K Khunti

Summary

Affiliation: University of Leicester
Country: UK

Publications

  1. pmc A cluster randomized controlled trial of the effectiveness and cost-effectiveness of intermediate care clinics for diabetes (ICCD): study protocol for a randomized controlled trial
    Natalie Armstrong
    Warwick Medical School, University of Warwick, Coventry, UK
    Trials 13:164. 2012
  2. pmc Let's prevent diabetes: study protocol for a cluster randomised controlled trial of an educational intervention in a multi-ethnic UK population with screen detected impaired glucose regulation
    Laura J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Cardiovasc Diabetol 11:56. 2012
  3. pmc Comparison of efficacy between incretin-based therapies for type 2 diabetes mellitus
    Kaustubh Nisal
    Department of Diabetes and Endocrinology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Infirmary Square, Leicester LE1 5WW, UK
    BMC Med 10:152. 2012
  4. pmc Walking away from type 2 diabetes: trial protocol of a cluster randomised controlled trial evaluating a structured education programme in those at high risk of developing type 2 diabetes
    Thomas Yates
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    BMC Fam Pract 13:46. 2012
  5. pmc Quality of care of people with type 2 diabetes in eight European countries: findings from the Guideline Adherence to Enhance Care (GUIDANCE) study
    Margaret A Stone
    University of Leicester, Leicester, United Kingdom
    Diabetes Care 36:2628-38. 2013
  6. doi request reprint Self-titration of insulin in the management of people with type 2 diabetes: a practical solution to improve management in primary care
    K Khunti
    Diabetes Research Unit, University of Leicester, Leicester, UK
    Diabetes Obes Metab 15:690-700. 2013
  7. pmc Joint prevalence of diabetes, impaired glucose regulation, cardiovascular disease risk and chronic kidney disease in South Asians and White Europeans
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester Diabetes Centre, Leicester General Hospital, Leicester, Leicestershire, United Kingdom
    PLoS ONE 8:e55580. 2013
  8. doi request reprint A comparison of cost per case detected of screening strategies for Type 2 diabetes and impaired glucose regulation: modelling study
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, UK
    Diabetes Res Clin Pract 97:505-13. 2012
  9. pmc Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? The DESMOND SMBG randomised controlled trial protocol
    Helen M Dallosso
    Diabetes Research Department, University Hospitals of Leicester NHS Trust, Leicester, UK
    BMC Fam Pract 13:18. 2012
  10. doi request reprint Validity of self-assessed waist circumference in a multi-ethnic UK population
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 29:404-9. 2012

Collaborators

Detail Information

Publications116 found, 100 shown here

  1. pmc A cluster randomized controlled trial of the effectiveness and cost-effectiveness of intermediate care clinics for diabetes (ICCD): study protocol for a randomized controlled trial
    Natalie Armstrong
    Warwick Medical School, University of Warwick, Coventry, UK
    Trials 13:164. 2012
    ....
  2. pmc Let's prevent diabetes: study protocol for a cluster randomised controlled trial of an educational intervention in a multi-ethnic UK population with screen detected impaired glucose regulation
    Laura J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Cardiovasc Diabetol 11:56. 2012
    ....
  3. pmc Comparison of efficacy between incretin-based therapies for type 2 diabetes mellitus
    Kaustubh Nisal
    Department of Diabetes and Endocrinology, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Infirmary Square, Leicester LE1 5WW, UK
    BMC Med 10:152. 2012
    ..This review is aimed to look at important mechanistic differences between incretin mimetics and enhancers through direct comparison trials and impact of these differences on biochemical, metabolic and patient satisfaction parameters...
  4. pmc Walking away from type 2 diabetes: trial protocol of a cluster randomised controlled trial evaluating a structured education programme in those at high risk of developing type 2 diabetes
    Thomas Yates
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    BMC Fam Pract 13:46. 2012
    ....
  5. pmc Quality of care of people with type 2 diabetes in eight European countries: findings from the Guideline Adherence to Enhance Care (GUIDANCE) study
    Margaret A Stone
    University of Leicester, Leicester, United Kingdom
    Diabetes Care 36:2628-38. 2013
    ..We sought to determine levels of adherence in eight European countries to recommendations for the management of type 2 diabetes and to investigate factors associated with key intermediate outcomes...
  6. doi request reprint Self-titration of insulin in the management of people with type 2 diabetes: a practical solution to improve management in primary care
    K Khunti
    Diabetes Research Unit, University of Leicester, Leicester, UK
    Diabetes Obes Metab 15:690-700. 2013
    ....
  7. pmc Joint prevalence of diabetes, impaired glucose regulation, cardiovascular disease risk and chronic kidney disease in South Asians and White Europeans
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester Diabetes Centre, Leicester General Hospital, Leicester, Leicestershire, United Kingdom
    PLoS ONE 8:e55580. 2013
    ..We estimated the joint prevalence of diabetes, impaired glucose regulation (IGR), high cardiovascular disease (CVD) risk and chronic kidney disease (CKD) among White Europeans and South Asians who would be eligible for the Programme...
  8. doi request reprint A comparison of cost per case detected of screening strategies for Type 2 diabetes and impaired glucose regulation: modelling study
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, UK
    Diabetes Res Clin Pract 97:505-13. 2012
    ..To determine a cost per case detected for different screening strategies for both Type 2 diabetes alone and in combination with impaired glucose regulation...
  9. pmc Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? The DESMOND SMBG randomised controlled trial protocol
    Helen M Dallosso
    Diabetes Research Department, University Hospitals of Leicester NHS Trust, Leicester, UK
    BMC Fam Pract 13:18. 2012
    ..However, what was unclear was whether a cheaper method of self-monitoring (such as urine glucose monitoring) could produce comparable benefit and patient acceptability for less cost...
  10. doi request reprint Validity of self-assessed waist circumference in a multi-ethnic UK population
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 29:404-9. 2012
    ..To investigate validity of waist circumference measurements obtained by self-report and self-measurement with non-verbal pictorial instructions among a multi-ethnic population...
  11. pmc Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester LE1 6TP, UK
    BMJ 344:e2333. 2012
    ..To measure whether the benefits of a single education and self management structured programme for people with newly diagnosed type 2 diabetes mellitus are sustained at three years...
  12. pmc The Reversal Intervention for Metabolic Syndrome (TRIMS) study: rationale, design, and baseline data
    Alison J Dunkley
    Department of Health Sciences, University of Leicester, Leicester, UK
    Trials 12:107. 2011
    ..This paper describes the rationale and design of the TRIMS study, including intervention development, and presents baseline data...
  13. pmc Rationale and study design for a randomised controlled trial to reduce sedentary time in adults at risk of type 2 diabetes mellitus: project stand (Sedentary Time ANd diabetes)
    Emma G Wilmot
    Diabetes Research, Department of Cardiovascular Sciences, University of Leicester, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    BMC Public Health 11:908. 2011
    ..Project STAND (Sedentary Time ANd Diabetes) is a study which aims to reduce sedentary behaviour in younger adults at high risk of T2DM...
  14. doi request reprint Effect of insulin glargine on glycaemic control and weight in obese and non-obese people with type 2 diabetes: data from the AT.LANTUS trial
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 12:683-8. 2010
    ..To explore glucose lowering response to insulin initiation or switch to insulin glargine in obese and non-obese individuals with type 2 diabetes mellitus (T2DM) and to examine weight gain and hypoglycaemic episodes in this group...
  15. ncbi request reprint Physical activity and sedentary behaviours of South Asian and white European children in inner city secondary schools in the UK
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Fam Pract 24:237-44. 2007
    ..Risk factors for cardiovascular disease in children often persist into adulthood. Low levels of physical activity are likely to be linked to the rise in obesity...
  16. ncbi request reprint Quality of diabetes care in the UK: comparison of published quality-of-care reports with results of the Quality and Outcomes Framework for Diabetes
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 24:1436-41. 2007
    ....
  17. ncbi request reprint Primary prevention of type-2 diabetes and heart disease: action research in secondary schools serving an ethnically diverse UK population
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    J Public Health (Oxf) 30:30-7. 2008
    ..We aimed to identify barriers to healthy lifestyles and evaluate the effectiveness of an action research approach to lifestyle modification in secondary schools...
  18. doi request reprint Educational interventions for migrant South Asians with Type 2 diabetes: a systematic review
    K Khunti
    Department of Health Scienes, University of Leicester, University Hospital of Leicester NHS Trust, Leicester, UK
    Diabet Med 25:985-92. 2008
    ..To conduct a systematic review to determine the scope of published assessments of educational initiatives for South Asians with Type 2 diabetes living in Western countries and to consider the effectiveness of reported interventions...
  19. doi request reprint Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with Type 2 diabetes: baseline data from the DESMOND randomized controlled trial
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 25:1454-61. 2008
    ..To describe the characteristics of newly diagnosed people with Type 2 diabetes (T2DM) and compare these with published studies...
  20. ncbi request reprint Accuracy of a 12-lead electrocardiogram in screening patients with suspected heart failure for open access echocardiography: a systematic review and meta-analysis
    K Khunti
    Department of Health Sciences, Division of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Leicester, UK
    Eur J Heart Fail 6:571-6. 2004
    ..Primary outcome measures were sensitivity and specificity, meta-analysed simultaneously to produce a Summary Receiver Operating Characteristic (SROC) curve...
  21. doi request reprint Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: a population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester LE1 6TP, UK
    Prim Care Diabetes 4:25-32. 2010
    ..To estimate the prevalence of metabolic syndrome in a general population sample of south Asians and white Europeans and compare predictors of metabolic syndrome, using ethnic specific definitions of obesity...
  22. doi request reprint Glycaemic goals in patients with type 2 diabetes: current status, challenges and recent advances
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 12:474-84. 2010
    ..These new classes of therapy and other strategies outlined above could help clinicians to individualize treatment and help a greater proportion of patients to achieve long-term control of blood glucose...
  23. pmc Disease management programme for secondary prevention of coronary heart disease and heart failure in primary care: a cluster randomised controlled trial
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, UK
    Heart 93:1398-405. 2007
    ..To evaluate the effect of a disease management programme for patients with coronary heart disease (CHD) and chronic heart failure (CHF) in primary care...
  24. pmc Referral for autopsies: analysis of 651 consecutive deaths in one general practice
    K Khunti
    Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, Leicester, UK
    Postgrad Med J 76:415-6. 2000
    ..Better education and communication between general practitioners, hospital clinicians, pathologists, and coroners may increase the rate of autopsies...
  25. ncbi request reprint Effect of systematic review of medication by general practitioner on drug consumption among nursing-home residents
    K Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, UK
    Age Ageing 29:451-3. 2000
    ..nursing-home patients usually have many medical problems and often take many drugs. They are therefore at risk from drug side effects and interactions...
  26. pmc Who looks after people with diabetes: primary or secondary care?
    K Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, UK
    J R Soc Med 93:183-6. 2000
    ..This survey revealed large variations in delivery of general-practice diabetes care that need to be addressed by better organization and funding...
  27. ncbi request reprint Coronary heart disease in people of south-Asian origin
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester LE5 4PW, UK
    Lancet 364:2077-8. 2004
  28. pmc Collation and comparison of multi-practice audit data: prevalence and treatment of known diabetes mellitus
    K Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital
    Br J Gen Pract 49:375-9. 1999
    ..Despite the large number of studies, previous estimations of prevalence and treatment have been carried out on relatively small numbers of patients, and then in only a few practices in single geographical regions...
  29. ncbi request reprint Systematic review of open access echocardiography for primary care
    Kamlesh Khunti
    Department of Health Sciences, Division of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Eur J Heart Fail 6:79-83. 2004
    ..Suspected heart failure comprises the majority of primary care referrals for open access echocardiography. There is lack of rigorously controlled studies to support widespread establishment of open access echocardiography services...
  30. pmc Diagnosis of patients with chronic heart failure in primary care: usefulness of history, examination, and investigations
    K Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital
    Br J Gen Pract 50:50-4. 2000
    ..These should include an electrocardiogram and, ideally, an echocardiogram. Further research is also needed on the usefulness of signs and symptoms in primary care, as most studies of heart failure have been conducted in secondary care...
  31. pmc Randomised controlled trial of near-patient testing for glycated haemoglobin in people with type 2 diabetes mellitus
    Kamlesh Khunti
    Division of General Practice and Primary Health Care, Department of Health Sciences, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW
    Br J Gen Pract 56:511-7. 2006
    ..Tight glycaemic control in people with type 2 diabetes can lead to a reduction in microvascular and possibly macrovascular complications. The use of near-patient (rapid) testing offers a potential method to improve glycaemic control...
  32. pmc Features of primary care associated with variations in process and outcome of care of people with diabetes
    K Khunti
    Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, Leicester
    Br J Gen Pract 51:356-60. 2001
    ..However, these studies have been conducted in single geographical areas and involved only small numbers of practices...
  33. ncbi request reprint Heart failure in primary care: qualitative study of current management and perceived obstacles to evidence-based diagnosis and management by general practitioners
    Kamlesh Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Eur J Heart Fail 4:771-7. 2002
    ..Despite the evidence that appropriate treatment with angiotensin-converting enzyme inhibitors can improve morbidity, primary care studies show that patients with heart failure are incorrectly diagnosed and inadequately treated...
  34. ncbi request reprint Approaches to the organization of multi-practice audits in primary health care in the UK
    K Khunti
    Eli Lilly National Clinical Audit Centre, Department of General Practice and Primary Health Care, University of Leicester, UK
    Int J Qual Health Care 11:221-6. 1999
    ..To investigate the approaches taken by audit groups in primary care in organizing multi-practice audits and to identify the strengths and weaknesses of the methods used...
  35. doi request reprint Associations of objectively measured sedentary behaviour and physical activity with markers of cardiometabolic health
    J Henson
    Department of Cardiovascular Sciences, University of Leicester, Leicester Diabetes Centre, Leicester General Hospital, Leicester LE5 4PW, UK
    Diabetologia 56:1012-20. 2013
    ....
  36. doi request reprint Prevalence of diabetes and impaired glucose metabolism in younger 'at risk' UK adults: insights from the STAND programme of research
    E G Wilmot
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabet Med 30:671-5. 2013
    ..The aim of this study was to determine the prevalence of impaired glucose metabolism in higher risk younger adults...
  37. doi request reprint Intensive multifactorial intervention improves modelled coronary heart disease risk in screen-detected Type 2 diabetes mellitus: a cluster randomized controlled trial
    D R Webb
    Department of Cardiovascular Sciences, Leicester Royal Infirmary, University of Leicester, Leicester, UK
    Diabet Med 29:531-40. 2012
    ..To compare the effects of intensive multifactorial cardiovascular risk intervention with standard care in screen-detected Type 2 diabetes...
  38. doi request reprint The association between body mass index and health-related quality of life: influence of ethnicity on this relationship
    C McDonough
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 15:342-8. 2013
    ..The influence of ethnicity on this relationship has less frequently been considered. We aimed to explore the relationship between body mass index (BMI) and HRQL in a mixed population of White European (WE) and South Asian (SA) ethnicity...
  39. doi request reprint Implementation of the automated Leicester Practice Risk Score in two diabetes prevention trials provides a high yield of people with abnormal glucose tolerance
    L J Gray
    Department of Health Sciences, University of Leicester, Leicester Diabetes Centre Broadleaf, Leicester General Hospital, Gwendolen Road, Leicester, UK
    Diabetologia 55:3238-44. 2012
    ..The aim of this study was to determine the yield from the LPRS when applied in two diabetes prevention trials...
  40. doi request reprint Levels of physical activity and relationship with markers of diabetes and cardiovascular disease risk in 5474 white European and South Asian adults screened for type 2 diabetes
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, LE3 9QP, UK
    Prev Med 51:290-4. 2010
    ..Investigate levels of physical activity and their association with health in a white European (WE) and South Asian (SA) population...
  41. pmc Rationale and design of the ADDITION-Leicester study, a systematic screening programme and randomised controlled trial of multi-factorial cardiovascular risk intervention in people with type 2 diabetes mellitus detected by screening
    D R Webb
    Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, UK
    Trials 11:16. 2010
    ..Here we describe the rationale and methods of a systematic community screening programme and randomised controlled trial of cardiovascular risk management within a UK multiethnic setting (ADDITION-Leicester)...
  42. doi request reprint Insulin initiation and management in people with Type 2 diabetes in an ethnically diverse population: the healthcare provider perspective
    N Patel
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 29:1311-6. 2012
    ..To explore barriers to prescribing of insulin, particularly delays in initiation, from the perspective of healthcare professionals involved in managing Type 2 diabetes in a multi-ethnic setting...
  43. doi request reprint Detection of impaired glucose regulation and/or type 2 diabetes mellitus, using primary care electronic data, in a multiethnic UK community setting
    L J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetologia 55:959-66. 2012
    ..The aim of this study was to develop and validate a score for detecting the glycaemic categories of impaired glucose regulation (IGR) and type 2 diabetes using the WHO 2011 diagnostic criteria...
  44. doi request reprint Association of cardiac and non-cardiac chronic disease comorbidity on glycaemic control in a multi-ethnic population with type 1 and type 2 diabetes
    R L Mehta
    Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    Postgrad Med J 87:763-8. 2011
    ....
  45. ncbi request reprint Near patient testing for glycated haemoglobin in people with Type 2 diabetes mellitus managed in primary care: acceptability and satisfaction
    M A Stone
    Department of Health Sciences, University of Leicester, Leicester General Hospital, Leicester, UK
    Diabet Med 24:792-5. 2007
    ..To assess the acceptability of and satisfaction with near patient testing for glycated haemoglobin in primary care in patients and health professionals...
  46. doi request reprint The association between anxiety and measures of glycaemia in a population-based diabetes screening programme
    N Aujla
    Department of Health Sciences Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabet Med 28:785-8. 2011
    ..To investigate associations between anxiety and measures of glycaemia in a White European and South Asian population attending community-based diabetes screening...
  47. doi request reprint The Leicester Risk Assessment score for detecting undiagnosed Type 2 diabetes and impaired glucose regulation for use in a multiethnic UK setting
    L J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 27:887-95. 2010
    ..To date no risk assessment scores that can be completed by a lay person have been developed and validated specifically for multiethnic populations in the UK...
  48. ncbi request reprint Features of primary health care teams associated with successful quality improvement of diabetes care: a qualitative study
    K Stevenson
    Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, Leicester, UK
    Fam Pract 18:21-6. 2001
    ..Experimental studies are required to determine whether the development of teamwork enables practice teams to identify and overcome systematically the obstacles to improved quality of patient care that face them...
  49. doi request reprint The Pre-diabetes Risk Education and Physical Activity Recommendation and Encouragement (PREPARE) programme study: are improvements in glucose regulation sustained at 2 years?
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabet Med 28:1268-71. 2011
    ..To determine whether improvements in glucose regulation following the PREPARE structured education programme were sustained at 24 months...
  50. doi request reprint Diagnostic performance of using one- or two-HbA1c cut-point strategies to detect undiagnosed type 2 diabetes and impaired glucose regulation within a multi-ethnic population
    S A Mostafa
    Division of Diabetes and Endocrinology, Department of Cardiovascular Sciences, Level 0, Victoria Building, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
    Diab Vasc Dis Res 10:84-92. 2013
    ..5% (48 mmol/mol) or (b) two HbA1c thresholds where the first cut-point 'rules out' and the second 'rules in' diabetes. HbA1c values in between the thresholds require confirmatory glucose testing for diagnosis...
  51. doi request reprint The effect of increased ambulatory activity on markers of chronic low-grade inflammation: evidence from the PREPARE programme randomized controlled trial
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, UK School of Sport and Exercise Sciences, Loughborough University, UK
    Diabet Med 27:1256-63. 2010
    ..To investigate whether an exercise intervention programme, with or without pedometer use, is effective at reducing chronic low-grade inflammation in those with impaired glucose tolerance...
  52. doi request reprint Effectiveness of interventions for reducing diabetes and cardiovascular disease risk in people with metabolic syndrome: systematic review and mixed treatment comparison meta-analysis
    A J Dunkley
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 14:616-25. 2012
    ..To review the evidence on interventions for reversing metabolic syndrome or preventing development of type 2 diabetes and cardiovascular disease in people with metabolic syndrome...
  53. doi request reprint Fruit and vegetable intake and the association with glucose parameters: a cross-sectional analysis of the Let's Prevent Diabetes Study
    P Carter
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Eur J Clin Nutr 67:12-7. 2013
    ..Fruit and vegetables may confer benefit via their antioxidant capacity, thus we also measured urinary F₂-isoprostanes as a marker for oxidative stress...
  54. pmc Investigating endothelial activation and oxidative stress in relation to glycaemic control in a multiethnic population
    E M Brady
    Department of Diabetes Research, University Hospitals of Leicester, NHS Trust, Leicester LE5 4PW, UK
    Exp Diabetes Res 2012:386041. 2012
    ..An exploration of ethnic differences in measures of oxidative stress and endothelial activation in relation to known cardiovascular risk factors within South Asians (SA) and White Europeans (WE) residing in the UK...
  55. doi request reprint A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity
    L J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Obes Rev 13:483-98. 2012
    ..Those interventions which have now been withdrawn from use (sibutramine and rimonabant) seem to be the most effective, implying that there may be a place in clinical practice for similar drugs if side effects could be avoided...
  56. doi request reprint Preventing type 2 diabetes: can we make the evidence work?
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, UK
    Postgrad Med J 85:475-80. 2009
    ..This article highlights findings from diabetes prevention programmes and discusses key issues involved in translating research into practice...
  57. doi request reprint Evaluation and comparison of guidelines for the management of people with type 2 diabetes from eight European countries
    M A Stone
    University of Leicester, United Kingdom
    Diabetes Res Clin Pract 87:252-60. 2010
    ..Details of recommendations for key process and outcome indicators were also extracted. Appraisal and data extraction were conducted independently by two researchers...
  58. doi request reprint A simple strategy for screening for glucose intolerance, using glycated haemoglobin, in individuals admitted with acute coronary syndrome
    N Gholap
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 29:838-43. 2012
    ....
  59. doi request reprint Contrasting cardiovascular risk profiles and prescribed cardio-protective therapies in newly-diagnosed type 2 diabetes identified through screening and standard practice
    D R Webb
    Department of Cardiovascular Sciences, University of Leicester, UK
    Diabetes Res Clin Pract 91:280-5. 2011
    ..The cardiovascular risk profile of screen-detected (SD) T2DM is ill defined and has not been compared to conventional newly diagnosed (CD) cases...
  60. ncbi request reprint Inequalities in provision of systematic care for patients with diabetes
    K Khunti
    Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, Leicester, UK
    Fam Pract 18:27-32. 2001
    ..The results of this survey will be valuable to primary care groups and organizations responsible for commissioning diabetes services...
  61. doi request reprint The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: a comparison of two screening tools
    N Aujla
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 27:896-905. 2010
    ..An additional aim was to further explore associations of depressive symptoms with impaired glucose regulation (IGR) and Type 2 diabetes mellitus (Type2 DM)...
  62. doi request reprint Impact of metabolic indices on central artery stiffness: independent association of insulin resistance and glucose with aortic pulse wave velocity
    D R Webb
    Diabetes and Vascular Research Group, Department of Cardiovascular Sciences, University of Leicester, Leicester LE1 5WW, UK
    Diabetologia 53:1190-8. 2010
    ..We used carotid-femoral pulse wave velocity ((cf)PWV) to quantify independent associations of fasting glucose, post-challenge glucose and derived insulin resistance (HOMA-IR) with aortic stiffness...
  63. doi request reprint The potential impact of using glycated haemoglobin as the preferred diagnostic tool for detecting Type 2 diabetes mellitus
    S A Mostafa
    Division of Diabetes and Endocrinology, Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, UK
    Diabet Med 27:762-9. 2010
    ..The aim of this study was to examine the potential impact of the preferred use of HbA(1c) as a diagnostic tool on the prevalence and phenotype of T2DM...
  64. ncbi request reprint Insulin glargine and its role in glycaemic management of Type 2 diabetes
    M A Elrishi
    University Hospitals of Leicester NHS Trust, Department of Diabetes and Endocrinology, Level 1, Victoria Building, Leicester Royal Infirmary, Infirmary Square, Leicester, LE1 5WW, UK
    Expert Opin Drug Metab Toxicol 4:1099-110. 2008
    ..Insulin glargine (Lantus) was the first recombinant-DNA long-acting insulin analogue to be licensed for use in the treatment of diabetes mellitus...
  65. doi request reprint Impact of comorbid diabetes on quality of life and perception of angina pain in people with angina registered with general practitioners in the UK
    M A Stone
    Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester LE1 6TP, UK
    Qual Life Res 17:887-94. 2008
    ..To investigate the impact of comorbid diabetes on general and angina-related quality of life (QoL) in people with angina...
  66. doi request reprint Progression rates from HbA1c 6.0-6.4% and other prediabetes definitions to type 2 diabetes: a meta-analysis
    D H Morris
    Diabetes Research Unit, Leicester Diabetes Centre, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester, LE5 4PW, UK
    Diabetologia 56:1489-93. 2013
    ..0-6.4% (42-46 mmol/mol). Comparing progression rates between groups might aid this issue, thus we aimed to accurately estimate progression rates to diabetes from different prediabetes categories...
  67. doi request reprint Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis
    E G Wilmot
    Department of Cardiovascular Sciences, University of Leicester, Leicester Diabetes Centre, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Diabetologia 55:2895-905. 2012
    ..We conducted a systematic review and meta-analysis to examine the association of sedentary time with diabetes, cardiovascular disease and cardiovascular and all-cause mortality...
  68. ncbi request reprint Initiation of insulin glargine in suboptimally controlled patients with type 2 diabetes: sub-analysis of the AT.LANTUS trial comparing treatment outcomes in subjects from primary and secondary care in the UK
    M Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 9:706-13. 2007
    ....
  69. doi request reprint Real-world factors affecting adherence to insulin therapy in patients with Type 1 or Type 2 diabetes mellitus: a systematic review
    M J Davies
    Department of Cardiovascular Sciences, University of Leicester, UK
    Diabet Med 30:512-24. 2013
    ..To identify real-world factors affecting adherence to insulin therapy in patients with Type 1 or Type 2 diabetes mellitus...
  70. doi request reprint Study of Once Daily Levemir (SOLVE™): insights into the timing of insulin initiation in people with poorly controlled type 2 diabetes in routine clinical practice
    K Khunti
    Department of Health Sciences, University of Leicester, 4301 Connecticut Ave NW, Washington, DC 20008, USA
    Diabetes Obes Metab 14:654-61. 2012
    ..The aim of this analysis is to determine the timing of insulin initiation in routine clinical practice, especially in relation to glycaemic control and use of oral antidiabetic drugs (OADs)...
  71. ncbi request reprint Patient safety systems in the primary health care of diabetes—a story of missed opportunities?
    N Taub
    National Institute of Health Research Collaboration for Leadership in Applied Research and Care for Leicestershire, Northamptonshire and Rutland, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    Diabet Med 27:1322-6. 2010
    ..The aims of this study were to review the current state of research into patient safety systems for people with diabetes in primary care...
  72. doi request reprint The DESMOND educational intervention
    M J Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Chronic Illn 4:38-40. 2008
  73. doi request reprint Insulin management in overweight or obese type 2 diabetes patients: the role of insulin glargine
    M Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 10:42-9. 2008
    ..Retrospective subanalyses of earlier trials and ongoing studies would shed further light on the impact of insulin therapy in obese people with T2DM in addition to determination of optimal therapeutic strategies...
  74. doi request reprint The role of physical activity in the management of type 2 diabetes mellitus
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Postgrad Med J 85:129-33. 2009
    ..This review provides an overview of the evidence surrounding the relative importance of physical activity and weight loss in the management of T2DM and highlights key ways of initiating physical activity behaviour change...
  75. pmc The role of physical activity in the management of impaired glucose tolerance: a systematic review
    T Yates
    School of Sports and Exercise Sciences, Loughborough University, Ashby Road, Loughborough, Leicestershire, UK
    Diabetologia 50:1116-26. 2007
    ..These results indicate that the contribution of physical activity independent of dietary or weight loss changes to the prevention of type 2 diabetes in people with prediabetes is equivocal...
  76. doi request reprint Quality of secondary prevention measures in TIA patients: a retrospective cohort study
    K E Lager
    Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester LE1 6TP, UK
    Postgrad Med J 88:305-11. 2012
    ..This study aimed to investigate the quality of secondary stroke prevention in primary care following diagnosis of TIA in a specialist clinic...
  77. doi request reprint An update on exenatide, a novel therapeutic option for patients with type 2 diabetes
    W Crasto
    University Hospitals of Leicester, Leicester, UK
    Drugs Today (Barc) 47:839-56. 2011
    ..Meanwhile, the results from long-term studies to assess cardiovascular benefits with exenatide therapy are eagerly awaited...
  78. doi request reprint Recent advances in the management of type 2 diabetes mellitus: a review
    B T Srinivasan
    Department of Diabetes Research, University Hospitals of Leicester NHS Trust, Leicester, UK
    Postgrad Med J 84:524-31. 2008
    ..This review also includes new agents in the area of weight loss that may have a positive effect for glucose management-for example, rimonabant...
  79. doi request reprint Searching for the right outcome? A systematic review and meta-analysis of controlled trials using carotid intima-media thickness or pulse wave velocity to infer antiatherogenic properties of thiazolidinediones
    D R Webb
    Department of Cardiovascular Sciences, Victoria Building, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    Diabetes Obes Metab 12:124-32. 2010
    ..The aim was to provide an evidence-based overview of TZD intervention studies using markers prospectively linked to vascular outcome in type 2 diabetes...
  80. pmc A cross sectional survey of secondary prevention measures in patients with peripheral arterial disease in primary care
    Alison Dunkley
    Division of General Practice and Primary Health Care, Department of Health Sciences, University of Leicester, Leicester General Hospital, Leicester, UK
    Postgrad Med J 83:602-5. 2007
    ..The National Service Framework for coronary heart disease (CHD) defines standards for the secondary prevention of cardiovascular disease in at risk individuals, including those with peripheral arterial disease (PAD)...
  81. doi request reprint Waist circumference measurement: knowledge, attitudes and barriers in patients and practitioners in a multi-ethnic population
    Alison J Dunkley
    Department of Health Sciences, University of Leicester and University Hospitals of Leicester NHS Trust, UK
    Fam Pract 26:365-71. 2009
    ..The primary health care team are ideally suited to screen for people at high risk of glucose intolerance and increased cardiovascular risk using waist circumference measurement (WCM)...
  82. pmc Effectiveness of a pragmatic education program designed to promote walking activity in individuals with impaired glucose tolerance: a randomized controlled trial
    Thomas Yates
    Department of Cardiovascular Sciences, University of Leicester, U K
    Diabetes Care 32:1404-10. 2009
    ..This result is likely to have important implications for future primary care-based diabetes prevention initiatives...
  83. pmc The prevalence of depression in white-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus
    Navneet Aujla
    Department of Health Sciences, University of Leicester, Leicester, United Kingdom
    PLoS ONE 4:e7755. 2009
    ....
  84. doi request reprint Is having a family history of type 2 diabetes or cardiovascular disease a predictive factor for metabolic syndrome?
    Alison J Dunkley
    Department of Health Sciences, University of Leicester, Leicester, United Kingdom
    Prim Care Diabetes 3:49-56. 2009
    ..Also, to establish if the association is different for South Asians compared to White Europeans, and for obese compared to non-obese individuals...
  85. ncbi request reprint Community screening for left ventricular systolic dysfunction using plasma and urinary natriuretic peptides
    Leong L Ng
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, United Kingdom
    J Am Coll Cardiol 45:1043-50. 2005
    ..We sought to compare urinary and plasma N-terminal pro-brain natriuretic peptide (N-BNP) in left ventricular systolic dysfunction (LVSD) diagnosis...
  86. pmc Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis
    Patrice Carter
    Diabetes Research, Department of Cardiovascular Sciences, University of Leicester, Leicester LE1 5WW
    BMJ 341:c4229. 2010
    ..To investigate the independent effects of intake of fruit and vegetables on incidence of type 2 diabetes...
  87. ncbi request reprint Empowering patients with diabetes: a qualitative primary care study focusing on South Asians in Leicester, UK
    Margaret Stone
    Department of Health Sciences General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Leicester LE5 4PW, UK
    Fam Pract 22:647-52. 2005
    ..We aimed to explore the experience and attitudes of primary care patients with diabetes living in a UK community with a high proportion of South Asian patients of Indian origin, with particular reference to patient empowerment...
  88. doi request reprint Ethnic differences in body composition in adolescents
    Margaret A Stone
    Department of Health Sciences General Practice, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, United Kingdom
    Prim Care Diabetes 2:55-7. 2008
    ..Body fat percentage, assessed by bio-impedance, was higher in South Asians after adjustment for potential confounders...
  89. pmc Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: a cross-sectional study
    Laura J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Vasc Health Risk Manag 6:837-42. 2010
    ..A targeted screening program was carried out in a United Kingdom (UK) multiethnic population to identify those with abnormal glucose tolerance...
  90. doi request reprint Association of features of primary health care with coronary heart disease mortality
    Louis S Levene
    Department of Health Sciences, University of Leicester, 22 28 Princess Rd W, Leicester LE1 6TP, England
    JAMA 304:2028-34. 2010
    ..In England, with a universal access health system, coronary heart disease (CHD) mortality rates have decreased by more than two-fifths in the last decade, but variations in rates between local populations persist...
  91. pmc Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis
    Clare L Gillies
    Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester LE1 7RH
    BMJ 334:299. 2007
    ..To quantify the effectiveness of pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance...
  92. pmc Different strategies for screening and prevention of type 2 diabetes in adults: cost effectiveness analysis
    Clare L Gillies
    Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester LE1 7RH
    BMJ 336:1180-5. 2008
    ....
  93. pmc Dietary habits of young people attending secondary schools serving a multiethnic, inner-city community in the UK
    Margaret A Stone
    Department of Health Sciences General Practice, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Postgrad Med J 83:115-9. 2007
    ..Although South Asians in the UK have an increased risk of developing these conditions, detailed studies on their lifestyles including the dietary habits of young people are scarce...
  94. ncbi request reprint Identification of previously undiagnosed left ventricular systolic dysfunction: community screening using natriuretic peptides and electrocardiography
    Leong L Ng
    Department of Medicine and Therapeutics, Robert Kilpatrick, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Eur J Heart Fail 5:775-82. 2003
    ..We examined strategies to improve the positive predictive value of natriuretic peptides in screening for undiagnosed left ventricular systolic dysfunction (LVSD) in the community...
  95. doi request reprint Type 2 diabetes and cardiovascular disease in South Asians
    Nitin Gholap
    Department of Diabetes Research, University Hospitals of Leicester NHS Trust, Leicester, UK
    Prim Care Diabetes 5:45-56. 2011
    ..Finally the review makes recommendations on various measures including need for further research to tackle this serious health challenge facing the South Asian community...
  96. doi request reprint Clinical inertia in management of T2DM
    Azhar Zafar
    Department of Health Sciences, University of Leicester, United Kingdom
    Prim Care Diabetes 4:203-7. 2010
    ..Health care professionals must need to overcome clinical inertia and need to intensify therapy in an appropriate and timely manner...
  97. pmc Evaluating tools to support a new practical classification of diabetes: excellent control may represent misdiagnosis and omission from disease registers is associated with worse control
    N Hassan Sadek
    Department of Health Care Management and Policy, Surrey University, Guildford, UK Department of Health Sciences, University of Leicester, Leicester, UK
    Int J Clin Pract 66:874-82. 2012
    ..To conduct a service evaluation of usability and utility on-line clinical audit tools developed as part of a UK Classification of Diabetes project to improve the categorisation and ultimately management of diabetes...
  98. doi request reprint Incorrect and incomplete coding and classification of diabetes: a systematic review
    M A Stone
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 27:491-7. 2010
    ....
  99. doi request reprint Liraglutide - overview of the preclinical and clinical data and its role in the treatment of type 2 diabetes
    M J Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 13:207-20. 2011
    ..Liraglutide is also generally well tolerated with a low risk of hypoglycaemia. Liraglutide has recently been approved for marketing in Europe, Japan and the USA...
  100. ncbi request reprint Educational needs for blood pressure control in chronic kidney disease
    Jo Mason
    Department of Nephrology, University Hospitals of Leicester NHS Trust, Leicester, UK
    J Ren Care 33:134-8. 2007
    ..In people with chronic kidney disease, confusion can lead to a lack of motivation and negative views that need to be addressed through appropriate education and support...
  101. ncbi request reprint The prevalence of co-morbid depression in adults with Type 2 diabetes: a systematic review and meta-analysis
    S Ali
    University of Leicester, Leicester, UK
    Diabet Med 23:1165-73. 2006
    ..To conduct a systematic literature review in order to estimate the prevalence and odds ratio of clinically relevant depression in adults with Type 2 diabetes compared with those without...