Henry C Kitchener

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. pmc Survival from cancer of the ovary in England and Wales up to 2001
    H C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, Research Floor, St Mary s Hospital, Whitworth Park, Manchester, M13 0JH, UK
    Br J Cancer 99:S73-4. 2008
  2. pmc Survival from cancer of the uterine cervix in England and Wales up to 2001
    H C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, Research Floor, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, UK
    Br J Cancer 99:S63-4. 2008
  3. doi request reprint A comparison of HPV DNA testing and liquid based cytology over three rounds of primary cervical screening: extended follow up in the ARTISTIC trial
    Henry C Kitchener
    School of Cancer and enabling Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
    Eur J Cancer 47:864-71. 2011
  4. doi request reprint MAVARIC - a comparison of automation-assisted and manual cervical screening: a randomised controlled trial
    H C Kitchener
    School of Cancer and enabling Sciences, University of Manchester, St Mary s Hospital, Manchester, UK
    Health Technol Assess 15:iii-iv, ix-xi, 1-170. 2011
  5. doi request reprint Automation-assisted versus manual reading of cervical cytology (MAVARIC): a randomised controlled trial
    Henry C Kitchener
    School of Cancer and enabling Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
    Lancet Oncol 12:56-64. 2011
  6. doi request reprint HPV testing in combination with liquid-based cytology in primary cervical screening (ARTISTIC): a randomised controlled trial
    Henry C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, Manchester, UK
    Lancet Oncol 10:672-82. 2009
  7. pmc Survival from endometrial cancer in England and Wales up to 2001
    H C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, Research Floor, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, UK
    Br J Cancer 99:S68-9. 2008
  8. ncbi request reprint Human papillomavirus in cervical screening and vaccination
    Emma J Crosbie
    Academic Unit of Obstetrics and Gynaecology, University of Manchester, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, UK
    Clin Sci (Lond) 110:543-52. 2006
  9. doi request reprint Human papillomavirus and cervical cancer
    Emma J Crosbie
    Institute of Cancer Sciences, University of Manchester, Oxford Road, Manchester, UK
    Lancet 382:889-99. 2013
  10. doi request reprint Human papillomavirus as a target for management, prevention and therapy
    Emma J Crosbie
    Academic Unit of Obstetrics and Gynaecology, University of Manchester, St Mary s Hospital, Manchester, UK
    Int J Hyperthermia 28:478-88. 2012

Collaborators

Detail Information

Publications39

  1. pmc Survival from cancer of the ovary in England and Wales up to 2001
    H C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, Research Floor, St Mary s Hospital, Whitworth Park, Manchester, M13 0JH, UK
    Br J Cancer 99:S73-4. 2008
  2. pmc Survival from cancer of the uterine cervix in England and Wales up to 2001
    H C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, Research Floor, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, UK
    Br J Cancer 99:S63-4. 2008
  3. doi request reprint A comparison of HPV DNA testing and liquid based cytology over three rounds of primary cervical screening: extended follow up in the ARTISTIC trial
    Henry C Kitchener
    School of Cancer and enabling Sciences, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
    Eur J Cancer 47:864-71. 2011
    ..We wished to determine, through a further (third) round of screening in the ARTISTIC trial, the protection provided by a negative baseline HPV screen compared with that of cytology over a 6 year period...
  4. doi request reprint MAVARIC - a comparison of automation-assisted and manual cervical screening: a randomised controlled trial
    H C Kitchener
    School of Cancer and enabling Sciences, University of Manchester, St Mary s Hospital, Manchester, UK
    Health Technol Assess 15:iii-iv, ix-xi, 1-170. 2011
    ....
  5. doi request reprint Automation-assisted versus manual reading of cervical cytology (MAVARIC): a randomised controlled trial
    Henry C Kitchener
    School of Cancer and enabling Sciences, The University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
    Lancet Oncol 12:56-64. 2011
    ..In the Manual Assessment Versus Automated Reading In Cytology (MAVARIC) trial, we compared the accuracy of these techniques for the detection of underlying disease...
  6. doi request reprint HPV testing in combination with liquid-based cytology in primary cervical screening (ARTISTIC): a randomised controlled trial
    Henry C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, Manchester, UK
    Lancet Oncol 10:672-82. 2009
    ....
  7. pmc Survival from endometrial cancer in England and Wales up to 2001
    H C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, Research Floor, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, UK
    Br J Cancer 99:S68-9. 2008
  8. ncbi request reprint Human papillomavirus in cervical screening and vaccination
    Emma J Crosbie
    Academic Unit of Obstetrics and Gynaecology, University of Manchester, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, UK
    Clin Sci (Lond) 110:543-52. 2006
    ..For those generations of women already exposed to high-risk HPV infection, therapeutic vaccines may offer advantages over conventional treatment, although much work still needs to be done...
  9. doi request reprint Human papillomavirus and cervical cancer
    Emma J Crosbie
    Institute of Cancer Sciences, University of Manchester, Oxford Road, Manchester, UK
    Lancet 382:889-99. 2013
    ..If these prevention strategies can be implemented in developing countries, many thousands of lives could be saved. ..
  10. doi request reprint Human papillomavirus as a target for management, prevention and therapy
    Emma J Crosbie
    Academic Unit of Obstetrics and Gynaecology, University of Manchester, St Mary s Hospital, Manchester, UK
    Int J Hyperthermia 28:478-88. 2012
    ..In this review, the latest evidence supporting HPV as both a biomarker of risk for cervical cancer and a target for prophylactic and therapeutic vaccination is presented...
  11. doi request reprint Body mass index does not influence post-treatment survival in early stage endometrial cancer: results from the MRC ASTEC trial
    Emma J Crosbie
    Gynaecology Oncology Research Group, School of Cancer and enabling Sciences, University of Manchester, Manchester, UK
    Eur J Cancer 48:853-64. 2012
    ....
  12. pmc A semi-qualitative study of attitudes to vaccinating adolescents against human papillomavirus without parental consent
    Loretta Brabin
    Academic Unit of Obstetrics and Gynaecology, Research Floor, St, Mary s Hospital, Whitworth Park, Manchester, M13 0JH, UK
    BMC Public Health 7:20. 2007
    ..Under-16s in the UK have a right to confidential sexual health care without parental consent. We investigated parents' views on making available HPV vaccination to adolescent minors at sexual health clinics without parental consent...
  13. ncbi request reprint Chapter 7: Achievements and limitations of cervical cytology screening
    Henry C Kitchener
    Academic Unit of Obstetrics and Gynaecology, University of Manchester, St Mary s Hospital, Whitworth Park, Manchester, UK
    Vaccine 24:S3/63-70. 2006
    ..The increasing rate of human papillomavirus (HPV) testing and the prospect of prophylactic vaccination will change the way cervical cytology is used, possibly giving way to HPV testing as the primary test in secondary prevention...
  14. doi request reprint The second to fourth digit ratio (2D:4D) in women with and without human papillomavirus and cervical dysplasia
    Loretta Brabin
    Academic Unit of Obstetrics and Gynaecology, University of Manchester, Manchester M13 OJH, United Kingdom
    Am J Hum Biol 20:337-41. 2008
    ..A similar, nonsignificant trend was observed among women with a persistent HPV infection...
  15. ncbi request reprint Specific HIV protease inhibitors inhibit the ability of HPV16 E6 to degrade p53 and selectively kill E6-dependent cervical carcinoma cells in vitro
    Lynne Hampson
    University of Manchester Gynaecological Oncology Laboratories, Human Development, St Mary s Hospital, Manchester M13 OJH
    Antivir Ther 11:813-25. 2006
    ....
  16. pmc Biological and hormonal markers of chlamydia, human papillomavirus, and bacterial vaginosis among adolescents attending genitourinary medicine clinics
    L Brabin
    Academic Unit of Obstetrics and Gynaecology and Reproductive Health Care, Research Floor, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, UK
    Sex Transm Infect 81:128-32. 2005
    ..To assess maturity indices, menstrual patterns, hormonal factors, and risk of adolescent genital tract infections...
  17. ncbi request reprint Cervarix--a bivalent L1 virus-like particle vaccine for prevention of human papillomavirus type 16- and 18-associated cervical cancer
    Emma J Crosbie
    University of Manchester, Academic Unit of Obstetrics and Gynaecology, St Mary s Hospital, Whitworth Park, Manchester, M13 0JH, UK
    Expert Opin Biol Ther 7:391-6. 2007
    ..The clinical experience of Cervarix and its potential role in reducing the global burden of cervical cancer is discussed...
  18. doi request reprint Body mass index, hormone replacement therapy, and endometrial cancer risk: a meta-analysis
    Emma J Crosbie
    Gynaecology Oncology Research Group, School of Cancer and enabling Sciences, University of Manchester, Manchester, UK
    Cancer Epidemiol Biomarkers Prev 19:3119-30. 2010
    ..Body mass index (BMI) is a risk factor for endometrial cancer. We quantified the risk and investigated whether the association differed by use of hormone replacement therapy (HRT), menopausal status, and histologic type...
  19. ncbi request reprint The use of vaccines in the prevention and treatment of cervical cancer
    Emma J Davidson
    Immunology Group, Paterson Institute for Cancer Research, Christie Hospital NHS Trust, Manchester, UK
    Clin Oncol (R Coll Radiol) 14:193-200. 2002
    ..A papillomavirus vaccine that prevented HPV infection on the one hand and acted against established disease on the other, would have a profound impact on one of the major cancers affecting women globally...
  20. doi request reprint Therapy of human papillomavirus-related disease
    Peter L Stern
    Paterson Institute for Cancer Research, University of Manchester, Manchester M20 4BX, UK
    Vaccine 30:F71-82. 2012
    ..This article forms part of a special supplement entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012...
  21. ncbi request reprint Future acceptance of adolescent human papillomavirus vaccination: a survey of parental attitudes
    Loretta Brabin
    Academic Unit of Obstetrics and Gynaecology, University of Manchester, Manchester, M13 OJH, UK
    Vaccine 24:3087-94. 2006
    ..It will be important to raise general awareness of the role of HPV in cervical cancer without stigmatizing the vaccine...
  22. ncbi request reprint To stage or not to stage? That is the question: (with apologies to Shakespeare)
    Henry C Kitchener
    University of Manchester, Manchester, UK
    Int J Gynecol Cancer 20:S55-6. 2010
    ..Until new trial evidence is produced to the contrary, routine lymphadenectomy cannot be recommended for endometrial cancer...
  23. ncbi request reprint Adjuvant chemotherapy improves survival after resection of stage 1 ovarian cancer
    Henry C Kitchener
    University of Manchester, Manchester, UK
    Cancer Treat Rev 31:323-7. 2005
  24. pmc Prevalence of type-specific HPV infection by age and grade of cervical cytology: data from the ARTISTIC trial
    A Sargent
    Division of Cancer Studies and Imaging, University of Manchester, Hathersage Road, Manchester M13 0JH, UK
    Br J Cancer 98:1704-9. 2008
    ..In the absence of broader cross-protection, the large majority of low-grade and many high-grade abnormalities may still occur in sexually active vaccinated women...
  25. pmc HPV testing in routine cervical screening: cross sectional data from the ARTISTIC trial
    H C Kitchener
    Division of Human Development, University of Manchester, Hathersage Road, Manchester M13 0JH, UK
    Br J Cancer 95:56-61. 2006
    ..HPV 16 and HPV 18 are more predictive of underlying disease, but other HPV types account for 30% of high-grade disease...
  26. ncbi request reprint Surgery for endometrial cancer: what type and by whom?
    H C Kitchener
    Academic Unit of Obstetrics and Gynaecology, St Mary s Hospital, Manchester, Whitworth Park, M13 0JH, UK
    Best Pract Res Clin Obstet Gynaecol 15:407-15. 2001
    ..However, consideration should be given to pelvic lymphadenectomy in high-risk cases. Surgery for high-risk endometrial cancer should be performed by gynaecological oncologists...
  27. doi request reprint ARTISTIC: a randomised trial of human papillomavirus (HPV) testing in primary cervical screening
    H C Kitchener
    School of Cancer and Imaging Sciences, University of Manchester, St Mary s Hospital, Manchester, UK
    Health Technol Assess 13:1-150, iii-iv. 2009
    ..CIN3+?; Is HPV testing cost-effective in primary cervical screening?; Is its use associated with adverse psychosocial or psychosexual effects?; and How would it perform as an initial screening test followed by cytology for HPV positivity?..
  28. ncbi request reprint Clinical practice guidelines: loss of clinical freedom or a coming of age?
    H C Kitchener
    Academic Unit of Obstetrics and Gynaecology, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, United Kingdom
    Int J Gynecol Cancer 12:332-6. 2002
    ..The articles will be informative, punchy and provocative. The first of these contributions looks at clinical guidelines: what are they for, how do we produce them and is there any evidence that they do any good?..
  29. ncbi request reprint The IL-10 -1082G polymorphism is associated with clearance of HPV infection
    F Farzaneh
    Academic Unit of Obstetrics and Gynaecology, St Mary s Hospital, Manchester, UK
    BJOG 113:961-4. 2006
    ..028 [95% CI 0.001-0.66], P= 0.001). This preliminary study suggests that higher levels of IL-10 may prevent cervical neoplasia through their role in eliminating HPV...
  30. ncbi request reprint The neoadjuvant approach in the treatment of patients with advanced epithelial ovarian carcinoma
    D D Rosa
    Cancer Research UK Department of Medical Oncology, Christie Hospital NHS Trust, Withington, Manchester, UK
    Clin Oncol (R Coll Radiol) 19:125-8. 2007
    ..This work was designed to verify whether the neoadjuvant approach had an effect on survival in patients with advanced-stage ovarian cancer...
  31. ncbi request reprint The psychosocial impact of human papillomavirus testing in primary cervical screening-a study within a randomized trial
    H C Kitchener
    Division of Human Development, Academic Unit of Obstetrics and Gynaecology, University of Manchester, Manchester, United Kingdom
    Int J Gynecol Cancer 18:743-8. 2008
    ..HPV testing does not add significant psychologic distress when combined with cytology in routine primary cervical screening...
  32. doi request reprint HPV testing as an adjunct to cytology in the follow up of women treated for cervical intraepithelial neoplasia
    H C Kitchener
    Academic Unit of Obstetrics and Gynaecology, School of Cancer and Imaging Science, University of Manchester, Manchester, UK
    BJOG 115:1001-7. 2008
    ..To evaluate human papillomavirus (HPV) testing in combination with cytology in the follow up of treated women...
  33. pmc Factors affecting vaginal pH levels among female adolescents attending genitourinary medicine clinics
    L Brabin
    Academic Unit of Obstetrics and Gynaecology and Reproductive Health Care, Research Floor, St Mary s Hospital, Whitworth Park, Manchester M13 0JH, UK
    Sex Transm Infect 81:483-7. 2005
    ..We assessed hormonal factors and risk of abnormal vaginal pH and bacterial vaginosis (BV) among adolescents attending genitourinary medicine (GUM) clinics...
  34. pmc Requirement for expert histopathological assessment of ovarian cancer and borderline tumors
    P S Sengupta
    Department of Medical Oncology, Christie Hospital National Health Trust, Withington, Manchester, UK
    Br J Cancer 82:760-2. 2000
    ..Interestingly, 24 patients (38.1%) reported a family history of epithelial cancer, a finding that has not been reported previously. Campaign..
  35. ncbi request reprint Stage- and CA125-related survival in patients with epithelial ovarian cancer treated at a cancer center
    R E Board
    Cancer Research UK Department of Medical Oncology, Christie Hospital, Manchester, United Kingdom
    Int J Gynecol Cancer 16:18-24. 2006
    ..Further clinical trials are needed to test whether combinations of surgical, histologic, biochemical, and radiologic parameters can be used to identify a population with such a good prognosis that adjuvant therapy is not required...
  36. ncbi request reprint The interval from surgery to chemotherapy in the treatment of advanced epithelial ovarian carcinoma
    D D Rosa
    Cancer Research UK Department of Medical Oncology, Christie Hospital NHS Trust, Withington, Manchester
    Eur J Surg Oncol 32:588-91. 2006
    ..To study the effect of the interval between surgery and the start of chemotherapy in the treatment of patients with advanced ovarian cancer...
  37. ncbi request reprint Age-restricted cervical screening: HPV testing at age 50 identifies a high risk group for cervical disease
    M E Cruickshank
    Wellbeing Center for the Prevention of Cervical Cancer, Aberdeen Maternity Hospital, University of Aberdeen, Aberdeen, UK
    Int J Gynecol Cancer 12:735-40. 2002
    ..These findings suggest that HPV testing could be a valuable means of identifying the small proportion of women still at risk after 50, and of releasing health care resources...
  38. ncbi request reprint Immunological and viral factors associated with the response of vulval intraepithelial neoplasia to photodynamic therapy
    E S Abdel-Hady
    University of Manchester, Academic Department of Obstetrics and Gynaecology and Reproductive Health Care, St. Mary's Hospital, United Kingdom
    Cancer Res 61:192-6. 2001
    ..0001). These data clearly support the contention that high-risk HPV infection and lack of cell-mediated immunity may play a role in the observed poor response of lower genital lesions to topical PDT...
  39. ncbi request reprint Pattern of failure and long-term morbidity in patients undergoing postoperative radiotherapy for cervical cancer
    P Jain
    Department of Clinical Oncology, Christie Hospital, Manchester, United Kingdom
    Int J Gynecol Cancer 16:1839-45. 2006
    ..Multidisciplinary team working, as recommended by national guidelines from 1999, should allow better patient selection for treatment...