D L Lafontaine

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?
    D L Lafontaine
    Institute of Cell and Molecular Biology, The University of Edinburgh, Scotland
    Mol Cell Biol 18:2360-70. 1998
  2. pmc Nop58p is a common component of the box C+D snoRNPs that is required for snoRNA stability
    D L Lafontaine
    Institute of Cell and Molecular Biology, The University of Edinburgh, Scotland
    RNA 5:455-67. 1999
  3. pmc Synthesis and assembly of the box C+D small nucleolar RNPs
    D L Lafontaine
    ICMB, The University of Edinburgh, Edinburgh EH9 3JR, Scotland
    Mol Cell Biol 20:2650-9. 2000
  4. pmc The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase
    D L Lafontaine
    Institute of Cell and Molecular Biology, University of Edinburgh, King s Buildings, Edinburgh EH9 3JR, UK
    Genes Dev 12:527-37. 1998
  5. pmc Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3
    A Colley
    Institute of Cell and Molecular Biology, The University of Edinburgh, Edinburgh EH9 3JR, Scotland
    Mol Cell Biol 20:7238-46. 2000
  6. pmc Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA
    S Massenet
    Laboratoire de Maturation des ARN et Enzymologie Moleculaire, UMR7567 CNRS UHP, Faculte des Sciences, 54506 Vandoeuvre les Nancy Cedex, France
    Mol Cell Biol 19:2142-54. 1999
  7. pmc Box C/D small nucleolar RNA trafficking involves small nucleolar RNP proteins, nucleolar factors and a novel nuclear domain
    C Verheggen
    IGMM, IFR 24, UMR 5535 du CNRS, 34293 Montpellier Cedex 5, France
    EMBO J 20:5480-90. 2001
  8. ncbi The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis
    B Senger
    UPR no 9002 du CNRS, Institut de Biologie Moleculaire et Cellulaire du CNRS, 15 rue Rene Descartes, 67084 Strasbourg Cedex, France
    Mol Cell 8:1363-73. 2001

Collaborators

Detail Information

Publications8

  1. pmc Yeast 18S rRNA dimethylase Dim1p: a quality control mechanism in ribosome synthesis?
    D L Lafontaine
    Institute of Cell and Molecular Biology, The University of Edinburgh, Scotland
    Mol Cell Biol 18:2360-70. 1998
    ..This observation, which demonstrates that Dim1p is not directly required for pre-rRNA processing reactions, is consistent with the inhibition of pre-rRNA processing by an active repression system in the absence of Dim1p...
  2. pmc Nop58p is a common component of the box C+D snoRNPs that is required for snoRNA stability
    D L Lafontaine
    Institute of Cell and Molecular Biology, The University of Edinburgh, Scotland
    RNA 5:455-67. 1999
    ..Nop58p is the second common component of the box C+D snoRNPs to be identified and the first to be shown to be required for the stability and for the synthesis of these snoRNAs...
  3. pmc Synthesis and assembly of the box C+D small nucleolar RNPs
    D L Lafontaine
    ICMB, The University of Edinburgh, Edinburgh EH9 3JR, Scotland
    Mol Cell Biol 20:2650-9. 2000
    ..Unexpectedly, we found that Nop1p was specifically required for the synthesis and accumulation of box C+D snoRNAs processed from pre-mRNA introns and polycistronic transcripts...
  4. pmc The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase
    D L Lafontaine
    Institute of Cell and Molecular Biology, University of Edinburgh, King s Buildings, Edinburgh EH9 3JR, UK
    Genes Dev 12:527-37. 1998
    ..We conclude that Cbf5p is likely to be the rRNA Psi synthase and is an integral component of the box H + ACA class of snoRNPs, which function to target the enzyme to its site of action...
  5. pmc Dhr1p, a putative DEAH-box RNA helicase, is associated with the box C+D snoRNP U3
    A Colley
    Institute of Cell and Molecular Biology, The University of Edinburgh, Edinburgh EH9 3JR, Scotland
    Mol Cell Biol 20:7238-46. 2000
    ..We speculate that Dhr1p is targeted to the preribosomal particles by the U3-18S rRNA interaction and is required for the structural reorganization of the rRNA during formation of the central pseudoknot...
  6. pmc Pseudouridine mapping in the Saccharomyces cerevisiae spliceosomal U small nuclear RNAs (snRNAs) reveals that pseudouridine synthase pus1p exhibits a dual substrate specificity for U2 snRNA and tRNA
    S Massenet
    Laboratoire de Maturation des ARN et Enzymologie Moleculaire, UMR7567 CNRS UHP, Faculte des Sciences, 54506 Vandoeuvre les Nancy Cedex, France
    Mol Cell Biol 19:2142-54. 1999
    ..As depletion of rRNA-pseudouridine synthase Cbf5p had no effect on UsnRNA Psi content, formation of Psi residues in S. cerevisiae UsnRNAs is not dependent on the Cbf5p-snoRNA guided mechanism...
  7. pmc Box C/D small nucleolar RNA trafficking involves small nucleolar RNP proteins, nucleolar factors and a novel nuclear domain
    C Verheggen
    IGMM, IFR 24, UMR 5535 du CNRS, 34293 Montpellier Cedex 5, France
    EMBO J 20:5480-90. 2001
    ..We conclude that snoRNP assembly occurs either in the nucleoplasm, or during transit of snoRNAs through the NB, followed by routing of the complete snoRNP to functional sites of ribosome synthesis...
  8. ncbi The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis
    B Senger
    UPR no 9002 du CNRS, Institut de Biologie Moleculaire et Cellulaire du CNRS, 15 rue Rene Descartes, 67084 Strasbourg Cedex, France
    Mol Cell 8:1363-73. 2001
    ....