Research Topics
| A J KirkupSummaryAffiliation: University of Sheffield Country: UK Publications
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Detail Information
Publications
Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised ratA J Kirkup
Department of Biomedical Science, Alfred Denny Building, University of Sheffield, Western Bank, UK
J Physiol 520:551-63. 1999....
Somatostatin sst(2) receptor-mediated inhibition of mesenteric afferent nerves of the jejunum in the anesthetized ratC E Booth
Department of Biomedical Science, Alfred Denny Building, University of Sheffield, Western Bank, Sheffield, S10 2TN England
Gastroenterology 121:358-69. 2001..CONCLUSIONS: These data suggest that activation of somatostatin sst(2) receptors inhibit populations of mesenteric afferents likely to be involved in nociceptive transmission...
Influence of the pattern of jejunal distension on mesenteric afferent sensitivity in the anaesthetized ratC E Booth
Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield, UK
Neurogastroenterol Motil 20:149-58. 2008..These findings suggest that the nature of the distension stimulus is critical in determining the pattern of response observed from the various subpopulations of afferents supplying the bowel wall...
Receptors and transmission in the brain-gut axis: potential for novel therapies. I. Receptors on visceral afferentsA J Kirkup
Department of Biomedical Science, University of Sheffield, Western Bank, Sheffield S10 2TN, United Kingdom
Am J Physiol Gastrointest Liver Physiol 280:G787-94. 2001..Accordingly, these receptors represent a rational target for drug treatments aimed at attenuating both the inappropriate visceral sensation and the aberrant reflex activity that are the foundation for alterations in bowel function...
