Keisuke Kaji

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc High-resolution analysis with novel cell-surface markers identifies routes to iPS cells
    James O'Malley
    MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh bioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, UK
    Nature 499:88-91. 2013
  2. pmc Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    Keisuke Kaji
    MRC Centre for Regenerative Medicine, Institute for Stem Cell Research, University of Edinburgh, Edinburgh EH9 3JQ, UK
    Nature 458:771-5. 2009
  3. doi request reprint New strategies to generate induced pluripotent stem cells
    James O'Malley
    MRC Centre for Regenerative Medicine, Institute for Stem Cell Research, University of Edinburgh, Edinburgh EH9 3JQ, UK
    Curr Opin Biotechnol 20:516-21. 2009
  4. pmc Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency
    Fella Hammachi
    MRC Centre for Regenerative Medicine Institute for Stem Cell Research, School of Biological Sciences, 5 Little France Drive, University of Edinburgh, EH16 4UU Edinburgh, UK
    Cell Rep 1:99-109. 2012
  5. pmc ERK2 suppresses self-renewal capacity of embryonic stem cells, but is not required for multi-lineage commitment
    William B Hamilton
    MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e60907. 2013

Collaborators

Detail Information

Publications5

  1. pmc High-resolution analysis with novel cell-surface markers identifies routes to iPS cells
    James O'Malley
    MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh bioQuarter, 5 Little France Drive, Edinburgh EH16 4UU, UK
    Nature 499:88-91. 2013
    ..This novel high-resolution analysis enables the construction of a detailed reprogramming route map, and the improved understanding of the reprogramming process will lead to new reprogramming strategies. ..
  2. pmc Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    Keisuke Kaji
    MRC Centre for Regenerative Medicine, Institute for Stem Cell Research, University of Edinburgh, Edinburgh EH9 3JQ, UK
    Nature 458:771-5. 2009
    ....
  3. doi request reprint New strategies to generate induced pluripotent stem cells
    James O'Malley
    MRC Centre for Regenerative Medicine, Institute for Stem Cell Research, University of Edinburgh, Edinburgh EH9 3JQ, UK
    Curr Opin Biotechnol 20:516-21. 2009
    ..This review focus on these evolving strategies to generate genetically unmodified or reprogramming factor-free iPSCs...
  4. pmc Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency
    Fella Hammachi
    MRC Centre for Regenerative Medicine Institute for Stem Cell Research, School of Biological Sciences, 5 Little France Drive, University of Edinburgh, EH16 4UU Edinburgh, UK
    Cell Rep 1:99-109. 2012
    ..At still lower levels of the fusion, LIF dependence was restored. We conclude that the necessary and sufficient function of Oct4 in promoting pluripotency is to activate specific target genes...
  5. pmc ERK2 suppresses self-renewal capacity of embryonic stem cells, but is not required for multi-lineage commitment
    William B Hamilton
    MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom
    PLoS ONE 8:e60907. 2013
    ..We show that ERK2 contributes to the destabilization of ES cell self-renewal by reducing expression of pluripotency genes, such as Nanog, but is not specifically required for the early stages of germ layer specification...