A Lalvani

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Impact of a T cell-based blood test for tuberculosis infection on clinical decision-making in routine practice
    Sarah Gooding
    Tuberculosis Immunology Group, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    J Infect 54:e169-74. 2007
  2. ncbi Rapid effector function in CD8+ memory T cells
    A Lalvani
    Molecular Immunology Group, Institute of Molecular Medicine, Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    J Exp Med 186:859-65. 1997
  3. ncbi Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians
    A Lalvani
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Infect Dis 183:469-77. 2001
  4. ncbi Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells
    A Lalvani
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Am J Respir Crit Care Med 163:824-8. 2001
  5. ncbi Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells
    A Lalvani
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Lancet 357:2017-21. 2001
  6. ncbi Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment
    A A Pathan
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Immunol 167:5217-25. 2001
  7. ncbi Cytotoxic T-lymphocyte epitopes for HLA-B53 and other HLA types in the malaria vaccine candidate liver-stage antigen 3
    M Aidoo
    Molecular Immunology Group, Institute of Molecular Medicine, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Infect Immun 68:227-32. 2000
  8. ncbi Osteomyelitis of the humerus complicating BCG vaccination
    S Segal
    Dept of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Arch Dis Child 91:244. 2006
  9. ncbi Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics
    P J Cockle
    TB Research Group, Department of Bacterial Diseases, Veterinary Laboratories Agency-Weybridge, New Haw, Addlestone, United Kingdom
    Infect Immun 70:6996-7003. 2002

Collaborators

Detail Information

Publications9

  1. ncbi Impact of a T cell-based blood test for tuberculosis infection on clinical decision-making in routine practice
    Sarah Gooding
    Tuberculosis Immunology Group, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    J Infect 54:e169-74. 2007
    ..Rapid determination of tuberculosis infection by ELISpot accelerated the diagnosis of tuberculosis, enabling early treatment initiation...
  2. ncbi Rapid effector function in CD8+ memory T cells
    A Lalvani
    Molecular Immunology Group, Institute of Molecular Medicine, Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    J Exp Med 186:859-65. 1997
    ..The phenotype of these cells, which persist at a low frequency long after recovery from an acute viral infection, suggests that they play a role in protective immunological memory...
  3. ncbi Enumeration of T cells specific for RD1-encoded antigens suggests a high prevalence of latent Mycobacterium tuberculosis infection in healthy urban Indians
    A Lalvani
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Infect Dis 183:469-77. 2001
    ..In contrast, of 40 mostly BCG-vaccinated, United Kingdom-resident healthy adults, none responded to either antigen. This study suggests an 80% prevalence of latent M. tuberculosis infection in urban India...
  4. ncbi Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells
    A Lalvani
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    Am J Respir Crit Care Med 163:824-8. 2001
    ..tuberculosis infection and BCG vaccination. This capability may facilitate tuberculosis control in nonendemic regions...
  5. ncbi Enhanced contact tracing and spatial tracking of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells
    A Lalvani
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Lancet 357:2017-21. 2001
    ..With an enzyme-linked immunospot (ELISPOT) assay for interferon gamma, we have identified ESAT-6-specific T cells as an accurate marker of M tuberculosis infection...
  6. ncbi Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment
    A A Pathan
    Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom
    J Immunol 167:5217-25. 2001
    ..tuberculosis in vivo. Such findings may assist in the design and evaluation of novel tuberculosis vaccine candidates...
  7. ncbi Cytotoxic T-lymphocyte epitopes for HLA-B53 and other HLA types in the malaria vaccine candidate liver-stage antigen 3
    M Aidoo
    Molecular Immunology Group, Institute of Molecular Medicine, Nuffield Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
    Infect Immun 68:227-32. 2000
    ..These findings emphasize the diversity of P. falciparum antigens recognized by CD8(+) T cells in humans and support the inclusion of components from several antigens in new CTL-inducing vaccines against malaria...
  8. ncbi Osteomyelitis of the humerus complicating BCG vaccination
    S Segal
    Dept of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Arch Dis Child 91:244. 2006
  9. ncbi Identification of novel Mycobacterium tuberculosis antigens with potential as diagnostic reagents or subunit vaccine candidates by comparative genomics
    P J Cockle
    TB Research Group, Department of Bacterial Diseases, Veterinary Laboratories Agency-Weybridge, New Haw, Addlestone, United Kingdom
    Infect Immun 70:6996-7003. 2002
    ..In particular, eight highly immunogenic antigens were identified whose potentials as diagnostic reagents or as subunit vaccines warrant further study (Rv1983, Rv1986, Rv3872, Rv3873, Rv3878, Rv3879c, Rv1979c, and Rv1769)...