Catherine L Jopling

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. pmc miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components
    Ashley P E Roberts
    Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK
    Nucleic Acids Res 39:7716-29. 2011
  2. doi request reprint The P body protein LSm1 contributes to stimulation of hepatitis C virus translation, but not replication, by microRNA-122
    Ashley P E Roberts
    School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Nucleic Acids Res 42:1257-69. 2014
  3. pmc Targeting viral infection by microRNA inhibition
    Ashley P E Roberts
    School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Genome Biol 11:201. 2010
  4. pmc Liver-specific microRNA-122: Biogenesis and function
    Catherine Jopling
    Centre for Biomolecular Sciences University of Nottingham University Park Nottingham, UK
    RNA Biol 9:137-42. 2012
  5. doi request reprint Regulation of hepatitis C virus by microRNA-122
    Catherine L Jopling
    Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, UK
    Biochem Soc Trans 36:1220-3. 2008
  6. pmc Targeting microRNA-122 to Treat Hepatitis C Virus Infection
    Catherine L Jopling
    School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK E mail
    Viruses 2:1382-93. 2010
  7. doi request reprint Regulation and biological function of the liver-specific miR-122
    Andrew P Lewis
    Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Biochem Soc Trans 38:1553-7. 2010
  8. doi request reprint The role of microRNAs in viral infection
    Ashley P E Roberts
    School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham NG72RD, United Kingdom
    Prog Mol Biol Transl Sci 102:101-39. 2011

Collaborators

  • Ashley P E Roberts
  • Andrew P Lewis
  • Alexander W Tarr
  • Rachel Doidge

Detail Information

Publications8

  1. pmc miR-122 activates hepatitis C virus translation by a specialized mechanism requiring particular RNA components
    Ashley P E Roberts
    Centre for Biomolecular Sciences, University of Nottingham, Nottingham, UK
    Nucleic Acids Res 39:7716-29. 2011
    ..This study provides an important insight into the requirements for the miR-122-HCV interaction, and the broader consequences of miRNAs binding to 5'-UTR sites...
  2. doi request reprint The P body protein LSm1 contributes to stimulation of hepatitis C virus translation, but not replication, by microRNA-122
    Ashley P E Roberts
    School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Nucleic Acids Res 42:1257-69. 2014
    ..Our results enhance understanding of the mechanisms by which miR-122 and LSm1 regulate HCV. ..
  3. pmc Targeting viral infection by microRNA inhibition
    Ashley P E Roberts
    School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Genome Biol 11:201. 2010
    ..An inhibitor of microRNA-122 reduces viral load in chimpanzees that are chronically infected with hepatitis C virus, suggesting that such an approach might have therapeutic potential in humans...
  4. pmc Liver-specific microRNA-122: Biogenesis and function
    Catherine Jopling
    Centre for Biomolecular Sciences University of Nottingham University Park Nottingham, UK
    RNA Biol 9:137-42. 2012
    ..This review will discuss the biogenesis and function of miR-122...
  5. doi request reprint Regulation of hepatitis C virus by microRNA-122
    Catherine L Jopling
    Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham, UK
    Biochem Soc Trans 36:1220-3. 2008
    ..The binding site requirements for miR-122 to positively regulate HCV replication provide an insight into this unusual mode of miRNA action...
  6. pmc Targeting microRNA-122 to Treat Hepatitis C Virus Infection
    Catherine L Jopling
    School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK E mail
    Viruses 2:1382-93. 2010
    ..Inhibition of miR-122 therefore presents a very attractive novel approach to treating HCV, a virus for which improved therapeutics are urgently needed...
  7. doi request reprint Regulation and biological function of the liver-specific miR-122
    Andrew P Lewis
    Centre for Biomolecular Sciences, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Biochem Soc Trans 38:1553-7. 2010
    ..In the present review, we discuss the effects of miR-122 on liver physiology and pathology. Recent evidence of pathways involved in the regulation of miR-122 expression is also considered...
  8. doi request reprint The role of microRNAs in viral infection
    Ashley P E Roberts
    School of Pharmacy, Centre for Biomolecular Sciences, University of Nottingham, Nottingham NG72RD, United Kingdom
    Prog Mol Biol Transl Sci 102:101-39. 2011
    ..In this chapter we will examine the current evidence for interplay between the miRNA pathway and viral infections in mammals...