Peter B Jones

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Comparative effectiveness of cognitive therapies delivered face-to-face or over the telephone: an observational study using propensity methods
    Geoffrey C Hammond
    National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care for Cambridgeshire and Peterborough, Cambridge, United Kingdom
    PLoS ONE 7:e42916. 2012
  2. pmc Childhood cognitive ability and adult mental health in the British 1946 birth cohort
    Stephani L Hatch
    Columbia University, New York, NY, USA
    Soc Sci Med 64:2285-96. 2007
  3. pmc Trauma exposure, PTSD and psychotic-like symptoms in post-conflict Timor Leste: an epidemiological survey
    Ian Soosay
    Department of Psychological Medicine, University of Auckland, Auckland, New Zealand
    BMC Psychiatry 12:229. 2012
  4. doi request reprint Adult mental health disorders and their age at onset
    P B Jones
    Department of Psychiatry, University of Cambridge, Cameo Early Intervention Services, Cambridgeshire and Peterborough Foundation National Health Service Trust, Herchel Smith Building for Brain and Mind Science, Cambridge CB2 0SX, UK
    Br J Psychiatry Suppl 54:s5-10. 2013
  5. ncbi request reprint Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
    Peter B Jones
    Department of Psychiatry, University of Cambridge and Cambridgeshire and Peterborough Mental Health NHS Trust, Cambridge, England
    Arch Gen Psychiatry 63:1079-87. 2006
  6. doi request reprint Neuregulin-1 genotype is associated with structural differences in the normal human brain
    Anna Barnes
    Department of Psychiatry, University of Cambridge, Box 189 Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Neuroimage 59:2057-61. 2012
  7. pmc Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children
    Jennifer H Barnett
    Department of Psychiatryand the Centre for Family Research, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Am J Psychiatry 166:909-16. 2009
  8. pmc No association of COMT (Val158Met) genotype with brain structure differences between men and women
    Anna Barnes
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    PLoS ONE 7:e33964. 2012
  9. doi request reprint Neurological abnormalities and cognitive ability in first-episode psychosis
    Paola Dazzan
    Department of Psychiatry, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 193:197-202. 2008
  10. pmc Comparison of high and low intensity contact between secondary and primary care to detect people at ultra-high risk for psychosis: study protocol for a theory-based, cluster randomized controlled trial
    Jesus Perez
    Cameo Early Intervention Services, Cambridgeshire and Peterborough NHS Foundation Trust, Ida Darwin, Fulbourn, Cambridge, UK
    Trials 14:222. 2013

Detail Information

Publications64

  1. pmc Comparative effectiveness of cognitive therapies delivered face-to-face or over the telephone: an observational study using propensity methods
    Geoffrey C Hammond
    National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care for Cambridgeshire and Peterborough, Cambridge, United Kingdom
    PLoS ONE 7:e42916. 2012
    ..To compare the clinical and cost-effectiveness of face-to-face (FTF) with over-the-telephone (OTT) delivery of low intensity cognitive behavioural therapy...
  2. pmc Childhood cognitive ability and adult mental health in the British 1946 birth cohort
    Stephani L Hatch
    Columbia University, New York, NY, USA
    Soc Sci Med 64:2285-96. 2007
    ..In addition, the underlying mechanisms responsible for the gender-specific link between childhood cognitive ability and the risk of experiencing internalising disorders in mid-adulthood warrants further consideration...
  3. pmc Trauma exposure, PTSD and psychotic-like symptoms in post-conflict Timor Leste: an epidemiological survey
    Ian Soosay
    Department of Psychological Medicine, University of Auckland, Auckland, New Zealand
    BMC Psychiatry 12:229. 2012
    ..This study aimed to assess the prevalence of psychotic-like symptoms in conflict-affected Timor Leste and to examine whether symptoms were associated with trauma and PTSD...
  4. doi request reprint Adult mental health disorders and their age at onset
    P B Jones
    Department of Psychiatry, University of Cambridge, Cameo Early Intervention Services, Cambridgeshire and Peterborough Foundation National Health Service Trust, Herchel Smith Building for Brain and Mind Science, Cambridge CB2 0SX, UK
    Br J Psychiatry Suppl 54:s5-10. 2013
    ..The paper then discusses whether this fits what is known about the developmental neurobiology of the brain and introduces the implications for mental health services...
  5. ncbi request reprint Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
    Peter B Jones
    Department of Psychiatry, University of Cambridge and Cambridgeshire and Peterborough Mental Health NHS Trust, Cambridge, England
    Arch Gen Psychiatry 63:1079-87. 2006
    ..Most evidence comes from short-term efficacy trials of symptoms...
  6. doi request reprint Neuregulin-1 genotype is associated with structural differences in the normal human brain
    Anna Barnes
    Department of Psychiatry, University of Cambridge, Box 189 Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Neuroimage 59:2057-61. 2012
    ..These results suggest that this genetic variant may mediate risk for schizophrenia, in part, through its effect on brain structure in these regions...
  7. pmc Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children
    Jennifer H Barnett
    Department of Psychiatryand the Centre for Family Research, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Am J Psychiatry 166:909-16. 2009
    ..The authors tested the hypothesis that a more informative COMT haplotype predicts normal cognitive development in a large population-based cohort of children enrolled in the Avon Longitudinal Study of Parents and Children...
  8. pmc No association of COMT (Val158Met) genotype with brain structure differences between men and women
    Anna Barnes
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    PLoS ONE 7:e33964. 2012
    ....
  9. doi request reprint Neurological abnormalities and cognitive ability in first-episode psychosis
    Paola Dazzan
    Department of Psychiatry, Box 63, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Br J Psychiatry 193:197-202. 2008
    ....
  10. pmc Comparison of high and low intensity contact between secondary and primary care to detect people at ultra-high risk for psychosis: study protocol for a theory-based, cluster randomized controlled trial
    Jesus Perez
    Cameo Early Intervention Services, Cambridgeshire and Peterborough NHS Foundation Trust, Ida Darwin, Fulbourn, Cambridge, UK
    Trials 14:222. 2013
    ..General practitioners (GPs) are usually the healthcare professionals contacted first on the help-seeking pathway of these individuals...
  11. pmc Meta-analytic approaches to determine gender differences in the age-incidence characteristics of schizophrenia and related psychoses
    Dan Jackson
    MRC Biostatistics Unit, Robinson Way, Cambridge, UK
    Int J Methods Psychiatr Res 22:36-45. 2013
    ..We describe several variations of our method, in particular those that might be used where more data is available, and provide guidance for assessing the model fit...
  12. pmc 5-HTTLPR and early childhood adversities moderate cognitive and emotional processing in adolescence
    Matthew Owens
    Development and Lifecourse Research Group, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 7:e48482. 2012
    ..Whether these two factors interact to influence cognitive and emotional processing is not known...
  13. ncbi request reprint Neighbourhood variation in the incidence of psychotic disorders in Southeast London
    James B Kirkbride
    Dept of Psychiatry, University of Cambridge, Box 189, Cambridge CB2 2QQ, UK
    Soc Psychiatry Psychiatr Epidemiol 42:438-45. 2007
    ..Urbanicity is a risk factor for schizophrenia, but it is unclear whether this risk is homogenous across urban areas...
  14. pmc Elevated morning cortisol is a stratified population-level biomarker for major depression in boys only with high depressive symptoms
    Matthew Owens
    Developmental and Lifecourse Research Group, Department of Psychiatry, University of Cambridge, Cambridge CB2 8AH, United Kingdom
    Proc Natl Acad Sci U S A 111:3638-43. 2014
    ..We suggest that the biobehavioral combination of high depressive symptoms and elevated morning cortisol is particularly hazardous for adolescent boys. ..
  15. doi request reprint Effects of modafinil on cognitive functions in first episode psychosis
    Linda Scoriels
    Department of Psychiatry, University of Cambridge, Herchel Smith Building for Brain and Mind Sciences, Cambridge Biomedical Campus, Cambridge, CB2 0SZ, UK
    Psychopharmacology (Berl) 220:249-58. 2012
    ..Modafinil is a wake-promoting drug that has been shown to improve attention, memory and executive function in the healthy population and in patients with schizophrenia...
  16. pmc The benefit of minocycline on negative symptoms in early-phase psychosis in addition to standard care - extent and mechanism (BeneMin): study protocol for a randomised controlled trial
    Danuta M Lisiecka
    Department of Psychiatry, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK
    Trials 16:71. 2015
    ..We present a protocol for a multi-centre double-blind randomised placebo-controlled clinical trial entitled The Benefit of Minocycline on Negative Symptoms of Psychosis: Extent and Mechanism (BeneMin)...
  17. pmc Psychiatric morbidity, functioning and quality of life in young people at clinical high risk for psychosis
    Christy Hui
    Department of Psychiatry, University of Cambridge, Cambridge, UK Department of Psychiatry, University of Hong Kong, Hong Kong, China
    Schizophr Res 148:175-80. 2013
    ..In this study we thoroughly examined the clinical and functional characteristics of a consecutive cohort of young people at HR for psychosis and compared them to a matched sample of healthy volunteers...
  18. doi request reprint Modafinil effects on cognition and emotion in schizophrenia and its neurochemical modulation in the brain
    Linda Scoriels
    Department of Psychiatry, University of Cambridge, UK
    Neuropharmacology 64:168-84. 2013
    ..These reviews seek to delineate the neuronal mechanisms by which modafinil affects cognitive and emotional function. This article is part of a Special Issue entitled 'Cognitive Enhancers'...
  19. ncbi request reprint Neighbourhood-level effects on psychoses: re-examining the role of context
    James B Kirkbride
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Psychol Med 37:1413-25. 2007
    ..Cross-level interactions are poorly understood. We investigated these issues using data from the Aetiology and Ethnicity in Schizophrenia and Other Psychoses (AESOP) study...
  20. pmc Adolescent self-organization predicts midlife memory in a prospective birth cohort study
    Man K Xu
    Department of Psychiatry, University of Cambridge
    Psychol Aging 28:958-68. 2013
    ..It has been suggested that interventions to improve self-organization may save a wide range of societal costs; this study also suggests that this might also benefit cognitive function in later life...
  21. doi request reprint Selective deficits in semantic verbal fluency in patients with a first affective episode with psychotic symptoms and a positive history of mania
    Eugenia Kravariti
    Department of Psychiatry, NIHR Biomedical Research Centre, Maudsley NHS Foundation Trust Institute of Psychiatry, King s College London, Box 58, De Crespigny Park, London SE5 8AF, UK
    Bipolar Disord 11:323-9. 2009
    ..We investigated neuropsychological performance in an epidemiologically derived sample of patients with a first affective episode with psychotic symptoms and a positive history of mania, compared to community controls...
  22. pmc Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR
    Jennifer H Barnett
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Am J Med Genet B Neuropsychiatr Genet 156:158-67. 2011
    ..These results suggest that assessment of multiple genes within functionally related systems may improve our understanding of the genetic basis of cognition...
  23. doi request reprint Effects of modafinil on emotional processing in first episode psychosis
    Linda Scoriels
    Department of Psychiatry, University of Cambridge, Robinson Way, Cambridge, UK
    Biol Psychiatry 69:457-64. 2011
    ..We aimed to establish whether modafinil might have a role in the adjuvant treatment of emotional impairments in the first episode of psychosis, when therapeutic endeavor is arguably most vital...
  24. pmc Incidence of schizophrenia and other psychoses in England, 1950-2009: a systematic review and meta-analyses
    James B Kirkbride
    Department of Psychiatry, Herchel Smith Building for Brain and Mind Sciences, University of Cambridge, Cambridge, United Kingdom
    PLoS ONE 7:e31660. 2012
    ....
  25. doi request reprint Clinical effectiveness and cost-effectiveness of tailored intensive liaison between primary and secondary care to identify individuals at risk of a first psychotic illness (the LEGs study): a cluster-randomised controlled trial
    Jesus Perez
    Cameo Early Intervention Services, Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK Department of Psychiatry, University of Cambridge, Cambridge, UK National Institute of Health Research Collaboration for Leadership in Applied Health Research and Care East of England CLAHRC EoE, Cambridge, UK
    Lancet Psychiatry 2:984-93. 2015
    ..We aimed to assess whether increased liaison between primary and secondary care improves the clinical effectiveness and cost-effectiveness of detection of people with, or at high risk of developing, a first psychotic illness...
  26. pmc Linking the developmental and degenerative theories of schizophrenia: association between infant development and adult cognitive decline
    Hiroyuki Kobayashi
    Department of Psychiatry, University of Cambridge, Cambridge, UK Department of Neuropsychiatry, School of Medicine, Toho University, Tokyo, Japan
    Schizophr Bull 40:1319-27. 2014
    ....
  27. ncbi request reprint A longitudinal typology of symptoms of depression and anxiety over the life course
    Ian Colman
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Biol Psychiatry 62:1265-71. 2007
    ..The objective of this study was to identify a novel typology of symptoms of depression and anxiety over the life course and examine its neurodevelopmental antecedents in an epidemiological sample...
  28. pmc Childhood cognitive function and adult psychopathology: associations with psychotic and non-psychotic symptoms in the general population
    Jennifer H Barnett
    Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
    Br J Psychiatry 201:124-30. 2012
    ..Lower cognitive ability in childhood is associated with increased risk of future schizophrenia, but its relationship with adult psychotic-like experiences and other psychopathology is less understood...
  29. pmc Depressive symptoms during adolescence: comparison between epidemiological and high risk sampling
    Michelle C St Clair
    Department of Psychiatry, Developmental and Lifecourse Research Group, University of Cambridge, Douglas House, 18b Trumpington Road, Cambridge, CB2 8AH, UK
    Soc Psychiatry Psychiatr Epidemiol 47:1333-41. 2012
    ..This study compared depressive symptoms across the two sampling methods to test this possibility...
  30. pmc The prevention of schizophrenia--what can we learn from eco-epidemiology?
    James B Kirkbride
    Department of Psychiatry, Herchel Smith Building for Brain and Mind Sciences, University of Cambridge, Forvie Site, Robinson Way, Cambridge, UK
    Schizophr Bull 37:262-71. 2011
    ..We conclude by speculating on the forms effective strategies might take...
  31. doi request reprint Longitudinal regional brain volume loss in schizophrenia: Relationship to antipsychotic medication and change in social function
    Joyce Y Guo
    Department of Psychiatry, Cambridge Biomedical Campus, University of Cambridge, Box 189 CB2 0QQ, United Kingdom Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 0SZ, United Kingdom
    Schizophr Res 168:297-304. 2015
    ..We investigated progressive regional brain reductions in schizophrenia and correlations with potential mediators...
  32. doi request reprint Use of the Theory of Planned Behaviour to assess factors influencing the identification of students at clinical high-risk for psychosis in 16+ Education
    Debra A Russo
    CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, Block 7, Ida Darwin Site, Fulbourn Hospital, Fulbourn, Cambridge, CB21 5EE, UK
    BMC Health Serv Res 15:411. 2015
    ..This study employed the Theory of Planned Behaviour (TPB) to identify and measure factors that influence identification of students at high-risk (HR) of developing psychosis in 16+ educational institutions...
  33. pmc Ten-Year Outcomes of First-Episode Psychoses in the MRC ÆSOP-10 Study
    Camice J Revier
    Department of Psychiatry, University of Cambridge, National Institute for Health Research NIHR Cambridge Biomedical Research Centre and NIHR Collaboration for Leadership in Applied Health Research and Care, Cambridge, UK Centre for Epidemiology and Public Health, Health Service and Population Research Department, Institute of Psychiatry, King s College, London, UK Department of Psychiatry and Psychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands Department of Psychological Medicine, Institute of Psychiatry, King s College, London, UK Department of Psychiatry, Trinity College, Dublin, Ireland NIHR Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King s College, London, UK Psychosis Studies Department, Institute of Psychiatry, King s College, London, UK Division of Psychiatry and Applied Psychology, University of Nottingham, Nottingham, UK Department of Nursing and Midwifery, University of Dundee, Dundee, UK Centre for Economics of Mental and Physical Health, Health Service and Population Research Department, Institute of Psychiatry, King s College, London, UK Department of Psychology, Institute of Psychiatry, Psychology and Neuroscience at King s College, London, UK Institute of Psychiatry, Psychology and Neuroscience at King s College, London
    J Nerv Ment Dis 203:379-86. 2015
    ..These results suggest that researchers, clinicians and those affected by psychosis should countenance a much more optimistic view of symptomatic outcome than was assumed when these conditions were first described. ..
  34. pmc A quantitative meta-analysis of population-based studies of premorbid intelligence and schizophrenia
    Golam M Khandaker
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Schizophr Res 132:220-7. 2011
    ....
  35. pmc Substance use in people at clinical high-risk for psychosis
    Debra A Russo
    CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK
    BMC Psychiatry 14:361. 2014
    ....
  36. doi request reprint Exercise and depressive symptoms in adolescents: a longitudinal cohort study
    Umar Toseeb
    Development and Lifecourse Research Group, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    JAMA Pediatr 168:1093-100. 2014
    ..Physical activity (PA) may have a positive effect on depressed mood. However, whether it can act as a protective factor against developing depressive symptoms in adolescence is largely unknown...
  37. pmc Childhood Epstein-Barr Virus infection and subsequent risk of psychotic experiences in adolescence: a population-based prospective serological study
    Golam M Khandaker
    Department of Psychiatry, University of Cambridge, UK Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK Centre for Mental Health, Addiction and Suicide Research, School of Social and Community Medicine, University of Bristol, UK Electronic address
    Schizophr Res 158:19-24. 2014
    ..We report a longitudinal serological study of early-life EBV infection, childhood IQ, and subsequent risk of psychotic experiences (PE) in adolescence...
  38. pmc Infant developmental milestones and subsequent cognitive function
    Graham K Murray
    Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    Ann Neurol 62:128-36. 2007
    ..We hypothesized that earlier attainment of developmental milestones would be associated with better subsequent intellectual performance throughout the range of abilities, rather than confined to extremes...
  39. pmc A population-based prospective birth cohort study of childhood neurocognitive and psychological functioning in healthy survivors of early life meningitis
    Golam M Khandaker
    Department of Psychiatry, University of Cambridge, Cambridge, UK National Institute for Health Research Biomedical Research Centre, Cambridge, UK Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK Electronic address
    Ann Epidemiol 25:236-42. 2015
    ..To determine neurocognitive, educational, and psychological functioning during childhood and early adolescence among survivors of early life meningitis who are apparently healthy...
  40. ncbi request reprint Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children
    Jennifer H Barnett
    University of Cambridge, Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Am J Psychiatry 164:142-9. 2007
    ..This polymorphism affects cognitive function in healthy adults and may contribute to risk for schizophrenia...
  41. pmc Improvement and decline of cognitive function in schizophrenia over one year: a longitudinal investigation using latent growth modelling
    Jennifer H Barnett
    University of Cambridge Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
    BMC Psychiatry 7:16. 2007
    ..Long-term follow-up studies of people with schizophrenia report stability of cognitive performance; less is known about any shorter-term changes in cognitive function...
  42. pmc Trauma history characteristics associated with mental states at clinical high risk for psychosis
    Debra A Russo
    CAMEO Early Intervention in Psychosis Service, Cambridgeshire and Peterborough NHS Foundation Trust, UK Department of Psychiatry, University of Cambridge, Cambridge, UK
    Psychiatry Res 220:237-44. 2014
    ....
  43. doi request reprint The impact of neuroscience on society: cognitive enhancement in neuropsychiatric disorders and in healthy people
    Barbara J Sahakian
    Department of Psychiatry, University of Cambridge, Herchel Smith Building for Brain and Mind Sciences, Forvie Site, Robinson Way, Cambridge CB2 0SZ, UK MRC Wellcome Trust Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge CB2 3EB, UK
    Philos Trans R Soc Lond B Biol Sci 370:20140214. 2015
    ..g. pharmacological, exercise, lifelong learning) are acceptable and for which groups (e.g. military, doctors) under what conditions (e.g. war, shift work) and by what methods we would wish to improve and flourish. ..
  44. ncbi request reprint Forty-year psychiatric outcomes following assessment for internalizing disorder in adolescence
    Ian Colman
    Department of Psychiatry, University of Cambridge, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Am J Psychiatry 164:126-33. 2007
    ..The aim of this study was to define the long-term psychiatric outcomes of adolescent internalizing disorder in the general population, using data collected over 40 years from a national birth cohort...
  45. ncbi request reprint Substance use in a population-based clinic sample of people with first-episode psychosis
    Jennifer H Barnett
    Department of Psychiatry, Box 189, University of Cambridge, UK
    Br J Psychiatry 190:515-20. 2007
    ..Substance use is implicated in the cause and course of psychosis...
  46. doi request reprint The benefit of minocycline on negative symptoms in early-phase psychosis in addition to standard care - extent and mechanism (BeneMin): study protocol for a randomised controlled trial
    Danuta M Lisiecka
    Department of Psychiatry, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK
    Trials 16:580. 2015
    ..We present a protocol for a multi-centre double-blind randomised placebo-controlled clinical trial entitled The Benefit of Minocycline on Negative Symptoms of Psychosis: Extent and Mechanism (BeneMin)...
  47. pmc Association of serum interleukin 6 and C-reactive protein in childhood with depression and psychosis in young adult life: a population-based longitudinal study
    Golam M Khandaker
    Department of Psychiatry, University of Cambridge, Cambridge, England2National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, England3Collaboration for Leadership in Applied Health Research and Care, East of England, Cambri
    JAMA Psychiatry 71:1121-8. 2014
    ....
  48. doi request reprint Multilevel ordinal factor analysis of the positive and negative syndrome scale (PANSS)
    Jan Stochl
    Department of Psychiatry, University of Cambridge, Cambridge, UK Cameo Early Intervention Services, Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK
    Int J Methods Psychiatr Res 23:25-35. 2014
    ..Our modeling results support the pentagonal PANSS model first proposed by White et al. (1997). Copyright © 2014 John Wiley & Sons, Ltd. ..
  49. pmc Profiles of family-focused adverse experiences through childhood and early adolescence: the ROOTS project a community investigation of adolescent mental health
    Valerie J Dunn
    Developmental and Life course Research Group, Department of Psychiatry, University of Cambridge, Cambridge, UK
    BMC Psychiatry 11:109. 2011
    ..Adverse family experiences in early life are associated with subsequent psychopathology. This study adds to the growing body of work exploring the nature and associations between adverse experiences over the childhood years...
  50. pmc Incentive motivation in first-episode psychosis: a behavioural study
    Graham K Murray
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, UK
    BMC Psychiatry 8:34. 2008
    ..It has been proposed that there are abnormalities in incentive motivational processing in psychosis, possibly secondary to subcortical dopamine abnormalities, but few empirical studies have addressed this issue...
  51. pmc Childhood infection and adult schizophrenia: a meta-analysis of population-based studies
    Golam M Khandaker
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Schizophr Res 139:161-8. 2012
    ..To determine whether exposures to infectious illness during childhood involving the CNS or elsewhere is associated with adult schizophrenia or other psychoses...
  52. doi request reprint Inflammation and immunity in schizophrenia: implications for pathophysiology and treatment
    Golam M Khandaker
    Department of Psychiatry, University of Cambridge, Cambridge, UK National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge, UK Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK Electronic address
    Lancet Psychiatry 2:258-70. 2015
    ..We discuss potential mechanisms and therapeutic implications of these findings, including studies of anti-inflammatory drugs in schizophrenia, describe areas for development, and offer testable hypotheses for future investigations. ..
  53. pmc Fronto-cerebellar systems are associated with infant motor and adult executive functions in healthy adults but not in schizophrenia
    Khanum Ridler
    Brain Mapping Unit, Department of Psychiatry, Addenbrooke s Hospital, University of Cambridge, Cambridge CB2 2QQ, United Kingdom
    Proc Natl Acad Sci U S A 103:15651-6. 2006
    ..Disruption of this anatomical system may underlie both the early developmental and adult cognitive abnormalities in schizophrenia...
  54. doi request reprint Brain structure in different psychosis risk groups in the Northern Finland 1986 birth cohort
    Andres Roman-Urrestarazu
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Schizophr Res 153:143-9. 2014
    ..These findings are consistent with an evolving pattern of cerebellar deficits in psychosis risk with the most pronounced deficits in those at highest risk of psychosis. ..
  55. pmc A population-based study of atopic disorders and inflammatory markers in childhood before psychotic experiences in adolescence
    Golam M Khandaker
    Department of Psychiatry, University of Cambridge, UK Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK Centre for Mental Health, Addiction and Suicide Research, School of Social and Community Medicine, University of Bristol, UK Electronic address
    Schizophr Res 152:139-45. 2014
    ....
  56. pmc Mokken scale analysis of mental health and well-being questionnaire item responses: a non-parametric IRT method in empirical research for applied health researchers
    Jan Stochl
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    BMC Med Res Methodol 12:74. 2012
    ..abstract:..
  57. doi request reprint Use of the theory of planned behaviour to assess factors influencing the identification of individuals at ultra-high risk for psychosis in primary care
    Debra A Russo
    Cameo Early Intervention Services, Cambridgeshire and Peterborough NHS Foundation Trust, UK
    Early Interv Psychiatry 6:265-75. 2012
    ..It will inform the subsequent design of educational interventions to help general practitioners (GPs; primary care physicians) detect these individuals...
  58. doi request reprint The ROOTS study: a 10-year review of findings on adolescent depression, and recommendations for future longitudinal research
    Gemma Lewis
    Department of Psychiatry, University of Cambridge, Douglas House, 18b Trumpington Road, Cambridge, CB2 8AH, UK
    Soc Psychiatry Psychiatr Epidemiol 51:161-70. 2016
    ..To do this, we discuss relevant findings from the ROOTS study, and review its strengths and limitations...
  59. doi request reprint The brain structural disposition to social interaction
    Maël Lebreton
    Brain Mapping Unit, University of Cambridge, Cambridge, UK
    Eur J Neurosci 29:2247-52. 2009
    ..These findings provide evidence for a brain structural disposition to social interaction, and that sensitivity to social reward shares a common neural basis with systems for processing primary reward information...
  60. ncbi request reprint Three decades of antidepressant, anxiolytic and hypnotic use in a national population birth cohort
    Ian Colman
    Department of Psychiatry, University of Cambridge, UK
    Br J Psychiatry 189:156-60. 2006
    ..Psychotropic medication use is common and increasing. Use of such drugs at the individual level over long periods has not been reported...
  61. doi request reprint Cannabis use is associated with increased CCL11 plasma levels in young healthy volunteers
    Emilio Fernandez-Egea
    Department of Psychiatry, University of Cambridge, Cambridge, UK Cambridgeshire and Peterborough NHS Foundation Trust, Cambridge, UK Behavioural and Clinical Neuroscience Institute BCNI, University of Cambridge, Cambridge, UK Electronic address
    Prog Neuropsychopharmacol Biol Psychiatry 46:25-8. 2013
    ..These results suggest that cannabis use increases CCL11 plasma levels and the effects are reversible when cannabis use ceases. ..
  62. pmc Intrinsic curvature: a marker of millimeter-scale tangential cortico-cortical connectivity?
    Lisa Ronan
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, UK
    Int J Neural Syst 21:351-66. 2011
    ..Thus, the degree of cortical intrinsic curvature may have implications for short-range connectivity...
  63. ncbi request reprint Psychotic symptoms in young people without psychotic illness: mechanisms and meaning
    Graham K Murray
    Department of Psychiatry, University of Cambridge, Box 189 Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    Br J Psychiatry 201:4-6. 2012
    ..Clinicians should be aware that psychotic symptoms in young people are more often associated with common mental disorders such as depression and anxiety than with severe psychotic illness...
  64. ncbi request reprint Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study
    James B Kirkbride
    Department of Psychiatry, University of Cambridge, Cambridge, England
    Arch Gen Psychiatry 63:250-8. 2006
    ..Convention suggests uniformity of incidence of schizophrenia and other psychoses; variation would have implications for their causes and biological characteristics...