Denise Kelly

Summary

Affiliation: University of Aberdeen
Country: UK

Publications

  1. ncbi request reprint Importance of microbial colonization of the gut in early life to the development of immunity
    Denise Kelly
    Rowett Research Institute, Aberdeen, Scotland
    Mutat Res 622:58-69. 2007
  2. pmc Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity
    Imke E Mulder
    Gut Immunology Group, University of Aberdeen, Rowett Institute of Nutrition and Health, Aberdeen, United Kingdom
    PLoS ONE 6:e28279. 2011
  3. pmc Establishment of normal gut microbiota is compromised under excessive hygiene conditions
    Bettina Schmidt
    Gut Immunology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom
    PLoS ONE 6:e28284. 2011
  4. doi request reprint Microbes and microbial effector molecules in treatment of inflammatory disorders
    Denise Kelly
    Gut Immunology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK
    Immunol Rev 245:27-44. 2012
  5. doi request reprint Microbiome and immunological interactions
    Denise Kelly
    Rowett Institute of Nutrition and Health, University of Aberdeen, Foresterhill, Aberdeen, Scotland, UK
    Nutr Rev 70:S18-30. 2012
  6. pmc Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces
    Imke E Mulder
    Gut Immunology Group, University of Aberdeen, Rowett Institute of Nutrition and Health, Greenburn Road, Aberdeen AB21 9SB, UK
    BMC Biol 7:79. 2009
  7. ncbi request reprint Commensal gut bacteria: mechanisms of immune modulation
    Denise Kelly
    Gut Immunology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Trends Immunol 26:326-33. 2005
  8. pmc Tetracycline resistome of the organic pig gut
    Katarzyna A Kazimierczak
    Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 75:1717-22. 2009
  9. doi request reprint Inflammatory bowel disease, gut bacteria and probiotic therapy
    Caroline Reiff
    Department of Gut Immunology, Rowett Institute of Nutrition and Health, Greenburn Road, Bucksburn, AB21 9SB Aberdeen, UK
    Int J Med Microbiol 300:25-33. 2010
  10. ncbi request reprint Bacterial modulation of mucosal innate immunity
    Denise Kelly
    Gut Immunology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Mol Immunol 42:895-901. 2005

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Importance of microbial colonization of the gut in early life to the development of immunity
    Denise Kelly
    Rowett Research Institute, Aberdeen, Scotland
    Mutat Res 622:58-69. 2007
    ..However, much remains to be elucidated about how commensal bacteria influence the function of cells of both the innate and adaptive immune systems in health and disease...
  2. pmc Restricting microbial exposure in early life negates the immune benefits associated with gut colonization in environments of high microbial diversity
    Imke E Mulder
    Gut Immunology Group, University of Aberdeen, Rowett Institute of Nutrition and Health, Aberdeen, United Kingdom
    PLoS ONE 6:e28279. 2011
    ..Here, we address the impact of limiting microbial exposure after initial colonization on the development of adult gut immunity...
  3. pmc Establishment of normal gut microbiota is compromised under excessive hygiene conditions
    Bettina Schmidt
    Gut Immunology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, United Kingdom
    PLoS ONE 6:e28284. 2011
    ..Here, we sought to further investigate the impact of limiting microbial exposure during early life on the development of the pig gut microbiota...
  4. doi request reprint Microbes and microbial effector molecules in treatment of inflammatory disorders
    Denise Kelly
    Gut Immunology Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK
    Immunol Rev 245:27-44. 2012
    ..In addition, new information describing microbial genomes affords the opportunity to mine for functional genes that may lead to new generation drugs relevant to a range of inflammatory disease conditions...
  5. doi request reprint Microbiome and immunological interactions
    Denise Kelly
    Rowett Institute of Nutrition and Health, University of Aberdeen, Foresterhill, Aberdeen, Scotland, UK
    Nutr Rev 70:S18-30. 2012
    ..The detailed description of the human gut microbiota, integrated with evidence-based mechanisms of immune modulation, provides an exciting platform for the identification of next-generation probiotics and related pharmaceutical products...
  6. pmc Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces
    Imke E Mulder
    Gut Immunology Group, University of Aberdeen, Rowett Institute of Nutrition and Health, Greenburn Road, Aberdeen AB21 9SB, UK
    BMC Biol 7:79. 2009
    ..We addressed this important question using the pig as a model to evaluate the impact of early-life environment on microbe/host gut interactions during development...
  7. ncbi request reprint Commensal gut bacteria: mechanisms of immune modulation
    Denise Kelly
    Gut Immunology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Trends Immunol 26:326-33. 2005
    ..This crosstalk is likely to affect immunological tolerance and homeostasis within the gut and to explain some of the differential host responses to commensal and pathogenic bacteria...
  8. pmc Tetracycline resistome of the organic pig gut
    Katarzyna A Kazimierczak
    Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen AB21 9SB, United Kingdom
    Appl Environ Microbiol 75:1717-22. 2009
    ....
  9. doi request reprint Inflammatory bowel disease, gut bacteria and probiotic therapy
    Caroline Reiff
    Department of Gut Immunology, Rowett Institute of Nutrition and Health, Greenburn Road, Bucksburn, AB21 9SB Aberdeen, UK
    Int J Med Microbiol 300:25-33. 2010
    ..Bacterial-host events, including interactions with pattern recognition receptors (PRRs) expressed on epithelial cells and dendritic cells (DCs) and the resultant impact on immune responses at mucosal surfaces will be discussed...
  10. ncbi request reprint Bacterial modulation of mucosal innate immunity
    Denise Kelly
    Gut Immunology Group, Rowett Research Institute, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, UK
    Mol Immunol 42:895-901. 2005
    ..Hence, the possibility exists that bacterially derived effector molecules, with defined modes of action, may have clinical relevance and application...