Tarnjit K Khera

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc Tumour necrosis factor-mediated macrophage activation in the target organ is critical for clinical manifestation of uveitis
    T K Khera
    School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK
    Clin Exp Immunol 168:165-77. 2012
  2. ncbi request reprint Fragile X-related protein FXR1 controls post-transcriptional suppression of lipopolysaccharide-induced tumour necrosis factor-alpha production by transforming growth factor-beta1
    Tarnjit K Khera
    Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, UK
    FEBS J 277:2754-65. 2010
  3. doi request reprint Mechanisms of TNFα regulation in uveitis: focus on RNA-binding proteins
    Tarnjit K Khera
    School of Cellular and Molecular Medicine, University Walk, Bristol, UK
    Prog Retin Eye Res 29:610-21. 2010
  4. ncbi request reprint Tissue-resident exhausted effector memory CD8+ T cells accumulate in the retina during chronic experimental autoimmune uveoretinitis
    Joanne Boldison
    School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, United Kingdom
    J Immunol 192:4541-50. 2014

Collaborators

Detail Information

Publications4

  1. pmc Tumour necrosis factor-mediated macrophage activation in the target organ is critical for clinical manifestation of uveitis
    T K Khera
    School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK
    Clin Exp Immunol 168:165-77. 2012
    ..We conclude that sTNF is required for inflammatory cell infiltration into target tissue, but at the tissue site inhibition of both sTNF and tmTNF is required to inhibit macrophage activation and to protect from tissue damage...
  2. ncbi request reprint Fragile X-related protein FXR1 controls post-transcriptional suppression of lipopolysaccharide-induced tumour necrosis factor-alpha production by transforming growth factor-beta1
    Tarnjit K Khera
    Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, UK
    FEBS J 277:2754-65. 2010
    ..In summary, TGF-beta1 opposes LPS-induced stabilization of TNF-alpha mRNA and reduces the amount of TNF-alpha protein, through induction of expression of the mRNA-binding protein FXR1...
  3. doi request reprint Mechanisms of TNFα regulation in uveitis: focus on RNA-binding proteins
    Tarnjit K Khera
    School of Cellular and Molecular Medicine, University Walk, Bristol, UK
    Prog Retin Eye Res 29:610-21. 2010
    ..The study of mRNA stability remains essential for the understanding of intracellular regulatory pathways and molecular mechanisms of pathology for infection, inflammation and degeneration...
  4. ncbi request reprint Tissue-resident exhausted effector memory CD8+ T cells accumulate in the retina during chronic experimental autoimmune uveoretinitis
    Joanne Boldison
    School of Cellular and Molecular Medicine, University of Bristol, Bristol BS8 1TD, United Kingdom
    J Immunol 192:4541-50. 2014
    ..They are phenotypically distinct from peripheral CD8(+) T cells and provide local signals within the tissue by expression of inhibitory receptors such as programmed death 1 that limit persistent inflammation. ..