A J Kirkup
Affiliation: University of Sheffield
- Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised ratA J Kirkup
Department of Biomedical Science, Alfred Denny Building, University of Sheffield, Western Bank, UK
J Physiol 520:551-63. 1999....
- Somatostatin sst(2) receptor-mediated inhibition of mesenteric afferent nerves of the jejunum in the anesthetized ratC E Booth
Department of Biomedical Science, Alfred Denny Building, University of Sheffield, Western Bank, Sheffield, S10 2TN England
Gastroenterology 121:358-69. 2001..CONCLUSIONS: These data suggest that activation of somatostatin sst(2) receptors inhibit populations of mesenteric afferents likely to be involved in nociceptive transmission...
- Influence of the pattern of jejunal distension on mesenteric afferent sensitivity in the anaesthetized ratC E Booth
Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, UK
Neurogastroenterol Motil 20:149-58. 2008..These findings suggest that the nature of the distension stimulus is critical in determining the pattern of response observed from the various subpopulations of afferents supplying the bowel wall...
- Receptors and transmission in the brain-gut axis: potential for novel therapies. I. Receptors on visceral afferentsA J Kirkup
Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom
Am J Physiol Gastrointest Liver Physiol 280:G787-94. 2001..Accordingly, these receptors represent a rational target for drug treatments aimed at attenuating both the inappropriate visceral sensation and the aberrant reflex activity that are the foundation for alterations in bowel function...