N Kalia

Summary

Affiliation: University of Sheffield
Country: UK

Publications

  1. ncbi request reprint Mast cell stabilization prevents ethanol-induced rat gastric mucosal injury: mechanisms of protection
    N Kalia
    Department of Surgical and Anaesthetic Sciences, Royal Hallamshire Hospital, Sheffield, United Kingdom
    J Gastroenterol Hepatol 15:133-41. 2000
  2. ncbi request reprint Of blood and guts: association between Helicobacter pylori and the gastric microcirculation
    Neena Kalia
    Department of Biomedical Sciences, Alfred Denny Building, Western Bank, University of Sheffield, Sheffield S10 2TN, UK
    J Gastroenterol Hepatol 18:1010-7. 2003
  3. ncbi request reprint Mucosal villus microcirculatory disturbances associated with rat intestinal ischaemia-reperfusion injury are not prevented by tacrolimus
    Neena Kalia
    Department of Biomedical Science, Alfred Denny Building, Western Bank, University of Sheffield, Sheffield, UK
    Digestion 67:154-60. 2003
  4. pmc Toxigenic Helicobacter pylori induces changes in the gastric mucosal microcirculation in rats
    N Kalia
    Section of Surgical and Anaesthetic Sciences, Division of Clinical Sciences S, Royal Hallamshire Hospital, Sheffield, UK
    Gut 51:641-7. 2002
  5. ncbi request reprint FK409 inhibits both local and remote organ damage after intestinal ischaemia
    Neena Kalia
    Surgical and Anaesthetic Sciences, Division of Clinical Sciences South, University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
    J Pathol 197:595-602. 2002
  6. pmc Effects of hypothermia and rewarming on the mucosal villus microcirculation and survival after rat intestinal ischemia-reperfusion injury
    Neena Kalia
    Division of Clinical Sciences South, University of Sheffield, Royal Hallamshire Hospital, UK
    Ann Surg 236:67-74. 2002
  7. ncbi request reprint L-Arginine protects and exacerbates ethanol-induced rat gastric mucosal injury
    N Kalia
    Department of Surgical and Anaesthetic Sciences, Royal Hallamshire Hospital, Sheffield, United Kingdom
    J Gastroenterol Hepatol 15:915-24. 2000
  8. ncbi request reprint Effects of FK409 on intestinal ischemia-reperfusion injury and ischemia-induced changes in the rat mucosal villus microcirculation
    N Kalia
    Section of Surgical and Anesthetic Sciences, Division of Clinical Sciences (CSUH, Royal Hallamshire Hospital, Sheffield, S10 2JF, UK
    Transplantation 72:1875-80. 2001
  9. ncbi request reprint Effects of genotypically different strains of Helicobacter pylori on human microvascular endothelial cells in vitro
    N Kalia
    Department of Surgical and Anaesthetic Sciences, Royal Hallamshire Hospital, University of Sheffield, UK
    Dig Dis Sci 46:54-61. 2001
  10. ncbi request reprint Effects of intestinal ischemia-reperfusion injury on rat peripheral blood neutrophil activation
    N Kalia
    Department of Biomedical Science, University of Sheffield, UK
    Dig Dis Sci 48:1677-84. 2003

Detail Information

Publications17

  1. ncbi request reprint Mast cell stabilization prevents ethanol-induced rat gastric mucosal injury: mechanisms of protection
    N Kalia
    Department of Surgical and Anaesthetic Sciences, Royal Hallamshire Hospital, Sheffield, United Kingdom
    J Gastroenterol Hepatol 15:133-41. 2000
    ..Fluorescent in vivo microscopy was used to assess the effects of ketotifen, a mast cell stabilizer, and pyrilamine, a histamine (H1)-receptor antagonist, on ethanol-induced rat gastric mucosal injury...
  2. ncbi request reprint Of blood and guts: association between Helicobacter pylori and the gastric microcirculation
    Neena Kalia
    Department of Biomedical Sciences, Alfred Denny Building, Western Bank, University of Sheffield, Sheffield S10 2TN, UK
    J Gastroenterol Hepatol 18:1010-7. 2003
    ..pylori infection and coronary heart disease. The present review highlights the major findings from these studies and proposes an important role for the gastric microcirculation in the pathophysiology of H. pylori-induced injury...
  3. ncbi request reprint Mucosal villus microcirculatory disturbances associated with rat intestinal ischaemia-reperfusion injury are not prevented by tacrolimus
    Neena Kalia
    Department of Biomedical Science, Alfred Denny Building, Western Bank, University of Sheffield, Sheffield, UK
    Digestion 67:154-60. 2003
    ..However, its effects on intestinal I/R injury have not been evaluated...
  4. pmc Toxigenic Helicobacter pylori induces changes in the gastric mucosal microcirculation in rats
    N Kalia
    Section of Surgical and Anaesthetic Sciences, Division of Clinical Sciences S, Royal Hallamshire Hospital, Sheffield, UK
    Gut 51:641-7. 2002
    ..This study used fluorescent in vivo microscopy to determine the acute effects of extracts of genotypically different H pylori strains on the GMMC...
  5. ncbi request reprint FK409 inhibits both local and remote organ damage after intestinal ischaemia
    Neena Kalia
    Surgical and Anaesthetic Sciences, Division of Clinical Sciences South, University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK
    J Pathol 197:595-602. 2002
    ..FK409 may therefore be of value in reducing both local and remote tissue damage and improving outcome in situations where intestinal I/R injury is obligatory, such as small bowel transplantation...
  6. pmc Effects of hypothermia and rewarming on the mucosal villus microcirculation and survival after rat intestinal ischemia-reperfusion injury
    Neena Kalia
    Division of Clinical Sciences South, University of Sheffield, Royal Hallamshire Hospital, UK
    Ann Surg 236:67-74. 2002
    ..To determine the effects of hypothermia and rewarming on changes in the villus microcirculation induced by intestinal ischemia-reperfusion (I/R)...
  7. ncbi request reprint L-Arginine protects and exacerbates ethanol-induced rat gastric mucosal injury
    N Kalia
    Department of Surgical and Anaesthetic Sciences, Royal Hallamshire Hospital, Sheffield, United Kingdom
    J Gastroenterol Hepatol 15:915-24. 2000
    ..This study used fluorescent in vivo microscopy to investigate (i) whether L-arginine (NO precursor) prevented EtOH induced injury and (ii) the mechanisms of protection...
  8. ncbi request reprint Effects of FK409 on intestinal ischemia-reperfusion injury and ischemia-induced changes in the rat mucosal villus microcirculation
    N Kalia
    Section of Surgical and Anesthetic Sciences, Division of Clinical Sciences (CSUH, Royal Hallamshire Hospital, Sheffield, S10 2JF, UK
    Transplantation 72:1875-80. 2001
    ....
  9. ncbi request reprint Effects of genotypically different strains of Helicobacter pylori on human microvascular endothelial cells in vitro
    N Kalia
    Department of Surgical and Anaesthetic Sciences, Royal Hallamshire Hospital, University of Sheffield, UK
    Dig Dis Sci 46:54-61. 2001
    ..This suggests that microcirculatory disturbances observed in vivo may not be the result of direct endothelial cell damage. However, inhibition of angiogenesis may explain why ulcer healing is delayed in H. pylori-infected patients...
  10. ncbi request reprint Effects of intestinal ischemia-reperfusion injury on rat peripheral blood neutrophil activation
    N Kalia
    Department of Biomedical Science, University of Sheffield, UK
    Dig Dis Sci 48:1677-84. 2003
    ..Monitoring the peripheral blood for activated neutrophils is of no value in assessing the severity of direct intestinal I/R injury or predicting remote organ damage after intestinal ischemia...
  11. ncbi request reprint Effects of aspirin and indomethacin on endothelial cell proliferation in vitro
    H R Pearce
    Academic Unit of Surgery, Division of Clinical Sciences, Royal Hallamshire Hospital, University of Sheffield, Sheffield, UK
    J Gastroenterol Hepatol 18:1180-7. 2003
    ..Ulcer healing is dependent on angiogenesis, which requires endothelial cell (EC) proliferation. The present study aimed to determine whether NSAID and prostaglandin E2 (PGE2) inhibited EC proliferation in vitro...
  12. ncbi request reprint Intestinal secretory and absorptive function in Trichinella spiralis mouse model of postinfective gut dysfunction: role of bile acids
    N Kalia
    Department of Biomedical Science, University of Sheffield, Sheffield, UK
    Gut 57:41-9. 2008
    ..Changes in the protein expression of apical sodium-dependent bile acid transporter (ASBT) were also measured...
  13. ncbi request reprint Ketotifen abrogates local and systemic consequences of rat intestinal ischemia-reperfusion injury
    Neena Kalia
    Academic Unit of Surgical Oncology, Division of Clinical Sciences South, Royal Hallamshire Hospital, Sheffield, UK
    J Gastroenterol Hepatol 20:1032-8. 2005
    ..The purpose of the present study was to evaluate the effects of the mast cell stabilizer, ketotifen, on leukocyte adhesion within, and tissue leakage from the mucosal villous microcirculation after intestinal I/R...
  14. pmc Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow
    Owen J T McCarty
    Centre for Cardiovascular Sciences, The Institute of Biomedical Research, School of Biosciences, University of Birmingham, United Kingdom
    J Biol Chem 280:39474-84. 2005
    ....
  15. ncbi request reprint Effects of Helicobacter pylori on endothelial cell proliferation and chemotaxis
    Hannah Rose Pearce
    Academic Unit of Surgery, Division of Clinical Sciences, Royal Hallamshire Hospital, University of Sheffield, Sheffield S10 2JF, UK
    Digestion 69:201-10. 2004
    ..Ulcer healing is dependent upon angiogenesis, requiring endothelial cell (EC) proliferation and chemotaxis. This study determined whether extracts of H. pylori affected EC proliferation and/or chemotaxis in vitro...
  16. ncbi request reprint Helicobacter pylori prevents proliferative stage of angiogenesis in vitro: role of cytokines
    Lesley Jenkinson
    Division of Clinical Sciences S, Royal Hallamshire Hospital, Sheffield, UK
    Dig Dis Sci 47:1857-62. 2002
    ..In conclusion, H. pylori induces cytokine up-regulation as part of its pathophysiological mechanism, which could prove detrimental to ulcer healing through an inhibitory effect on angiogenesis...
  17. pmc Mechanisms of ANCA-mediated leukocyte-endothelial cell interactions in vivo
    Sarah L Nolan
    Renal Immunobiology, Medical School, University of Birmingham, Birmingham, United Kingdom
    J Am Soc Nephrol 19:973-84. 2008
    ..In addition, it suggests that neutrophils primed by cytokines in the presence of anti-MPO IgG can have systemic effects and target specific vascular beds...