Mark Larance

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. pmc Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3
    Mark Larance
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, Australia
    Mol Cell Proteomics 9:682-94. 2010
  2. ncbi request reprint A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160
    Georg Ramm
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, NSW, Australia
    J Biol Chem 281:29174-80. 2006
  3. ncbi request reprint CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes
    Ming Fai Yip
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
    Cell Metab 8:384-98. 2008
  4. pmc Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin
    Alexander F Rowland
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia
    Mol Cell Biol 31:4789-800. 2011
  5. ncbi request reprint The GLUT4 code
    Mark Larance
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Sydney 2010, Australia
    Mol Endocrinol 22:226-33. 2008
  6. pmc Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein
    Tilman Brummer
    Cancer Research Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    EMBO J 27:2305-16. 2008
  7. doi request reprint Quantitative proteomic analysis of the adipocyte plasma membrane
    Matthew J Prior
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia
    J Proteome Res 10:4970-82. 2011
  8. ncbi request reprint Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking
    Mark Larance
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, Australia
    J Biol Chem 280:37803-13. 2005
  9. pmc Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity
    Kyle L Hoehn
    Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Cell Metab 11:70-6. 2010

Collaborators

Detail Information

Publications9

  1. pmc Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3
    Mark Larance
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, Australia
    Mol Cell Proteomics 9:682-94. 2010
    ..These data highlight an important new arm of the insulin signaling cascade in the regulation of mRNA utilization...
  2. ncbi request reprint A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160
    Georg Ramm
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, NSW, Australia
    J Biol Chem 281:29174-80. 2006
    ..These data show that the insulin-dependent association of 14-3-3 with AS160 plays an important role in GLUT4 trafficking in adipocytes...
  3. ncbi request reprint CaMKII-mediated phosphorylation of the myosin motor Myo1c is required for insulin-stimulated GLUT4 translocation in adipocytes
    Ming Fai Yip
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia
    Cell Metab 8:384-98. 2008
    ..These data suggest that insulin regulates Myo1c function via CaMKII-dependent phosphorylation, and these events play a role in insulin-regulated GLUT4 trafficking in adipocytes likely involving Myo1c motor activity...
  4. pmc Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin
    Alexander F Rowland
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, New South Wales 2010, Australia
    Mol Cell Biol 31:4789-800. 2011
    ....
  5. ncbi request reprint The GLUT4 code
    Mark Larance
    Diabetes and Obesity Research Program, Garvan Institute of Medical Research, Sydney 2010, Australia
    Mol Endocrinol 22:226-33. 2008
    ..Many are now taking on this challenge...
  6. pmc Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein
    Tilman Brummer
    Cancer Research Program, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
    EMBO J 27:2305-16. 2008
    ..This represents a novel regulatory mechanism with implications for diverse tyrosine kinase signalling systems...
  7. doi request reprint Quantitative proteomic analysis of the adipocyte plasma membrane
    Matthew J Prior
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia
    J Proteome Res 10:4970-82. 2011
    ..Together these studies provide a wealth of potential therapeutic targets for the manipulation of adipocyte function and a valuable resource for metabolic research and PM biology...
  8. ncbi request reprint Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking
    Mark Larance
    Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, Australia
    J Biol Chem 280:37803-13. 2005
    ..These findings support an important role for AS160 in the insulin regulated trafficking of GLUT4...
  9. pmc Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity
    Kyle L Hoehn
    Garvan Institute of Medical Research, Darlinghurst, NSW, Australia
    Cell Metab 11:70-6. 2010
    ..We conclude that negative energy balance is a prerequisite for weight reduction, and increased fatty acid oxidation per se has little, if any, effect to reduce adiposity...