Research Topics
| Annette Karmiloff-SmithSummaryAffiliation: University of London Country: UK Publications
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Detail Information
Publications
What can developmental disorders tell us about the neurocomputational constraints that shape development? The case of Williams syndromeAnnette Karmiloff-Smith
Neurocognitive Development Unit, Institute of Child Health, London, United Kingdom
Dev Psychopathol 15:969-90. 2003....- Williams syndromeAnnette Karmiloff-Smith
Centre for Brain and Cognitive Development, School of Psychology, Birkbeck, University of London, 32 Torrington Square, London WC1E 7HX, UK
Curr Biol 17:R1035-6. 2007 
Genetic and environmental vulnerabilities in children with neurodevelopmental disordersAnnette Karmiloff-Smith
Department of Psychological Sciences, Birkbeck Centre for Brain and Cognitive Development, London WC1N 7HX, United Kingdom
Proc Natl Acad Sci U S A 109:17261-5. 2012....
Challenging the use of adult neuropsychological models for explaining neurodevelopmental disorders: Developed versus developing brainsAnnette Karmiloff-Smith
a Centre for Brain and Cognitive Development, Birkbeck, University of London, London, UK
Q J Exp Psychol (Hove) 66:1-14. 2013....- Perspectives on the dynamic development of cognitive capacities: insights from Williams syndromeAnnette Karmiloff-Smith
Birkbeck Centre for Brain and Cognitive Development, University of London, London, UK
Curr Opin Neurol 25:106-11. 2012.... - Neuroimaging of the developing brain: taking "developing" seriouslyAnnette Karmiloff-Smith
Birkbeck Centre for Brain and Cognitive Development, University of London, London, United Kingdom
Hum Brain Mapp 31:934-41. 2010..Thus, a distinction needs to be drawn between child neuroimaging and developmental neuroimaging, the latter approach being relevant not just to children, but to adults and the ageing brain... - Nativism versus neuroconstructivism: rethinking the study of developmental disordersAnnette Karmiloff-Smith
Birkbeck College, University of London, UK
Dev Psychol 45:56-63. 2009..e., the emergent property over developmental time of dynamic, multidirectional interactions between genes, brain, cognition, behavior, and environment) with domain-specific outcomes impossible without the process of development... - Atypical epigenesisAnnette Karmiloff-Smith
Developmental Neurocognition Lab, Birkbeck, University of London, London, UK
Dev Sci 10:84-8. 2007..Atypical epigenesis may often involve a lack of specialization and localization of brain function over developmental time, even in cases of behavioural proficiency... - Comprehension of metaphor and metonymy in children with Williams syndromeDagmara Annaz
School of Psychology, Birkbeck, University of London, London, UK
Int J Lang Commun Disord 44:962-78. 2009..Few studies have investigated metaphor comprehension in Williams syndrome and none has investigated metonymy... - Developing spatial frequency biases for face recognition in autism and Williams syndromeHayley C Leonard
Centre for Brain and Cognitive Development, School of Psychological Sciences, Birkbeck, University of London, Malet Street, London WC1E 7HX, UK
J Autism Dev Disord 41:968-73. 2011..These data demonstrate that typical outcomes can be achieved through atypical developmental processes, and confirm the importance of cross-syndrome studies in the investigation of developmental disorders... - Using developmental trajectories to understand developmental disordersMichael S C Thomas
Developmental Neurocognition Laboratoy, School of Psychology, Birkbeck College, University of London, London, UK
J Speech Lang Hear Res 52:336-58. 2009..In this article, the authors present a tutorial on the use of developmental trajectories for studying language and cognitive impairments in developmental disorders and compare this method with the use of matching... - ERP abnormalities of illusory contour perception in Williams syndromeSarah J Grice
Centre for Brain and Cognitive Development, School of Psychology, Birkbeck College, University of London, Malet Street, London WC1E 7HX
Neuroreport 14:1773-7. 2003..We conclude that, contrary to earlier claims, there is atypical neural processing during low-level visual perception in Williams syndrome... - The development of metaphorical language comprehension in typical development and in Williams syndromeMichael S C Thomas
Developmental Neurocognition Lab, School of Psychology, Birkbeck College, University of London, London WC1E 7HX, UK
J Exp Child Psychol 106:99-114. 2010..Results indicated that individuals with Williams syndrome may access different, less abstract knowledge in figurative language comparisons despite the relatively strong verbal abilities found in this disorder... - Exploring the Williams syndrome face-processing debate: the importance of building developmental trajectoriesAnnette Karmiloff-Smith
Neurocognitive Development Unit, Institute of Child Health, London, UK
J Child Psychol Psychiatry 45:1258-74. 2004..Measurement of evoked brain potentials also point to atypical processes. However, two recent studies have claimed that people with WS process faces exactly like normal controls... - The development of spatial frequency biases in face recognitionHayley C Leonard
Centre for Brain and Cognitive Development, School of Psychology, Birkbeck, University of London, UK
J Exp Child Psychol 106:193-207. 2010..This suggests that specialization toward the mid-band for upright face recognition develops gradually during childhood and may relate to an advanced level of face expertise... - Typical and atypical development of visual estimation abilitiesDaniel Ansari
Neurocognitive Development Unit, Institute of Child Health, London, UK
Cortex 43:758-68. 2007.... - A cross-syndrome study of the development of holistic face recognition in children with autism, Down syndrome, and Williams syndromeDagmara Annaz
Developmental Neurocognition Lab, School of Psychology, Birkbeck College, University of London, London, UK
J Exp Child Psychol 102:456-86. 2009..We discuss the implications for theories of face recognition in both atypical and typical development, including the idea that part-whole and rotation manipulations may tap different aspects of holistic and/or configural processing... - Are developmental disorders like cases of adult brain damage? Implications from connectionist modellingMichael Thomas
Neurocognitive Development Unit, Institute of Child Health and School of Psychology, Birkbeck College, University of London, London WC1E 7HX, United Kingdom
Behav Brain Sci 25:727-50; discussion 750-87. 2002.... - When modularization fails to occur: a developmental perspectiveDean D'Souza
Birkbeck Centre for Brain and Cognitive Development, University of London, London, UK
Cogn Neuropsychol 28:276-87. 2011..In other words, in neurodevelopmental disorders the gradual process of relative modularization may fail to occur... - Mechanisms of developmental regression in autism and the broader phenotype: a neural network modeling approachMichael S C Thomas
Developmental Neurocognition Lab, Centre for Brain and Cognitive Development, Department of Psychological Sciences, Birkbeck, University of London, Malet Street, London WC1E 7HX, United Kingdom
Psychol Rev 118:637-54. 2011..1999). We make a novel prediction that the earliest developmental symptoms in the emergence of autism should be sensory and motor rather than social and review empirical data offering preliminary support for this prediction... - In-depth analysis of spatial cognition in Williams syndrome: A critical assessment of the role of the LIMK1 geneVictoria Gray
Psychology Department, Royal Holloway, University of London, UK
Neuropsychologia 44:679-85. 2006..We conclude that a deeper assessment of WS at the genetic level is required before the contribution of specific genes to phenotypic outcomes can be fully understood... - Love is... an abstract word: the influence of lexical semantics on verbal short-term memory in Williams syndromeEmma Laing
Institute of Child Health, London, UK
Cortex 41:169-79. 2005..The results demonstrate that, despite claims to the contrary, children and adults with WS are able to access and make use of lexical semantics in a verbal short-term memory task in a manner comparable to typically developing individuals... - Modeling language acquisition in atypical phenotypesMichael S C Thomas
Institute of Child Health, Neurocognitive Development Unit, London, England
Psychol Rev 110:647-82. 2003.... - The dynamics of ontogeny: a neuroconstructivist perspective on genes, brains, cognition and behaviorTessa M Dekker
Birkbeck Centre for Brain and Cognitive Development, University of London, London, UK
Prog Brain Res 189:23-33. 2011..Finally, we discuss future contributions of the neuroconstructivist approach to developmental research in particular, and cognitive neuroscience in general... - Social cognition in williams syndrome: genotype/phenotype insights from partial deletion patientsAnnette Karmiloff-Smith
Birkbeck Centre for Brain and Cognitive Development, University of London London, UK
Front Psychol 3:168. 2012..We discuss the implications of these findings for genotype/phenotype relations, as well as the advantages and limitations of animal models and of case study approaches... - Definitions versus categorization: assessing the development of lexico-semantic knowledge in Williams syndromeHarry R M Purser
Department of Psychology and Human Development, Institute of Education, University of London, London, UK
Int J Lang Commun Disord 46:361-73. 2011..Williams syndrome (WS) is associated with relatively strong language abilities despite mild to moderate intellectual disability, particularly when language is indexed by vocabulary... - Double dissociations in developmental disorders? Theoretically misconceived, empirically dubiousAnnette Karmiloff-Smith
Neurocognitive Development Unit, Institute of Child Health, London, UK
Cortex 39:161-3. 2003 - Neuroimaging of typical and atypical development: a perspective from multiple levels of analysisMark H Johnson
Centre for Brain and Cognitive Development, School of Psychology, Birkbeck College, University of London, UK
Dev Psychopathol 14:521-36. 2002.... - Discriminating power of localized three-dimensional facial morphologyPeter Hammond
Eastman Dental Institute, University College London, London, WC1X 8LD, United Kingdom
Am J Hum Genet 77:999-1010. 2005.... - Early categorization abilities in young children with Williams syndromeThierry Nazzi
Neurocognitive Development Unit, Institute of Child Health, London, UK
Neuroreport 13:1259-62. 2002..The present study hence supports the claim that vocabulary acquisition in Williams syndrome develops atypically... - Discovering structure in auditory input: evidence from Williams syndromeMayada Elsabbagh
Centre for Brain and Cognitive Development, Birkbeck, University of London, London
Am J Intellect Dev Disabil 115:128-39. 2010..Unlike controls who demonstrated greater proficiency when contour cues were available, adults with Williams syndrome showed no such advantage... - Characterisation of sleep problems in children with Williams syndromeDagmara Annaz
School of Health and Social Science, Middlesex University, London, UK
Res Dev Disabil 32:164-9. 2011..Furthermore the negative impact of sleep disturbances on daytime behaviour and learning should be measured before diagnoses of behaviourally defined disorders are considered... - Attention across modalities as a longitudinal predictor of early outcomes: the case of fragile X syndromeGaia Scerif
Attention, Brain and Cognitive Development Group, Department of Experimental Psychology, University of Oxford, Oxford, UK
J Child Psychol Psychiatry 53:641-50. 2012..FXS therefore represents an ideal model disorder to study prospectively the impact of early attention deficits on behaviour... - The dawn of cognitive genetics? Crucial developmental caveatsGaia Scerif
School of Psychology, University of Nottingham, Nottingham, UK
Trends Cogn Sci 9:126-35. 2005..Most importantly, interdisciplinary efforts to integrate human genetics and cognition will need to operationalize the mechanisms driving both typical and atypical developmental processes over time... - The missing developmental dimension in the network perspectiveSam Wass
Centre for Brain and Cognitive Development, Birkbeck College, University of London, London WC1E 7HX, United Kingdom
Behav Brain Sci 33:175-6. 2010..We discuss principles such as fan in, fan out, bottlenecks, and common pathways, and argue that modelling these developmental aspects can be vital, particularly in deriving properly targeted treatments... - A study of relative clauses in Williams syndromeJulia Grant
Neurocognitive Development Unit, Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
J Child Lang 29:403-16. 2002.... - Comprehension of spatial language terms in Williams syndrome: evidence for an interaction between domains of strength and weaknessCaroline E Phillips
Centre for the Study of Memory and Learning, Department of Experimental Psychology, University of Bristol, UK
Cortex 40:85-101. 2004..They also shed light on the ways in which spatial cognition may interact with language comprehension more generally... - Tracing syndrome-specific trajectories of attention across the lifespanKim Cornish
Neuroscience Laboratory for Research and Education in Children with Developmental Disorders, McGill University, Montreal, Canada
Cortex 43:672-85. 2007.... - Dethroning the myth: cognitive dissociations and innate modularity in Williams syndromeAnnette Karmiloff-Smith
ICH Neurocognitive Development Unit, London, England
Dev Neuropsychol 23:227-42. 2003..In this article, we challenge the intactness assumptions, using evidence from a wide variety of studies of toddlers, children, and adults with Williams syndrome... - Brain bioenergetics and cognitive abilityCaroline Rae
Russell Cairns Unit, Radcliffe Infirmary, The University of Oxford, Oxford, UK
Dev Neurosci 25:324-31. 2003..We assessed how these observations may be interpreted in the context of a metabolic vs. histological debate... - Different approaches to relating genotype to phenotype in developmental disordersAnnette Karmiloff-Smith
Neurocognitive Development Unit, Institute of Child Health, London, WC1 1EH, England
Dev Psychobiol 40:311-22. 2002.... - The tortuous route from genes to behavior: A neuroconstructivist approachAnnette Karmiloff-Smith
University College London, London, England
Cogn Affect Behav Neurosci 6:9-17. 2006.... - Visual search in typically developing toddlers and toddlers with Fragile X or Williams syndromeGaia Scerif
Neurocognitive Development Unit, Institute of Child Health, University College London, UK
Dev Sci 7:116-30. 2004..These findings provide information on how visual search typically develops in toddlers, and reveal distinct search deficits for atypically developing toddlers... - Asynchrony in the cognitive and lexical development of young children with Williams syndromeThierry Nazzi
Laboratoire Cognition et Developpement, CNRS, Paris, France
J Child Lang 32:427-38. 2005.... - GTF2IRD1 in craniofacial development of humans and miceMay Tassabehji
Academic Unit of Medical Genetics, University of Manchester, St Mary s Hospital, Manchester M13 9PL, UK
Science 310:1184-7. 2005..We propose a mechanism of cumulative dosage effects of duplicated and diverged genes applicable to other human chromosomal disorders... - What makes counting count? Verbal and visuo-spatial contributions to typical and atypical number developmentDaniel Ansari
Neurocognitive Development Unit, Institute of Child Health, University College, 30 Guilford Street, London WC1N 1EH, UK
J Exp Child Psychol 85:50-62. 2003.... - Are numerical impairments syndrome specific? Evidence from Williams syndrome and Down's syndromeSarah J Paterson
Neurocognitive Development Unit, Institute of Child Health, UCL London, 30 Guilford Street, London WC1N 1EH, UK
J Child Psychol Psychiatry 47:190-204. 2006..Five experiments assessed number skills in these two genetic syndromes and in their mental age (MA) and chronological age (CA) matched controls... - Spatial representation and attention in toddlers with Williams syndrome and Down syndromeJanice H Brown
Department of Psychology, The Harry Pitt Building, University of Reading, Earley Gate, Reading RG6 6AL, UK
Neuropsychologia 41:1037-46. 2003..The findings are also discussed in relation to a possible attention disengagement deficit in WS toddlers. Our study highlights the importance of studying genetic disorders early in development...