Sarah L Kempster

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Developmental control of the Nlrp6 inflammasome and a substrate, IL-18, in mammalian intestine
    Sarah L Kempster
    Dept of Obstetrics and Gynaecology, Univ of Cambridge, Box 223, Cambridge, CB2 0SW, United Kingdom
    Am J Physiol Gastrointest Liver Physiol 300:G253-63. 2011
  2. doi request reprint Paraoxonase-3, a putative circulating antioxidant, is systemically up-regulated in late gestation in the fetal rat, sheep, and human
    Gusztav Belteki
    Department of Obstetrics and Gynaecology, University of Cambridge, and Neonatal Intensive Care Unit, Addenbrooke s Hospital, Box 223, Cambridge CB2 0SW, United Kingdom
    J Clin Endocrinol Metab 95:3798-805. 2010
  3. doi request reprint Disruption of paraoxonase 3 impairs proliferation and antioxidant defenses in human A549 cells and causes embryonic lethality in mice
    Sarah L Kempster
    Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK
    Am J Physiol Endocrinol Metab 302:E103-7. 2012

Collaborators

Detail Information

Publications3

  1. pmc Developmental control of the Nlrp6 inflammasome and a substrate, IL-18, in mammalian intestine
    Sarah L Kempster
    Dept of Obstetrics and Gynaecology, Univ of Cambridge, Box 223, Cambridge, CB2 0SW, United Kingdom
    Am J Physiol Gastrointest Liver Physiol 300:G253-63. 2011
    ....
  2. doi request reprint Paraoxonase-3, a putative circulating antioxidant, is systemically up-regulated in late gestation in the fetal rat, sheep, and human
    Gusztav Belteki
    Department of Obstetrics and Gynaecology, University of Cambridge, and Neonatal Intensive Care Unit, Addenbrooke s Hospital, Box 223, Cambridge CB2 0SW, United Kingdom
    J Clin Endocrinol Metab 95:3798-805. 2010
    ..Although prematurity is associated with oxidative stress, no effective antioxidant therapy has yet been identified...
  3. doi request reprint Disruption of paraoxonase 3 impairs proliferation and antioxidant defenses in human A549 cells and causes embryonic lethality in mice
    Sarah L Kempster
    Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, UK
    Am J Physiol Endocrinol Metab 302:E103-7. 2012
    ..008) but not 2% oxygen. We conclude that the absence of Pon3 in mice resulted in increased rates of early fetal and neonatal death. Knockdown of PON3 in human cells reduced cell proliferation and total antioxidant capacity...