Research Topics | Irving KirschSummaryAffiliation: University of Plymouth Country: UK Publications
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Publications
Placebo psychotherapy: synonym or oxymoron?Irving Kirsch
Faculty of Health and Social Work, University of Plymouth, UK
J Clin Psychol 61:791-803. 2005..The idea of evaluating the efficacy of psychotherapy by controlling for nonspecific or placebo factors is based on a flawed analogy and should be abandoned...
Consistency of the placebo effectBen Whalley
School of Psychology, University of Plymouth, Plymouth, UK
J Psychosom Res 64:537-41. 2008..For prediction to be possible, the response to placebo must be reliable. We tested the consistency of the placebo effect by assessing the response to four trials of placebo analgesic treatment...
Components of placebo effect: randomised controlled trial in patients with irritable bowel syndromeTed J Kaptchuk
Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
BMJ 336:999-1003. 2008..To assess the relative magnitude of these components...
Do "placebo responders" exist?Ted J Kaptchuk
Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
Contemp Clin Trials 29:587-95. 2008..Finally, this paper proposes one model to rigorously investigate the stability of placebo responses...
Placebo analgesia: findings from brain imaging studies and emerging hypothesesJian Kong
Department of Psychiatry, Massachusetts General Hospital, Charlestown, MA, USA
Rev Neurosci 18:173-90. 2007..The literature suggests that multiple brain regions, including the anterior cingulate cortex, anterior insula, prefrontal cortex and periaqueductal grey, play a pivotal role in these processes...
Clinical trials and the response rate illusionIrving Kirsch
Psychology, University of Hull, Hull HU6 7RX, United Kingdom
Contemp Clin Trials 28:348-51. 2007..Response rates based on continuous data do not add information, and they can create an illusion of clinical effectiveness...
Investigating placebo effects in irritable bowel syndrome: a novel research designLisa A Conboy
Osher Institute, Division for Research and Education in Complementary and Integrative Therapies, Harvard Medical School, 401 Park Drive, Suite 22A, Boston, MA 02115, USA
Contemp Clin Trials 27:123-34. 2006..quot; The trial also uses an innovative combination of quantitative and qualitative methods...
Brain activity associated with expectancy-enhanced placebo analgesia as measured by functional magnetic resonance imagingJian Kong
Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
J Neurosci 26:381-8. 2006..Our results suggest that placebo analgesia may be configured through multiple brain pathways and mechanisms...
Conditioning, expectancy, and the placebo effect: comment on Stewart-Williams and Podd (2004)Irving Kirsch
Department of Psychology, University of Connecticut, Storrs, CT 06269 1020, USA
Psychol Bull 130:341-3; discussion 344-5. 2004..Thus, the higher up the phylogenetic scale, the smaller the role of nonconscious conditioning processes and the larger the role of cognition...
National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disordersDennis S Charney
Division of Intramural Research Programs, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
Arch Gen Psychiatry 59:262-70. 2002..Research is needed on the ethical conduct of studies to limit risks of medication-free intervals and facilitate poststudy treatment. Patients must fully understand the risks and lack of individualized treatment involved in research...
