Keith M Kerr

Summary

Affiliation: University of Aberdeen
Country: UK

Publications

  1. ncbi request reprint Expression of Fhit, cell adhesion molecules and matrix metalloproteinases in atypical adenomatous hyperplasia and pulmonary adenocarcinoma
    Keith M Kerr
    Department of Pathology, Aberdeen University Medical School, Aberdeen, UK
    J Pathol 203:638-44. 2004
  2. pmc The role of DNA methylation in the development and progression of lung adenocarcinoma
    Keith M Kerr
    Department of Pathology, Aberdeen Royal Infirmary, Link Building, Foresterhill, Aberdeen, AB25 2ZN, UK
    Dis Markers 23:5-30. 2007
  3. ncbi request reprint Classification of lung cancer: proposals for change?
    Keith M Kerr
    Department of Pathology, Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, UK
    Arch Pathol Lab Med 136:1190-3. 2012
  4. doi request reprint Personalized medicine for lung cancer: new challenges for pathology
    Keith M Kerr
    Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    Histopathology 60:531-46. 2012
  5. pmc Pulmonary preinvasive neoplasia
    K M Kerr
    Department of Pathology, Aberdeen Royal Infirmary and Aberdeen University Medical School, Foresterhill, Aberdeen AB25 2ZD, UK
    J Clin Pathol 54:257-71. 2001
  6. doi request reprint Pulmonary adenocarcinomas: classification and reporting
    Keith M Kerr
    Department of Pathology, Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    Histopathology 54:12-27. 2009
  7. doi request reprint Subtyping of undifferentiated non-small cell carcinomas in bronchial biopsy specimens
    Peh Sun Loo
    Department of Pathology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, UK
    J Thorac Oncol 5:442-7. 2010
  8. doi request reprint Thymidylate synthase expression and outcome of patients receiving pemetrexed for advanced nonsquamous non-small-cell lung cancer in a prospective blinded assessment phase II clinical trial
    Marianne C Nicolson
    Thoracic Oncology, Aberdeen Royal Infirmary, University of Aberdeen, Aberdeen, United Kingdom
    J Thorac Oncol 8:930-9. 2013
  9. ncbi request reprint Gene expression profiling in non-small cell lung cancer: from molecular mechanisms to clinical application
    Russell D Petty
    Department of Oncology, Aberdeen and Oncology Research Group, Department of Medicine and Therapeutics, University of Aberdeen, Aberdeen, United Kingdom
    Clin Cancer Res 10:3237-48. 2004
  10. doi request reprint In compressed lung tissue microscopic sections of adenocarcinoma in situ may mimic papillary adenocarcinoma
    Erik Thunnissen
    From the Departments of Pathology Drs Thunnissen and Beliën, Radiology Dr Lely, and Surgery Dr Hartemink, VU University Medical Center, Amsterdam, the Netherlands the Department of Pathology, Aberdeen Royal Infirmary, Aberdeen University Medical School, Aberdeen, Scotland Dr Kerr the Department of Pathology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea Dr Chung the Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania Dr Flieder the Department of Pathology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan Dr Noguchi the Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan Dr Yatabe the Department of Pathology, University Health Network Princess Margaret Hospital and University of Toronto, Toronto, Ontario, Canada Drs Hwang and Tsao and the Department of Pathology, Symbiant Medical Center Alkmaar, Alkmaar, the Netherlands Dr Meijer Jorna
    Arch Pathol Lab Med 137:1792-7. 2013

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Expression of Fhit, cell adhesion molecules and matrix metalloproteinases in atypical adenomatous hyperplasia and pulmonary adenocarcinoma
    Keith M Kerr
    Department of Pathology, Aberdeen University Medical School, Aberdeen, UK
    J Pathol 203:638-44. 2004
    ..Loss of MMP-2 and TIMP-2 in stromally invasive tumour may reflect a particular role for MMP-2 at the BAC stage, with later down-regulation of this particular enzyme...
  2. pmc The role of DNA methylation in the development and progression of lung adenocarcinoma
    Keith M Kerr
    Department of Pathology, Aberdeen Royal Infirmary, Link Building, Foresterhill, Aberdeen, AB25 2ZN, UK
    Dis Markers 23:5-30. 2007
    ....
  3. ncbi request reprint Classification of lung cancer: proposals for change?
    Keith M Kerr
    Department of Pathology, Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, UK
    Arch Pathol Lab Med 136:1190-3. 2012
    ..The huge increase in data on the molecular biology of lung cancer has improved our understanding of these diseases, has driven improved therapy for some patients, and must be reflected in the way lung cancer is classified...
  4. doi request reprint Personalized medicine for lung cancer: new challenges for pathology
    Keith M Kerr
    Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    Histopathology 60:531-46. 2012
    ..This extended diagnostic requirement from increasingly limited material provided by minimally invasive biopsy techniques poses major challenges for pathology...
  5. pmc Pulmonary preinvasive neoplasia
    K M Kerr
    Department of Pathology, Aberdeen Royal Infirmary and Aberdeen University Medical School, Foresterhill, Aberdeen AB25 2ZD, UK
    J Clin Pathol 54:257-71. 2001
    ....
  6. doi request reprint Pulmonary adenocarcinomas: classification and reporting
    Keith M Kerr
    Department of Pathology, Aberdeen University Medical School, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    Histopathology 54:12-27. 2009
    ..The emerging clinical and prognostic relevance of a number of histological features in these complex tumours strengthens the argument in favour of including quantitative detail of pattern sub-types in reports on resected tumours...
  7. doi request reprint Subtyping of undifferentiated non-small cell carcinomas in bronchial biopsy specimens
    Peh Sun Loo
    Department of Pathology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, Scotland, UK
    J Thorac Oncol 5:442-7. 2010
    ..Histochemical staining for mucin and immunohistochemical (IHC) identification of NSCLC subtype-associated markers could help predict the final subtype of resected NSCLCs diagnosed as NSCLC-NOS on preoperative bronchial biopsy samples...
  8. doi request reprint Thymidylate synthase expression and outcome of patients receiving pemetrexed for advanced nonsquamous non-small-cell lung cancer in a prospective blinded assessment phase II clinical trial
    Marianne C Nicolson
    Thoracic Oncology, Aberdeen Royal Infirmary, University of Aberdeen, Aberdeen, United Kingdom
    J Thorac Oncol 8:930-9. 2013
    ..This phase II study explored this association prospectively at the protein and mRNA-expression level...
  9. ncbi request reprint Gene expression profiling in non-small cell lung cancer: from molecular mechanisms to clinical application
    Russell D Petty
    Department of Oncology, Aberdeen and Oncology Research Group, Department of Medicine and Therapeutics, University of Aberdeen, Aberdeen, United Kingdom
    Clin Cancer Res 10:3237-48. 2004
    ..Taken together, these advances hold the promise of an improved understanding of the molecular biology of NSCLC and its treatment, which in turn will lead to improved outcomes for this deadly disease...
  10. doi request reprint In compressed lung tissue microscopic sections of adenocarcinoma in situ may mimic papillary adenocarcinoma
    Erik Thunnissen
    From the Departments of Pathology Drs Thunnissen and Beliën, Radiology Dr Lely, and Surgery Dr Hartemink, VU University Medical Center, Amsterdam, the Netherlands the Department of Pathology, Aberdeen Royal Infirmary, Aberdeen University Medical School, Aberdeen, Scotland Dr Kerr the Department of Pathology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea Dr Chung the Department of Pathology, Fox Chase Cancer Center, Philadelphia, Pennsylvania Dr Flieder the Department of Pathology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Japan Dr Noguchi the Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan Dr Yatabe the Department of Pathology, University Health Network Princess Margaret Hospital and University of Toronto, Toronto, Ontario, Canada Drs Hwang and Tsao and the Department of Pathology, Symbiant Medical Center Alkmaar, Alkmaar, the Netherlands Dr Meijer Jorna
    Arch Pathol Lab Med 137:1792-7. 2013
    ..Surgical removal and pathologic handling of lung tissue has a compressive effect upon its architecture. The effect of surgical atelectasis on morphology has not been examined in depth, especially with respect to lung adenocarcinomas...
  11. doi request reprint Quantitative analysis of tumor in bronchial biopsy specimens
    Caroline L Coghlin
    Department of Pathology, Aberdeen Royal Infirmary and Aberdeen University Medical School, Aberdeen, United Kingdom
    J Thorac Oncol 5:448-52. 2010
    ..We analyzed a series of 100 bronchial biopsy specimens in lung cancer patients to assess the frequency and quantity of tumor present in biopsy samples...
  12. ncbi request reprint Serpin b3 is associated with poor survival after chemotherapy and is a potential novel predictive biomarker in advanced non-small-cell lung cancer
    Gordon Urquhart
    School of Medicine and Dentistry, University of Aberdeen, Foresterhill Healthcare Campus, Foresterhill, Aberdeen, Scotland, United Kingdom and Departments of Oncology and Pathology Aberdeen Royal Infirmary, Foresterhill Healthcare Campus, Foresterhill, Aberdeen, Scotland, United Kingdom
    J Thorac Oncol 8:1502-9. 2013
    ..This independent prospective study was designed to confirm the predictive utility of SB3...
  13. ncbi request reprint Spontaneous dissection of an anomalous systemic artery in the lung during pregnancy: a rare cause of hemoptysis
    Shafaque Shaikh
    Department of Cardiothoracic Surgery, Aberdeen Royal Infirmary, Aberdeen, United Kingdom
    Ann Thorac Surg 82:725-6. 2006
    ..This article aims to discuss the clinical presentation, diagnostic curiosity, management using a minimally invasive technique (video-assisted thoracoscopic lobectomy), and finally the histopathologic findings...
  14. ncbi request reprint Evaluation of NQO1 gene expression and variant allele in human NSCLC tumors and matched normal lung tissue
    Jill M Kolesar
    School of Pharmacy, University of Wisconsin Madison, 777 Highland Avenue, Madison, WI 53706 1515, USA
    Int J Oncol 21:1119-24. 2002
    ..007), suggesting NQO1 may be important in chemosensitivity as well as the pathogenesis of lung cancer and NQO1 genotyping may be a useful component of pharmacogenetic strategies for the treatment of NSCLC...
  15. ncbi request reprint Tumor transcriptome reveals the predictive and prognostic impact of lysosomal protease inhibitors in non-small-cell lung cancer
    Russell D Petty
    Oncology Research Group, Department of Medicine and Therapeutics, Institute of Medical Sciences, School of Medicine, University of Aberdeen, Aberdeen, nited Kingdom
    J Clin Oncol 24:1729-44. 2006
    ..Insight into clinical response to platinum-based chemotherapy (PBC) in non-small-cell lung cancer (NSCLC)...
  16. ncbi request reprint Changing trends in incidence of lung cancer by histologic type in Scotland
    Elaine F Harkness
    ARC Epidemiology Unit, Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
    Int J Cancer 102:179-83. 2002
    ..Changes in histologic types are unlikely to be solely due to diagnostic advances. Rates of adenocarcinoma have increased steadily over time, and this may be due to changes in cigarette design during the 1950s...