Annette Karmiloff-Smith

Summary

Affiliation: University of London
Country: UK

Publications

  1. ncbi What can developmental disorders tell us about the neurocomputational constraints that shape development? The case of Williams syndrome
    Annette Karmiloff-Smith
    Neurocognitive Development Unit, Institute of Child Health, London, United Kingdom
    Dev Psychopathol 15:969-90. 2003
  2. ncbi Williams syndrome
    Annette Karmiloff-Smith
    Centre for Brain and Cognitive Development, School of Psychology, Birkbeck, University of London, 32 Torrington Square, London WC1E 7HX, UK
    Curr Biol 17:R1035-6. 2007
  3. pmc Social cognition in williams syndrome: genotype/phenotype insights from partial deletion patients
    Annette Karmiloff-Smith
    Birkbeck Centre for Brain and Cognitive Development, University of London London, UK
    Front Psychol 3:168. 2012
  4. pmc Genetic and environmental vulnerabilities in children with neurodevelopmental disorders
    Annette Karmiloff-Smith
    Department of Psychological Sciences, Birkbeck Centre for Brain and Cognitive Development, London WC1N 7HX, United Kingdom
    Proc Natl Acad Sci U S A 109:17261-5. 2012
  5. doi Challenging the use of adult neuropsychological models for explaining neurodevelopmental disorders: developed versus developing brains
    Annette Karmiloff-Smith
    Centre for Brain and Cognitive Development, Birkbeck, University of London, London, UK
    Q J Exp Psychol (Hove) 66:1-14. 2013
  6. doi Perspectives on the dynamic development of cognitive capacities: insights from Williams syndrome
    Annette Karmiloff-Smith
    Birkbeck Centre for Brain and Cognitive Development, University of London, London, UK
    Curr Opin Neurol 25:106-11. 2012
  7. doi Neuroimaging of the developing brain: taking "developing" seriously
    Annette Karmiloff-Smith
    Birkbeck Centre for Brain and Cognitive Development, University of London, London, United Kingdom
    Hum Brain Mapp 31:934-41. 2010
  8. doi Nativism versus neuroconstructivism: rethinking the study of developmental disorders
    Annette Karmiloff-Smith
    Birkbeck College, University of London, UK
    Dev Psychol 45:56-63. 2009
  9. ncbi Atypical epigenesis
    Annette Karmiloff-Smith
    Developmental Neurocognition Lab, Birkbeck, University of London, London, UK
    Dev Sci 10:84-8. 2007
  10. ncbi Comprehension of metaphor and metonymy in children with Williams syndrome
    Dagmara Annaz
    School of Psychology, Birkbeck, University of London, London, UK
    Int J Lang Commun Disord 44:962-78. 2009

Detail Information

Publications53

  1. ncbi What can developmental disorders tell us about the neurocomputational constraints that shape development? The case of Williams syndrome
    Annette Karmiloff-Smith
    Neurocognitive Development Unit, Institute of Child Health, London, United Kingdom
    Dev Psychopathol 15:969-90. 2003
    ....
  2. ncbi Williams syndrome
    Annette Karmiloff-Smith
    Centre for Brain and Cognitive Development, School of Psychology, Birkbeck, University of London, 32 Torrington Square, London WC1E 7HX, UK
    Curr Biol 17:R1035-6. 2007
  3. pmc Social cognition in williams syndrome: genotype/phenotype insights from partial deletion patients
    Annette Karmiloff-Smith
    Birkbeck Centre for Brain and Cognitive Development, University of London London, UK
    Front Psychol 3:168. 2012
    ..We discuss the implications of these findings for genotype/phenotype relations, as well as the advantages and limitations of animal models and of case study approaches...
  4. pmc Genetic and environmental vulnerabilities in children with neurodevelopmental disorders
    Annette Karmiloff-Smith
    Department of Psychological Sciences, Birkbeck Centre for Brain and Cognitive Development, London WC1N 7HX, United Kingdom
    Proc Natl Acad Sci U S A 109:17261-5. 2012
    ....
  5. doi Challenging the use of adult neuropsychological models for explaining neurodevelopmental disorders: developed versus developing brains
    Annette Karmiloff-Smith
    Centre for Brain and Cognitive Development, Birkbeck, University of London, London, UK
    Q J Exp Psychol (Hove) 66:1-14. 2013
    ....
  6. doi Perspectives on the dynamic development of cognitive capacities: insights from Williams syndrome
    Annette Karmiloff-Smith
    Birkbeck Centre for Brain and Cognitive Development, University of London, London, UK
    Curr Opin Neurol 25:106-11. 2012
    ....
  7. doi Neuroimaging of the developing brain: taking "developing" seriously
    Annette Karmiloff-Smith
    Birkbeck Centre for Brain and Cognitive Development, University of London, London, United Kingdom
    Hum Brain Mapp 31:934-41. 2010
    ..Thus, a distinction needs to be drawn between child neuroimaging and developmental neuroimaging, the latter approach being relevant not just to children, but to adults and the ageing brain...
  8. doi Nativism versus neuroconstructivism: rethinking the study of developmental disorders
    Annette Karmiloff-Smith
    Birkbeck College, University of London, UK
    Dev Psychol 45:56-63. 2009
    ..e., the emergent property over developmental time of dynamic, multidirectional interactions between genes, brain, cognition, behavior, and environment) with domain-specific outcomes impossible without the process of development...
  9. ncbi Atypical epigenesis
    Annette Karmiloff-Smith
    Developmental Neurocognition Lab, Birkbeck, University of London, London, UK
    Dev Sci 10:84-8. 2007
    ..Atypical epigenesis may often involve a lack of specialization and localization of brain function over developmental time, even in cases of behavioural proficiency...
  10. ncbi Comprehension of metaphor and metonymy in children with Williams syndrome
    Dagmara Annaz
    School of Psychology, Birkbeck, University of London, London, UK
    Int J Lang Commun Disord 44:962-78. 2009
    ..Few studies have investigated metaphor comprehension in Williams syndrome and none has investigated metonymy...
  11. doi Developing spatial frequency biases for face recognition in autism and Williams syndrome
    Hayley C Leonard
    Centre for Brain and Cognitive Development, School of Psychological Sciences, Birkbeck, University of London, Malet Street, London WC1E 7HX, UK
    J Autism Dev Disord 41:968-73. 2011
    ..These data demonstrate that typical outcomes can be achieved through atypical developmental processes, and confirm the importance of cross-syndrome studies in the investigation of developmental disorders...
  12. doi Using developmental trajectories to understand developmental disorders
    Michael S C Thomas
    Developmental Neurocognition Laboratoy, School of Psychology, Birkbeck College, University of London, London, UK
    J Speech Lang Hear Res 52:336-58. 2009
    ..In this article, the authors present a tutorial on the use of developmental trajectories for studying language and cognitive impairments in developmental disorders and compare this method with the use of matching...
  13. doi Cross syndrome comparison of sleep problems in children with Down syndrome and Williams syndrome
    Anna Ashworth
    Department of Psychology and Human Development, Institute of Education, London, UK
    Res Dev Disabil 34:1572-80. 2013
    ..Sleep problems in DS and WS are common and appear to be syndrome-specific. Due to the inaccuracy of parent report, it is recommended that children at risk undergo objective measures of sleep assessment...
  14. doi The development of metaphorical language comprehension in typical development and in Williams syndrome
    Michael S C Thomas
    Developmental Neurocognition Lab, School of Psychology, Birkbeck College, University of London, London WC1E 7HX, UK
    J Exp Child Psychol 106:99-114. 2010
    ..Results indicated that individuals with Williams syndrome may access different, less abstract knowledge in figurative language comparisons despite the relatively strong verbal abilities found in this disorder...
  15. ncbi ERP abnormalities of illusory contour perception in Williams syndrome
    Sarah J Grice
    Centre for Brain and Cognitive Development, School of Psychology, Birkbeck College, University of London, Malet Street, London WC1E 7HX
    Neuroreport 14:1773-7. 2003
    ..We conclude that, contrary to earlier claims, there is atypical neural processing during low-level visual perception in Williams syndrome...
  16. ncbi Exploring the Williams syndrome face-processing debate: the importance of building developmental trajectories
    Annette Karmiloff-Smith
    Neurocognitive Development Unit, Institute of Child Health, London, UK
    J Child Psychol Psychiatry 45:1258-74. 2004
    ..Measurement of evoked brain potentials also point to atypical processes. However, two recent studies have claimed that people with WS process faces exactly like normal controls...
  17. doi A cross-syndrome study of the development of holistic face recognition in children with autism, Down syndrome, and Williams syndrome
    Dagmara Annaz
    Developmental Neurocognition Lab, School of Psychology, Birkbeck College, University of London, London, UK
    J Exp Child Psychol 102:456-86. 2009
    ..We discuss the implications for theories of face recognition in both atypical and typical development, including the idea that part-whole and rotation manipulations may tap different aspects of holistic and/or configural processing...
  18. doi The development of spatial frequency biases in face recognition
    Hayley C Leonard
    Centre for Brain and Cognitive Development, School of Psychology, Birkbeck, University of London, UK
    J Exp Child Psychol 106:193-207. 2010
    ..This suggests that specialization toward the mid-band for upright face recognition develops gradually during childhood and may relate to an advanced level of face expertise...
  19. ncbi Typical and atypical development of visual estimation abilities
    Daniel Ansari
    Neurocognitive Development Unit, Institute of Child Health, London, UK
    Cortex 43:758-68. 2007
    ....
  20. ncbi In-depth analysis of spatial cognition in Williams syndrome: A critical assessment of the role of the LIMK1 gene
    Victoria Gray
    Psychology Department, Royal Holloway, University of London, UK
    Neuropsychologia 44:679-85. 2006
    ..We conclude that a deeper assessment of WS at the genetic level is required before the contribution of specific genes to phenotypic outcomes can be fully understood...
  21. ncbi Are developmental disorders like cases of adult brain damage? Implications from connectionist modelling
    Michael Thomas
    Neurocognitive Development Unit, Institute of Child Health and School of Psychology, Birkbeck College, University of London, London WC1E 7HX, United Kingdom
    Behav Brain Sci 25:727-50; discussion 750-87. 2002
    ....
  22. doi When modularization fails to occur: a developmental perspective
    Dean D'Souza
    Birkbeck Centre for Brain and Cognitive Development, University of London, London, UK
    Cogn Neuropsychol 28:276-87. 2011
    ..In other words, in neurodevelopmental disorders the gradual process of relative modularization may fail to occur...
  23. doi Mechanisms of developmental regression in autism and the broader phenotype: a neural network modeling approach
    Michael S C Thomas
    Developmental Neurocognition Lab, Centre for Brain and Cognitive Development, Department of Psychological Sciences, Birkbeck, University of London, Malet Street, London WC1E 7HX, United Kingdom
    Psychol Rev 118:637-54. 2011
    ..1999). We make a novel prediction that the earliest developmental symptoms in the emergence of autism should be sensory and motor rather than social and review empirical data offering preliminary support for this prediction...
  24. ncbi Love is... an abstract word: the influence of lexical semantics on verbal short-term memory in Williams syndrome
    Emma Laing
    Institute of Child Health, London, UK
    Cortex 41:169-79. 2005
    ..The results demonstrate that, despite claims to the contrary, children and adults with WS are able to access and make use of lexical semantics in a verbal short-term memory task in a manner comparable to typically developing individuals...
  25. ncbi Modeling language acquisition in atypical phenotypes
    Michael S C Thomas
    Institute of Child Health, Neurocognitive Development Unit, London, England
    Psychol Rev 110:647-82. 2003
    ....
  26. doi Sleep enhances memory consolidation in children
    Anna Ashworth
    Department of Psychology and Human Development, Institute of Education, London, UK
    J Sleep Res 23:302-8. 2014
    ..If such experimental sleep-related learning enhancement is generalizable to everyday life, then it is clear that sleep plays a vital role in children's educational attainment. ..
  27. pmc Discriminating power of localized three-dimensional facial morphology
    Peter Hammond
    Eastman Dental Institute, University College London, London, WC1X 8LD, United Kingdom
    Am J Hum Genet 77:999-1010. 2005
    ....
  28. ncbi Neuroimaging of typical and atypical development: a perspective from multiple levels of analysis
    Mark H Johnson
    Centre for Brain and Cognitive Development, School of Psychology, Birkbeck College, University of London, UK
    Dev Psychopathol 14:521-36. 2002
    ....
  29. doi The dynamics of ontogeny: a neuroconstructivist perspective on genes, brains, cognition and behavior
    Tessa M Dekker
    Birkbeck Centre for Brain and Cognitive Development, University of London, London, UK
    Prog Brain Res 189:23-33. 2011
    ..Finally, we discuss future contributions of the neuroconstructivist approach to developmental research in particular, and cognitive neuroscience in general...
  30. doi Definitions versus categorization: assessing the development of lexico-semantic knowledge in Williams syndrome
    Harry R M Purser
    Department of Psychology and Human Development, Institute of Education, University of London, London, UK
    Int J Lang Commun Disord 46:361-73. 2011
    ..Williams syndrome (WS) is associated with relatively strong language abilities despite mild to moderate intellectual disability, particularly when language is indexed by vocabulary...
  31. doi The over-pruning hypothesis of autism
    Michael S C Thomas
    Developmental Neurocognition Lab, Centre for Brain and Cognitive Development, Birkbeck, University of London, UK
    Dev Sci 19:284-305. 2016
    ..the implication of observed similarities between individuals with autism and their family members); and integrates data from multiple disciplines, including behavioural studies, neuroscience studies, genetics, and intervention studies. ..
  32. pmc Concurrent Relations between Face Scanning and Language: A Cross-Syndrome Infant Study
    Dean D'Souza
    Centre for Brain and Cognitive Development, Department of Psychological Sciences, Birkbeck, University of London, London, United Kingdom
    PLoS ONE 10:e0139319. 2015
    ..It also raises the possibility that syndrome-specific interventions should include an early focus on efficient face-scanning behaviour. ..
  33. pmc Audio-visual speech perception: a developmental ERP investigation
    Victoria C P Knowland
    School of Health Sciences, City University, London, UK Department of Psychological Sciences, Birkbeck College, London, UK
    Dev Sci 17:110-24. 2014
    ..These data suggest that auditory ERP modulation by visual speech represents separable underlying cognitive processes, some of which show earlier maturation than others over the course of development. ..
  34. ncbi Double dissociations in developmental disorders? Theoretically misconceived, empirically dubious
    Annette Karmiloff-Smith
    Neurocognitive Development Unit, Institute of Child Health, London, UK
    Cortex 39:161-3. 2003
  35. ncbi Early categorization abilities in young children with Williams syndrome
    Thierry Nazzi
    Neurocognitive Development Unit, Institute of Child Health, London, UK
    Neuroreport 13:1259-62. 2002
    ..The present study hence supports the claim that vocabulary acquisition in Williams syndrome develops atypically...
  36. doi Characterisation of sleep problems in children with Williams syndrome
    Dagmara Annaz
    School of Health and Social Science, Middlesex University, London, UK
    Res Dev Disabil 32:164-9. 2011
    ..Furthermore the negative impact of sleep disturbances on daytime behaviour and learning should be measured before diagnoses of behaviourally defined disorders are considered...
  37. doi Discovering structure in auditory input: evidence from Williams syndrome
    Mayada Elsabbagh
    Centre for Brain and Cognitive Development, Birkbeck, University of London, London
    Am J Intellect Dev Disabil 115:128-39. 2010
    ..Unlike controls who demonstrated greater proficiency when contour cues were available, adults with Williams syndrome showed no such advantage...
  38. doi Attention across modalities as a longitudinal predictor of early outcomes: the case of fragile X syndrome
    Gaia Scerif
    Attention, Brain and Cognitive Development Group, Department of Experimental Psychology, University of Oxford, Oxford, UK
    J Child Psychol Psychiatry 53:641-50. 2012
    ..FXS therefore represents an ideal model disorder to study prospectively the impact of early attention deficits on behaviour...
  39. doi The missing developmental dimension in the network perspective
    Sam Wass
    Centre for Brain and Cognitive Development, Birkbeck College, University of London, London WC1E 7HX, United Kingdom
    Behav Brain Sci 33:175-6. 2010
    ..We discuss principles such as fan in, fan out, bottlenecks, and common pathways, and argue that modelling these developmental aspects can be vital, particularly in deriving properly targeted treatments...
  40. ncbi The dawn of cognitive genetics? Crucial developmental caveats
    Gaia Scerif
    School of Psychology, University of Nottingham, Nottingham, UK
    Trends Cogn Sci 9:126-35. 2005
    ..Most importantly, interdisciplinary efforts to integrate human genetics and cognition will need to operationalize the mechanisms driving both typical and atypical developmental processes over time...
  41. ncbi A study of relative clauses in Williams syndrome
    Julia Grant
    Neurocognitive Development Unit, Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
    J Child Lang 29:403-16. 2002
    ....
  42. ncbi Tracing syndrome-specific trajectories of attention across the lifespan
    Kim Cornish
    Neuroscience Laboratory for Research and Education in Children with Developmental Disorders, McGill University, Montreal, Canada
    Cortex 43:672-85. 2007
    ....
  43. ncbi Comprehension of spatial language terms in Williams syndrome: evidence for an interaction between domains of strength and weakness
    Caroline E Phillips
    Centre for the Study of Memory and Learning, Department of Experimental Psychology, University of Bristol, UK
    Cortex 40:85-101. 2004
    ..They also shed light on the ways in which spatial cognition may interact with language comprehension more generally...
  44. ncbi GTF2IRD1 in craniofacial development of humans and mice
    May Tassabehji
    Academic Unit of Medical Genetics, University of Manchester, St Mary s Hospital, Manchester M13 9PL, UK
    Science 310:1184-7. 2005
    ..We propose a mechanism of cumulative dosage effects of duplicated and diverged genes applicable to other human chromosomal disorders...
  45. ncbi Dethroning the myth: cognitive dissociations and innate modularity in Williams syndrome
    Annette Karmiloff-Smith
    ICH Neurocognitive Development Unit, London, England
    Dev Neuropsychol 23:227-42. 2003
    ..In this article, we challenge the intactness assumptions, using evidence from a wide variety of studies of toddlers, children, and adults with Williams syndrome...
  46. ncbi Spatial representation and attention in toddlers with Williams syndrome and Down syndrome
    Janice H Brown
    Department of Psychology, The Harry Pitt Building, University of Reading, Earley Gate, Reading RG6 6AL, UK
    Neuropsychologia 41:1037-46. 2003
    ..The findings are also discussed in relation to a possible attention disengagement deficit in WS toddlers. Our study highlights the importance of studying genetic disorders early in development...
  47. ncbi What makes counting count? Verbal and visuo-spatial contributions to typical and atypical number development
    Daniel Ansari
    Neurocognitive Development Unit, Institute of Child Health, University College, 30 Guilford Street, London WC1N 1EH, UK
    J Exp Child Psychol 85:50-62. 2003
    ....
  48. ncbi Brain bioenergetics and cognitive ability
    Caroline Rae
    Russell Cairns Unit, Radcliffe Infirmary, The University of Oxford, Oxford, UK
    Dev Neurosci 25:324-31. 2003
    ..We assessed how these observations may be interpreted in the context of a metabolic vs. histological debate...
  49. ncbi The tortuous route from genes to behavior: A neuroconstructivist approach
    Annette Karmiloff-Smith
    University College London, London, England
    Cogn Affect Behav Neurosci 6:9-17. 2006
    ....
  50. ncbi Visual search in typically developing toddlers and toddlers with Fragile X or Williams syndrome
    Gaia Scerif
    Neurocognitive Development Unit, Institute of Child Health, University College London, UK
    Dev Sci 7:116-30. 2004
    ..These findings provide information on how visual search typically develops in toddlers, and reveal distinct search deficits for atypically developing toddlers...
  51. ncbi Asynchrony in the cognitive and lexical development of young children with Williams syndrome
    Thierry Nazzi
    Laboratoire Cognition et Developpement, CNRS, Paris, France
    J Child Lang 32:427-38. 2005
    ....
  52. ncbi Are numerical impairments syndrome specific? Evidence from Williams syndrome and Down's syndrome
    Sarah J Paterson
    Neurocognitive Development Unit, Institute of Child Health, UCL London, 30 Guilford Street, London WC1N 1EH, UK
    J Child Psychol Psychiatry 47:190-204. 2006
    ..Five experiments assessed number skills in these two genetic syndromes and in their mental age (MA) and chronological age (CA) matched controls...
  53. ncbi Different approaches to relating genotype to phenotype in developmental disorders
    Annette Karmiloff-Smith
    Neurocognitive Development Unit, Institute of Child Health, London, WC1 1EH, England
    Dev Psychobiol 40:311-22. 2002
    ....