Michael B King

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..The data will inform the power calculation and other aspects of carrying out a definitive randomised controlled trial...

..We wanted to develop a measure of perceived racism in UK African-Caribbean patients with psychosis..

..Here we explain the general methodology of the predictD-Spain study and evaluate the reliability of the questionnaires used...

..They also constitute a major resource pressure for mental health services, social services, informal carers and society as a whole...

..Our aim was to survey a representative sample of professional members of the main United Kingdom psychotherapy and psychiatric organisations about their views and practices concerning such treatments...

..The MATISSE study aims to evaluate the clinical and cost effectiveness of group Art Therapy for people with schizophrenia...

..The hypothesis is that structured, pro-active care of patients with chronic depression in primary care will lead to a cost-effective improvement in medical and social outcomes when compared with usual general practitioner (GP) care...

..The main aim of the study is to explore the economic impact of chronic fatigue in patients seeking help from general practitioners and to identify characteristics that explain variations in costs...

..In this study, we present the reliability, construct validity and accuracy of the PHQ-9 and PHQ-2 to detect major depressive disorder in primary care...

..However, we lack reliable and valid methods of risk estimation. This protocol paper introduces PREDICT, an international research study to address this risk estimation...

..The morbidity of gay, lesbian or bisexual people attending family practice has not been previously assessed. We compared health measures of family practice attendees classified as lesbian, gay and bisexual...

..There are, however, a number of alternative explanations for our finding, including unknown psychological and social factors, which might mediate the association between family size and sexual orientation...

..Stimulating though it is, their debate left me wondering about the wider philosophical and ethical implications behind our rush to therapy...

..The authors argue that legal and social recognition of same sex relationships may reduce discrimination, increase the stability of same sex relationships, and lead to better physical and mental health for gay and lesbian people...

..There is evidence that the prevalence of common mental disorders varies across Europe...

..A phase III trial targeting patients with inadequate experienced continuity of care is recommended...

..However, little account is taken of spiritual beliefs that are not tied to personal or public religious practice. Our objective was to develop a standardized measure of spirituality for use in clinical research...

..Strategies for prevention of depression are hindered by lack of evidence about the combined predictive effect of known risk factors...

..However, randomly allocating patients to treatments that do not accord with their preferences may influence internal and external validity...

..Lesbian, gay and bisexual (LGB) people may be at higher risk of mental disorders than heterosexual people...

..All three appear to be important and may explain why published prevalence rates of sexual dysfunction and associated factors are so conflicting...

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..There are no risk models for the prediction of anxiety that may help in prevention. We aimed to develop a risk algorithm for the onset of generalized anxiety and panic syndromes...

..There is concern about the stigma of mental illness, but it is difficult to measure stigma consistently...

..12 (95% CI -0.20, -0.05) to -0.32 (95% CI -0.41, -0.23)). Higher experienced continuity may be linked to lower health care needs in the future...

..This study elicited the views of primary and specialty mental health care staff and service users about such service arrangements and barriers to implementation...

..People with severe mental illness (SMI) appear to have an elevated risk of death from cardiovascular disease, but results regarding cancer mortality are conflicting...

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..We explored the views of people with SMI and health professionals from primary care and community mental health teams (CMHTs) on how best to provide these services...

..However, perceptions of mental illness and diagnoses can be helpful and non-stigmatising for some patients...

..Clinical guidelines recommend regular screening for CVD risk factors. We evaluated a nurse led intervention to improve screening rates across the primary-secondary care interface...

..We aimed to systematically assess studies that compared diabetes, dyslipidaemia, hypertension and metabolic syndrome in people with and without SMI...

..We aimed to quantify adverse CHD knowledge, diet and exercise in a representative primary care sample, and to determine whether socio-economic deprivation explained any findings...

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..There is an urgent need for CHD screening and for relevant interventions for smoking cessation and diabetes, as well as advice on diet and exercise, in patients with SMI...

..33-7.94). In schizophrenia, risk was significantly higher when young but marked risk persisted until age 70. Greatest risk was associated with: increased consultation rates; antidepressant prescriptions and living in less deprived areas...

..There has been little research into the prevalence of mental health problems in lesbian, gay and bisexual (LGB) people in the UK with most work conducted in the USA...

..It is currently unclear whether preferences may differ for those patients with milder symptoms compared to those experiencing more severe distress...

..Little is known about the effectiveness of advance care planning in the United Kingdom, although policy documents recommend that it should be available to all those with life-limiting illness...

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..Despite this, older people are rarely offered psychological interventions, and only 3 randomized controlled trials of individual cognitive behavioral therapy (CBT) in a primary care setting have been published...

..This paper reports on participants' service contact, in-patient service use and adverse events 36 months after randomisation...

..Increasing numbers of people will die with dementia, many in the acute hospital. It is often not perceived to be a life-limiting illness...

..This study was designed to examine the effectiveness and costs associated with treatment by a specialist behavior therapy team...

..However, ACT clients were more satisfied and better engaged with services. To understand these findings better, we investigated the content of care and interventions offered to study participants...

..We investigated for the first time in a national survey whether older people were less likely than younger adults with the same symptom severity to receive treatment for Common Mental Disorders (CMD)...

..This paper describes this evidence and the first UK studies that were carried out to evaluate these newly implemented services...

..To develop an end-of-life attitudes questionnaire for use in a large community-based sample of older people...

..Cancer patients who receive care from specialist palliative care services in the UK are younger than those who do not receive this care. This may be explained by age-related differences in attitudes to end-of-life care...

..To compare outcomes of care from assertive community treatment teams with care by community mental health teams for people with serious mental illnesses...

..To investigate the experiences of professionals who administered and evaluated treatments for homosexuality in Britain since the 1950s...

..To assess the effectiveness of teaching general practitioners skills in brief cognitive behaviour therapy...

..Little is known about the mental health of gay men and lesbians living in Europe...

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..There are no epidemiological data in Europe on associations between sexual molestation in males and psychological disturbance...

..We aimed to identify the key components of institutional care for people with longer term mental health problems and the effectiveness of these components...

..CONCLUSION: The definition of same sex attraction as an illness and the development of treatments to eradicate such attraction have had a negative long term impact on individuals...

..If patients make an advance decision to refuse certain treatments, they should be given the opportunity to change their minds in the future...

..Factors associated with depression are usually identified from cross-sectional studies...

..Addressing potential sexual problems during the course of disease may give patients confidence to discuss such issues as they occur, thus avoiding embarrassment or aggravation of the problems later in their illness...

..The aim of this study was to compare the cost-effectiveness of cognitive behaviour therapy (CBT), a talking control (TC) and treatment as usual (TAU), delivered in a primary care setting, for older people with depression...

..CONCLUSIONS: Depression in Irish-born people living in London is associated with poorly planned migration. However, this effect can be modified by experiences following migration...

..CONCLUSION: The findings lend support to the idea that patients with bulimia nervosa can be treated in general practice and that this approach warrants further investigation...

..Caring for relatives with advanced cancer may cause psychological and physical ill health...

..64 (1.04 to 10.32) points. CONCLUSION: People who profess stronger spiritual beliefs seem to resolve their grief more rapidly and completely after the death of a close person than do people with no spiritual beliefs...

..CONCLUSIONS: Users' advance instruction directives had little observable impact on the outcome of care at 12 months...

..We argue that any proposed extension of clergy involvement in mental health will require further research and thorough deliberation by mental health services and religious organisations...

..This paper examines the causal attributes to depression among Irish migrants in the UK in the context of pre- and post-migration experiences with particular focus on gender and age...

..The paper then examines the implications of the model for informed consent and recruitment procedures. Key issues for future research are also outlined...

..Depression is prevalent, costly and often undertreated...

..Our aim was to validate and describe responses to a questionnaire about attitudes to depression and its treatment in a sample with experience of moderate and severe depressive episodes...

..We compared the prevalence of CMD among representative samples of White, Irish, Black Caribbean, Bangladeshi, Indian and Pakistani individuals living in England using a standardized clinical interview...

..The premise was that inhibition of NHE-1 limits intracellcular Na accumulation and thereby limits Na/Ca-exchanger-mediated calcium overload to reduce infarct size...

..To determine (i) the prevalence and characteristics of harmful alcohol consumption in general practice attendees; (ii) social and psychological associations with harmful drinking and (iii) recognition of harmful drinking by GPs...

..The authors aimed to assess the impact of a brief educational and advice support service on carers of patients with a first episode of psychotic illness...

..However, there are very little epidemiological data available on their mental health. In this study, we aimed to examine the prevalence of psychological problems among refugee and migrant schoolchildren compared to their UK-born peers...

..Cancer and non-cancer patients have similar needs for supportive care. We need further evidence on the value of self-rated prognosis and how to provide palliative and supportive care for all patients who are near death...

..We also need to give greater priority to existential issues in validated schedules that measure needs in clinical work and research...

..There is a dearth of research into the mental health of gay men, lesbians and bisexual men and women in the UK...

..1; P = 0.013) suggesting a dose-dependent relationship. Our results are consistent with previous reports suggesting a small but independent effect by the s/s 5-HTTLPR genotype increasing the risk for depression...

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..To assess the feasibility of overcoming sample size limitations in economic analyses of clinical trials through meta-analysis of data on individual patients from multiple trials...

..It will conclude by cautioning users of commercial reconstruction software to validate it for quantitation before using it for dosimetric purposes...

..This study unravels a novel mechanism mediated by the integrin cytoplasmic domain that differentially regulates cell adhesion to LN and cell proliferation in response to IGF...

..It is, therefore, conceivable that reexpression of beta1C will be sufficient to revert a neoplastic phenotype to a nonproliferative and highly adherent normal phenotype...

..However, there has been a failure to examine the form and parameters of partnerships between faith-based organisations and psychiatry...

..These findings indicate that survivin is required to maintain a critical anti-apoptotic threshold in prostate cancer cells and identify integrin signaling as a crucial survival pathway against death receptor-mediated apoptosis...