Research Topics
| Eileen M JoyceSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
A volumetric MRI and magnetization transfer imaging follow-up study of patients with first-episode schizophreniaGary Price
Department of Neuroinflammation, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK
Schizophr Res 87:100-8. 2006..The results of the study need to be interpreted in the light of the small sample size and of the limitations of current image analysis methods...
IQ as a predictor of functional outcome in schizophrenia: a longitudinal, four-year study of first-episode psychosisVerity C Leeson
Department of Psychological Medicine, Imperial College London, Charing Cross Campus, St Dunstan s Road, London W6 8RP, UK
Schizophr Res 107:55-60. 2009..This study suggests that early in the course of schizophrenia, general cognitive ability, as measured by IQ, is a more sensitive and reliable predictor of functional outcome than measures of specific ability...- Circadian rhythms and cognition in schizophreniaKatharina Wulff
Professor of Neuropsychiatry, Box 19, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
Br J Psychiatry 198:250-2. 2011..Circadian synchronisation depends on the external input of light-dark cues and the integrity of central nervous system circadian oscillators; these may represent new interventional targets to improve cognition... - Cognitive heterogeneity in schizophreniaEileen M Joyce
UCL Institute of Neurology, London, UK
Curr Opin Psychiatry 20:268-72. 2007.... - Cognitive heterogeneity in first-episode schizophreniaEileen M Joyce
Institute of Neurology, University College London, Box 19, The National Hospital for Neurology and Neurosurgery, Queen Square, London WC1N 3BG, UK
Br J Psychiatry 187:516-22. 2005..Studies of chronic schizophrenia suggest that there are subgroups with different profiles of cognitive impairment... - White matter tracts in first-episode psychosis: a DTI tractography study of the uncinate fasciculusGary Price
Institute of Neurology, University College London, Queen Square, London, UK
Neuroimage 39:949-55. 2008..The SCV of FA was lower in females across both groups and there was no correlation between the SCV of FA and clinical ratings... - IQ trajectory, cognitive reserve, and clinical outcome following a first episode of psychosis: a 3-year longitudinal studyVerity C Leeson
UCL Institute of Neurology, The National Hospital for Neurologyand Neurosurgery, University College London, Queen Square, London, UK
Schizophr Bull 37:768-77. 2011..These data suggest that following psychosis onset, IQ is stable and that it is IQ at psychosis onset rather than premorbid IQ predicts a more severe illness... - Brain pathology in first-episode psychosis: magnetization transfer imaging provides additional information to MRI measurements of volume lossGary Price
Institute of Neurology, University College London, Queen Square, London, UK
Neuroimage 49:185-92. 2010..Magnetization transfer imaging (MTI), a technique more sensitive to subtle neuropathological changes than conventional MRI, could yield important information on the extent and nature of structural abnormalities... - Discrimination learning, reversal, and set-shifting in first-episode schizophrenia: stability over six years and specific associations with medication type and disorganization syndromeVerity C Leeson
UCL Institute of Neurology, London, United Kingdom Imperial College Faculty of Medicine, London, United Kingdom
Biol Psychiatry 66:586-93. 2009..Limited evidence suggests that attentional set-shifting deteriorates over time in schizophrenia. We tested this hypothesis and examined the specificity of learning impairments identified by this task... - Structural neural networks subserving oculomotor function in first-episode schizophreniaManjinder S Bagary
Institute of Neurology, University College London, Queens Square, London WC1N 3BG, United Kingdom
Biol Psychiatry 56:620-7. 2004..CONCLUSIONS: These preliminary results demonstrate that specific structural abnormalities are associated with abnormal eye movements in schizophrenia... - The effect of cannabis use and cognitive reserve on age at onset and psychosis outcomes in first-episode schizophreniaVerity C Leeson
UCL Institute of Neurology, The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
Schizophr Bull 38:873-80. 2012..We aimed to clarify the role of age at onset and cognition on outcomes in cannabis users with first-episode schizophrenia as well as the effect of cannabis dose and cessation of use... - Abnormal brain connectivity in first-episode psychosis: a diffusion MRI tractography study of the corpus callosumGary Price
Department of Neuroinflammation, Institute of Neurology, University College London, Queen Square, London, WC1N 3BG, UK
Neuroimage 35:458-66. 2007..The FA reduction in patients may be due to aberrant myelination or axonal abnormalities, but the similar tract volumes in the two groups suggest that severe axonal loss is unlikely at this stage of the illness... - Is persistent ketamine use a valid model of the cognitive and oculomotor deficits in schizophrenia?Celia J A Morgan
Clinical Psychopharmacology Unit, University College London, United Kingdom
Biol Psychiatry 65:1099-102. 2009..In this study, we investigated the effect of persistent recreational ketamine use on tests of episodic and working memory and on oculomotor tasks of smooth pursuit and pro- and antisaccades... 
A window into the brain: An in vivo study of the retina in schizophrenia using optical coherence tomographyElvina May Yin Chu
Department of Neuropsychiatry, University College London, Institute of Neurology, London, UK Electronic address
Psychiatry Res 203:89-94. 2012..Longitudinal studies using higher resolution OCT will clarify whether progressive RNFL and MV changes occur and whether they can be used as state or trait markers in schizophrenia...- Adaptive and aberrant reward prediction signals in the human brainJonathan P Roiser
Institute of Cognitive Neuroscience, University College London, London, UK
Neuroimage 50:657-64. 2010..The results are discussed in terms of their implications for different theories of associative learning... - Gray and white matter brain abnormalities in first-episode schizophrenia inferred from magnetization transfer imagingManny S Bagary
Department of Neuroinflammation, Institute of Neurology, Queen Square, University College London, England
Arch Gen Psychiatry 60:779-88. 2003..New imaging methods such as magnetization transfer imaging may be more sensitive than conventional volumetric imaging to the subtle structural brain changes in schizophrenia... - Improvement and decline of cognitive function in schizophrenia over one year: a longitudinal investigation using latent growth modellingJennifer H Barnett
University of Cambridge Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
BMC Psychiatry 7:16. 2007..Long-term follow-up studies of people with schizophrenia report stability of cognitive performance; less is known about any shorter-term changes in cognitive function... - Relationship between insight, cognitive function, social function and symptomatology in schizophrenia: the West London first episode studyStanley H Mutsatsa
Department of Psychological Medicine, Imperial College, St Dunstan s Road, London, W6 8RP
Eur Arch Psychiatry Clin Neurosci 256:356-63. 2006..To examine the nature and clinical correlates of insight in first-episode schizophrenia, and how these differ from findings in established schizophrenia... - Comorbid substance use and age at onset of schizophreniaThomas R E Barnes
Department of Psychological Medicine, Imperial College Faculty of Medicine, Charing Cross Campus, St Dunstan s Road, London W6 8RP, UK
Br J Psychiatry 188:237-42. 2006..Substance use may be a risk factor for the onset of schizophrenia... - The relationship between antisaccades, smooth pursuit, and executive dysfunction in first-episode schizophreniaSamuel B Hutton
Department of Psychology, University of Sussex, Brighton, UK
Biol Psychiatry 56:553-9. 2004..CONCLUSIONS: These findings suggest that in schizophrenia working memory and antisaccade performance reflect the same abnormal prefrontal substrates and that smooth pursuit is mediated by a separate neural abnormality... - Gaze strategies during planning in first-episode psychosisVyv C Huddy
Division of Neuroscience and Mental Health, Imperial College London, London, England
J Abnorm Psychol 116:589-98. 2007..This suggests that the patients had difficulty in encoding the essential features of the stimulus array. This finding is compatible with slowing of working memory consolidation...