Ann E Kingsbury
Affiliation: University College London
- Brain stem pathology in Parkinson's disease: an evaluation of the Braak staging modelAnn E Kingsbury
Reta Lila Weston Institute of Neurological Studies, UCL, Institute of Neurology, London, United Kingdom
Mov Disord 25:2508-15. 2010..These findings broadly support the Braak hypothesis of caudo-rostral development but indicate that the extent of the disease in the cortex and the severity of pathology in the medulla were independent of one another...
- Synphilin-1 and parkin show overlapping expression patterns in human brain and form aggresomes in response to proteasomal inhibitionRina Bandopadhyay
Reta Lila Weston Institute of Neurological Studies, Royal Free and UCL Medical School, The Windeyer Building, 46 Cleveland Street, London W1T 4JF, UK
Neurobiol Dis 20:401-11. 2005..We confirm that synphilin-1 and parkin are components of majority of LBs in Parkinson's disease and that both proteins are susceptible to proteasomal degradation...
- Development, characterisation and epitope mapping of novel monoclonal antibodies for DJ-1 (PARK7) proteinRina Bandopadhyay
Reta Lila Weston Institute of Neurological Studies, Royal Free and UCL Medical School, The Windeyer Building, 46, Cleveland Street, London W1T 4JF, UK
Neurosci Lett 383:225-30. 2005..These antibodies could be exploited as important tools in dissecting out DJ-1 expression in different species and examination of the role of DJ-1 in Parkinson's disease...
- Alteration in alpha-synuclein mRNA expression in Parkinson's diseaseAnn E Kingsbury
Queen Square Brain Bank for Neurological Disorders, Institute of Neurology, London, United Kingdom
Mov Disord 19:162-70. 2004..These findings are in broad agreement with other studies of the expression of alpha-synuclein mRNA in human brain and suggest that Lewy body formation is unlikely to be the result of overexpression of alpha-synuclein...