Research Topics
Species | Stephen KennedySummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
MAVIDOS Maternal Vitamin D Osteoporosis Study: study protocol for a randomized controlled trial. The MAVIDOS Study GroupNicholas C Harvey
MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, UK
Trials 13:13. 2012..MAVIDOS is a randomised, double-blind, placebo-controlled trial (ISRCTN82927713, registered 2008 Apr 11), funded by Arthritis Research UK, MRC, Bupa Foundation and NIHR...- Effect of malaria on placental volume measured using three-dimensional ultrasound: a pilot studyMarcus J Rijken
Shoklo Malaria Research Unit, PO Box 46, Mae Sot, Tak 63110, Thailand
Malar J 11:5. 2012.... 
Randomized controlled trial assessing a traditional Chinese medicine remedy in the treatment of primary dysmenorrheaStephen Kennedy
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, Oxfordshire, United Kingdom
Fertil Steril 86:762-4. 2006..However, some efficacy parameters suggested possible superiority of the active treatment and so a larger study needs to be performed to determine whether this remedy has a role in the treatment of dysmenorrhea...- The Duarte (N314D) variant in the GALT gene has no effect on in vitro fertilization outcomeShigeki Yoshida
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom
Fertil Steril 85:502-4. 2006..Our data do not definitely exclude variants in the GALT gene as factors influencing outcome, but the lack of suggestive evidence makes it difficult to justify a larger, more definitive study... - Should a diagnosis of endometriosis be sought in all symptomatic women?Stephen Kennedy
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom
Fertil Steril 86:1312-3; discussion 1317. 2006..Such an approach might reduce the number of unnecessary laparoscopies without adversely affecting outcomes... - ESHRE guideline for the diagnosis and treatment of endometriosisStephen Kennedy
University of Oxford, UK
Hum Reprod 20:2698-704. 2005..The management of severe/deeply infiltrating endometriosis is complex and referral to a centre with the necessary expertise is strongly recommended. Patient self-help groups can provide invaluable counselling, support and advice... 
Evaluation of the American version of the 30-item Endometriosis Health Profile (EHP-30)Crispin Jenkinson
Health Services Research Unit, Department of Public Health and Harris Manchester College, University of Oxford, Old Road Campus, Headington, Oxford, OX3 7LF, UK
Qual Life Res 17:1147-52. 2008..In this study, we evaluated the response rate, data quality, score reliability and scaling assumptions of the 30-item Endometriosis Health Profile (EHP-30) in the USA...- Evaluating the responsiveness of the Endometriosis Health Profile Questionnaire: the EHP-30Georgina Jones
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, United Kingdom
Qual Life Res 13:705-13. 2004..To evaluate the sensitivity to change of the Endometriosis Health Profile-30 (EHP-30) questionnaire... - Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countriesKelechi E Nnoaham
Department of Public Health, University of Oxford, Oxford, UK
Fertil Steril 96:366-373.e8. 2011..To assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity... - The impact of endometriosis upon quality of life: a qualitative analysisGeorgina Jones
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, UK
J Psychosom Obstet Gynaecol 25:123-33. 2004..to explore and describe the impact of endometriosis upon quality of life... - Brain imaging reveals that engagement of descending inhibitory pain pathways in healthy women in a low endogenous estradiol state varies with testosteroneKaty Vincent
Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, Nuffield Division of Anaesthetics, University of Oxford, UK
Pain 154:515-24. 2013..Specifically, failure to engage descending inhibition at the level of the rostral ventromedial medulla may be responsible for the reduction in temperature required by COCP users with low circulating testosterone... - Dysmenorrhoea is associated with central changes in otherwise healthy womenKaty Vincent
Centre for Functional Magnetic Resonance Imaging of the Brain, Nuffield Department of Clinical Neurosciences, Nuffield Division Anaesthetics, University of Oxford, UK
Pain 152:1966-75. 2011..These findings indicate the potential importance of early and adequate treatment of dysmenorrhoea... - Measuring quality of life in women with endometriosis: tests of data quality, score reliability, response rate and scaling assumptions of the Endometriosis Health Profile QuestionnaireGeorgina Jones
School of Health and Related Research ScHARR, University of Sheffield, Sheffield, and Nuffield Department of Obstetrics and Gynaecology, Women s Centre, John Radcliffe Hospital, Oxford, UK
Hum Reprod 21:2686-93. 2006.... - Pain scoring in endometriosis: entry criteria and outcome measures for clinical trials. Report from the Art and Science of Endometriosis meetingKaty Vincent
Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headley Way, Oxford, United Kingdom
Fertil Steril 93:62-7. 2010..This report summarizes the recommendations from an international meeting for these criteria... - Volume segmentation and reconstruction from freehand three-dimensional ultrasound data with application to ovarian follicle measurementMark J Gooding
Wolfson Medical Vision Laboratory, Dept Engineering Science, University of Oxford, Parks Road, Oxford, UK
Ultrasound Med Biol 34:183-95. 2008..However, both the clinical measurement and the semi-automatic method appear to underestimate the true follicular volume... - Endometriosis: new genetic approaches and therapyDavid H Barlow
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, The Women s Center, John Radcliffe Hospital, Oxford OX3 9DU, UK
Annu Rev Med 56:345-56. 2005..This review describes the current status of these studies and explores the prospects for new therapies... - "People sometimes react funny if they're not told enough": women's views about the risks of diagnostic laparoscopyJane Moore
Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
Health Expect 5:302-9. 2002.... - Development of the Short Form Endometriosis Health Profile Questionnaire: the EHP-5Georgina Jones
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, United Kingdom
Qual Life Res 13:695-704. 2004..To develop and validate a short form version of the Endometriosis Health Profile-30 questionnaire which consists of a 30-item core questionnaire and a 23 item modular questionnaire... - Prioritizing IVF patients according to the number of existing children--a proposed refinement to the current guidelineBart Chwalisz
Nuffield Department of Obstetrics and Gynaecology and The Ethox Centre, Division of Public Health and Primary Care, University of Oxford, Oxford, UK
Hum Reprod 21:1110-2. 2006..Our approach treats like cases alike, and ranks different cases relative to each other in a manner that is equitable and charitable... - Description of a novel polymorphic gene encoding for arylamine N-acetyltransferase in the rhesus macaque (Macaca mulatta), a model animal for endometriosisGiannoulis Fakis
Nuffield Department of Obstetrics and Gynecology, John Radcliffe Hospital, University of Oxford, Oxford, UK
Pharmacogenet Genomics 17:181-8. 2007..To better understand the possible relationship between the NAT2 gene and endometriosis, we characterized its homologue in the rhesus macaque, an animal model for the disease... - Variants in EMX2 and PTEN do not contribute to risk of endometriosisSusan A Treloar
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Brisbane, Queensland 4029, Australia, and Nuffield Department of Obstetrics and Gynaecology, University of Oxford, UK
Mol Hum Reprod 13:587-94. 2007..It is unlikely that the EMX2 or PTEN gene variants investigated contribute to risk for initiation and/or development of endometriosis... - Allelic loss studies do not provide evidence for the "endometriosis-as-tumor" theoryAmanda H Prowse
Nuffield Department of Obstetrics and Gynaecology and Women's Centre, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
Fertil Steril 83:1134-43. 2005..RESULT(S): We identified LOH in only one lesion at one locus (D8S261). CONCLUSION(S): Our data do not support the hypothesis that ovarian endometriosis is a true neoplasm... - Development of a Web site for the genetic epidemiology of endometriosisKrina Zondervan
Wellcome Trust Centre for Human Genetics, Oxford, United Kingdom
Fertil Steril 78:777-81. 2002..Results of these studies and the wealth of gene and marker sequence information from the Human Genome Project could--when brought together--provide the researcher with new etiological avenues to explore... - Genetics of endometriosis: a review of the positional cloning approachesStephen Kennedy
Nuffield Department of Obstetrics Gynaecology, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom
Semin Reprod Med 21:111-8. 2003..The strategy should lead to the discovery of new drug targets, which will be a major advance given that treatment to date has focused upon crude manipulation of ovarian function... - The genetic epidemiology of spontaneous endometriosis in the rhesus monkeyKrina Zondervan
Wellcome Trust Centre for Human Genetics, University of Oxford, United Kingdom
Ann N Y Acad Sci 955:233-8; discussion 293-5, 396-406. 2002.... - N-acetyl transferase 2 polymorphism and advanced stages of endometriosis in South Indian womenK Arvind Babu
Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
Reprod Biomed Online 9:533-40. 2004.... - Differences in characteristics among 1,000 women with endometriosis based on extent of diseaseNinet Sinaii
Biostatistics and Clinical Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1871, USA
Fertil Steril 89:538-45. 2008..To determine the relationship between disease severity and patient characteristics in endometriosis... - The tumor necrosis factor-alpha promoter -1031C polymorphism is associated with decreased risk of endometriosis in a Japanese populationTasneem Asghar
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, 7 5 1 Kusunoki cho, Chuo Ku, Kobe, 650 0017, Japan
Hum Reprod 19:2509-14. 2004..In this study, we investigated the possible association between endometriosis and the TNF-alpha gene promoter polymorphisms -238G/A, -308G/A, -857C/T, -863C/A and -1031T/C in a Japanese population... - The vascular endothelial growth factor (VEGF) +405G>C 5'-untranslated region polymorphism and increased risk of endometriosis in South Indian women: a case control studyManjula Bhanoori
Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
Hum Reprod 20:1844-9. 2005..Vascular endothelial growth factor (VEGF), a major mediator of angiogenesis and vascular permeability, is known to play a key role in the pathophysiology of endometriosis... - The International Endogene Study: a collection of families for genetic research in endometriosisSusan Treloar
Cooperative Research Centre for Discovery of Genes for Common Human Diseases, Queensland Institute of Medical Research, Brisbane, Australia
Fertil Steril 78:679-85. 2002..The aim of the International Endogene Study is to discover genes that influence susceptibility to endometriosis... - The interleukin-6 -174G/C promoter polymorphism is not associated with endometriosis in South Indian womenManjula Bhanoori
Centre for Cellular and Molecular Biology, Hyderabad, India
J Soc Gynecol Investig 12:365-9. 2005..To investigate the association of the -174 G/C promoter polymorphism of the interleukin-6 (IL-6) gene with endometriosis in South Indian women... - The G2964A 3'-untranslated region polymorphism of the signal transducer and activator of transcription 6 gene is associated with endometriosis in South Indian womenManjula Bhanoori
Centre for Cellular and Molecular Biology, Hyderabad, Andhra Pradesh, India
Hum Reprod 22:1026-30. 2007..The aim of the study was to test whether the signal transducer and activator of transcription 6 (STAT6) gene influences the risk of developing endometriosis... - GSTM1, GSTT1 and CYP1A1 detoxification gene polymorphisms and their relationship with advanced stages of endometriosis in South Indian womenK Arvind Babu
Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India
Pharmacogenet Genomics 15:167-72. 2005..The present study was undertaken to investigate the frequency of the CYP1A1 (6235T>C) polymorphism and GSTM1, GSTT1 null mutations in a South Indian women's population with and without endometriosis... - Association study of endometriosis and intercellular adhesion molecule-1 (ICAM-1) gene polymorphisms in a Japanese populationMasako Yamashita
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
J Soc Gynecol Investig 12:267-71. 2005..In this study, we investigated the possible association between endometriosis and the G241R and K469E polymorphisms in the intercellular adhesion molecule-1 (ICAM-1) gene in a Japanese population... - The CYP17 MspA1 polymorphism is not associated with an increased risk of uterine leiomyomas in a Japanese populationTaro Tsujino
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
Gynecol Endocrinol 22:87-91. 2006..These findings suggest that CYP17 gene polymorphism is unlikely to be associated with an increased risk of uterine leiomyomas in a Japanese population... - Lack of association between endometriosis and the CYP17 MspA1 polymorphism in UK and Japanese populationsTasneem Asghar
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
Gynecol Endocrinol 20:59-63. 2005..2%] (cases) and 89/179 [49.7%] (controls) for A1A2; and 26/130 [20.0%] (cases) and 33/179 [18.4%] (controls) for A2A2. The CYP17 MspA1 polymorphism is probably not associated with endometriosis in either the UK or the Japanese population... - Polymorphisms in the estrogen receptor beta gene but not estrogen receptor alpha gene affect the risk of developing endometriosis in a Japanese populationZhuo Wang
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
Fertil Steril 81:1650-6. 2004..To determine whether polymorphisms in the estrogen receptor (ER) alpha and beta genes are associated with endometriosis in a Japanese population... - Matrix metalloproteinase-1 and -9 promoter polymorphisms and endometrial carcinoma risk in a Japanese populationMakoto Sugimoto
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
J Soc Gynecol Investig 13:523-9. 2006..The object of this study was to investigate whether the MMP-1 and MMP-9 gene promoter polymorphisms are associated with endometrial carcinomas in a Japanese population... - Vascular endothelial growth factor +936 C/T polymorphism is associated with an increased risk of endometriosis in a Japanese populationYoshiyuki Ikuhashi
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Chuo Ku, Kobe, Japan
Acta Obstet Gynecol Scand 86:1352-8. 2007..In this study, we investigated whether polymorphisms in the VEGF gene are associated with endometriosis in a Japanese population... - Medical justice for undocumented migrantsFrank Arnold
Lancet 371:201. 2008 - Lack of association between endometriosis and N-acetyl transferase 1 (NAT1) and 2 (NAT2) polymorphisms in a Japanese populationMasashi Deguchi
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
J Soc Gynecol Investig 12:208-13. 2005.... - Matrix metalloproteinase-1 and -9 promoter polymorphisms are not associated with an increased risk of uterine leiomyomas in a Japanese populationNaoya Takemura
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
J Soc Gynecol Investig 13:232-6. 2006..Hence, we investigated whether associations exist between leiomyomas and promoter polymorphisms in the MMP-1 and MMP-9 genes in a Japanese population... - Animal studies in endometriosis: a reviewLisa Story
University of Oxford Medical School, United Kingdom
ILAR J 45:132-8. 2004..This review explores the value of the experimental models that have been used to date... - No association of endometriosis with glutathione S-transferase M1 and T1 null mutations in a Japanese populationMayumi Morizane
Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe, Japan
J Soc Gynecol Investig 11:118-21. 2004..We investigated the frequency of glutathione S-transferase M1 and T1 (GSTM1 and GSTT1) null mutations in women with endometriosis in a Japanese population... - Women's health biobank in IndiaStephen Kennedy
Indian J Med Res 120:131-2. 2004