K Khunti

Summary

Affiliation: University of Leicester
Country: UK

Publications

  1. ncbi A comparison of cost per case detected of screening strategies for Type 2 diabetes and impaired glucose regulation: modelling study
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, UK
    Diabetes Res Clin Pract 97:505-13. 2012
  2. ncbi Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? The DESMOND SMBG randomised controlled trial protocol
    Helen M Dallosso
    Diabetes Research Department, University Hospitals of Leicester NHS Trust, Leicester, UK
    BMC Fam Pract 13:18. 2012
  3. ncbi Validity of self-assessed waist circumference in a multi-ethnic UK population
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 29:404-9. 2012
  4. ncbi Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester LE1 6TP, UK
    BMJ 344:e2333. 2012
  5. ncbi The Reversal Intervention for Metabolic Syndrome (TRIMS) study: rationale, design, and baseline data
    Alison J Dunkley
    Department of Health Sciences, University of Leicester, Leicester, UK
    Trials 12:107. 2011
  6. ncbi Rationale and study design for a randomised controlled trial to reduce sedentary time in adults at risk of type 2 diabetes mellitus: project stand (Sedentary Time ANd diabetes)
    Emma G Wilmot
    Diabetes Research, Department of Cardiovascular Sciences, University of Leicester, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    BMC Public Health 11:908. 2011
  7. ncbi Randomised controlled trial of near-patient testing for glycated haemoglobin in people with type 2 diabetes mellitus
    Kamlesh Khunti
    Division of General Practice and Primary Health Care, Department of Health Sciences, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW
    Br J Gen Pract 56:511-7. 2006
  8. ncbi Disease management programme for secondary prevention of coronary heart disease and heart failure in primary care: a cluster randomised controlled trial
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, UK
    Heart 93:1398-405. 2007
  9. ncbi Physical activity and sedentary behaviours of South Asian and white European children in inner city secondary schools in the UK
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Fam Pract 24:237-44. 2007
  10. ncbi Effect of insulin glargine on glycaemic control and weight in obese and non-obese people with type 2 diabetes: data from the AT.LANTUS trial
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 12:683-8. 2010

Collaborators

Detail Information

Publications103 found, 100 shown here

  1. ncbi A comparison of cost per case detected of screening strategies for Type 2 diabetes and impaired glucose regulation: modelling study
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, UK
    Diabetes Res Clin Pract 97:505-13. 2012
    ..To determine a cost per case detected for different screening strategies for both Type 2 diabetes alone and in combination with impaired glucose regulation...
  2. ncbi Does self monitoring of blood glucose as opposed to urinalysis provide additional benefit in patients newly diagnosed with type 2 diabetes receiving structured education? The DESMOND SMBG randomised controlled trial protocol
    Helen M Dallosso
    Diabetes Research Department, University Hospitals of Leicester NHS Trust, Leicester, UK
    BMC Fam Pract 13:18. 2012
    ..However, what was unclear was whether a cheaper method of self-monitoring (such as urine glucose monitoring) could produce comparable benefit and patient acceptability for less cost...
  3. ncbi Validity of self-assessed waist circumference in a multi-ethnic UK population
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 29:404-9. 2012
    ..To investigate validity of waist circumference measurements obtained by self-report and self-measurement with non-verbal pictorial instructions among a multi-ethnic population...
  4. ncbi Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: three year follow-up of a cluster randomised controlled trial in primary care
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester LE1 6TP, UK
    BMJ 344:e2333. 2012
    ..To measure whether the benefits of a single education and self management structured programme for people with newly diagnosed type 2 diabetes mellitus are sustained at three years...
  5. ncbi The Reversal Intervention for Metabolic Syndrome (TRIMS) study: rationale, design, and baseline data
    Alison J Dunkley
    Department of Health Sciences, University of Leicester, Leicester, UK
    Trials 12:107. 2011
    ..This paper describes the rationale and design of the TRIMS study, including intervention development, and presents baseline data...
  6. ncbi Rationale and study design for a randomised controlled trial to reduce sedentary time in adults at risk of type 2 diabetes mellitus: project stand (Sedentary Time ANd diabetes)
    Emma G Wilmot
    Diabetes Research, Department of Cardiovascular Sciences, University of Leicester, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    BMC Public Health 11:908. 2011
    ..Project STAND (Sedentary Time ANd Diabetes) is a study which aims to reduce sedentary behaviour in younger adults at high risk of T2DM...
  7. ncbi Randomised controlled trial of near-patient testing for glycated haemoglobin in people with type 2 diabetes mellitus
    Kamlesh Khunti
    Division of General Practice and Primary Health Care, Department of Health Sciences, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW
    Br J Gen Pract 56:511-7. 2006
    ..Tight glycaemic control in people with type 2 diabetes can lead to a reduction in microvascular and possibly macrovascular complications. The use of near-patient (rapid) testing offers a potential method to improve glycaemic control...
  8. ncbi Disease management programme for secondary prevention of coronary heart disease and heart failure in primary care: a cluster randomised controlled trial
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, UK
    Heart 93:1398-405. 2007
    ..To evaluate the effect of a disease management programme for patients with coronary heart disease (CHD) and chronic heart failure (CHF) in primary care...
  9. ncbi Physical activity and sedentary behaviours of South Asian and white European children in inner city secondary schools in the UK
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Fam Pract 24:237-44. 2007
    ..Risk factors for cardiovascular disease in children often persist into adulthood. Low levels of physical activity are likely to be linked to the rise in obesity...
  10. ncbi Effect of insulin glargine on glycaemic control and weight in obese and non-obese people with type 2 diabetes: data from the AT.LANTUS trial
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 12:683-8. 2010
    ..To explore glucose lowering response to insulin initiation or switch to insulin glargine in obese and non-obese individuals with type 2 diabetes mellitus (T2DM) and to examine weight gain and hypoglycaemic episodes in this group...
  11. ncbi Glycaemic goals in patients with type 2 diabetes: current status, challenges and recent advances
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 12:474-84. 2010
    ..These new classes of therapy and other strategies outlined above could help clinicians to individualize treatment and help a greater proportion of patients to achieve long-term control of blood glucose...
  12. ncbi Screening for the metabolic syndrome using simple anthropometric measurements in south Asian and white Europeans: a population-based screening study. The Leicester Ethnic Atherosclerosis and Diabetes Risk (LEADER) Study
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester LE1 6TP, UK
    Prim Care Diabetes 4:25-32. 2010
    ..To estimate the prevalence of metabolic syndrome in a general population sample of south Asians and white Europeans and compare predictors of metabolic syndrome, using ethnic specific definitions of obesity...
  13. ncbi Quality of diabetes care in the UK: comparison of published quality-of-care reports with results of the Quality and Outcomes Framework for Diabetes
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 24:1436-41. 2007
    ....
  14. ncbi Primary prevention of type-2 diabetes and heart disease: action research in secondary schools serving an ethnically diverse UK population
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    J Public Health (Oxf) 30:30-7. 2008
    ..We aimed to identify barriers to healthy lifestyles and evaluate the effectiveness of an action research approach to lifestyle modification in secondary schools...
  15. ncbi Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with Type 2 diabetes: baseline data from the DESMOND randomized controlled trial
    K Khunti
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 25:1454-61. 2008
    ..To describe the characteristics of newly diagnosed people with Type 2 diabetes (T2DM) and compare these with published studies...
  16. ncbi Educational interventions for migrant South Asians with Type 2 diabetes: a systematic review
    K Khunti
    Department of Health Scienes, University of Leicester, University Hospital of Leicester NHS Trust, Leicester, UK
    Diabet Med 25:985-92. 2008
    ..To conduct a systematic review to determine the scope of published assessments of educational initiatives for South Asians with Type 2 diabetes living in Western countries and to consider the effectiveness of reported interventions...
  17. ncbi Approaches to the organization of multi-practice audits in primary health care in the UK
    K Khunti
    Eli Lilly National Clinical Audit Centre, Department of General Practice and Primary Health Care, University of Leicester, UK
    Int J Qual Health Care 11:221-6. 1999
    ..To investigate the approaches taken by audit groups in primary care in organizing multi-practice audits and to identify the strengths and weaknesses of the methods used...
  18. ncbi Heart failure in primary care: qualitative study of current management and perceived obstacles to evidence-based diagnosis and management by general practitioners
    Kamlesh Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Eur J Heart Fail 4:771-7. 2002
    ..Despite the evidence that appropriate treatment with angiotensin-converting enzyme inhibitors can improve morbidity, primary care studies show that patients with heart failure are incorrectly diagnosed and inadequately treated...
  19. ncbi Effect of systematic review of medication by general practitioner on drug consumption among nursing-home residents
    K Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, UK
    Age Ageing 29:451-3. 2000
    ..nursing-home patients usually have many medical problems and often take many drugs. They are therefore at risk from drug side effects and interactions...
  20. ncbi Systematic review of open access echocardiography for primary care
    Kamlesh Khunti
    Department of Health Sciences, Division of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Eur J Heart Fail 6:79-83. 2004
    ..Suspected heart failure comprises the majority of primary care referrals for open access echocardiography. There is lack of rigorously controlled studies to support widespread establishment of open access echocardiography services...
  21. ncbi Referral for autopsies: analysis of 651 consecutive deaths in one general practice
    K Khunti
    Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, Leicester, UK
    Postgrad Med J 76:415-6. 2000
    ..Better education and communication between general practitioners, hospital clinicians, pathologists, and coroners may increase the rate of autopsies...
  22. ncbi Who looks after people with diabetes: primary or secondary care?
    K Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, UK
    J R Soc Med 93:183-6. 2000
    ..This survey revealed large variations in delivery of general-practice diabetes care that need to be addressed by better organization and funding...
  23. ncbi Collation and comparison of multi-practice audit data: prevalence and treatment of known diabetes mellitus
    K Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital
    Br J Gen Pract 49:375-9. 1999
    ..Despite the large number of studies, previous estimations of prevalence and treatment have been carried out on relatively small numbers of patients, and then in only a few practices in single geographical regions...
  24. ncbi Accuracy of a 12-lead electrocardiogram in screening patients with suspected heart failure for open access echocardiography: a systematic review and meta-analysis
    K Khunti
    Department of Health Sciences, Division of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Leicester, UK
    Eur J Heart Fail 6:571-6. 2004
    ..Primary outcome measures were sensitivity and specificity, meta-analysed simultaneously to produce a Summary Receiver Operating Characteristic (SROC) curve...
  25. ncbi Coronary heart disease in people of south-Asian origin
    Kamlesh Khunti
    Department of Health Sciences, University of Leicester, Leicester LE5 4PW, UK
    Lancet 364:2077-8. 2004
  26. ncbi Diagnosis of patients with chronic heart failure in primary care: usefulness of history, examination, and investigations
    K Khunti
    Department of General Practice and Primary Health Care, University of Leicester, Leicester General Hospital
    Br J Gen Pract 50:50-4. 2000
    ..These should include an electrocardiogram and, ideally, an echocardiogram. Further research is also needed on the usefulness of signs and symptoms in primary care, as most studies of heart failure have been conducted in secondary care...
  27. ncbi Features of primary care associated with variations in process and outcome of care of people with diabetes
    K Khunti
    Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, Leicester
    Br J Gen Pract 51:356-60. 2001
    ..However, these studies have been conducted in single geographical areas and involved only small numbers of practices...
  28. ncbi Intensive multifactorial intervention improves modelled coronary heart disease risk in screen-detected Type 2 diabetes mellitus: a cluster randomized controlled trial
    D R Webb
    Department of Cardiovascular Sciences, Leicester Royal Infirmary, University of Leicester, Leicester, UK
    Diabet Med 29:531-40. 2012
    ..To compare the effects of intensive multifactorial cardiovascular risk intervention with standard care in screen-detected Type 2 diabetes...
  29. ncbi Levels of physical activity and relationship with markers of diabetes and cardiovascular disease risk in 5474 white European and South Asian adults screened for type 2 diabetes
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, LE3 9QP, UK
    Prev Med 51:290-4. 2010
    ..Investigate levels of physical activity and their association with health in a white European (WE) and South Asian (SA) population...
  30. ncbi Insulin initiation and management in people with Type 2 diabetes in an ethnically diverse population: the healthcare provider perspective
    N Patel
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 29:1311-6. 2012
    ..To explore barriers to prescribing of insulin, particularly delays in initiation, from the perspective of healthcare professionals involved in managing Type 2 diabetes in a multi-ethnic setting...
  31. ncbi Detection of impaired glucose regulation and/or type 2 diabetes mellitus, using primary care electronic data, in a multiethnic UK community setting
    L J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetologia 55:959-66. 2012
    ..The aim of this study was to develop and validate a score for detecting the glycaemic categories of impaired glucose regulation (IGR) and type 2 diabetes using the WHO 2011 diagnostic criteria...
  32. ncbi Association of cardiac and non-cardiac chronic disease comorbidity on glycaemic control in a multi-ethnic population with type 1 and type 2 diabetes
    R L Mehta
    Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    Postgrad Med J 87:763-8. 2011
    ....
  33. ncbi The association between anxiety and measures of glycaemia in a population-based diabetes screening programme
    N Aujla
    Department of Health Sciences Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabet Med 28:785-8. 2011
    ..To investigate associations between anxiety and measures of glycaemia in a White European and South Asian population attending community-based diabetes screening...
  34. ncbi Near patient testing for glycated haemoglobin in people with Type 2 diabetes mellitus managed in primary care: acceptability and satisfaction
    M A Stone
    Department of Health Sciences, University of Leicester, Leicester General Hospital, Leicester, UK
    Diabet Med 24:792-5. 2007
    ..To assess the acceptability of and satisfaction with near patient testing for glycated haemoglobin in primary care in patients and health professionals...
  35. ncbi Rationale and design of the ADDITION-Leicester study, a systematic screening programme and randomised controlled trial of multi-factorial cardiovascular risk intervention in people with type 2 diabetes mellitus detected by screening
    D R Webb
    Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, UK
    Trials 11:16. 2010
    ..Here we describe the rationale and methods of a systematic community screening programme and randomised controlled trial of cardiovascular risk management within a UK multiethnic setting (ADDITION-Leicester)...
  36. ncbi The Pre-diabetes Risk Education and Physical Activity Recommendation and Encouragement (PREPARE) programme study: are improvements in glucose regulation sustained at 2 years?
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabet Med 28:1268-71. 2011
    ..To determine whether improvements in glucose regulation following the PREPARE structured education programme were sustained at 24 months...
  37. ncbi Features of primary health care teams associated with successful quality improvement of diabetes care: a qualitative study
    K Stevenson
    Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, Leicester, UK
    Fam Pract 18:21-6. 2001
    ..Experimental studies are required to determine whether the development of teamwork enables practice teams to identify and overcome systematically the obstacles to improved quality of patient care that face them...
  38. ncbi The Leicester Risk Assessment score for detecting undiagnosed Type 2 diabetes and impaired glucose regulation for use in a multiethnic UK setting
    L J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 27:887-95. 2010
    ..To date no risk assessment scores that can be completed by a lay person have been developed and validated specifically for multiethnic populations in the UK...
  39. ncbi Effectiveness of interventions for reducing diabetes and cardiovascular disease risk in people with metabolic syndrome: systematic review and mixed treatment comparison meta-analysis
    A J Dunkley
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 14:616-25. 2012
    ..To review the evidence on interventions for reversing metabolic syndrome or preventing development of type 2 diabetes and cardiovascular disease in people with metabolic syndrome...
  40. ncbi A simple strategy for screening for glucose intolerance, using glycated haemoglobin, in individuals admitted with acute coronary syndrome
    N Gholap
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 29:838-43. 2012
    ....
  41. ncbi The potential impact of using glycated haemoglobin as the preferred diagnostic tool for detecting Type 2 diabetes mellitus
    S A Mostafa
    Division of Diabetes and Endocrinology, Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, UK
    Diabet Med 27:762-9. 2010
    ..The aim of this study was to examine the potential impact of the preferred use of HbA(1c) as a diagnostic tool on the prevalence and phenotype of T2DM...
  42. ncbi The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: a comparison of two screening tools
    N Aujla
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 27:896-905. 2010
    ..An additional aim was to further explore associations of depressive symptoms with impaired glucose regulation (IGR) and Type 2 diabetes mellitus (Type2 DM)...
  43. ncbi Impact of metabolic indices on central artery stiffness: independent association of insulin resistance and glucose with aortic pulse wave velocity
    D R Webb
    Diabetes and Vascular Research Group, Department of Cardiovascular Sciences, University of Leicester, Leicester LE1 5WW, UK
    Diabetologia 53:1190-8. 2010
    ..We used carotid-femoral pulse wave velocity ((cf)PWV) to quantify independent associations of fasting glucose, post-challenge glucose and derived insulin resistance (HOMA-IR) with aortic stiffness...
  44. ncbi Contrasting cardiovascular risk profiles and prescribed cardio-protective therapies in newly-diagnosed type 2 diabetes identified through screening and standard practice
    D R Webb
    Department of Cardiovascular Sciences, University of Leicester, UK
    Diabetes Res Clin Pract 91:280-5. 2011
    ..The cardiovascular risk profile of screen-detected (SD) T2DM is ill defined and has not been compared to conventional newly diagnosed (CD) cases...
  45. ncbi Inequalities in provision of systematic care for patients with diabetes
    K Khunti
    Clinical Governance Research and Development Unit, Department of General Practice and Primary Health Care, University of Leicester, Leicester, UK
    Fam Pract 18:27-32. 2001
    ..The results of this survey will be valuable to primary care groups and organizations responsible for commissioning diabetes services...
  46. ncbi The effect of increased ambulatory activity on markers of chronic low-grade inflammation: evidence from the PREPARE programme randomized controlled trial
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, UK School of Sport and Exercise Sciences, Loughborough University, UK
    Diabet Med 27:1256-63. 2010
    ..To investigate whether an exercise intervention programme, with or without pedometer use, is effective at reducing chronic low-grade inflammation in those with impaired glucose tolerance...
  47. ncbi A systematic review and mixed treatment comparison of pharmacological interventions for the treatment of obesity
    L J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Obes Rev 13:483-98. 2012
    ..Those interventions which have now been withdrawn from use (sibutramine and rimonabant) seem to be the most effective, implying that there may be a place in clinical practice for similar drugs if side effects could be avoided...
  48. ncbi Preventing type 2 diabetes: can we make the evidence work?
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, UK
    Postgrad Med J 85:475-80. 2009
    ..This article highlights findings from diabetes prevention programmes and discusses key issues involved in translating research into practice...
  49. ncbi Impact of comorbid diabetes on quality of life and perception of angina pain in people with angina registered with general practitioners in the UK
    M A Stone
    Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester LE1 6TP, UK
    Qual Life Res 17:887-94. 2008
    ..To investigate the impact of comorbid diabetes on general and angina-related quality of life (QoL) in people with angina...
  50. ncbi Insulin glargine and its role in glycaemic management of Type 2 diabetes
    M A Elrishi
    University Hospitals of Leicester NHS Trust, Department of Diabetes and Endocrinology, Level 1, Victoria Building, Leicester Royal Infirmary, Infirmary Square, Leicester, LE1 5WW, UK
    Expert Opin Drug Metab Toxicol 4:1099-110. 2008
    ..Insulin glargine (Lantus) was the first recombinant-DNA long-acting insulin analogue to be licensed for use in the treatment of diabetes mellitus...
  51. ncbi Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis
    E G Wilmot
    Department of Cardiovascular Sciences, University of Leicester, Leicester Diabetes Centre, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Diabetologia 55:2895-905. 2012
    ..We conducted a systematic review and meta-analysis to examine the association of sedentary time with diabetes, cardiovascular disease and cardiovascular and all-cause mortality...
  52. ncbi Initiation of insulin glargine in suboptimally controlled patients with type 2 diabetes: sub-analysis of the AT.LANTUS trial comparing treatment outcomes in subjects from primary and secondary care in the UK
    M Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 9:706-13. 2007
    ....
  53. ncbi Diagnostic performance of using one- or two-HbA1c cut-point strategies to detect undiagnosed type 2 diabetes and impaired glucose regulation within a multi-ethnic population
    S A Mostafa
    Division of Diabetes and Endocrinology, Department of Cardiovascular Sciences, Level 0, Victoria Building, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
    Diab Vasc Dis Res 10:84-92. 2013
    ..5% (48 mmol/mol) or (b) two HbA1c thresholds where the first cut-point 'rules out' and the second 'rules in' diabetes. HbA1c values in between the thresholds require confirmatory glucose testing for diagnosis...
  54. ncbi Study of Once Daily Levemir (SOLVE™): insights into the timing of insulin initiation in people with poorly controlled type 2 diabetes in routine clinical practice
    K Khunti
    Department of Health Sciences, University of Leicester, 4301 Connecticut Ave NW, Washington, DC 20008, USA
    Diabetes Obes Metab 14:654-61. 2012
    ..The aim of this analysis is to determine the timing of insulin initiation in routine clinical practice, especially in relation to glycaemic control and use of oral antidiabetic drugs (OADs)...
  55. ncbi Insulin management in overweight or obese type 2 diabetes patients: the role of insulin glargine
    M Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 10:42-9. 2008
    ..Retrospective subanalyses of earlier trials and ongoing studies would shed further light on the impact of insulin therapy in obese people with T2DM in addition to determination of optimal therapeutic strategies...
  56. ncbi Patient safety systems in the primary health care of diabetes—a story of missed opportunities?
    N Taub
    National Institute of Health Research Collaboration for Leadership in Applied Research and Care for Leicestershire, Northamptonshire and Rutland, Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester, UK
    Diabet Med 27:1322-6. 2010
    ..The aims of this study were to review the current state of research into patient safety systems for people with diabetes in primary care...
  57. ncbi The DESMOND educational intervention
    M J Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Chronic Illn 4:38-40. 2008
  58. ncbi The role of physical activity in the management of type 2 diabetes mellitus
    T Yates
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Postgrad Med J 85:129-33. 2009
    ..This review provides an overview of the evidence surrounding the relative importance of physical activity and weight loss in the management of T2DM and highlights key ways of initiating physical activity behaviour change...
  59. ncbi Fruit and vegetable intake and the association with glucose parameters: a cross-sectional analysis of the Let's Prevent Diabetes Study
    P Carter
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Eur J Clin Nutr 67:12-7. 2013
    ..Fruit and vegetables may confer benefit via their antioxidant capacity, thus we also measured urinary F(2)-isoprostanes as a marker for oxidative stress...
  60. ncbi Investigating endothelial activation and oxidative stress in relation to glycaemic control in a multiethnic population
    E M Brady
    Department of Diabetes Research, University Hospitals of Leicester, NHS Trust, Leicester LE5 4PW, UK
    Exp Diabetes Res 2012:386041. 2012
    ..An exploration of ethnic differences in measures of oxidative stress and endothelial activation in relation to known cardiovascular risk factors within South Asians (SA) and White Europeans (WE) residing in the UK...
  61. ncbi Implementation of the automated Leicester Practice Risk Score in two diabetes prevention trials provides a high yield of people with abnormal glucose tolerance
    L J Gray
    Department of Health Sciences, University of Leicester, Leicester Diabetes Centre Broadleaf, Leicester General Hospital, Gwendolen Road, Leicester, LE5 4PW, UK
    Diabetologia 55:3238-44. 2012
    ..The aim of this study was to determine the yield from the LPRS when applied in two diabetes prevention trials...
  62. ncbi Quality of secondary prevention measures in TIA patients: a retrospective cohort study
    K E Lager
    Department of Health Sciences, University of Leicester, 22 28 Princess Road West, Leicester LE1 6TP, UK
    Postgrad Med J 88:305-11. 2012
    ..This study aimed to investigate the quality of secondary stroke prevention in primary care following diagnosis of TIA in a specialist clinic...
  63. ncbi An update on exenatide, a novel therapeutic option for patients with type 2 diabetes
    W Crasto
    University Hospitals of Leicester, Leicester, UK
    Drugs Today (Barc) 47:839-56. 2011
    ..Meanwhile, the results from long-term studies to assess cardiovascular benefits with exenatide therapy are eagerly awaited...
  64. ncbi Recent advances in the management of type 2 diabetes mellitus: a review
    B T Srinivasan
    Department of Diabetes Research, University Hospitals of Leicester NHS Trust, Leicester, UK
    Postgrad Med J 84:524-31. 2008
    ..This review also includes new agents in the area of weight loss that may have a positive effect for glucose management-for example, rimonabant...
  65. ncbi Searching for the right outcome? A systematic review and meta-analysis of controlled trials using carotid intima-media thickness or pulse wave velocity to infer antiatherogenic properties of thiazolidinediones
    D R Webb
    Department of Cardiovascular Sciences, Victoria Building, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    Diabetes Obes Metab 12:124-32. 2010
    ..The aim was to provide an evidence-based overview of TZD intervention studies using markers prospectively linked to vascular outcome in type 2 diabetes...
  66. ncbi Identification of previously undiagnosed left ventricular systolic dysfunction: community screening using natriuretic peptides and electrocardiography
    Leong L Ng
    Department of Medicine and Therapeutics, Robert Kilpatrick, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Eur J Heart Fail 5:775-82. 2003
    ..We examined strategies to improve the positive predictive value of natriuretic peptides in screening for undiagnosed left ventricular systolic dysfunction (LVSD) in the community...
  67. ncbi Dietary habits of young people attending secondary schools serving a multiethnic, inner-city community in the UK
    Margaret A Stone
    Department of Health Sciences General Practice, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, UK
    Postgrad Med J 83:115-9. 2007
    ..Although South Asians in the UK have an increased risk of developing these conditions, detailed studies on their lifestyles including the dietary habits of young people are scarce...
  68. ncbi Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis
    Clare L Gillies
    Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester LE1 7RH
    BMJ 334:299. 2007
    ..To quantify the effectiveness of pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance...
  69. ncbi Waist circumference measurement: knowledge, attitudes and barriers in patients and practitioners in a multi-ethnic population
    Alison J Dunkley
    Department of Health Sciences, University of Leicester and University Hospitals of Leicester NHS Trust, UK
    Fam Pract 26:365-71. 2009
    ..The primary health care team are ideally suited to screen for people at high risk of glucose intolerance and increased cardiovascular risk using waist circumference measurement (WCM)...
  70. ncbi Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: a cross-sectional study
    Laura J Gray
    Department of Health Sciences, University of Leicester, Leicester, UK
    Vasc Health Risk Manag 6:837-42. 2010
    ..A targeted screening program was carried out in a United Kingdom (UK) multiethnic population to identify those with abnormal glucose tolerance...
  71. ncbi Ethnic differences in body composition in adolescents
    Margaret A Stone
    Department of Health Sciences General Practice, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester LE5 4PW, United Kingdom
    Prim Care Diabetes 2:55-7. 2008
    ..Body fat percentage, assessed by bio-impedance, was higher in South Asians after adjustment for potential confounders...
  72. ncbi Effectiveness of a pragmatic education program designed to promote walking activity in individuals with impaired glucose tolerance: a randomized controlled trial
    Thomas Yates
    Department of Cardiovascular Sciences, University of Leicester, U K
    Diabetes Care 32:1404-10. 2009
    ..This result is likely to have important implications for future primary care-based diabetes prevention initiatives...
  73. ncbi Different strategies for screening and prevention of type 2 diabetes in adults: cost effectiveness analysis
    Clare L Gillies
    Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, Leicester LE1 7RH
    BMJ 336:1180-5. 2008
    ....
  74. ncbi Community screening for left ventricular systolic dysfunction using plasma and urinary natriuretic peptides
    Leong L Ng
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, United Kingdom
    J Am Coll Cardiol 45:1043-50. 2005
    ..We sought to compare urinary and plasma N-terminal pro-brain natriuretic peptide (N-BNP) in left ventricular systolic dysfunction (LVSD) diagnosis...
  75. ncbi Is having a family history of type 2 diabetes or cardiovascular disease a predictive factor for metabolic syndrome?
    Alison J Dunkley
    Department of Health Sciences, University of Leicester, Leicester, United Kingdom
    Prim Care Diabetes 3:49-56. 2009
    ..Also, to establish if the association is different for South Asians compared to White Europeans, and for obese compared to non-obese individuals...
  76. ncbi Empowering patients with diabetes: a qualitative primary care study focusing on South Asians in Leicester, UK
    Margaret Stone
    Department of Health Sciences General Practice and Primary Health Care, University of Leicester, Leicester General Hospital, Leicester LE5 4PW, UK
    Fam Pract 22:647-52. 2005
    ..We aimed to explore the experience and attitudes of primary care patients with diabetes living in a UK community with a high proportion of South Asian patients of Indian origin, with particular reference to patient empowerment...
  77. ncbi The prevalence of depression in white-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus
    Navneet Aujla
    Department of Health Sciences, University of Leicester, Leicester, United Kingdom
    PLoS ONE 4:e7755. 2009
    ....
  78. ncbi Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis
    Patrice Carter
    Diabetes Research, Department of Cardiovascular Sciences, University of Leicester, Leicester LE1 5WW
    BMJ 341:c4229. 2010
    ..To investigate the independent effects of intake of fruit and vegetables on incidence of type 2 diabetes...
  79. ncbi A cross sectional survey of secondary prevention measures in patients with peripheral arterial disease in primary care
    Alison Dunkley
    Division of General Practice and Primary Health Care, Department of Health Sciences, University of Leicester, Leicester General Hospital, Leicester, UK
    Postgrad Med J 83:602-5. 2007
    ..The National Service Framework for coronary heart disease (CHD) defines standards for the secondary prevention of cardiovascular disease in at risk individuals, including those with peripheral arterial disease (PAD)...
  80. ncbi Association of features of primary health care with coronary heart disease mortality
    Louis S Levene
    Department of Health Sciences, University of Leicester, 22 28 Princess Rd W, Leicester LE1 6TP, England
    JAMA 304:2028-34. 2010
    ..In England, with a universal access health system, coronary heart disease (CHD) mortality rates have decreased by more than two-fifths in the last decade, but variations in rates between local populations persist...
  81. ncbi Type 2 diabetes and cardiovascular disease in South Asians
    Nitin Gholap
    Department of Diabetes Research, University Hospitals of Leicester NHS Trust, Leicester, UK
    Prim Care Diabetes 5:45-56. 2011
    ..Finally the review makes recommendations on various measures including need for further research to tackle this serious health challenge facing the South Asian community...
  82. ncbi Clinical inertia in management of T2DM
    Azhar Zafar
    Department of Health Sciences, University of Leicester, United Kingdom
    Prim Care Diabetes 4:203-7. 2010
    ..Health care professionals must need to overcome clinical inertia and need to intensify therapy in an appropriate and timely manner...
  83. ncbi The association between body mass index and health-related quality of life: influence of ethnicity on this relationship
    C McDonough
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 15:342-8. 2013
    ..The influence of ethnicity on this relationship has less frequently been considered. We aimed to explore the relationship between body mass index (BMI) and HRQL in a mixed population of White European (WE) and South Asian (SA) ethnicity...
  84. ncbi Evaluating tools to support a new practical classification of diabetes: excellent control may represent misdiagnosis and omission from disease registers is associated with worse control
    N Hassan Sadek
    Department of Health Care Management and Policy, Surrey University, Guildford, UK Department of Health Sciences, University of Leicester, Leicester, UK
    Int J Clin Pract 66:874-82. 2012
    ..To conduct a service evaluation of usability and utility on-line clinical audit tools developed as part of a UK Classification of Diabetes project to improve the categorisation and ultimately management of diabetes...
  85. ncbi Incorrect and incomplete coding and classification of diabetes: a systematic review
    M A Stone
    Department of Health Sciences, University of Leicester, Leicester, UK
    Diabet Med 27:491-7. 2010
    ....
  86. ncbi Liraglutide - overview of the preclinical and clinical data and its role in the treatment of type 2 diabetes
    M J Davies
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Diabetes Obes Metab 13:207-20. 2011
    ..Liraglutide is also generally well tolerated with a low risk of hypoglycaemia. Liraglutide has recently been approved for marketing in Europe, Japan and the USA...
  87. ncbi Educational needs for blood pressure control in chronic kidney disease
    Jo Mason
    Department of Nephrology, University Hospitals of Leicester NHS Trust, Leicester, UK
    J Ren Care 33:134-8. 2007
    ..In people with chronic kidney disease, confusion can lead to a lack of motivation and negative views that need to be addressed through appropriate education and support...
  88. ncbi The prevalence of co-morbid depression in adults with Type 2 diabetes: a systematic review and meta-analysis
    S Ali
    University of Leicester, Leicester, UK
    Diabet Med 23:1165-73. 2006
    ..To conduct a systematic literature review in order to estimate the prevalence and odds ratio of clinically relevant depression in adults with Type 2 diabetes compared with those without...
  89. ncbi Automated identification of miscoded and misclassified cases of diabetes from computer records
    A R Sadek
    Division of Population Health Sciences and Education, St George s University of London, London, UK
    Diabet Med 29:410-4. 2012
    ..To develop a computer processable algorithm, capable of running automated searches of routine data that flag miscoded and misclassified cases of diabetes for subsequent clinical review...
  90. ncbi Miscoding, misclassification and misdiagnosis of diabetes in primary care
    S de Lusignan
    Department of Health Care Management and Policy, Faculty of Business, Economics and Law, University of Surrey, Guildford, UK
    Diabet Med 29:181-9. 2012
    ..To determine the effectiveness of self-audit tools designed to detect miscoding, misclassification and misdiagnosis of diabetes in primary care...
  91. ncbi Psychological morbidity and illness appraisals of patients with cardiac and non-cardiac chest pain attending a rapid access chest pain clinic: a longitudinal cohort study
    N Robertson
    School of Psychology, University of Leicester, UK
    Heart 94:e12. 2008
    ..To assess the psychological morbidity and illness beliefs in newly referred patients with chest pain, and to compare the psychological morbidity of patients with pain of cardiac origin with that of patients with pain of non-cardiac origin...
  92. ncbi Mixed comparison of stroke prevention treatments in individuals with nonrheumatic atrial fibrillation
    Nicola J Cooper
    Centre for Biostatistics and Genetic Epidemiology, Department of Health Sciences, University of Leicester, 22-28 Princess Road West, Leicester, England
    Arch Intern Med 166:1269-75. 2006
    ....
  93. ncbi Waiting for diabetes: perceptions of people with pre-diabetes: a qualitative study
    Jacqui Troughton
    University Hospitals of Leicester NHS Trust, United Kingdom
    Patient Educ Couns 72:88-93. 2008
    ....
  94. ncbi The EUCCLID study: proposed European study on care and complications in people with type 2 diabetes in primary care
    Inge W G Bobbink
    Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Prim Care Diabetes 1:167-71. 2007
    ..We will also determine primary care physician's attitudes, behaviour and perception of barriers to deliver effective diabetes care...
  95. ncbi Prevention and cure of type 2 diabetes. General practitioners are treating more cases of diabetes
    Azeem Majeed
    University College London, London WC1H 9QU
    BMJ 325:965. 2002
  96. ncbi Managing heart failure in primary care: first steps in implementing the National Service Framework
    Shamini Gnani
    Office for National Statistics, 1 Drummond Gate, London SW1V 2QQ
    J Public Health (Oxf) 26:42-7. 2004
    ..We examined how patients with heart failure were investigated and treated compared with NSF standards, and explored the current constraints in improving the care of these patients...
  97. ncbi Shared care guidelines and protocols in the United kingdom
    Azeem Majeed
    Department of Primary Care and Social Medicine, Imperial College Faculty of Medicine, London, United Kingdom
    J Ambul Care Manage 31:239-43. 2008
    ....
  98. ncbi Ethnic disparities in diabetes management and pay-for-performance in the UK: the Wandsworth Prospective Diabetes Study
    Christopher Millett
    Wandsworth Primary Care Research Centre, Wandsworth Primary Care Trust, London, United Kingdom
    PLoS Med 4:e191. 2007
    ..We examined disparities in management of people with diabetes and intermediate clinical outcomes within a multiethnic population in primary care before and after the introduction of the new contract in April 2004...
  99. ncbi Diabetes Education and Self-Management for Ongoing and Newly Diagnosed (DESMOND): process modelling of pilot study
    T Chas Skinner
    School of Psychology and School of Medicine, University of Southampton, Southampton, UK
    Patient Educ Couns 64:369-77. 2006
    ..To determine the effects of a structured education program on illness beliefs, quality of life and physical activity in people newly diagnosed with Type 2 diabetes...
  100. ncbi Ethnicity and quality of diabetes care in a health system with universal coverage: population-based cross-sectional survey in primary care
    Jeremy Gray
    Wandsworth Primary Care Research Centre, Wandsworth Primary Care Trust, London, SW11 6HN, UK
    J Gen Intern Med 22:1317-20. 2007
    ..The UK has a universal health care system that is free at the point of access. Over the past decade, the UK government has implemented an ambitious agenda of quality improvement initiatives in chronic disease management...
  101. ncbi Diabetes prevalence, process of care and outcomes in relation to practice size, caseload and deprivation: national cross-sectional study in primary care
    Christopher Millett
    Department of Primary Care and Social Medicine, Imperial College, Reynolds Building, St Dunstan s Road, London W6 8RP, UK
    J R Soc Med 100:275-83. 2007
    ..To examine the association between practice list size, deprivation and the quality of care of patients with diabetes...