Henrik Kloverpris

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours
    Henrik Kloverpris
    Department of Virology, Statens Serum Institut, Denmark
    J Immunol Methods 356:70-8. 2010
  2. ncbi HIV control through a single nucleotide on the HLA-B locus
    Henrik N Kløverpris
    Department of Paediatrics, University of Oxford, Oxford, United Kingdom
    J Virol 86:11493-500. 2012
  3. ncbi HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control
    Henrik N Kloverpris
    Department of Paediatrics, University of Oxford, Peter Medawar Building, Oxford, United Kingdom
    J Virol 86:919-29. 2012
  4. ncbi HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703
    Philippa C Matthews
    Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom
    J Immunol 186:5675-86. 2011
  5. ncbi Sequence analysis of HIV-1 isolates from Guinea-Bissau: selection of vaccine epitopes relevant in both West African and European countries
    Lasse Vinner
    Virus Research and Development, Statens Serum Institut, Copenhagen, Denmark
    APMIS 119:487-97. 2011
  6. ncbi Induction of novel CD8+ T-cell responses during chronic untreated HIV-1 infection by immunization with subdominant cytotoxic T-lymphocyte epitopes
    Henrik Kloverpris
    Department of Virology, Statens Serum Institut, University of Copenhagen, Denmark
    AIDS 23:1329-40. 2009
  7. ncbi High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo
    Ruth Simmons
    Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
    J Infect Dis 203:1378-87. 2011

Collaborators

Detail Information

Publications7

  1. ncbi Dimethyl sulfoxide (DMSO) exposure to human peripheral blood mononuclear cells (PBMCs) abolish T cell responses only in high concentrations and following coincubation for more than two hours
    Henrik Kloverpris
    Department of Virology, Statens Serum Institut, Denmark
    J Immunol Methods 356:70-8. 2010
    ..In contrast, >2% for >2 hours compromises these responses. These data are relevant in the design of immunotherapies based on pulsing a large number of peptides onto antigen presenting cells prior to reinfusion...
  2. ncbi HIV control through a single nucleotide on the HLA-B locus
    Henrik N Kløverpris
    Department of Paediatrics, University of Oxford, Oxford, United Kingdom
    J Virol 86:11493-500. 2012
    ..This naturally controlled experiment represents perhaps the clearest demonstration of the direct impact of a particular HIV-specific CTL on disease control...
  3. ncbi HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control
    Henrik N Kloverpris
    Department of Paediatrics, University of Oxford, Peter Medawar Building, Oxford, United Kingdom
    J Virol 86:919-29. 2012
    ..These findings are consistent with HLA class I alleles mediating effective immune control of HIV through the number of p24 Gag-specific CD8(+) T-cell responses generated that can drive significant selection pressure on the virus...
  4. ncbi HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703
    Philippa C Matthews
    Department of Paediatrics, University of Oxford, Oxford OX1 3SY, United Kingdom
    J Immunol 186:5675-86. 2011
    ..In addition, these studies identify a factor contributing to different HIV disease outcomes in individuals expressing HLA-B*5703...
  5. ncbi Sequence analysis of HIV-1 isolates from Guinea-Bissau: selection of vaccine epitopes relevant in both West African and European countries
    Lasse Vinner
    Virus Research and Development, Statens Serum Institut, Copenhagen, Denmark
    APMIS 119:487-97. 2011
    ..Our results warrant testing of the selected vaccine epitopes in both geographic locations...
  6. ncbi Induction of novel CD8+ T-cell responses during chronic untreated HIV-1 infection by immunization with subdominant cytotoxic T-lymphocyte epitopes
    Henrik Kloverpris
    Department of Virology, Statens Serum Institut, University of Copenhagen, Denmark
    AIDS 23:1329-40. 2009
    ..To investigate the potential to induce additional cytotoxic T-lymphocyte (CTL) immunity during chronic HIV-1 infection...
  7. ncbi High frequency, sustained T cell responses to PARV4 suggest viral persistence in vivo
    Ruth Simmons
    Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom
    J Infect Dis 203:1378-87. 2011
    ..The interaction of PARV4 with the cellular immune system has not been described. Consequently, we investigated whether T cell responses to PARV4 could be detected in individuals exposed to blood-borne viruses...