Sohail Q Khan

Summary

Affiliation: University of Leicester
Country: UK

Publications

  1. ncbi Urotensin II is raised in acute myocardial infarction and low levels predict risk of adverse clinical outcome in humans
    Sohail Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Int J Cardiol 117:323-8. 2007
  2. doi N-terminal pro-B-type natriuretic peptide complements the GRACE risk score in predicting early and late mortality following acute coronary syndrome
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Leicester Royal Infirmary, Leicester, UK
    Clin Sci (Lond) 117:31-9. 2009
  3. doi Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarction
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Eur Heart J 30:1057-65. 2009
  4. doi Plasma N-terminal B-Type natriuretic peptide as an indicator of long-term survival after acute myocardial infarction: comparison with plasma midregional pro-atrial natriuretic peptide: the LAMP (Leicester Acute Myocardial Infarction Peptide) study
    Sohail Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Clinical Sciences Building, Leicester Royal Infirmary, Leicester, United Kingdom
    J Am Coll Cardiol 51:1857-64. 2008
  5. ncbi C-terminal pro-endothelin-1 offers additional prognostic information in patients after acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) Study
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Leicester Royal Infirmary, Leicester, UK
    Am Heart J 154:736-42. 2007
  6. ncbi N-terminal pro-B-type natriuretic peptide is better than TIMI risk score at predicting death after acute myocardial infarction
    S Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, UK
    Heart 94:40-3. 2008
  7. ncbi Prognostic value of midregional pro-adrenomedullin in patients with acute myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) study
    Sohail Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, United Kingdom
    J Am Coll Cardiol 49:1525-32. 2007
  8. pmc Myeloperoxidase aids prognostication together with N-terminal pro-B-type natriuretic peptide in high-risk patients with acute ST elevation myocardial infarction
    Sohail Q Khan
    Department of Cardiovascular Medicine, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester, UK
    Heart 93:826-31. 2007
  9. ncbi Myotrophin is a more powerful predictor of major adverse cardiac events following acute coronary syndrome than N-terminal pro-B-type natriuretic peptide
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Clin Sci (Lond) 112:251-6. 2007
  10. ncbi C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) study
    Sohail Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Circulation 115:2103-10. 2007

Detail Information

Publications19

  1. ncbi Urotensin II is raised in acute myocardial infarction and low levels predict risk of adverse clinical outcome in humans
    Sohail Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Int J Cardiol 117:323-8. 2007
    ..We also compared UII to N terminal pro B type natriuretic peptide (NT-BNP) to evaluate whether levels of UII can be used to predict the risk of adverse clinical outcome (ACO)...
  2. doi N-terminal pro-B-type natriuretic peptide complements the GRACE risk score in predicting early and late mortality following acute coronary syndrome
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Leicester Royal Infirmary, Leicester, UK
    Clin Sci (Lond) 117:31-9. 2009
    ..85] and 6-month mortality (AUC, 0.81). NT-proBNP gives complementary information to the GRACE risk score for predicting early and late mortality. The inclusion of the NT-proBNP blood test is useful in risk-stratifying patients after ACS...
  3. doi Growth differentiation factor-15 as a prognostic marker in patients with acute myocardial infarction
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Eur Heart J 30:1057-65. 2009
    ..We were interested to see if GDF-15 could provide long-term prognostic value in post-AMI patients. We compared GDF-15 with N-terminal pro-B-type natriuretic peptide (NT-proBNP)...
  4. doi Plasma N-terminal B-Type natriuretic peptide as an indicator of long-term survival after acute myocardial infarction: comparison with plasma midregional pro-atrial natriuretic peptide: the LAMP (Leicester Acute Myocardial Infarction Peptide) study
    Sohail Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Clinical Sciences Building, Leicester Royal Infirmary, Leicester, United Kingdom
    J Am Coll Cardiol 51:1857-64. 2008
    ..Our aim was to assess the prognostic value of midregional pro-atrial natriuretic peptide (MR-proANP) in patients after acute myocardial infarction (AMI)...
  5. ncbi C-terminal pro-endothelin-1 offers additional prognostic information in patients after acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) Study
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Leicester Royal Infirmary, Leicester, UK
    Am Heart J 154:736-42. 2007
    ..We investigated the cardiovascular prognostic value post-AMI of CT-proET-1 and compared it to N-terminal pro-B-type natriuretic peptide (NTproBNP), a marker of death and HF...
  6. ncbi N-terminal pro-B-type natriuretic peptide is better than TIMI risk score at predicting death after acute myocardial infarction
    S Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, UK
    Heart 94:40-3. 2008
    ..N-terminal pro-B-type natriuretic peptide (NTproBNP) has also been found to be useful in predicting mortality following STEMI...
  7. ncbi Prognostic value of midregional pro-adrenomedullin in patients with acute myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) study
    Sohail Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester, United Kingdom
    J Am Coll Cardiol 49:1525-32. 2007
    ..This study sought to assess the prognostic impact of midregional pro-adrenomedullin (MR-proADM) after an acute myocardial infarction (AMI)...
  8. pmc Myeloperoxidase aids prognostication together with N-terminal pro-B-type natriuretic peptide in high-risk patients with acute ST elevation myocardial infarction
    Sohail Q Khan
    Department of Cardiovascular Medicine, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester, UK
    Heart 93:826-31. 2007
    ..One such inflammatory marker is myeloperoxidase (MPO). Its role as a predictor of death or MI in patients with ST segment elevation myocardial infarction (STEMI) is unclear...
  9. ncbi Myotrophin is a more powerful predictor of major adverse cardiac events following acute coronary syndrome than N-terminal pro-B-type natriuretic peptide
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Clin Sci (Lond) 112:251-6. 2007
    ..63; P=0.006). In conclusion, after an ACS, levels of myotrophin are more informative at predicting MACE than NTproBNP and may be useful to risk stratify patients...
  10. ncbi C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptide (LAMP) study
    Sohail Q Khan
    University of Leicester, Department of Cardiovascular Sciences, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Circulation 115:2103-10. 2007
    ..We compared the prognostic value of copeptin and an established marker, N-terminal pro-B-type natriuretic peptide (NTproBNP), after acute myocardial infarction...
  11. doi Matrix metalloproteinase-2 predicts mortality in patients with acute coronary syndrome
    Onkar S Dhillon
    Department of Cardiovascular Sciences, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Clin Sci (Lond) 118:249-57. 2010
    ....
  12. doi Prognostic value of mid-regional pro-adrenomedullin levels taken on admission and discharge in non-ST-elevation myocardial infarction: the LAMP (Leicester Acute Myocardial Infarction Peptide) II study
    Onkar S Dhillon
    Department of Cardiovascular Sciences, University of Leicester, Leicester Royal Infirmary, Leicester, United Kingdom
    J Am Coll Cardiol 56:125-33. 2010
    ..N-terminal pro-B-type natriuretic peptide and GRACE (Global Registry of Acute Coronary Events) score were used as comparators...
  13. doi Usefulness of plasma tissue inhibitors of metalloproteinases as markers of prognosis after acute myocardial infarction
    Dominic Kelly
    Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    Am J Cardiol 106:477-82. 2010
    ..001 for all comparisons, log-rank test). In conclusion, higher plasma TIMP-1, -2, and -4 after AMI are associated with MACEs and provide additional prognostic information to that obtained from GRACE clinical risk scores alone...
  14. doi C-terminal provasopressin (copeptin) is associated with left ventricular dysfunction, remodeling, and clinical heart failure in survivors of myocardial infarction
    Dominic Kelly
    Department of Cardiovascular Sciences, University of Leicester, UK
    J Card Fail 14:739-45. 2008
    ..The aim of this study was to describe the association between Copeptin with LV dysfunction, volumes, and remodeling and clinical heart failure post-AMI...
  15. doi Procalcitonin as a prognostic marker in patients with acute myocardial infarction
    Dominic Kelly
    Department of Cardiovascular Sciences, University of Leicester, Leicester Royal Infirmary, Leicester, UK
    Biomarkers 15:325-31. 2010
    ..Procalcitonin is involved in the inflammatory response and is associated with adverse prognosis in certain conditions...
  16. ncbi Cardiotrophin-1 predicts death or heart failure following acute myocardial infarction
    Sohail Q Khan
    Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom
    J Card Fail 12:635-40. 2006
    ..However, its role as a predictor of death or heart failure is unclear. We sought to investigate this and compared it with N terminal pro-B-type natriuretic peptide (NT-proBNP), a marker of death or heart failure...
  17. pmc Proteinase 3 and prognosis of patients with acute myocardial infarction
    Leong L Ng
    Department of Cardiovascular Sciences, University of Leicester, Leicester LE2 7LX, UK
    Clin Sci (Lond) 120:231-8. 2011
    ..PR3 may represent a clinically useful marker of prognosis after an AMI as part of a multimarker strategy...
  18. doi Pre-discharge risk stratification in unselected STEMI: Is there a role for ST2 or its natural ligand IL-33 when compared with contemporary risk markers?
    Onkar S Dhillon
    Department of Cardiovascular Sciences, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester LE3 9QP, UK Electronic address
    Int J Cardiol 167:2182-8. 2013
    ..We assess the incremental value they offer over GRACE score and NT-proBNP. Secondary endpoints were heart failure readmission and re-infarction...
  19. pmc Plasma tissue inhibitor of metalloproteinase-1 and matrix metalloproteinase-9: novel indicators of left ventricular remodelling and prognosis after acute myocardial infarction
    Dominic Kelly
    Department of Cardiovascular Sciences, University of Leicester, Clinical Sciences Building, Leicester Royal Infirmary, Leicester LE2 7LX, UK
    Eur Heart J 29:2116-24. 2008
    ..We assessed the relationships with LV structure and function and outcome, of tissue inhibitors of metalloproteinase-1 (TIMP-1) and MMP-9, and compared with N-terminal pro-B-type natriuretic peptide (NTproBNP)...