Matthew A Lambon Ralph

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. doi request reprint Finite case series or infinite single-case studies? Comments on "Case series investigations in cognitive neuropsychology" by Schwartz and Dell (2010)
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, UK
    Cogn Neuropsychol 28:466-74; discussion 515-20. 2011
  2. doi request reprint Predicting the outcome of anomia therapy for people with aphasia post CVA: both language and cognitive status are key predictors
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Oxford Road, Manchester, UK
    Neuropsychol Rehabil 20:289-305. 2010
  3. pmc Different impairments of semantic cognition in semantic dementia and semantic aphasia: evidence from the non-verbal domain
    Faye Corbett
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, Manchester, UK
    Brain 132:2593-608. 2009
  4. ncbi request reprint Neural basis of category-specific semantic deficits for living things: evidence from semantic dementia, HSVE and a neural network model
    Matthew A Lambon Ralph
    School of Psychological Sciences, University of Manchester, Manchester, UK
    Brain 130:1127-37. 2007
  5. doi request reprint Taking both sides: do unilateral anterior temporal lobe lesions disrupt semantic memory?
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Zochonis Building, Brunswick Street, Manchester, M13 9PL, UK
    Brain 133:3243-55. 2010
  6. doi request reprint Generalization and differentiation in semantic memory: insights from semantic dementia
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, UK
    Ann N Y Acad Sci 1124:61-76. 2008
  7. doi request reprint Conceptual knowledge is underpinned by the temporal pole bilaterally: convergent evidence from rTMS
    Matthew A Lambon Ralph
    University of Manchester, UK
    Cereb Cortex 19:832-8. 2009
  8. pmc Semantic memory is impaired in patients with unilateral anterior temporal lobe resection for temporal lobe epilepsy
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, Manchester M13 9PL, UK
    Brain 135:242-58. 2012
  9. doi request reprint Elucidating the nature of deregulated semantic cognition in semantic aphasia: evidence for the roles of prefrontal and temporo-parietal cortices
    Krist A Noonan
    University of Manchester, Manchester, UK
    J Cogn Neurosci 22:1597-613. 2010
  10. ncbi request reprint Surface dyslexia in semantic dementia: a comparison of the influence of consistency and regularity
    Elizabeth Jefferies
    Department of Psychology, University of Manchester, UK
    Neurocase 10:290-9. 2004

Detail Information

Publications69

  1. doi request reprint Finite case series or infinite single-case studies? Comments on "Case series investigations in cognitive neuropsychology" by Schwartz and Dell (2010)
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, UK
    Cogn Neuropsychol 28:466-74; discussion 515-20. 2011
    ..We conclude by suggesting that, alongside other neuroscience techniques, case-series cognitive neuropsychology provides a crucial contribution to the future of clinical and cognitive neuroscience...
  2. doi request reprint Predicting the outcome of anomia therapy for people with aphasia post CVA: both language and cognitive status are key predictors
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Oxford Road, Manchester, UK
    Neuropsychol Rehabil 20:289-305. 2010
    ..Pre-treatment naming ability also predicted gain after the anomia therapy. When combined, both cognitive and language (naming or phonological) skills were found to be independent predictors of therapy outcome...
  3. pmc Different impairments of semantic cognition in semantic dementia and semantic aphasia: evidence from the non-verbal domain
    Faye Corbett
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, Manchester, UK
    Brain 132:2593-608. 2009
    ..This study provides converging evidence for qualitatively different impairments of semantic cognition in SD and SA, and uniquely demonstrates this pattern in a non-verbal expressive domain-object use...
  4. ncbi request reprint Neural basis of category-specific semantic deficits for living things: evidence from semantic dementia, HSVE and a neural network model
    Matthew A Lambon Ralph
    School of Psychological Sciences, University of Manchester, Manchester, UK
    Brain 130:1127-37. 2007
    ..Three novel predictions from this model were tested and confirmed, thereby adding weight to the hypothesis that both type and distribution of pathology can be critical in producing neuropsychological phenomena...
  5. doi request reprint Taking both sides: do unilateral anterior temporal lobe lesions disrupt semantic memory?
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Zochonis Building, Brunswick Street, Manchester, M13 9PL, UK
    Brain 133:3243-55. 2010
    ....
  6. doi request reprint Generalization and differentiation in semantic memory: insights from semantic dementia
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, UK
    Ann N Y Acad Sci 1124:61-76. 2008
    ..The article describes a comprehensive array of under- and overgeneralization errors by patients with SD when engaged in receptive and expressive verbal and nonverbal tasks and everyday behaviors...
  7. doi request reprint Conceptual knowledge is underpinned by the temporal pole bilaterally: convergent evidence from rTMS
    Matthew A Lambon Ralph
    University of Manchester, UK
    Cereb Cortex 19:832-8. 2009
    ..The time required to make semantic decisions was slowed considerably, yet specifically, by this procedure. The results confirm that both TPs form a critical substrate within the neural network that supports conceptual knowledge...
  8. pmc Semantic memory is impaired in patients with unilateral anterior temporal lobe resection for temporal lobe epilepsy
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, Manchester M13 9PL, UK
    Brain 135:242-58. 2012
    ....
  9. doi request reprint Elucidating the nature of deregulated semantic cognition in semantic aphasia: evidence for the roles of prefrontal and temporo-parietal cortices
    Krist A Noonan
    University of Manchester, Manchester, UK
    J Cogn Neurosci 22:1597-613. 2010
    ....
  10. ncbi request reprint Surface dyslexia in semantic dementia: a comparison of the influence of consistency and regularity
    Elizabeth Jefferies
    Department of Psychology, University of Manchester, UK
    Neurocase 10:290-9. 2004
    ..2001) and the triangle model (Plaut et al., 1996). It is argued that the triangle model provides a more straightforward account of the relationship between word comprehension and consistency effects in reading...
  11. ncbi request reprint The natural history of late-stage "pure" semantic dementia
    Elizabeth Jefferies
    School of Psychological Sciences, University of Manchester, Oxford Road, Manchester, M13 9PL, UK
    Neurocase 12:1-14. 2006
    ..These findings are discussed in terms of theories that posit strong interactivity between phonology and semantics...
  12. pmc Semantic memory is key to binding phonology: converging evidence from immediate serial recall in semantic dementia and healthy participants
    Paul Hoffman
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, Zochonis Building, University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Neuropsychologia 47:747-60. 2009
    ....
  13. doi request reprint When does less yield more? The impact of severity upon implicit recognition in pure alexia
    Daniel J Roberts
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, UK
    Neuropsychologia 48:2437-46. 2010
    ..These results also go some way towards explaining the individual variation in the presence of this effect observed across previous case-study investigations in the literature...
  14. doi request reprint Semantic diversity: a measure of semantic ambiguity based on variability in the contextual usage of words
    Paul Hoffman
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, Zochonis Building, Oxford Road, Manchester M13 9PL, UK
    Behav Res Methods 45:718-30. 2013
    ..SemD values for over 30,000 English words are provided as supplementary materials. ..
  15. doi request reprint Demonstrating the qualitative differences between semantic aphasia and semantic dementia: a novel exploration of nonverbal semantic processing
    Krist A Noonan
    School of Psychological Sciences, University of Manchester, Manchester, UK
    Behav Neurol 26:7-20. 2013
    ..In contrast, SD patients performed poorly because their degraded knowledge did not allow the fine-grained distinctions required to complete the task...
  16. pmc Coherent concepts are computed in the anterior temporal lobes
    Matthew A Lambon Ralph
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester M13 9PL, United Kingdom
    Proc Natl Acad Sci U S A 107:2717-22. 2010
    ....
  17. ncbi request reprint Semantic impairment in stroke aphasia versus semantic dementia: a case-series comparison
    Elizabeth Jefferies
    School of Psychological Sciences, University of Manchester, Manchester, UK
    Brain 129:2132-47. 2006
    ....
  18. pmc The role of the anterior temporal lobes in the comprehension of concrete and abstract words: rTMS evidence
    Gorana Pobric
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, UK
    Cortex 45:1104-10. 2009
    ..These results confirm that both TPs make a critical contribution to semantic processing, even for abstract concepts that do not have strong sensory representations...
  19. pmc Category-specific versus category-general semantic impairment induced by transcranial magnetic stimulation
    Gorana Pobric
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester M13 9PL, UK
    Curr Biol 20:964-8. 2010
    ....
  20. doi request reprint Be concrete to be comprehended: consistent imageability effects in semantic dementia for nouns, verbs, synonyms and associates
    Paul Hoffman
    Neuroscience and Aphasia Research Unit NARU, University of Manchester, Manchester, UK
    Cortex 49:1206-18. 2013
    ..Concrete words succumb less quickly by virtue of their richer and more detailed semantic representations...
  21. ncbi request reprint The treatment of anomia using errorless learning
    Joanne K Fillingham
    Department of Psychology, The University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Neuropsychol Rehabil 16:129-54. 2006
    ..It is probable that these factors are essential cognitive components for providing effective monitoring and feedback systems to a more general learning mechanism...
  22. doi request reprint Ventrolateral prefrontal cortex plays an executive regulation role in comprehension of abstract words: convergent neuropsychological and repetitive TMS evidence
    Paul Hoffman
    Neuroscience and Aphasia Research Unit, University of Manchester, Manchester M13 9PL, UK
    J Neurosci 30:15450-6. 2010
    ..Regulation is less important for concrete words because their meanings are constrained by their physical referents and do not tend to vary with context...
  23. ncbi request reprint What underlies the neuropsychological pattern of irregular > regular past-tense verb production?
    Matthew A Lambon Ralph
    School of Psychological Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom
    Brain Lang 93:106-19. 2005
    ..The phonological nature of the factors that correlated with verb-inflection performance emphasises the role of a phonological deficit in the observed pattern of irregular > regular...
  24. doi request reprint Fundamental deficits of auditory perception in Wernicke's aphasia
    Holly Robson
    Neuroscience and Aphasia Research Unit, University of Manchester, UK Psychology and Clinical Language Sciences, University of Reading, UK
    Cortex 49:1808-22. 2013
    ....
  25. doi request reprint Shapes, scents and sounds: quantifying the full multi-sensory basis of conceptual knowledge
    Paul Hoffman
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, Zochonis Building, University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Neuropsychologia 51:14-25. 2013
    ..Multi-modal ratings for 160 objects are provided as supplementary materials...
  26. doi request reprint Convergent connectivity and graded specialization in the rostral human temporal lobe as revealed by diffusion-weighted imaging probabilistic tractography
    Richard J Binney
    University of Manchester, UK
    J Cogn Neurosci 24:1998-2014. 2012
    ....
  27. doi request reprint Both the middle temporal gyrus and the ventral anterior temporal area are crucial for multimodal semantic processing: distortion-corrected fMRI evidence for a double gradient of information convergence in the temporal lobes
    Maya Visser
    University of Manchester, Manchester, UK
    J Cogn Neurosci 24:1766-78. 2012
    ..Additional planned, ROI analyses show that this result follows from two principal axes of convergence in the temporal lobe: both lateral (toward MTG) and longitudinal (toward the anterior temporal lobe)...
  28. doi request reprint How intensive does anomia therapy for people with aphasia need to be?
    Karen Sage
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, UK
    Neuropsychol Rehabil 21:26-41. 2011
    ..For the majority of people with aphasia post-stroke, both intense and non-intense therapy for anomia leads to improved naming performance. Retention at one-month post therapy is relatively superior after non-intensive therapy...
  29. doi request reprint Reverse concreteness effects are not a typical feature of semantic dementia: evidence for the hub-and-spoke model of conceptual representation
    Paul Hoffman
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester M13 9PL, UK
    Cereb Cortex 21:2103-12. 2011
    ..These factors account for the variability in previous studies and indicate that reverse concreteness effects are not common in SD...
  30. doi request reprint Lichtheim 2: synthesizing aphasia and the neural basis of language in a neurocomputational model of the dual dorsal-ventral language pathways
    Taiji Ueno
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester M139PL, UK
    Neuron 72:385-96. 2011
    ....
  31. doi request reprint The anterior temporal lobes support residual comprehension in Wernicke's aphasia
    Holly Robson
    1 Neuroscience and Aphasia Research Unit, School Psychological Sciences, University of Manchester, UK
    Brain 137:931-43. 2014
    ..Overall, the results provide support for models in which the anterior temporal lobes are crucial for multimodal semantic processing and that these regions may be accessed without support from classic posterior comprehension regions. ..
  32. doi request reprint What's in a word? A parametric study of semantic influences on visual word recognition
    Gemma A L Evans
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, Zochonis Building, University of Manchester, Brunswick Street, Manchester M13 9PL, England, UK
    Psychon Bull Rev 19:325-31. 2012
    ..These findings provide a clear illustration of the flexible use of semantic information to support normal visual word recognition...
  33. doi request reprint Overview and ways forward for future research
    Paul Conroy
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, Manchester, UK
    Neuropsychol Rehabil 22:319-28. 2012
    ..These studies delineate some of the critical theoretical-clinical issues through which we might optimise learning and rehabilitative efforts more fully...
  34. doi request reprint Staging of the cognitive decline in Alzheimer's disease: insights from a detailed neuropsychological investigation of mild cognitive impairment and mild Alzheimer's disease
    Stephen F Carter
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, UK
    Int J Geriatr Psychiatry 27:423-32. 2012
    ..The current investigation attempted to elucidate the appearance of additional cognitive deficits in the non-episodic domains and to understand these deficits with respect to the known pathological staging of AD...
  35. doi request reprint Using phonemic cueing of spontaneous naming to predict item responsiveness to therapy for anomia in aphasia
    Paul J Conroy
    Neuroscience and Aphasia Research Unit, University of Manchester, Manchester, UK
    Arch Phys Med Rehabil 93:S53-60. 2012
    ..The relationship between this form of cueing and the outcome of naming therapy is of particular interest given that cueing is an established research and clinical tool within aphasiology, and is commonly used to probe naming performance...
  36. ncbi request reprint Lexical and semantic influences on item and order memory in immediate serial recognition: evidence from a novel task
    Elizabeth Jefferies
    University of Manchester, Manchester, UK
    Q J Exp Psychol (Hove) 59:949-64. 2006
    ..These results point to strong similarities between immediate serial recall and recognition. Lexical/semantic knowledge may contribute to phonological stability in both tasks...
  37. ncbi request reprint Using parallel distributed processing models to simulate phonological dyslexia: the key role of plasticity-related recovery
    Stephen R Welbourne
    School of Psychological Sciences, University of Manchester, Oxford Road, Manchester, UK
    J Cogn Neurosci 19:1125-39. 2007
    ..This result supports the view that plasticity-related changes should be a significant factor in our understanding of chronic behavioral dissociations...
  38. doi request reprint SD-squared revisited: reply to Coltheart, Tree, and Saunders (2010)
    Anna M Woollams
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, Zochonis Building, University of Manchester, Brunswick Street, Manchester M139PL, England
    Psychol Rev 117:273-81; discussion 282-3. 2010
    ..Moreover, we argue that the connectionist triangle model account has substantially greater explanatory and predictive power than the DRC account...
  39. doi request reprint The anterior temporal lobe semantic hub is a part of the language neural network: selective disruption of irregular past tense verbs by rTMS
    Rachel Holland
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, UK
    Cereb Cortex 20:2771-5. 2010
    ..When combined with other evidence, these results confirm that the ATL semantic hub is a key component of the neural network for language...
  40. ncbi request reprint The role of the temporal lobe semantic system in number knowledge: evidence from late-stage semantic dementia
    Elizabeth Jefferies
    Department of Psychology, University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Neuropsychologia 43:887-905. 2005
    ....
  41. doi request reprint Solving the paradox of the equipotential and modular brain: a neurocomputational model of stroke vs. slow-growing glioma
    James L Keidel
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences Zochonis Building, University of Manchester, Brunswick Street, Manchester M139PL, UK
    Neuropsychologia 48:1716-24. 2010
    ..This work provides support for a neo-Lashleyan view of cortical organization...
  42. ncbi request reprint Mimicking aphasic semantic errors in normal speech production: evidence from a novel experimental paradigm
    Catherine Hodgson
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, Zochonis Building, University of Manchester, Manchester, UK
    Brain Lang 104:89-101. 2008
    ..A. (2006). Semantic impairment in stoke aphasia vs. semantic dementia: A case-series comparison. Brain, 129, 2132-2147]. Further implications for theories of semantic cognition and models of speech processing are discussed...
  43. pmc Explaining semantic short-term memory deficits: evidence for the critical role of semantic control
    Paul Hoffman
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, UK
    Neuropsychologia 49:368-81. 2011
    ..Instead, we argue that semantic STM patients occupy the mildest end of spectrum of semantic control disorders...
  44. pmc Remembering 'zeal' but not 'thing': reverse frequency effects as a consequence of deregulated semantic processing
    Paul Hoffman
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, UK
    Neuropsychologia 49:580-4. 2011
    ..In contrast, LF words are associated with more stable patterns of activation because similar semantic information is activated whenever they are encountered...
  45. pmc Using in vivo probabilistic tractography to reveal two segregated dorsal 'language-cognitive' pathways in the human brain
    Lauren L Cloutman
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, UK Electronic address
    Brain Lang 127:230-40. 2013
    ....
  46. pmc The role of sleep spindles and slow-wave activity in integrating new information in semantic memory
    Jakke Tamminen
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester M13 9PL, United Kingdom, and Department of Psychology, Royal Holloway, University of London, Egham TW20 0EX, United Kingdom
    J Neurosci 33:15376-81. 2013
    ..These findings provide the first evidence that spindles and slow-wave activity mediate integration of new information into existing semantic networks. ..
  47. pmc The neural basis of conceptual-emotional integration and its role in major depressive disorder
    Sophie Green
    a Neuroscience and Aphasia Research Unit, School of Psychological Sciences, The University of Manchester and Manchester Academic Health Sciences Centre, Manchester, UK
    Soc Neurosci 8:417-33. 2013
    ....
  48. ncbi request reprint Guilt-selective functional disconnection of anterior temporal and subgenual cortices in major depressive disorder
    Sophie Green
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, The University of Manchester and Manchester Academic Health Sciences Centre, Manchester, England
    Arch Gen Psychiatry 69:1014-21. 2012
    ..Despite its psychopathological importance, the functional neuroanatomy of guilt in MDD is unknown...
  49. doi request reprint The variation of function across the human insula mirrors its patterns of structural connectivity: evidence from in vivo probabilistic tractography
    Lauren L Cloutman
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, UK
    Neuroimage 59:3514-21. 2012
    ....
  50. doi request reprint Relearning in semantic dementia reflects contributions from both medial temporal lobe episodic and degraded neocortical semantic systems: evidence in support of the complementary learning systems theory
    Emily J Mayberry
    Neuroscience and Aphasia Research Unit NARU, School of Psychological Sciences, University of Manchester, Manchester, UK
    Neuropsychologia 49:3591-8. 2011
    ..Because of neocortical damage to the anterior temporal lobes, relearning is disordered with a characteristic pattern of under- and over-generalisation...
  51. pmc The anterior temporal lobes are critically involved in acquiring new conceptual knowledge: evidence for impaired feature integration in semantic dementia
    Paul Hoffman
    Neuroscience and Aphasia Research Unit NARU, University of Manchester, UK Electronic address
    Cortex 50:19-31. 2014
    ..This explains the central role of this region in conceptual representation and the catastrophic breakdown of concepts in semantic dementia. ..
  52. pmc Efficient visual object and word recognition relies on high spatial frequency coding in the left posterior fusiform gyrus: evidence from a case-series of patients with ventral occipito-temporal cortex damage
    Daniel J Roberts
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, UK
    Cereb Cortex 23:2568-80. 2013
    ..These results suggest that the patients' dual reading and non-orthographic recognition impairments have a common underlying mechanism and reflect the loss of high spatial frequency visual information normally coded in the left pFG...
  53. doi request reprint Revealing and quantifying the impaired phonological analysis underpinning impaired comprehension in Wernicke's aphasia
    Holly Robson
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester, Manchester, United Kingdom
    Neuropsychologia 50:276-88. 2012
    ....
  54. ncbi request reprint Lateralization of ventral and dorsal auditory-language pathways in the human brain
    Geoffrey J M Parker
    Imaging Science and Biomedical Engineering, University of Manchester, Manchester M13 9PT, UK
    Neuroimage 24:656-66. 2005
    ..The connections are stronger in the dominant hemisphere, in agreement with previous studies of functional lateralization of auditory-language processing...
  55. doi request reprint The role of plasticity-related functional reorganization in the explanation of central dyslexias
    Stephen R Welbourne
    School of Psychological Sciences, University of Manchester, Manchester, UK
    Cogn Neuropsychol 28:65-108. 2011
    ..In all cases, the DOL changed significantly in the recovery period, suggesting that postmorbid functional reorganization is important in understanding behaviour in chronic-stage patients...
  56. doi request reprint Wernicke's aphasia reflects a combination of acoustic-phonological and semantic control deficits: a case-series comparison of Wernicke's aphasia, semantic dementia and semantic aphasia
    Holly Robson
    Neuroscience and Aphasia Research Unit NARU, University of Manchester, Manchester, UK
    Neuropsychologia 50:266-75. 2012
    ..These results deviate from traditional accounts which emphasise a single impairment and, instead, implicate two deficits underlying the comprehension disorder in WA...
  57. pmc Connectivity-based structural and functional parcellation of the human cortex using diffusion imaging and tractography
    Lauren L Cloutman
    Neuroscience and Aphasia Research Unit, School of Psychological Sciences, University of Manchester Manchester, UK
    Front Neuroanat 6:34. 2012
    ..As such, it is of vital importance to continue to improve the accuracy of the methodology and to extend its potential applications in the study of cognition in neurological health and disease...
  58. ncbi request reprint The relationship between phonological and morphological deficits in Broca's aphasia: further evidence from errors in verb inflection
    Natalie Braber
    University of Manchester, UK
    Brain Lang 92:278-87. 2005
    ..These results are consistent with the notion that the patients' relatively greater difficulty with regular past tenses reflects a phonological impairment that is sensitive to the complexity of spoken forms...
  59. ncbi request reprint Distinct patterns of olfactory impairment in Alzheimer's disease, semantic dementia, frontotemporal dementia, and corticobasal degeneration
    Simona Luzzi
    Department of Neuroscience, University of Ancona, Italy
    Neuropsychologia 45:1823-31. 2007
    ..The findings add further insights into the nature of the semantic deficit in SD by exploring a hitherto neglected modality and may have relevance in explaining the altered eating habits commonly associated with SD...
  60. pmc Dissociating stimulus-driven semantic and phonological effect during reading and naming
    Andrea Mechelli
    Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 28:205-17. 2007
    ..In conclusion, this study dissociates the effects of semantic and phonological relatedness between successive items during reading and naming aloud...
  61. ncbi request reprint Unlocking the nature of the phonological-deep dyslexia continuum: the keys to reading aloud are in phonology and semantics
    Jenni Crisp
    North Tyneside Primary Care Trust, UK
    J Cogn Neurosci 18:348-62. 2006
    ..This proposal was supported by eliciting the symptoms of deep-phonological dyslexia in nonreading tasks...
  62. ncbi request reprint When objects lose their meaning: what happens to their use?
    Sasha Bozeat
    MRC Cognition and Brain Sciences Unit, Cambridge, England
    Cogn Affect Behav Neurosci 2:236-51. 2002
    ..Finally, despite good performance on tests of mechanical problem solving, the patients showed very little evidence of employing these skills in their interactions with real objects...
  63. ncbi request reprint Homogeneity and heterogeneity in mild cognitive impairment and Alzheimer's disease: a cross-sectional and longitudinal study of 55 cases
    Matthew A Lambon Ralph
    MRC Cognition and Brain Sciences Unit, Addenbrooke s Hospital, Cambridge, UK
    Brain 126:2350-62. 2003
    ..Although such cases may mimic more focal lobar degenerative conditions, patients with atypical Alzheimer's disease have pronounced episodic memory impairments, suggesting amnesia as a critical diagnostic feature...
  64. ncbi request reprint Demonstrating a wordlikeness effect on nonword repetition performance in a conduction aphasic patient
    Akie Saito
    Department of Cognitive Psychology in Education, Graduate School of Education, Kyoto University, Yoshida Honmachi, Sakyo ku, Kyoto 606 8501, Japan
    Brain Lang 85:222-30. 2003
    ..We conclude that she had difficulty in maintaining stable phonological representations of verbal materials in the output buffer...
  65. ncbi request reprint Dissociating reading processes on the basis of neuronal interactions
    Andrea Mechelli
    Functional Imaging Laboratory, Wellcome Department of Imaging Neuroscience, Institute of Neurology, London, UK
    J Cogn Neurosci 17:1753-65. 2005
    ..The present investigation is the first to identify distinct neuronal mechanisms for semantic and phonological contributions to reading...
  66. ncbi request reprint A category-specific advantage for numbers in verbal short-term memory: evidence from semantic dementia
    Elizabeth Jefferies
    University of Bristol, Bristol, UK
    Neuropsychologia 42:639-60. 2004
    ....
  67. ncbi request reprint Structure and deterioration of semantic memory: a neuropsychological and computational investigation
    Timothy T Rogers
    Medical Research Council Cognition and Brain Sciences Unit, Cambridge, UK
    Psychol Rev 111:205-35. 2004
    ..Data from 4 well-known semantic tasks revealed consistent patterns that find a ready explanation in the model. The relationship between the model and related theories of semantic representation is discussed...
  68. ncbi request reprint "Presemantic" cognition in semantic dementia: six deficits in search of an explanation
    Karalyn Patterson
    MRC Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, UK
    J Cogn Neurosci 18:169-83. 2006
    ..We argue that these results cannot be explained as associated but unrelated deficits but instead are a principled consequence of a primary semantic impairment...
  69. ncbi request reprint Semantic feature knowledge and picture naming in dementia of Alzheimer's type: a new approach
    Peter Garrard
    Institute of Cognitive Neuroscience, Alexandra House, 17 Queen Square, London WC1N 3AR, UK
    Brain Lang 93:79-94. 2005
    ..These findings are discussed in the context of contemporary cognitive and computational models of semantic memory organisation...