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Genomes and GenesSpecies | Debbie Anne LawlorSummaryAffiliation: University of Bristol Country: UK Publications
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Publications
The Society for Social Medicine John Pemberton Lecture 2011. Developmental overnutrition--an old hypothesis with new importance?Debbie A Lawlor
MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
Int J Epidemiol 42:7-29. 2013..I conclude with a discussion about the future research and policy implications of evidence to date in this field...
Risk factors for variation in 25-hydroxyvitamin D₃ and D₂ concentrations and vitamin D deficiency in childrenAnna Maija Tolppanen
Medical Research Council, Centre for Causal Analysis in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Oakfield House, 15 23 Oakfield Grove, Clifton, Bristol BS8 2BN, United Kingdom
J Clin Endocrinol Metab 97:1202-10. 2012..Suboptimal vitamin D status is common and associated with adverse health outcomes...
The Active for Life Year 5 (AFLY5) school based cluster randomised controlled trial: study protocol for a randomized controlled trialDebbie A Lawlor
MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, UK
Trials 12:181. 2011....
Physical activity as a treatment for depression: the TREAD randomised trial protocolHelen Baxter
School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
Trials 11:105. 2010..The aim of this paper is to describe the protocol for a randomised, controlled trial (RCT) designed to evaluate an intervention developed to increase physical activity as a treatment for depression within primary care...
Geographical variation in cardiovascular incidence: results from the British Women's Heart and Health StudyLois G Kim
Department of Medical Statistics Unit, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel St, London WC1E 7HT, UK
BMC Public Health 10:696. 2010..Prevalence of cardiovascular disease (CVD) in women shows regional variations not explained by common risk factors. Analysis of CVD incidence will provide insight into whether there is further divergence between regions with increasing age...
Overweight and obesity knowledge prior to pregnancy: a survey studyMarloes Dekker Nitert
School of Medicine, Royal Brisbane Clinical School, The University of Queensland, Brisbane, Australia
BMC Pregnancy Childbirth 11:96. 2011..Knowledge about increased risks in overweight and obese women could contribute to successful prevention strategies and the aim of this study is to assess current levels of knowledge in a pregnant population...
Associations of maternal pre-pregnancy obesity and excess pregnancy weight gains with adverse pregnancy outcomes and length of hospital stayAbdullah A Mamun
School of Population Health, The University of Queensland, Brisbane, Australia
BMC Pregnancy Childbirth 11:62. 2011....
Reasons for and consequences of missed appointments in general practice in the UK: questionnaire survey and prospective review of medical recordsRichard D Neal
North Wales Clinical School, Department of General Practice, University of Cardiff, Wrexham Technology Park, Wrexham LL13 7YP, UK
BMC Fam Pract 6:47. 2005..Secondary aims are to compare psychological morbidity, and the previous appointments with GPs between subjects and a comparison group...
Socioeconomic position, cognitive function, and clustering of cardiovascular risk factors in adolescence: findings from the Mater University Study of Pregnancy and its outcomesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Psychosom Med 67:862-8. 2005....
Does the new International Diabetes Federation definition of the metabolic syndrome predict CHD any more strongly than older definitions? Findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Diabetologia 49:41-8. 2006..Our aim was to determine whether the magnitudes of the associations for any of the syndrome definitions are greater than for the individual components...
Early life predictors of childhood intelligence: findings from the Mater-University study of pregnancy and its outcomesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Paediatr Perinat Epidemiol 20:148-62. 2006....
The association of oestrogen receptor alpha-haplotypes with cardiovascular risk factors in the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
Eur Heart J 27:1597-604. 2006..We aimed to replicate these findings in a general population sample...
Family socioeconomic position at birth and future cardiovascular disease risk: findings from the Aberdeen Children of the 1950s cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, United Kingdom
Am J Public Health 96:1271-7. 2006..We assessed the association of father's social class, recorded at the time of birth, with coronary heart disease and stroke in a British cohort of 11106 individuals born in the 1950s...
Childhood intelligence, educational attainment and adult body mass index: findings from a prospective cohort and within sibling-pairs analysisD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Int J Obes (Lond) 30:1758-65. 2006..The mechanisms underlying the observed association of childhood intelligence with body mass index (BMI) are unclear and few studies of this association have been prospective in design...
Association of body mass index measured in childhood, adolescence, and young adulthood with risk of ischemic heart disease and stroke: findings from 3 historical cohort studiesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, United Kingdom
Am J Clin Nutr 83:767-73. 2006..It is unclear whether early life body mass index (BMI; in kg/m(2)) is associated with adult cardiovascular disease...
Early life predictors of adolescent smoking: findings from the Mater-University study of pregnancy and its outcomesDebbie A Lawlor
Department of Social Medicine, University of Bristol, UK
Paediatr Perinat Epidemiol 19:377-87. 2005..There was no association of family income with smoking at age 14 once other explanatory variables were taken into account...
Adverse socioeconomic position across the lifecourse increases coronary heart disease risk cumulatively: findings from the British women's heart and health studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J Epidemiol Community Health 59:785-93. 2005..To examine the associations of childhood and adult measurements of socioeconomic position with coronary heart disease (CHD) risk...
Association of socioeconomic position with insulin resistance among children from Denmark, Estonia, and Portugal: cross sectional studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 331:183. 2005....
Childhood socioeconomic position, educational attainment, and adult cardiovascular risk factors: the Aberdeen children of the 1950s cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS7 8QA, United Kingdom
Am J Public Health 95:1245-51. 2005....
The association of birthweight and contemporary size with insulin resistance among children from Estonia and Denmark: findings from the European Youth Heart StudyD A Lawlor
Department of Social Medicine, University of Bristol, UK
Diabet Med 22:921-30. 2005..To assess the associations of birthweight, contemporary body mass index and height with insulin resistance in children...
Infant feeding and components of the metabolic syndrome: findings from the European Youth Heart StudyD A Lawlor
Department of Social Medicine, University of Bristol, UK
Arch Dis Child 90:582-8. 2005..To assess the associations of type and duration of infant feeding with components of the metabolic syndrome in children aged 9 and 15...
Association of body mass index and obesity measured in early childhood with risk of coronary heart disease and stroke in middle age: findings from the aberdeen children of the 1950s prospective cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, United Kingdom
Circulation 111:1891-6. 2005..There is concern that the childhood epidemic of obesity will result in increases in the risk of cardiovascular disease in the future; however, there is currently little direct evidence on this issue...
Intrauterine growth and intelligence within sibling pairs: findings from the Mater-University study of pregnancy and its outcomesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J Epidemiol Community Health 59:279-82. 2005..To examine the association between intrauterine growth and intelligence...
Season of birth and childhood intelligence: findings from the Aberdeen Children of the 1950s cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Br J Educ Psychol 76:481-99. 2006....
The associations of birthweight, gestational age and childhood BMI with type 2 diabetes: findings from the Aberdeen Children of the 1950s cohortD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Diabetologia 49:2614-7. 2006..The aim of this study was to examine the associations of birthweight, gestational age and childhood BMI (assessed at a mean age of 5 years) with a self-report of a doctor diagnosis of diabetes in middle age...
Maternal and offspring adiposity-related genetic variants and gestational weight gainDebbie A Lawlor
MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, United Kingdom
Am J Clin Nutr 94:149-55. 2011..Gestational weight gain (GWG) is associated with a range of health outcomes, but little is known about the factors that influence it...
Does maternal weight gain in pregnancy have long-term effects on offspring adiposity? A sibling study in a prospective cohort of 146,894 men from 136,050 familiesDebbie A Lawlor
MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
Am J Clin Nutr 94:142-8. 2011....
Association of existing diabetes, gestational diabetes and glycosuria in pregnancy with macrosomia and offspring body mass index, waist and fat mass in later childhood: findings from a prospective pregnancy cohortD A Lawlor
MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
Diabetologia 53:89-97. 2010....
Mendelian randomization: using genes as instruments for making causal inferences in epidemiologyDebbie A Lawlor
Department of Social Medicine, University of Bristol, U K
Stat Med 27:1133-63. 2008..This paper outlines Mendelian randomization, draws parallels with IV methods, provides examples of implementation of the approach and discusses limitations of the approach and some methods for dealing with these...
Association of childhood intelligence with risk of coronary heart disease and stroke: findings from the Aberdeen Children of the 1950s cohort studyDebbie A Lawlor
MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK
Eur J Epidemiol 23:695-706. 2008....
Is Mendelian randomization 'lost in translation?': comments on 'Mendelian randomization equals instrumental variable analysis with genetic instruments' by Wehby et alDebbie A Lawlor
MRC Centre for Causal Analysis in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
Stat Med 27:2750-5. 2008
Associations of birth size and duration of breast feeding with cardiorespiratory fitness in childhood: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC)Debbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
Eur J Epidemiol 23:411-22. 2008..To explore the developmental origins of cardiorespiratory fitness...
The association of insulin-like-growth factor 1 (IGF-1) with incident coronary heart disease in women: findings from the prospective British Women's Heart and Health StudyDebbie A Lawlor
MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, ul, UK
Atherosclerosis 201:198-204. 2008..To examine the association of insulin-like-growth factor 1 (IGF-1) with coronary heart disease (CHD) in women...
The association of life course socio-economic position with diagnosis, treatment, control and survival of women with diabetes: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Diabet Med 24:892-900. 2007..To examine the association of socio-economic position (SEP) with the diagnosis, treatment and control of diabetes, and with survival in women with and without Type 2 diabetes...
Body mass index in middle life and future risk of hospital admission for psychoses or depression: findings from the Renfrew/Paisley studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, UK
Psychol Med 37:1151-61. 2007..There is evidence that greater body mass index (BMI) protects against depression, schizophrenia and suicide. However, there is a need for prospective studies...
Associations between childhood intelligence and hospital admissions for unintentional injuries in adulthood: the Aberdeen Children of the 1950s cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, England
Am J Public Health 97:291-7. 2007..We examined associations between childhood intelligence and hospital admissions for injuries in adulthood...
Reverse causality and confounding and the associations of overweight and obesity with mortalityDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Obesity (Silver Spring) 14:2294-304. 2006..To examine the effect of reverse causality and confounding on the association of BMI with all-cause and cause-specific mortality...
The association of the paraoxonase (PON1) Q192R polymorphism with depression in older women: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, UK
J Epidemiol Community Health 61:85-7. 2007..In the absence of such studies in non-occupational populations, these conclusions may not be valid...
Epidemiologic evidence for the fetal overnutrition hypothesis: findings from the mater-university study of pregnancy and its outcomesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Am J Epidemiol 165:418-24. 2007..0001). In sensitivity analyses taking account of different plausible levels of nonpaternity (up to 15%), the greater maternal effect remained. These findings provide some support for the fetal overnutrition hypothesis...
Cardiovascular risk and hormone replacement therapyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Curr Opin Obstet Gynecol 18:658-65. 2006..The purpose of this review is to summarize the studies in humans of the relationship between hormone replacement therapy and coronary heart disease and stroke...
Mechanisms underlying the associations of maternal age with adverse perinatal outcomes: a sibling study of 264 695 Danish women and their firstborn offspringDebbie A Lawlor
MRC Centre for Causal Analyses in Translational Research, School of Social and Community Medicine, University of Bristol, Bristol, UK
Int J Epidemiol 40:1205-14. 2011..The mechanisms underlying the association between maternal age (both young and older maternal age) and adverse perinatal outcomes are unclear...
Insulin resistance and depressive symptoms in middle aged men: findings from the Caerphilly prospective cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 330:705-6. 2005
Intrauterine growth and intelligence within sibling pairs: findings from the Aberdeen children of the 1950s cohortDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, United Kingdom
Pediatrics 117:e894-902. 2006..The objective of this study was to examine whether the established positive association between birth weight and childhood psychometric intelligence is seen within singleton sibling pairs from the same family as well as between nonsiblings...
Is there a sex difference in the association between birth weight and systolic blood pressure in later life? Findings from a meta-regression analysisDebbie A Lawlor
Department of Social Medicine, University of Bristol, United Kingdom
Am J Epidemiol 156:1100-4. 2002..These findings suggest that reports of sex differences in the association between birth weight and blood pressure are chance findings...
Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence?Debbie A Lawlor
Department of Social Medicine, University of Bristol, UK
Lancet 363:1724-7. 2004
Agreement between measured and self-reported weight in older women. Results from the British Women's Heart and Health StudyDebbie Anne Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Age Ageing 31:169-74. 2002..The cultural pressures that may cause the tendency among younger women to underestimate their weight, particularly when they are overweight, may operate differently in older women...
Hyperinsulinaemia and increased risk of breast cancer: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Cancer Causes Control 15:267-75. 2004..To assess the association between fasting insulin levels and breast cancer...
Commentary: the art and science of epidemiology: governed by the seasons?D A Lawlor
University of Bristol, Department of Social Medicine, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
Int J Epidemiol 33:144-6. 2004
Life course influences on insulin resistance: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, U K
Diabetes Care 26:97-103. 2003..To assess the independent associations of a broad range of early life risk factors and adult obesity with adult insulin resistance...
Temperature at birth, coronary heart disease, and insulin resistance: cross sectional analyses of the British women's heart and health studyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Heart 90:381-8. 2004..To assess the association of mean outdoor temperature around the time of birth with insulin resistance and coronary heart disease in later life...
Associations of adult measures of childhood growth with breast cancer: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Br J Cancer 89:81-7. 2003..93, 1.80). These associations were all independent of each other and other potential confounding factors and are likely to reflect different mechanisms by which factors operating prenatally and prepubertally influence breast cancer risk...
Teenage pregnancy rates: high compared with where and when?Debbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J R Soc Med 97:121-3. 2004
Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with child-rearing? Findings from the British Women's Heart and Health Study and the British Regional Heart StDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Circulation 107:1260-4. 2003..Parity is associated with coronary heart disease (CHD) risk. In the present study, we assessed the associations between number of children and CHD in both women and men...
Association between leg length and offspring birthweight: partial explanation for the trans-generational association between birthweight and cardiovascular disease: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Paediatr Perinat Epidemiol 17:148-55. 2003....
Association between offspring birth weight and atherosclerosis in middle aged men and women: British Regional Heart StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
J Epidemiol Community Health 57:462-3. 2003
Socioeconomic position in childhood and adulthood and insulin resistance: cross sectional survey using data from British women's heart and health studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 325:805. 2002..To assess the associations between childhood and adulthood social class and insulin resistance...
Commentary: the hormone replacement-coronary heart disease conundrum: is this the death of observational epidemiology?Debbie A Lawlor
Department of Social Medicine, University of Bristol, UK
Int J Epidemiol 33:464-7. 2004
Associations of components of adult height with coronary heart disease in postmenopausal women: the British women's heart and health studyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Heart 90:745-9. 2004..To assess the associations between components of adult height and coronary heart disease (CHD) in postmenopausal women...
Life-course socioeconomic position, area deprivation, and coronary heart disease: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, England
Am J Public Health 95:91-7. 2005..We sought to determine whether residential area deprivation, over and above the effect of life-course socioeconomic status or position (SEP), is associated with coronary heart disease...
Do British travel agents provide adequate health advice for travellers?D A Lawlor
Department of Social Medicine, University of Bristol
Br J Gen Pract 50:567-8. 2000..This study, using covert researchers, suggests this potential is not being fully utilised...
Association between childhood and adulthood socioeconomic position and pregnancy induced hypertension: results from the Aberdeen children of the 1950s cohort studyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J Epidemiol Community Health 59:49-55. 2005..Childhood socioeconomic adversity is associated with increased cardiovascular disease risk but the association with pregnancy induced hypertension is unknown...
Sex matters: secular and geographical trends in sex differences in coronary heart disease mortalityD A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR
BMJ 323:541-5. 2001..To examine secular trends and geographical variations in sex differences in mortality from coronary heart disease and investigate how these relate to distributions in risk factors...
Associations of parental, birth, and early life characteristics with systolic blood pressure at 5 years of age: findings from the Mater-University study of pregnancy and its outcomesDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, BS8 2PR, UK
Circulation 110:2417-23. 2004..We examined the associations of a range of parental and early life characteristics with systolic blood pressure at 5 years of age...
The challenge of secondary prevention for coronary heart disease in older patients: findings from the British Women's Heart and Health Study and the British Regional Heart StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
Fam Pract 21:582-6. 2004..Secondary prevention of coronary heart disease (CHD) among older individuals is associated with considerable benefit...
Aspirin use for the prevention of cardiovascular disease: the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR
Br J Gen Pract 51:743-5. 2001..Improvements in this area of medical practice are both necessary and feasible...
Association between childhood socioeconomic status and coronary heart disease risk among postmenopausal women: findings from the British Women's Heart and Health StudyDebbie A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol, England
Am J Public Health 94:1386-92. 2004..We assessed the association between childhood socioeconomic status (SES) and coronary heart disease among postmenopausal women...
Is housework good for health? Levels of physical activity and factors associated with activity in elderly women. Results from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J Epidemiol Community Health 56:473-8. 2002..To determine the prevalence of achieving new recommended levels of physical activity, the types of activity involved, and their determinants among elderly British women...
The metabolic syndrome and coronary heart disease in older women: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Diabet Med 21:906-13. 2004..To compare two proposed definitions of the metabolic syndrome and to determine the clinical importance of the syndrome with respect to its association with coronary heart disease (CHD)...
The association between components of adult height and Type II diabetes and insulin resistance: British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, UK
Diabetologia 45:1097-106. 2002..The aim of this study was to investigate the associations between components of adult height (leg length, trunk length, ratio of leg to trunk length) and Type II (non-insulin-dependent) diabetes mellitus and insulin resistance...
The association of the PON1 Q192R polymorphism with coronary heart disease: findings from the British Women's Heart and Health cohort study and a meta-analysisDebbie A Lawlor
Department of Social Medicine, University of Bristol, UK
BMC Genet 5:17. 2004..We have examined the association of the PON1 Q192R polymorphism with CHD in a large cohort of British women and combined the results from our cohort study with those from all other published studies...
Adult blood pressure and climate conditions in infancy: a test of the hypothesis that dehydration in infancy is associated with higher adult blood pressureDebbie A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Am J Epidemiol 163:608-14. 2006..These findings provide some evidence in favor of the hypothesis that dehydration in infancy is associated with higher adult blood pressure...
Randomised controlled trial adapting US school obesity prevention to EnglandR R Kipping
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
Arch Dis Child 93:469-73. 2008..To determine whether a school obesity prevention project developed in the United States can be adapted for use in England...
Caring for the health of the public: cross sectional study of the activities of UK public health departmentsD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Public Health 116:102-5. 2002....
Association of birth weight with adult lung function: findings from the British Women's Heart and Health Study and a meta-analysisD A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
Thorax 60:851-8. 2005....
Smoking before the birth of a first child is not associated with increased risk of breast cancer: findings from the British Women's Heart and Health Cohort Study and a meta-analysisD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS7 8QA, UK
Br J Cancer 91:512-8. 2004..07 (0.94, 1.22). We conclude that smoking prior to the birth of a first child is not associated with increased risk of breast cancer...
The effect of physical activity advice given in routine primary care consultations: a systematic reviewD A Lawlor
Department of Social Medicine, University of Bristol
J Public Health Med 23:219-26. 2001..Brief advice in primary care to adopt a more active lifestyle may be similarly effective. The aim of this review is to determine the effect of advice given in routine primary care consultations on levels of physical activity...
Avoiding milk is associated with a reduced risk of insulin resistance and the metabolic syndrome: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
Diabet Med 22:808-11. 2005..To examine the association of milk consumption with insulin resistance and the metabolic syndrome...
The challenges of evaluating environmental interventions to increase population levels of physical activity: the case of the UK National Cycle NetworkD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
J Epidemiol Community Health 57:96-101. 2003
Association between self-reported childhood socioeconomic position and adult lung function: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Thorax 59:199-203. 2004..A study was undertaken to assess the associations between indicators of early life socioeconomic position and lung function in older adulthood...
Birth weight is inversely associated with coronary heart disease in post-menopausal women: findings from the British women's heart and health studyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
J Epidemiol Community Health 58:120-5. 2004....
Performance of the WHO Rose angina questionnaire in post-menopausal women: are all of the questions necessary?D A Lawlor
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
J Epidemiol Community Health 57:538-41. 2003..To assess the performance of a shortened version of the Rose angina questionnaire focusing on exertional chest pain...
Associations of measures of lung function with insulin resistance and Type 2 diabetes: findings from the British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol, UK
Diabetologia 47:195-203. 2004..The aim of this study was to assess the associations of lung function with insulin resistance and Type 2 diabetes...
Is being overweight associated with behavioural problems in childhood and adolescence? Findings from the Mater-University study of pregnancy and its outcomesD A Lawlor
Department of Social Medicine, University of Bristol, UK
Arch Dis Child 90:692-7. 2005..To examine the associations between being overweight and behavioural problems at ages 5 and 14...
Geographical variation in cardiovascular disease, risk factors, and their control in older women: British Women's Heart and Health StudyD A Lawlor
Department of Social Medicine, University of Bristol, UK
J Epidemiol Community Health 57:134-40. 2003..To measure the geographical variation in prevalence of cardiovascular disease, risk factors, and their control in a nationally representative sample of older British women...
Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort studyL D Howe
Department of Social Medicine, University of Bristol, Bristol BS8 2BN, UK
Int J Obes (Lond) 34:1149-59. 2010....
Parental smoking during pregnancy and offspring bone mass at age 10 years: findings from a prospective birth cohortC Macdonald-Wallis
MRC Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK
Osteoporos Int 22:1809-19. 2011..This appears to be due to familial factors related to parental smoking influencing increased offspring adiposity rather than a direct intrauterine effect...
A modified Mediterranean diet is associated with the greatest reduction in alanine aminotransferase levels in obese type 2 diabetes patients: results of a quasi-randomised controlled trialA Fraser
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol, BS8 2PR, UK
Diabetologia 51:1616-22. 2008..The aim of the study was to compare the effect of different dietary interventions on alanine aminotransferase (ALT) in obese patients with diabetes...
Accuracy of height and weight data from child health recordsL D Howe
Department of Social Medicine, University of Bristol, Bristol, UK
Arch Dis Child 94:950-4. 2009..We assess the accuracy of such measurements, using research measurements as the gold standard...
The effectiveness of exercise as an intervention in the management of depression: systematic review and meta-regression analysis of randomised controlled trialsD A Lawlor
Department of Social Medicine, University of Bristol, Bristol BS8 2PR, UK
BMJ 322:763-7. 2001..To determine the effectiveness of exercise as an intervention in the management of depression...
The thermolabile variant of MTHFR is associated with depression in the British Women's Heart and Health Study and a meta-analysisS J Lewis
Department of Social Medicine, University of Bristol, Whiteladies Road, Bristol, UK
Mol Psychiatry 11:352-60. 2006..36 (95% CI: 1.11, 1.67, P=0.003). Since this genotype influences the functioning of the folate metabolic pathway, these findings suggest that folate or its derivatives may be causally related to risk of depression...
Do children from an inner city British school meet the recommended levels of physical activity? Results from a cross sectional survey using objective measurements of physical activityT Trayers
Department of Exercise and Health Sciences, University of Bristol, UK
Arch Dis Child 91:175-6. 2006..However, this finding was dependent on the threshold used to define moderate activity...
Cardiovascular disease risk assessment in older women: can we improve on Framingham? British Women's Heart and Health prospective cohort studyM May
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, UK
Heart 92:1396-401. 2006..To develop a cardiovascular risk assessment tool that is feasible and easy to use in primary care (general practice (GP) model)...
Physical activity in older women: associations with area deprivation and with socioeconomic position over the life course: observations in the British Women's Heart and Health StudyM Hillsdon
Department of Exercise and Health Sciences, University of Bristol, Tyndall Avenue, Bristol BS8 1TP, UK
J Epidemiol Community Health 62:344-50. 2008..To assess the association between residential area-level deprivation, individual life-course socioeconomic position and adult levels of physical activity in older British women...
Sodium intake in infancy and blood pressure at 7 years: findings from the Avon Longitudinal Study of Parents and ChildrenM J Brion
Department of Social Medicine, University of Bristol, Whiteladies Road, Bristol, Avon, UK
Eur J Clin Nutr 62:1162-9. 2008..Infancy may be a sensitive period regarding effects of sodium intake on future blood pressure (BP). This has only been demonstrated in one randomized trial of low sodium formulae with follow-up in adolescence in one-third of participants...
The detection, treatment and control of high blood pressure in older British adults: cross-sectional findings from the British Women's Heart and Health Study and the British Regional Heart StudyR Patel
Department of Social Medicine, University of Bristol, Bristol, UK
J Hum Hypertens 20:733-41. 2006..We conclude that targets of good control are rarely met in older individuals, who would benefit from the associated reduction in cardiovascular disease risk...
Searching multiple databases for systematic reviews: added value or diminishing returns?C Stevinson
Department of Exercise and Health Sciences, Centre for Sport, Exercise and Health, University of Bristol, Tyndall Avenue, Bristol BS8 1TP, UK
Complement Ther Med 12:228-32. 2004..To explore whether searching specialised bibliographic databases identified additional relevant papers to those located by a Medline search for a systematic review of exercise therapy...
Gamma-glutamyltransferase is associated with incident vascular events independently of alcohol intake: analysis of the British Women's Heart and Health Study and Meta-AnalysisAbigail Fraser
Department of Social Medicine, University of Bristol, Canynge Hall, Whiteladies Rd, Bristol BS8 2PR, UK
Arterioscler Thromb Vasc Biol 27:2729-35. 2007..Alanine aminotransferase (ALT) is the enzyme most closely associated with liver fat content...
The associations between height components (leg and trunk length) and adult levels of liver enzymesA Fraser
Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
J Epidemiol Community Health 62:48-53. 2008....
Challenges and novel approaches in the epidemiological study of early life influences on later diseaseGeorge Davey Smith
Department of Social Medicine, University of Bristol, Canynge Hall, Bristol, UK
Adv Exp Med Biol 646:1-14. 2009..Other epidemiological strategies are briefly reviewed. It is concluded that the naïve acceptance of findings utilising conventional epidemiological methods in this setting is misplaced...
Changing epidemiology of bacterial meningitis among adults in England and Wales 1991-2002A B Gjini
Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, UK
Epidemiol Infect 134:567-9. 2006..Improvements in clinical management, childhood vaccination programmes and the re-emergence of tuberculosis are likely to be drivers of these changes...
Rurality, deprivation, and excess winter mortality: an ecological studyD A Lawlor
Department of Social Medicine, University of Bristol, Bristol UK
J Epidemiol Community Health 56:373-4. 2002
Research Grants
- Maternal overnutrition and offspring fat mass, metabolic and vascular function.Debbie Lawlor; Fiscal Year: 2007....
- Maternal overnutrition and offspring fat mass, metabolic and vascular function.Debbie Lawlor; Fiscal Year: 2009....
