Research Topics
Genomes and GenesSpecies | David KaneSummaryAffiliation: University of Newcastle Country: UK Publications
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Detail Information
Publications
Early psoriatic arthritisDavid Kane
School of Clinical and Medical Sciences, University of Newcastle upon Tyne, Framlington Place, Cookson Building, Newcastle upon Tyne NE2 4HH, UK
Rheum Dis Clin North Am 31:641-57. 2005..This article reviews the clinical features of early PsA, pathologic insights into PsA gleaned from studies of early PsA, and the current state of diagnostic imaging and therapeutics in early PsA...
The role of ultrasound in the diagnosis and management of psoriatic arthritisDavid Kane
University of Newcastle upon Tyne, School of Clinical and Medical Sciences Rheumatology, Cookson Building, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK
Curr Rheumatol Rep 7:319-24. 2005....
Musculoskeletal ultrasound--a state of the art review in rheumatology. Part 1: Current controversies and issues in the development of musculoskeletal ultrasound in rheumatologyD Kane
School of Clinical and Medical Sciences Rheumatology, Cookson Building, Framlington Place, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK
Rheumatology (Oxford) 43:823-8. 2004..This paper reviews how MSUS in rheumatology has evolved and the controversies and issues that rheumatologists must now address in developing MSUS as an indispensable, everyday clinical tool...
Protective effect of sensory denervation in inflammatory arthritis (evidence of regulatory neuroimmune pathways in the arthritic joint)D Kane
School of Clinical and Medical Sciences Rheumatology, 4th Floor, Cookson Building, Framlington Place, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK
Ann Rheum Dis 64:325-7. 2005..Plain radiography, ultrasonography and nerve conduction studies of the hands confirmed the absence of articular disease and sensory innervation in the left 4th digit...
Musculoskeletal ultrasound--a state of the art review in rheumatology. Part 2: Clinical indications for musculoskeletal ultrasound in rheumatologyD Kane
School of Clinical and Medical Sciences Rheumatology, Cookson Building, Framlington Place, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, UK
Rheumatology (Oxford) 43:829-38. 2004..This paper reviews the evidence for the application of MSUS in rheumatology...
Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexateDavid Kane
St Vincent s University Hospital, Dublin, Ireland
Arthritis Rheum 50:3286-95. 2004..In this study, we sought to determine the effects of methotrexate on the inflammatory infiltrate and on cytokine and metalloproteinase gene expression in the synovium of PsA patients...
Increased perivascular synovial membrane expression of myeloid-related proteins in psoriatic arthritisDavid Kane
Department of Rheumatology, St Vincent's University Hospital, Dublin, Ireland
Arthritis Rheum 48:1676-85. 2003..Moreover, MRP expression is reduced following MTX treatment. MRP proteins may represent a novel therapeutic target in inflammatory arthritis...
A randomized, double-blind, controlled study of ultrasound-guided corticosteroid injection into the joint of patients with inflammatory arthritisJoanna Cunnington
Freeman Hospital and Newcastle University, Newcastle upon Tyne, UK
Arthritis Rheum 62:1862-9. 2010..The aim of this study was to investigate whether ultrasound (US) guidance improves the accuracy and clinical outcome of joint injections as compared with CE guidance in patients with inflammatory arthritis...
Cytokine gene polymorphisms: association with psoriatic arthritis susceptibility and severityJoanna Balding
Smurfit Institute, Trinity College, Dublin, Ireland
Arthritis Rheum 48:1408-13. 2003..To determine whether functional cytokine gene polymorphisms influence disease susceptibility and phenotype in patients with psoriatic arthritis (PsA)...
Attitudes of United Kingdom rheumatologists to musculoskeletal ultrasound practice and trainingJoanna Cunnington
School of Clinical and Medical Sciences Rheumatology, University of Newcastle upon Tyne, UK
Ann Rheum Dis 66:1381-3. 2007....
A rheumatologist's perspective on musculoskeletal ultrasound in rheumatology: comment on the editorial by Roemer et alDavid Kane
Arthritis Rheum 55:341-2; author reply 343-4. 2006
Musculoskeletal ultrasound including definitions for ultrasonographic pathologyRichard J Wakefield
Academic Unit of Musculoskeletal Disease, University of Leeds, Leeds, UK
J Rheumatol 32:2485-7. 2005..Also proposed for the first time are consensus US definitions for common pathological lesions seen in patients with inflammatory arthritis...
Modulation of orphan nuclear receptor NURR1 expression by methotrexate in human inflammatory joint disease involves adenosine A2A receptor-mediated responsesJennifer A Ralph
Department of Veterinary Biochemistry and Physiology, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland
J Immunol 175:555-65. 2005....
Quantitation of metalloproteinase gene expression in rheumatoid and psoriatic arthritis synovial tissue distal and proximal to the cartilage-pannus junctionDavid Kane
Department of Rheumatology, St. Vincent's University Hospital, Dublin 4, Ireland
J Rheumatol 31:1274-80. 2004..The different patterns of radiological progression seen in RA and PsA were not explained by differences in synovial mRNA expression of MMP-1, MMP-3, or TIMP-1...
Tumor necrosis factor-alpha in psoriasis and psoriatic arthritis: a clinical, genetic, and histopathologic perspectiveDavid Kane
Department of Rheumatology, St. Vincent's University Hospital, Elm Park, Dublin, 4 Ireland
Curr Rheumatol Rep 6:292-8. 2004..In this paper, the emerging immunohistochemical, genetic, and clinical literature relating to TNF's role in skin and joint manifestations of this disease is reviewed and areas for future research are suggested...
Effects of tumor necrosis factor blockade on cardiovascular risk factors in psoriatic arthritis: a double-blind, placebo-controlled studyNaveed Sattar
University of Glasgow, Glasgow, UK
Arthritis Rheum 56:831-9. 2007....
Summary findings of a systematic review of the ultrasound assessment of synovitisFredrick Joshua
Department of Rheumatology, St George Hospital, University of NSW, Sydney, Australia
J Rheumatol 34:839-47. 2007..The review highlights the current gaps in the literature, including a lack of reliability data with respect to intra-occasion and intra- and inter-reader reliability. Current work by our group is addressing these issues...
"All that glistens is not gold"--separating artefacts from true Doppler signals in rheumatological ultrasoundPeter V Balint
Ann Rheum Dis 67:141-2. 2008
Ultrasound guided versus conventional joint and soft tissue fluid aspiration in rheumatology practice: a pilot studyPeter V Balint
Centre for Rheumatic Diseases, University Department of Medicine, Glasgow Royal Infirmary, Glasgow, Scotland
J Rheumatol 29:2209-13. 2002..To compare joint and soft tissue aspiration using a conventional technique with an ultrasound (US) guided technique...
