Lindsey Kent

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Recent advances in the genetics of attention deficit hyperactivity disorder
    Lindsey Kent
    Developmental Psychiatry Section, University of Cambridge, Douglas House, Cambridge CB2 2AH, UK
    Curr Psychiatry Rep 6:143-8. 2004
  2. ncbi request reprint Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD
    L Kent
    Developmental Psychiatry, University of Cambridge, Cambridge, UK
    Mol Psychiatry 10:939-43. 2005
  3. pmc Methylphenidate improves response inhibition but not reflection-impulsivity in children with attention deficit hyperactivity disorder (ADHD)
    Elise E DeVito
    Department of Psychiatry, University of Cambridge, P O Box 189, Addenbrooke s Hospital, Cambridge CB22QQ, UK
    Psychopharmacology (Berl) 202:531-9. 2009
  4. pmc The effects of methylphenidate on decision making in attention-deficit/hyperactivity disorder
    Elise E DeVito
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Biol Psychiatry 64:636-9. 2008
  5. ncbi request reprint Variations in the human cannabinoid receptor (CNR1) gene modulate striatal responses to happy faces
    Bhismadev Chakrabarti
    Autism Research Centre, Douglas House, 18 B, Trumpington Road, Cambridge CB2 2AH, UK
    Eur J Neurosci 23:1944-8. 2006
  6. ncbi request reprint No association between TPH2 gene polymorphisms and ADHD in a UK sample
    Karen Sheehan
    Neuropsychiatric Genetics, Trinity Centre for Health Sciences, St James Hospital, Dublin 8, Ireland
    Neurosci Lett 412:105-7. 2007
  7. ncbi request reprint Insights into the control of attentional set in ADHD using the attentional blink paradigm
    Deanna J Mason
    School of Psychology, University of Exeter, UK
    J Child Psychol Psychiatry 46:1345-53. 2005
  8. pmc Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes
    Naomi Lowe
    Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Hum Genet 74:348-56. 2004
  9. ncbi request reprint The mitochondrial DNA A3243A>G mutation must be an infrequent cause of Asperger syndrome
    Lindsey Kent
    J Pediatr 149:280-1. 2006
  10. ncbi request reprint An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD
    Zahoor Syed
    Addenbrookes Hospital, Cambridge, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 144:375-8. 2007

Detail Information

Publications13

  1. ncbi request reprint Recent advances in the genetics of attention deficit hyperactivity disorder
    Lindsey Kent
    Developmental Psychiatry Section, University of Cambridge, Douglas House, Cambridge CB2 2AH, UK
    Curr Psychiatry Rep 6:143-8. 2004
    ..Current challenges in this field are to identify the actual functional variant(s) in these genes conferring susceptibility and other genetic and environmental risk factors for ADHD...
  2. ncbi request reprint Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD
    L Kent
    Developmental Psychiatry, University of Cambridge, Cambridge, UK
    Mol Psychiatry 10:939-43. 2005
    ..00; P=1.00). Our findings support the hypothesis that BDNF is involved in the pathogenesis of ADHD. The transmission difference between parents raises the possibility that an epigenetic process may be involved...
  3. pmc Methylphenidate improves response inhibition but not reflection-impulsivity in children with attention deficit hyperactivity disorder (ADHD)
    Elise E DeVito
    Department of Psychiatry, University of Cambridge, P O Box 189, Addenbrooke s Hospital, Cambridge CB22QQ, UK
    Psychopharmacology (Berl) 202:531-9. 2009
    ..However, impulsivity is a multi-factorial construct and the degree to which different forms of impulsivity contribute to impairments in ADHD or respond to pharmacological treatments remains unclear...
  4. pmc The effects of methylphenidate on decision making in attention-deficit/hyperactivity disorder
    Elise E DeVito
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Biol Psychiatry 64:636-9. 2008
    ..The objectives of the study were to assess the effects of stimulant medication on decision making in ADHD and compare performance on the Cambridge Gamble Task between boys with and without ADHD...
  5. ncbi request reprint Variations in the human cannabinoid receptor (CNR1) gene modulate striatal responses to happy faces
    Bhismadev Chakrabarti
    Autism Research Centre, Douglas House, 18 B, Trumpington Road, Cambridge CB2 2AH, UK
    Eur J Neurosci 23:1944-8. 2006
    ..This has implications for medical conditions involving hypo-responsivity to emotional and social stimuli, such as autism...
  6. ncbi request reprint No association between TPH2 gene polymorphisms and ADHD in a UK sample
    Karen Sheehan
    Neuropsychiatric Genetics, Trinity Centre for Health Sciences, St James Hospital, Dublin 8, Ireland
    Neurosci Lett 412:105-7. 2007
    ..A larger sample size will be required to clarify if TPH2 alleles are or are not associated with ADHD...
  7. ncbi request reprint Insights into the control of attentional set in ADHD using the attentional blink paradigm
    Deanna J Mason
    School of Psychology, University of Exeter, UK
    J Child Psychol Psychiatry 46:1345-53. 2005
    ..This study compared ADHD to control children on a temporal search task using Rapid Serial Visual Presentation (RSVP). In addition, the effects of irrelevant singleton distractors on search performance were examined...
  8. pmc Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes
    Naomi Lowe
    Department of Genetics, Trinity College, Dublin 2, Ireland
    Am J Hum Genet 74:348-56. 2004
    ..The joint analysis showed association with the DRD5 locus (P=.00005; odds ratio 1.24; 95% confidence interval 1.12-1.38). This association appears to be confined to the predominantly inattentive and combined clinical subtypes...
  9. ncbi request reprint The mitochondrial DNA A3243A>G mutation must be an infrequent cause of Asperger syndrome
    Lindsey Kent
    J Pediatr 149:280-1. 2006
  10. ncbi request reprint An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD
    Zahoor Syed
    Addenbrookes Hospital, Cambridge, United Kingdom
    Am J Med Genet B Neuropsychiatr Genet 144:375-8. 2007
    ..69, odds ratio (OR) = 1.65, P = 0.05). Although this SNP is located in the 5' pro-NGF sequence and not the mature NGF protein, it may affect intracellular processing and secretion of NGF...
  11. doi request reprint Beckwith Weidemann syndrome: a behavioral phenotype-genotype study
    Lindsey Kent
    Bute Medical School, University of St Andrews, St Andrews, Scotland, UK
    Am J Med Genet B Neuropsychiatr Genet 147:1295-7. 2008
    ..These findings suggest a potential role for the 11p15.5 imprinted gene cluster in ASD and indicate a need for further investigations of neurobehavioral phenotypes in BWS...
  12. ncbi request reprint Is there a relationship between attention deficit hyperactivity disorder and bipolar disorder?
    Lindsey Kent
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, UK
    J Affect Disord 73:211-21. 2003
    ..However, several fundamental methodological issues require rectification in future research in order to further elucidate the relationship between these disorders...
  13. ncbi request reprint Association study of a SNAP-25 microsatellite and attention deficit hyperactivity disorder
    Jonathan Mill
    Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, United Kingdom
    Am J Med Genet 114:269-71. 2002
    ..Within-family tests of linkage and association confirmed these findings. Further work is needed to ascertain the role of SNAP-25 in ADHD and assess the functional significance of this polymorphism...