the obesity epidemic progressing across generations irrespective of environmental or genetic changes. It is therefore important to robustly test this hypothesis...
  27. ncbi Caring for the health of the public: cross sectional study of the activities of UK public health departments
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Public Health 116:102-5. 2002
    ....
  28. ncbi Birth weight is inversely associated with incident coronary heart disease and stroke among individuals born in the 1950s: findings from the Aberdeen Children of the 1950s prospective cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, BS8 2PR, United Kingdom
    Circulation 112:1414-8. 2005
    ....
  29. pmc Independent associations of fasting insulin, glucose, and glycated haemoglobin with stroke and coronary heart disease in older women
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, United Kingdom
    PLoS Med 4:e263. 2007
    ..Our aim was to determine the independent associations of fasting insulin, glucose, and glycated haemoglobin with coronary heart disease and stroke in older women...
  30. ncbi The association of the PON1 Q192R polymorphism with complications and outcomes of pregnancy: findings from the British Women's Heart and Health cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 20:244-50. 2006
    ..02, 1.39]. Our findings provide some further evidence to suggest that PON1 Q192R is associated with preterm birth; they invite further investigation of both maternal and fetal genotype for PON1 Q192R in relation to preterm birth...
  31. ncbi Plasma adiponectin levels are associated with insulin resistance, but do not predict future risk of coronary heart disease in women
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
    J Clin Endocrinol Metab 90:5677-83. 2005
    ..Many observers thus already consider adiponectin to be a major part of the "common soil" underpinning diabetes and vascular disease...
  32. pmc Association of birth weight with adult lung function: findings from the British Women's Heart and Health Study and a meta-analysis
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    Thorax 60:851-8. 2005
    ....
  33. ncbi Sex differences in the association between birth weight and total cholesterol. A meta-analysis
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, United Kingdom
    Ann Epidemiol 16:19-25. 2006
    ..Determine whether a sex difference exists in the association between birth weight and total cholesterol later in life...
  34. pmc Early life predictors of childhood intelligence: evidence from the Aberdeen children of the 1950s study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 59:656-63. 2005
    ..To identify the early life predictors of childhood intelligence...
  35. pmc Smoking and ill health: does lay epidemiology explain the failure of smoking cessation programs among deprived populations?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, England
    Am J Public Health 93:266-70. 2003
    ..Health promotion initiatives designed to reduce smoking among members of these groups may continue to fail unless the general health and life chances of such individuals are first improved...
  36. pmc Association of insulin resistance with depression: cross sectional findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 327:1383-4. 2003
  37. pmc Performance of the WHO Rose angina questionnaire in post-menopausal women: are all of the questions necessary?
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 57:538-41. 2003
    ..To assess the performance of a shortened version of the Rose angina questionnaire focusing on exertional chest pain...
  38. ncbi A comparison of the association between socioeconomic position and cardiovascular disease risk factors in three age cohorts of Australian women: findings from the Australian Longitudinal Study on Women's Health
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, UK
    J Public Health (Oxf) 27:378-87. 2005
    ..To assess the associations between three measurements of socioeconomic position (SEP) -- education, occupation and ability to cope on available income -- and cardiovascular risk factors in three age cohorts of Australian women...
  39. pmc Familial associations of adiposity: findings from a cross-sectional study of 12,181 parental-offspring trios from Belarus
    Rita Patel
    School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 6:e14607. 2011
    ..We aimed to examine these associations in one of the largest studies to date using data from a low-middle income country that has recently undergone a major political and economic transition...
  40. pmc Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adolescence: prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol BS8 2BN, UK
    BMJ 341:c6224. 2010
    ..To examine the prospective associations between body mass index (BMI), waist circumference, and fat mass in childhood and cardiovascular risk factors at age 15-16...
  41. pmc The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    PLoS ONE 3:e3011. 2008
    ..Our objective was to examine the association between CRP genetic variant +1444C>T (rs1130864) and CHD risk in the largest study to date of this association...
  42. pmc Nonalcoholic fatty liver disease, liver fibrosis, and cardiometabolic risk factors in adolescence: a cross-sectional study of 1874 general population adolescents
    Debbie A Lawlor
    Medical Research Council Integrative Epidemiology Unit D A L, C M W, E A, A F, L D H and School of Social and Community Medicine D A L, C M W, E A, A F, L D H, University of Bristol, Bristol BS8 2BN, United Kingdom University Hospitals Bristol National Health Service Foundation Trust M C, Bristol BS1 3NU, United Kingdom Institute of Cellular Medicine C D, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE1 7RU, United Kingdom and Institute of Cardiovascular and Medical Sciences N S, BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow G12 8TA, United Kingdom
    J Clin Endocrinol Metab 99:E410-7. 2014
    ..The impact of adolescent nonalcoholic fatty liver disease (NAFLD) on health, independent of fat mass, is unclear...
  43. pmc Survival with treated and well-controlled blood pressure: findings from a prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 6:e17792. 2011
    ..To compare survival and incident cardiovascular disease between normotensive, untreated hypertensive, treated and poorly-controlled hypertensive and treated and well-controlled hypertensive adults...
  44. pmc Associations of maternal 25-hydroxyvitamin D in pregnancy with offspring cardiovascular risk factors in childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children
    Dylan M Williams
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Heart 99:1849-56. 2013
    ..We examined associations of maternal total 25-hydroxyvitamin D (25(OH)D) in pregnancy with offspring cardiovascular risk factors assessed in childhood and adolescence...
  45. pmc Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
    Abigail Fraser
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Int J Epidemiol 42:97-110. 2013
    ..Details of how to access these data are provided in this cohort profile...
  46. pmc The association of 25-hydroxyvitamin D3 and D2 with behavioural problems in childhood
    Anna Maija Tolppanen
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e40097. 2012
    ..Concentrations of 1,25-dihydroxyvitamin D(3) (the active vitamin D(3) metabolite) have been associated with openness and extrovert behaviour, but 25(OH)D concentrations have not been associated with behavioural problems in humans...
  47. pmc Serum 25-hydroxyvitamin D3 and D2 and non-clinical psychotic experiences in childhood
    Anna Maija Tolppanen
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    PLoS ONE 7:e41575. 2012
    ....
  48. pmc Cardiovascular biomarkers and vascular function during childhood in the offspring of mothers with hypertensive disorders of pregnancy: findings from the Avon Longitudinal Study of Parents and Children
    Debbie Anne Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK
    Eur Heart J 33:335-45. 2012
    ....
  49. pmc Obstetrician-assessed maternal health at pregnancy predicts offspring future health
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, United Kingdom
    PLoS ONE 2:e666. 2007
    ..We aimed to examine the association between obstetrician assessment of maternal physical health at the time of pregnancy and offspring cardiovascular disease risk...
  50. doi Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, BS8 2BN Bristol, UK
    Eur Heart J 34:2519-28. 2013
    ..To explore the causal effect of long-term alcohol consumption on coronary heart disease risk factors...
  51. pmc Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol
    Philip A I Guthrie
    Bristol Genetic Epidemiology Laboratory BGEL, MRC Centre for Causal Analyses in Translational Epidemiology MRC CAiTE, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Clifton BS8 2BN, UK
    Gene 499:8-13. 2012
    ....
  52. pmc Associations of mortality with own height using son's height as an instrumental variable
    David Carslake
    MRC Centre for Causal Analyses in Translational Epidemiology CAiTE, School of Social and Community Medicine, University of Bristol, United Kingdom
    Econ Hum Biol 11:351-9. 2013
    ....
  53. pmc Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children
    Carolina Bonilla
    School of Social and Community Medicine, University of Bristol, Bristol, UK
    BMC Med Genet 13:90. 2012
    ..These associations could be explained by confounding...
  54. doi Maternal adiposity--a determinant of perinatal and offspring outcomes?
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Nat Rev Endocrinol 8:679-88. 2012
    ..To date, little high-quality human evidence exists that any of these effects are mediated by epigenetic mechanisms, but approaches to appropriately test this possibility are being developed...
  55. pmc Association of maternal vitamin D status during pregnancy with bone-mineral content in offspring: a prospective cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol UK
    Lancet 381:2176-83. 2013
    ..Maternal vitamin D status in pregnancy is a suggested determinant of bone-mineral content (BMC) in offspring, but has been assessed in small studies. We investigated this association in a large prospective study...
  56. doi The Society for Social Medicine John Pemberton Lecture 2011. Developmental overnutrition--an old hypothesis with new importance?
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Int J Epidemiol 42:7-29. 2013
    ..I conclude with a discussion about the future research and policy implications of evidence to date in this field...
  57. ncbi Risk factors for variation in 25-hydroxyvitamin D₃ and D₂ concentrations and vitamin D deficiency in children
    Anna Maija Tolppanen
    Medical Research Council, Centre for Causal Analysis in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, 15 23 Oakfield Grove, Clifton, Bristol BS8 2BN, United Kingdom
    J Clin Endocrinol Metab 97:1202-10. 2012
    ..Suboptimal vitamin D status is common and associated with adverse health outcomes...
  58. pmc The Active for Life Year 5 (AFLY5) school based cluster randomised controlled trial: study protocol for a randomized controlled trial
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
    Trials 12:181. 2011
    ....
  59. pmc Physical activity as a treatment for depression: the TREAD randomised trial protocol
    Helen Baxter
    School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Trials 11:105. 2010
    ..The aim of this paper is to describe the protocol for a randomised, controlled trial (RCT) designed to evaluate an intervention developed to increase physical activity as a treatment for depression within primary care...
  60. pmc Geographical variation in cardiovascular incidence: results from the British Women's Heart and Health Study
    Lois G Kim
    Department of Medical Statistics Unit, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
    BMC Public Health 10:696. 2010
    ..Prevalence of cardiovascular disease (CVD) in women shows regional variations not explained by common risk factors. Analysis of CVD incidence will provide insight into whether there is further divergence between regions with increasing age...
  61. pmc Overweight and obesity knowledge prior to pregnancy: a survey study
    Marloes Dekker Nitert
    School of Medicine, Royal Brisbane Clinical School, The University of Queensland, Brisbane, Australia
    BMC Pregnancy Childbirth 11:96. 2011
    ..Knowledge about increased risks in overweight and obese women could contribute to successful prevention strategies and the aim of this study is to assess current levels of knowledge in a pregnant population...
  62. pmc Associations of maternal pre-pregnancy obesity and excess pregnancy weight gains with adverse pregnancy outcomes and length of hospital stay
    Abdullah A Mamun
    School of Population Health, The University of Queensland, Brisbane, Australia
    BMC Pregnancy Childbirth 11:62. 2011
    ....
  63. pmc Reasons for and consequences of missed appointments in general practice in the UK: questionnaire survey and prospective review of medical records
    Richard D Neal
    North Wales Clinical School, Department of General Practice, University of Cardiff, Wrexham Technology Park, Wrexham LL13 7YP, UK
    BMC Fam Pract 6:47. 2005
    ..Secondary aims are to compare psychological morbidity, and the previous appointments with GPs between subjects and a comparison group...
  64. ncbi The association of life course socio-economic position with diagnosis, treatment, control and survival of women with diabetes: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Diabet Med 24:892-900. 2007
    ..To examine the association of socio-economic position (SEP) with the diagnosis, treatment and control of diabetes, and with survival in women with and without Type 2 diabetes...
  65. ncbi The associations of birthweight, gestational age and childhood BMI with type 2 diabetes: findings from the Aberdeen Children of the 1950s cohort
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Diabetologia 49:2614-7. 2006
    ..The aim of this study was to examine the associations of birthweight, gestational age and childhood BMI (assessed at a mean age of 5 years) with a self-report of a doctor diagnosis of diabetes in middle age...
  66. ncbi Body mass index in middle life and future risk of hospital admission for psychoses or depression: findings from the Renfrew/Paisley study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Psychol Med 37:1151-61. 2007
    ..There is evidence that greater body mass index (BMI) protects against depression, schizophrenia and suicide. However, there is a need for prospective studies...
  67. ncbi Cardiovascular risk and hormone replacement therapy
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Curr Opin Obstet Gynecol 18:658-65. 2006
    ..The purpose of this review is to summarize the studies in humans of the relationship between hormone replacement therapy and coronary heart disease and stroke...
  68. ncbi Reverse causality and confounding and the associations of overweight and obesity with mortality
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Obesity (Silver Spring) 14:2294-304. 2006
    ..To examine the effect of reverse causality and confounding on the association of BMI with all-cause and cause-specific mortality...
  69. pmc The association of the paraoxonase (PON1) Q192R polymorphism with depression in older women: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, UK
    J Epidemiol Community Health 61:85-7. 2007
    ..In the absence of such studies in non-occupational populations, these conclusions may not be valid...
  70. ncbi Association of childhood intelligence with risk of coronary heart disease and stroke: findings from the Aberdeen Children of the 1950s cohort study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
    Eur J Epidemiol 23:695-706. 2008
    ....
  71. ncbi Epidemiologic evidence for the fetal overnutrition hypothesis: findings from the mater-university study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Am J Epidemiol 165:418-24. 2007
    ..0001). In sensitivity analyses taking account of different plausible levels of nonpaternity (up to 15%), the greater maternal effect remained. These findings provide some support for the fetal overnutrition hypothesis...
  72. pmc Maternal and offspring adiposity-related genetic variants and gestational weight gain
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 94:149-55. 2011
    ..Gestational weight gain (GWG) is associated with a range of health outcomes, but little is known about the factors that influence it...
  73. doi Mechanisms underlying the associations of maternal age with adverse perinatal outcomes: a sibling study of 264 695 Danish women and their firstborn offspring
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Research, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Int J Epidemiol 40:1205-14. 2011
    ..The mechanisms underlying the association between maternal age (both young and older maternal age) and adverse perinatal outcomes are unclear...
  74. pmc Do British travel agents provide adequate health advice for travellers?
    D A Lawlor
    Department of Social Medicine, University of Bristol
    Br J Gen Pract 50:567-8. 2000
    ..This study, using covert researchers, suggests this potential is not being fully utilised...
  75. ncbi Association of existing diabetes, gestational diabetes and glycosuria in pregnancy with macrosomia and offspring body mass index, waist and fat mass in later childhood: findings from a prospective pregnancy cohort
    D A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
    Diabetologia 53:89-97. 2010
    ....
  76. ncbi Is Mendelian randomization 'lost in translation?': comments on 'Mendelian randomization equals instrumental variable analysis with genetic instruments' by Wehby et al
    Debbie A Lawlor
    MRC Centre for Causal Analysis in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
    Stat Med 27:2750-5. 2008
  77. ncbi Associations of birth size and duration of breast feeding with cardiorespiratory fitness in childhood: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
    Eur J Epidemiol 23:411-22. 2008
    ..To explore the developmental origins of cardiorespiratory fitness...
  78. pmc Does maternal weight gain in pregnancy have long-term effects on offspring adiposity? A sibling study in a prospective cohort of 146,894 men from 136,050 families
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 94:142-8. 2011
    ....
  79. ncbi The association of insulin-like-growth factor 1 (IGF-1) with incident coronary heart disease in women: findings from the prospective British Women's Heart and Health Study
    Debbie A Lawlor
    MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, ul, UK
    Atherosclerosis 201:198-204. 2008
    ..To examine the association of insulin-like-growth factor 1 (IGF-1) with coronary heart disease (CHD) in women...
  80. ncbi Mendelian randomization: using genes as instruments for making causal inferences in epidemiology
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, U K
    Stat Med 27:1133-63. 2008
    ..This paper outlines Mendelian randomization, draws parallels with IV methods, provides examples of implementation of the approach and discusses limitations of the approach and some methods for dealing with these...
  81. ncbi Season of birth and childhood intelligence: findings from the Aberdeen Children of the 1950s cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Br J Educ Psychol 76:481-99. 2006
    ....
  82. pmc Temperature at birth, coronary heart disease, and insulin resistance: cross sectional analyses of the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Heart 90:381-8. 2004
    ..To assess the association of mean outdoor temperature around the time of birth with insulin resistance and coronary heart disease in later life...
  83. pmc Associations of adult measures of childhood growth with breast cancer: findings from the British Women's Heart and Health Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Br J Cancer 89:81-7. 2003
    ..93, 1.80). These associations were all independent of each other and other potential confounding factors and are likely to reflect different mechanisms by which factors operating prenatally and prepubertally influence breast cancer risk...
  84. pmc Insulin resistance and depressive symptoms in middle aged men: findings from the Caerphilly prospective cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol BS8 2PR
    BMJ 330:705-6. 2005
  85. pmc Intrauterine growth and intelligence within sibling pairs: findings from the Mater-University study of pregnancy and its outcomes
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 59:279-82. 2005
    ..To examine the association between intrauterine growth and intelligence...
  86. pmc Association between offspring birth weight and atherosclerosis in middle aged men and women: British Regional Heart Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    J Epidemiol Community Health 57:462-3. 2003
  87. ncbi Association between leg length and offspring birthweight: partial explanation for the trans-generational association between birthweight and cardiovascular disease: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Paediatr Perinat Epidemiol 17:148-55. 2003
    ....
  88. ncbi Association of body mass index and obesity measured in early childhood with risk of coronary heart disease and stroke in middle age: findings from the aberdeen children of the 1950s prospective cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, United Kingdom
    Circulation 111:1891-6. 2005
    ..There is concern that the childhood epidemic of obesity will result in increases in the risk of cardiovascular disease in the future; however, there is currently little direct evidence on this issue...
  89. ncbi Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with child-rearing? Findings from the British Women's Heart and Health Study and the British Regional Heart St
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Circulation 107:1260-4. 2003
    ..Parity is associated with coronary heart disease (CHD) risk. In the present study, we assessed the associations between number of children and CHD in both women and men...
  90. ncbi Life course influences on insulin resistance: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, U K
    Diabetes Care 26:97-103. 2003
    ..To assess the independent associations of a broad range of early life risk factors and adult obesity with adult insulin resistance...
  91. pmc Infant feeding and components of the metabolic syndrome: findings from the European Youth Heart Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Arch Dis Child 90:582-8. 2005
    ..To assess the associations of type and duration of infant feeding with components of the metabolic syndrome in children aged 9 and 15...
  92. ncbi The association of birthweight and contemporary size with insulin resistance among children from Estonia and Denmark: findings from the European Youth Heart Study
    D A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Diabet Med 22:921-30. 2005
    ..To assess the associations of birthweight, contemporary body mass index and height with insulin resistance in children...
  93. pmc Life-course socioeconomic position, area deprivation, and coronary heart disease: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, England
    Am J Public Health 95:91-7. 2005
    ..We sought to determine whether residential area deprivation, over and above the effect of life-course socioeconomic status or position (SEP), is associated with coronary heart disease...
  94. pmc Association between childhood and adulthood socioeconomic position and pregnancy induced hypertension: results from the Aberdeen children of the 1950s cohort study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    J Epidemiol Community Health 59:49-55. 2005
    ..Childhood socioeconomic adversity is associated with increased cardiovascular disease risk but the association with pregnancy induced hypertension is unknown...
  95. ncbi Commentary: the art and science of epidemiology: governed by the seasons?
    D A Lawlor
    University of Bristol, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
    Int J Epidemiol 33:144-6. 2004
  96. ncbi Hyperinsulinaemia and increased risk of breast cancer: findings from the British Women's Heart and Health Study
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Cancer Causes Control 15:267-75. 2004
    ..To assess the association between fasting insulin levels and breast cancer...
  97. ncbi Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Lancet 363:1724-7. 2004
  98. ncbi Commentary: the hormone replacement-coronary heart disease conundrum: is this the death of observational epidemiology?
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, UK
    Int J Epidemiol 33:464-7. 2004
  99. pmc Associations of components of adult height with coronary heart disease in postmenopausal women: the British women's heart and health study
    D A Lawlor
    Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Heart 90:745-9. 2004
    ..To assess the associations between components of adult height and coronary heart disease (CHD) in postmenopausal women...