Research Topics
| Matthew KeelingSummaryAffiliation: University of Warwick Country: UK Publications
Research Grants
| Collaborators |
Detail Information
Publications
Impact of regulatory perturbations to disease spread through cattle movements in Great BritainMatthew C Vernon
School of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry, United Kingdom
Prev Vet Med 105:110-7. 2012....
Optimal but unequitable prophylactic distribution of vaccineMatt J Keeling
Mathematics Institute and School of Life Sciences, University of Warwick, Coventry, United Kingdom
Epidemics 4:78-85. 2012..However, as greater realism is included, this extreme and arguably unethical policy, is replaced by an optimal strategy where vaccine supply is more evenly spatially distributed...
Topographic determinants of foot and mouth disease transmission in the UK 2001 epidemicNicholas J Savill
Statistical Laboratory, Centre for Mathematical Sciences, University of Cambridge, Wilberforce Road, Cambridge, CB3 0WB, UK
BMC Vet Res 2:3. 2006..This ideally requires a parallel record of spatial epidemic spread and a detailed map of susceptible host density along with relevant transport links and geographical features...
Contingency planning for a deliberate release of smallpox in Great Britain--the role of geographical scale and contact structureThomas House
Warwick Mathematics Institute and Department of Biological Sciences, University of Warwick, Coventry, UK
BMC Infect Dis 10:25. 2010..consider two key questions currently unanswered in the literature: firstly, what is the optimal spatial scale for intervention; and secondly, how sensitive are results to the modelling assumptions made about the pattern of human contacts?..
Targeting vaccination against novel infections: risk, age and spatial structure for pandemic influenza in Great BritainMatt J Keeling
Mathematics Institute and School of Life Sciences, University of Warwick, Coventry CV4 7AL, UK
J R Soc Interface 8:661-70. 2011..We discuss how all three of these priorities change as both the speed at which vaccination can be deployed and the start of the vaccination programme is varied...
Individual identity and movement networks for disease metapopulationsMatt J Keeling
Department of Biological Science and Mathematics Institute, University of Warwick, Coventry CV4 7AL, UK
Proc Natl Acad Sci U S A 107:8866-70. 2010....
Mathematical modelling of infectious diseasesM J Keeling
Biological Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK
Br Med Bull 92:33-42. 2009..Here, we illustrate these principles in relation to the current H1N1 epidemic...
Efficient methods for studying stochastic disease and population dynamicsM J Keeling
Department of Biological Sciences and Mathematics Institute, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK
Theor Popul Biol 75:133-41. 2009..The methods allow the possibility of extending exact Markov methods to real-world problems, providing techniques for efficient parameterisation and subsequent analysis...
On methods for studying stochastic disease dynamicsM J Keeling
Department of Biological Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK
J R Soc Interface 5:171-81. 2008....
Networks and epidemic modelsMatt J Keeling
Department of Biological Sciences and Mathematics, University of Warwick, Institute Gibbet Hill Road, Coventry CV4 7AL, UK
J R Soc Interface 2:295-307. 2005..Finally, we look to the future to suggest how the two fields of network theory and epidemiological modelling can deliver an improved understanding of disease dynamics and better public health through effective disease control...
Models of foot-and-mouth diseaseMatt J Keeling
Department of Biological Sciences and Mathematics Institute, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK
Proc Biol Sci 272:1195-202. 2005..Finally, the future of modelling is discussed, analysing the advances needed if models are to be successfully applied during any subsequent epidemics...
The implications of network structure for epidemic dynamicsMatt Keeling
Department of Biological Sciences and Mathematics Institute, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK
Theor Popul Biol 67:1-8. 2005..Here, the differences between mass-action and network-based models are investigated. This allows us to determine when mass-action models are a reliable tool, and suggest ways in which their behaviour should be refined...
Using conservation of pattern to estimate spatial parameters from a single snapshotMatt J Keeling
Mathematics Institute and Department of Biological Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, United Kingdom
Proc Natl Acad Sci U S A 101:9155-60. 2004..Although applicable to both ecological and epidemiological data, here we focus on disease data from computer simulations and real epidemics to show that this method produces reliable results that could be used in practical situations...
The invasion and coexistence of competing Wolbachia strainsM J Keeling
Mathematics Institute, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Heredity (Edinb) 91:382-8. 2003..A simplified model of such founder control suggests that it is fragmentation of (or barriers within) the habitat rather than space itself that leads to persistence...
Modelling vaccination strategies against foot-and-mouth diseaseM J Keeling
Department of Biological Science and Mathematics Institute, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK
Nature 421:136-42. 2003..These analyses have broader implications for the control of human and livestock infectious diseases in heterogeneous spatial landscapes...
Herd size and bovine tuberculosis persistence in cattle farms in Great BritainEllen Brooks-Pollock
Department of Biological Sciences and Mathematics Institute, University of Warwick, Coventry CV4 7AL, UK
Prev Vet Med 92:360-5. 2009....
Effect of data quality on estimates of farm infectiousness trends in the UK 2001 foot-and-mouth disease epidemicNicholas J Savill
Centre for Infectious Diseases, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh EH9 3JT, UK
J R Soc Interface 4:235-41. 2007..Here, we show that such data degradation prevents successful determination of trends in farm infectiousness...
Research Grants
- Evolution of Disease: Current patterns and future trendsMatthew Keeling; Fiscal Year: 2006..The types of trade-offs and constraints seen in the experimental systems can then be used to formulated more biologically mechanistic and more accurate computer models of disease evolution in higher organisms. ..
