Jason S King

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. pmc Phospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis
    Arjan Kortholt
    Department of Molecular Cell Biology, University of Groningen, 9751 NN Haren, The Netherlands
    Mol Biol Cell 18:4772-9. 2007
  2. pmc Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt
    Jaiesoon Cho
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Social Services, P O Box 12233, Research Triangle Park, NC 27709, USA
    Proc Natl Acad Sci U S A 105:5998-6003. 2008
  3. pmc Autophagy across the eukaryotes: is S. cerevisiae the odd one out?
    Jason S King
    Beatson Institute for Cancer Research, Garscube Estate, Bearsden, Glasgow, UK
    Autophagy 8:1159-62. 2012
  4. doi request reprint Mechanical stress meets autophagy: potential implications for physiology and pathology
    Jason S King
    Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK
    Trends Mol Med 18:583-8. 2012
  5. pmc The induction of autophagy by mechanical stress
    Jason S King
    Beatson Institute for Cancer Research, Glasgow, Scotland, UK
    Autophagy 7:1490-9. 2011
  6. doi request reprint Chemotaxis: TorC before you Akt
    Jason S King
    CR UK Beatson Institute for Cancer Research, Switchback Road, Bearsden, Glasgow G61 1BD, UK
    Curr Biol 18:R864-6. 2008
  7. doi request reprint Chemotaxis: finding the way forward with Dictyostelium
    Jason S King
    CRUK Beatson Institute, Bearsden, Glasgow, UK
    Trends Cell Biol 19:523-30. 2009
  8. pmc SCAR/WAVE is activated at mitosis and drives myosin-independent cytokinesis
    Jason S King
    Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK
    J Cell Sci 123:2246-55. 2010
  9. doi request reprint Cyclical action of the WASH complex: FAM21 and capping protein drive WASH recycling, not initial recruitment
    Laura Park
    CR UK Beatson Institute for Cancer Research, Glasgow University, Switchback Road, Glasgow G61 1BD, UK
    Dev Cell 24:169-81. 2013
  10. pmc SCAR knockouts in Dictyostelium: WASP assumes SCAR's position and upstream regulators in pseudopods
    Douwe M Veltman
    Beatson Institute for Cancer Research, Glasgow G61 1BD, Scotland, UK
    J Cell Biol 198:501-8. 2012

Collaborators

Detail Information

Publications12

  1. pmc Phospholipase C regulation of phosphatidylinositol 3,4,5-trisphosphate-mediated chemotaxis
    Arjan Kortholt
    Department of Molecular Cell Biology, University of Groningen, 9751 NN Haren, The Netherlands
    Mol Biol Cell 18:4772-9. 2007
    ..These results indicate that local activation of PLC can control PTEN localization and suggest a novel mechanism to regulate the internal PI(3,4,5)P(3) gradient...
  2. pmc Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt
    Jaiesoon Cho
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Social Services, P O Box 12233, Research Triangle Park, NC 27709, USA
    Proc Natl Acad Sci U S A 105:5998-6003. 2008
    ..4. This phenomenon provides a homeostatic mechanism for elevating 2,3-BPG levels, thereby enhancing oxygen release to tissues. Our data indicate greater biological significance of the Rapoport-Luebering shunt than previously considered...
  3. pmc Autophagy across the eukaryotes: is S. cerevisiae the odd one out?
    Jason S King
    Beatson Institute for Cancer Research, Garscube Estate, Bearsden, Glasgow, UK
    Autophagy 8:1159-62. 2012
    ....
  4. doi request reprint Mechanical stress meets autophagy: potential implications for physiology and pathology
    Jason S King
    Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK
    Trends Mol Med 18:583-8. 2012
    ..The induction of autophagy has wide-ranging effects on cells. In this article, I propose that the autophagic response to mechanical stress is an important factor in a wide range of both physiological and pathological settings...
  5. pmc The induction of autophagy by mechanical stress
    Jason S King
    Beatson Institute for Cancer Research, Glasgow, Scotland, UK
    Autophagy 7:1490-9. 2011
    ..The autophagic response is therefore part of an integrated response to mechanical challenge, allowing cells to cope with a continuously changing physical environment...
  6. doi request reprint Chemotaxis: TorC before you Akt
    Jason S King
    CR UK Beatson Institute for Cancer Research, Switchback Road, Bearsden, Glasgow G61 1BD, UK
    Curr Biol 18:R864-6. 2008
    ..Recent work shows that Dictyostelium PKB/Akt can be spatially regulated independently of phosphatidylinositol (3,4,5)-trisphosphate via phosphorylation by TOR complex 2, placing this complex at the hub of chemotaxis...
  7. doi request reprint Chemotaxis: finding the way forward with Dictyostelium
    Jason S King
    CRUK Beatson Institute, Bearsden, Glasgow, UK
    Trends Cell Biol 19:523-30. 2009
    ..Overall we describe how Dictyostelium has the potential to unlock many fundamental questions in the cell motility field...
  8. pmc SCAR/WAVE is activated at mitosis and drives myosin-independent cytokinesis
    Jason S King
    Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow, G61 1BD, UK
    J Cell Sci 123:2246-55. 2010
    ..EB1-null cells also exhibit decreased adhesion during mitosis. Our data reveal a spindle-directed signalling pathway that regulates SCAR activity, migration and adhesion at mitosis...
  9. doi request reprint Cyclical action of the WASH complex: FAM21 and capping protein drive WASH recycling, not initial recruitment
    Laura Park
    CR UK Beatson Institute for Cancer Research, Glasgow University, Switchback Road, Glasgow G61 1BD, UK
    Dev Cell 24:169-81. 2013
    ..Recycling is driven by FAM21's interaction with capping protein, which couples the WASH complex to dynamic actin on vesicles...
  10. pmc SCAR knockouts in Dictyostelium: WASP assumes SCAR's position and upstream regulators in pseudopods
    Douwe M Veltman
    Beatson Institute for Cancer Research, Glasgow G61 1BD, Scotland, UK
    J Cell Biol 198:501-8. 2012
    ..We conclude that WASP and SCAR can regulate pseudopod actin using similar mechanisms...
  11. pmc WASH is required for lysosomal recycling and efficient autophagic and phagocytic digestion
    Jason S King
    Beatson Institute for Cancer Research, Bearsden, Glasgow G61 1BD, United Kingdom Department of Biochemistry, University of Geneva, CH 1211 Geneva, Switzerland Bernhard Nocht Institute for Tropical Medicine, 20359 Hamburg, Germany
    Mol Biol Cell 24:2714-26. 2013
    ..WASH is therefore required for the maturation of lysosomes to a stage at which hydrolases can be retrieved and reused. ..
  12. doi request reprint The use of streptavidin conjugates as immunoblot loading controls and mitochondrial markers for use with Dictyostelium discoideum
    Andrew J Davidson
    Beatson Institute for Cancer Research, Glasgow, UK
    Biotechniques 55:39-41. 2013
    ....