Irving Kirsch

Summary

Affiliation: University of Hull
Country: UK

Publications

  1. ncbi request reprint Hypnotic history: a reply to critics
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, HU6 7RX United Kingdom
    Am J Clin Hypn 49:249-54. 2007
  2. doi request reprint Consistency of the placebo effect
    Ben Whalley
    School of Psychology, University of Plymouth, Plymouth, UK
    J Psychosom Res 64:537-41. 2008
  3. ncbi request reprint National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders
    Dennis S Charney
    Division of Intramural Research Programs, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 59:262-70. 2002
  4. ncbi request reprint Antidepressants and the placebo response
    Irving Kirsch
    Department of Psychology, University of Hull, Cottingham Road, Hull, HU6 7RX, United Kingdom
    Epidemiol Psichiatr Soc 18:318-22. 2009
  5. doi request reprint The placebo effect revisited: lessons learned to date
    Irving Kirsch
    Program in Placebo Studies, Harvard Medical School, Boston, USA
    Complement Ther Med 21:102-4. 2013
  6. ncbi request reprint Suggestion in the treatment of depression
    Irving Kirsch
    University of Plymouth, Plymouth, United Kingdom
    Am J Clin Hypn 55:221-9. 2013
  7. ncbi request reprint Clinical trials and the response rate illusion
    Irving Kirsch
    Psychology, University of Hull, Hull HU6 7RX, United Kingdom
    Contemp Clin Trials 28:348-51. 2007
  8. pmc Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, United Kingdom
    PLoS Med 5:e45. 2008
  9. doi request reprint Suggestibility and suggestive modulation of the Stroop effect
    Irving Kirsch
    University of Hull, Hull, HU6 7RX, UK
    Conscious Cogn 20:335-6. 2011
  10. ncbi request reprint Remembrance of hypnosis past
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, HU6 7RX, United Kingdom
    Am J Clin Hypn 49:171-8; discussion 179-80, 183-4. 2007

Detail Information

Publications38

  1. ncbi request reprint Hypnotic history: a reply to critics
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, HU6 7RX United Kingdom
    Am J Clin Hypn 49:249-54. 2007
    ....
  2. doi request reprint Consistency of the placebo effect
    Ben Whalley
    School of Psychology, University of Plymouth, Plymouth, UK
    J Psychosom Res 64:537-41. 2008
    ..For prediction to be possible, the response to placebo must be reliable. We tested the consistency of the placebo effect by assessing the response to four trials of placebo analgesic treatment...
  3. ncbi request reprint National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders
    Dennis S Charney
    Division of Intramural Research Programs, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 59:262-70. 2002
    ..Research is needed on the ethical conduct of studies to limit risks of medication-free intervals and facilitate poststudy treatment. Patients must fully understand the risks and lack of individualized treatment involved in research...
  4. ncbi request reprint Antidepressants and the placebo response
    Irving Kirsch
    Department of Psychology, University of Hull, Cottingham Road, Hull, HU6 7RX, United Kingdom
    Epidemiol Psichiatr Soc 18:318-22. 2009
    ..To evaluate new generation antidepressants in relation to the placebo response...
  5. doi request reprint The placebo effect revisited: lessons learned to date
    Irving Kirsch
    Program in Placebo Studies, Harvard Medical School, Boston, USA
    Complement Ther Med 21:102-4. 2013
    ....
  6. ncbi request reprint Suggestion in the treatment of depression
    Irving Kirsch
    University of Plymouth, Plymouth, United Kingdom
    Am J Clin Hypn 55:221-9. 2013
    ..These data thus indicate that suggestion is a central factor in treating depression. Therefore, the use of hypnosis, which is based on suggestion, as a treatment adjunct can be expected to enhance treatment outcome...
  7. ncbi request reprint Clinical trials and the response rate illusion
    Irving Kirsch
    Psychology, University of Hull, Hull HU6 7RX, United Kingdom
    Contemp Clin Trials 28:348-51. 2007
    ..Response rates based on continuous data do not add information, and they can create an illusion of clinical effectiveness...
  8. pmc Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, United Kingdom
    PLoS Med 5:e45. 2008
    ..The purpose of this analysis is to establish the relation of baseline severity and antidepressant efficacy using a relevant dataset of published and unpublished clinical trials...
  9. doi request reprint Suggestibility and suggestive modulation of the Stroop effect
    Irving Kirsch
    University of Hull, Hull, HU6 7RX, UK
    Conscious Cogn 20:335-6. 2011
    ..Research aimed at uncovering the means by which low suggestible individuals are able to modulate the Stroop effect would be welcome, as would assessment of this effect in moderately suggestible people...
  10. ncbi request reprint Remembrance of hypnosis past
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, HU6 7RX, United Kingdom
    Am J Clin Hypn 49:171-8; discussion 179-80, 183-4. 2007
    ..The importance of these data to both clinical and experimental hypnosis is emphasized...
  11. doi request reprint The altered state issue: dead or alive?
    Irving Kirsch
    Department of Psychology, University of Hull, Hull, HU6 7RX, United Kingdom
    Int J Clin Exp Hypn 59:350-62. 2011
    ..Recent brain imaging data from the University of Hull are reviewed with respect to their implications concerning the existence and functional significance of the hypothesized hypnotic state...
  12. pmc Components of placebo effect: randomised controlled trial in patients with irritable bowel syndrome
    Ted J Kaptchuk
    Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
    BMJ 336:999-1003. 2008
    ..To assess the relative magnitude of these components...
  13. doi request reprint Suggested visual hallucination without hypnosis enhances activity in visual areas of the brain
    William J McGeown
    Department of Psychology, University of Hull, UK
    Conscious Cogn 21:100-16. 2012
    ..The results indicate that a hypnotic induction, although having the potential to enhance the ability of high suggestible people, is not necessary for the effective alteration of color perception by suggestion...
  14. doi request reprint Hypnotic induction decreases anterior default mode activity
    William J McGeown
    Department of Psychology, University of Hull, UK
    Conscious Cogn 18:848-55. 2009
    ..The findings indicate that hypnotic induction creates a distinctive and unique pattern of brain activation in highly suggestible subjects...
  15. doi request reprint Neuroimaging resolution of the altered state hypothesis
    Giuliana Mazzoni
    Department of Psychology, University of Hull, UK
    Cortex 49:400-10. 2013
    ..It also remains uncertain whether the changes in activation produced by hypnotic inductions reflect a uniquely hypnotic state as opposed to more mundane processes...
  16. doi request reprint Suggested visual hallucinations in and out of hypnosis
    Giuliana Mazzoni
    University of Hull, Department of Psychology, Cottingham Road, Hull HU5 3EY, United Kingdom
    Conscious Cogn 18:494-9. 2009
    ....
  17. pmc Active albuterol or placebo, sham acupuncture, or no intervention in asthma
    Michael E Wechsler
    Division of Pulmonary and Critical Care Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 365:119-26. 2011
    ..We compared the effects of a bronchodilator, two placebo interventions, and no intervention on outcomes in patients with asthma...
  18. doi request reprint The effects of observation and gender on psychogenic symptoms
    Giuliana Mazzoni
    Department of Psychology, University of Hull, Cottingham Road, Hull HU6 7RX, England
    Health Psychol 29:181-5. 2010
    ..To assess the effects of modeling and its interaction with gender in the production of psychogenic symptoms...
  19. pmc Placebos without deception: a randomized controlled trial in irritable bowel syndrome
    Ted J Kaptchuk
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 5:e15591. 2010
    ..We tested whether open-label placebo (non-deceptive and non-concealed administration) is superior to a no-treatment control with matched patient-provider interactions in the treatment of irritable bowel syndrome (IBS)...
  20. pmc Sham device v inert pill: randomised controlled trial of two placebo treatments
    Ted J Kaptchuk
    Osher Institute, Harvard Medical School, Boston, MA, 02215 USA
    BMJ 332:391-7. 2006
    ..To investigate whether a sham device (a validated sham acupuncture needle) has a greater placebo effect than an inert pill in patients with persistent arm pain...
  21. pmc A functional magnetic resonance imaging study on the neural mechanisms of hyperalgesic nocebo effect
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Massachusetts General Hospital, Massachusetts Institute of Technology Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Boston, Massachusetts 02215, USA
    J Neurosci 28:13354-62. 2008
    ..In conclusion, we found evidence that nocebo hyperalgesia may be predominantly produced through an affective-cognitive pain pathway (medial pain system), and the left hippocampus may play an important role in this process...
  22. doi request reprint Do "placebo responders" exist?
    Ted J Kaptchuk
    Osher Research Center, Harvard Medical School, 401 Park Drive, Boston, MA 02215, USA
    Contemp Clin Trials 29:587-95. 2008
    ..Finally, this paper proposes one model to rigorously investigate the stability of placebo responses...
  23. ncbi request reprint The effects of hypnotic and nonhypnotic imaginative suggestion on pain
    Leonard S Milling
    University of Hartford, Department of Psychology, West Hartford, CT 06117, USA
    Ann Behav Med 29:116-27. 2005
    ..Few studies have compared placebo and suggested pain reduction...
  24. ncbi request reprint Immediate and persisting effects of misleading questions and hypnosis on memory reports
    Alan Scoboria
    Department of Psychology, University of Connecticut, USA
    J Exp Psychol Appl 8:26-32. 2002
    ..There were no significant interactions with level of hypnotic suggestibility. Implications of these findings for the per se exclusion of posthypnotic testimony are discussed...
  25. doi request reprint Altered placebo and drug labeling changes the outcome of episodic migraine attacks
    Slavenka Kam-Hansen
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Sci Transl Med 6:218ra5. 2014
    ..The benefits of placebo persisted even if placebo was honestly described. Whether treatment involves medication or placebo, the information provided to patients and the ritual of pill taking are important components of care. ..
  26. pmc Default mode network connectivity encodes clinical pain: an arterial spin labeling study
    Marco L Loggia
    Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School HMS, Boston, MA, USA
    Pain 154:24-33. 2013
    ..Our results support the use of arterial spin labeling to evaluate clinical pain, and the use of resting DMN connectivity as a potential neuroimaging biomarker for chronic pain perception...
  27. ncbi request reprint Investigating placebo effects in irritable bowel syndrome: a novel research design
    Lisa A Conboy
    Osher Institute, Division for Research and Education in Complementary and Integrative Therapies, Harvard Medical School, 401 Park Drive, Suite 22A, Boston, MA 02115, USA
    Contemp Clin Trials 27:123-34. 2006
    ..quot; The trial also uses an innovative combination of quantitative and qualitative methods...
  28. ncbi request reprint Conditioning, expectancy, and the placebo effect: comment on Stewart-Williams and Podd (2004)
    Irving Kirsch
    Department of Psychology, University of Connecticut, Storrs, CT 06269 1020, USA
    Psychol Bull 130:341-3; discussion 344-5. 2004
    ..Thus, the higher up the phylogenetic scale, the smaller the role of nonconscious conditioning processes and the larger the role of cognition...
  29. ncbi request reprint Placebo psychotherapy: synonym or oxymoron?
    Irving Kirsch
    Faculty of Health and Social Work, University of Plymouth, UK
    J Clin Psychol 61:791-803. 2005
    ..The idea of evaluating the efficacy of psychotherapy by controlling for nonspecific or placebo factors is based on a flawed analogy and should be abandoned...
  30. pmc Efficacy of antidepressants in adults
    Joanna Moncrieff
    Department of Mental Health Sciences, University College London, London W1N 8AA
    BMJ 331:155-7. 2005
  31. ncbi request reprint Brain activity associated with expectancy-enhanced placebo analgesia as measured by functional magnetic resonance imaging
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Neurosci 26:381-8. 2006
    ..Our results suggest that placebo analgesia may be configured through multiple brain pathways and mechanisms...
  32. ncbi request reprint Suggestion reduces the stroop effect
    Amir Raz
    Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, MRI Unit in the Department of Psychiatry, Division of Child and Adolescent Psychiatry, New York, NY 10032, USA
    Psychol Sci 17:91-5. 2006
    ..These findings indicate that suggestion can at least partially overcome the automaticity associated with the Stroop effect...
  33. ncbi request reprint Effects of misleading questions and hypnotic memory suggestion on memory reports: a signal-detection analysis
    Alan Scoboria
    University of Windsor, Ontario, Canada
    Int J Clin Exp Hypn 54:340-59. 2006
    ..Signal detection analysis indicated that misleading questioning produced decreased sensitivity accompanied by higher response bias, though affecting sensitivity more than producing a criterion shift...
  34. ncbi request reprint Illness by suggestion: expectancy, modeling, and gender in the production of psychosomatic symptoms
    William Lorber
    University of Connecticut, USA
    Ann Behav Med 33:112-6. 2007
    ..Expectancy and modeling have been cited as factors in mass psychogenic illness (MPI), which reportedly affects more women than men...
  35. ncbi request reprint Placebo analgesia: findings from brain imaging studies and emerging hypotheses
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, MA, USA
    Rev Neurosci 18:173-90. 2007
    ..The literature suggests that multiple brain regions, including the anterior cingulate cortex, anterior insula, prefrontal cortex and periaqueductal grey, play a pivotal role in these processes...
  36. doi request reprint The effect of posthypnotic suggestion, hypnotic suggestibility, and goal intentions on adherence to medical instructions
    Claudia Carvalho
    Higher Institute of Applied Psychology, Lisbon, Portugal
    Int J Clin Exp Hypn 56:143-55. 2008
    ..Posthypnotic suggestion enhanced adherence among high suggestible participants but lowered it among low suggestibles...
  37. pmc Moving beyond depression: How full is the glass?
    Irving Kirsch
    BMJ 336:629-30. 2008
  38. ncbi request reprint Antidepressant drugs 'work', but they are not clinically effective
    Irving Kirsch
    Br J Hosp Med (Lond) 69:359. 2008