I Jones

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. ncbi Molecular genetic studies of bipolar disorder and puerperal psychosis at two polymorphisms in the estrogen receptor alpha gene (ESR 1)
    I Jones
    Division of Neuroscience, University of Birmingham, Birmingham B15 2QZ, United Kingdom
    Am J Med Genet 96:850-3. 2000
  2. ncbi Do puerperal psychotic episodes identify a more familial subtype of bipolar disorder? Results of a family history study
    Ian Jones
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
    Psychiatr Genet 12:177-80. 2002
  3. ncbi Attitudes towards future testing for bipolar disorder susceptibility genes: a preliminary investigation
    Ian Jones
    Division of Neuroscience, Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, UK
    J Affect Disord 71:189-93. 2002
  4. ncbi Triplet repeats and bipolar disorder
    Ian Jones
    Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, United Kingdom
    Curr Psychiatry Rep 4:134-40. 2002
  5. ncbi Molecular genetic approaches to puerperal psychosis
    I Jones
    Division of Neurosciences, Department of Psychiatry, University of Birmingham, Birmingham B15 2QZ, UK
    Prog Brain Res 133:321-31. 2001
  6. ncbi Familiality of the puerperal trigger in bipolar disorder: results of a family study
    I Jones
    Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, UK
    Am J Psychiatry 158:913-7. 2001
  7. ncbi No association between two polymorphisms at the 5HT2A gene and bipolar affective puerperal psychosis
    E Robertson
    Department of Psychiatry, Division of Neuroscience, Queen Elizabeth Psychiatric Hospital, University of Birmingham, Edgbaston, Birmingham, UK
    Acta Psychiatr Scand 108:387-91. 2003
  8. ncbi Tumour necrosis factor alpha and bipolar affective puerperal psychosis
    F Middle
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, UK
    Psychiatr Genet 10:195-8. 2000
  9. ncbi The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report
    P Bennett
    Molecular Psychiatry Group, Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Edgbaston, Birmingham, B15 2QZ, UK
    Mol Psychiatry 7:189-200. 2002
  10. ncbi Allelic variation of a BalI polymorphism in the DRD3 gene does not influence susceptibility to bipolar disorder: results of analysis and meta-analysis
    G Elvidge
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, England
    Am J Med Genet 105:307-11. 2001

Detail Information

Publications50

  1. ncbi Molecular genetic studies of bipolar disorder and puerperal psychosis at two polymorphisms in the estrogen receptor alpha gene (ESR 1)
    I Jones
    Division of Neuroscience, University of Birmingham, Birmingham B15 2QZ, United Kingdom
    Am J Med Genet 96:850-3. 2000
    ..Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:850-853, 2000...
  2. ncbi Do puerperal psychotic episodes identify a more familial subtype of bipolar disorder? Results of a family history study
    Ian Jones
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
    Psychiatr Genet 12:177-80. 2002
    ..0077). Despite relatively small numbers, this study provides evidence to support the hypothesis that puerperal episodes identify a more familial subtype of bipolar disorder...
  3. ncbi Attitudes towards future testing for bipolar disorder susceptibility genes: a preliminary investigation
    Ian Jones
    Division of Neuroscience, Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, UK
    J Affect Disord 71:189-93. 2002
    ..Psychiatrists, who will have to administer such tests, appear significantly more cautious...
  4. ncbi Triplet repeats and bipolar disorder
    Ian Jones
    Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, United Kingdom
    Curr Psychiatry Rep 4:134-40. 2002
    ..It is likely that the controversy surrounding anticipation and the existence of triplet repeats will only finally be resolved with the demonstration of such a mutation in the aetiology of bipolar disorder...
  5. ncbi Molecular genetic approaches to puerperal psychosis
    I Jones
    Division of Neurosciences, Department of Psychiatry, University of Birmingham, Birmingham B15 2QZ, UK
    Prog Brain Res 133:321-31. 2001
    ..Elucidating the pathophysiological basis of this disorder will lead to better prevention and treatment and, it is anticipated, inform research on affective disorders more generally...
  6. ncbi Familiality of the puerperal trigger in bipolar disorder: results of a family study
    I Jones
    Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, UK
    Am J Psychiatry 158:913-7. 2001
    ..The single large study that used direct interview of relatives suggested that familial factors play a role in vulnerability to puerperal triggering itself. The authors' goal was to test this hypothesis further...
  7. ncbi No association between two polymorphisms at the 5HT2A gene and bipolar affective puerperal psychosis
    E Robertson
    Department of Psychiatry, Division of Neuroscience, Queen Elizabeth Psychiatric Hospital, University of Birmingham, Edgbaston, Birmingham, UK
    Acta Psychiatr Scand 108:387-91. 2003
    ..To examine whether variation at two common polymorphisms, T102C and -1438AG, of the serotonin 2A gene (5HT2A) are involved in the puerperal triggering mechanism of bipolar affective puerperal psychosis...
  8. ncbi Tumour necrosis factor alpha and bipolar affective puerperal psychosis
    F Middle
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, UK
    Psychiatr Genet 10:195-8. 2000
    ..However, variation at other polymorphisms within TNFalpha or in other oestrogen-regulated genes involved in immune function remain interesting candidates for study in post-partum mood disorders...
  9. ncbi The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report
    P Bennett
    Molecular Psychiatry Group, Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Edgbaston, Birmingham, B15 2QZ, UK
    Mol Psychiatry 7:189-200. 2002
    ..54). Overall the highest MLS was 1.70 on chromosome 2 at marker D2S125, under the broadest diagnostic model...
  10. ncbi Allelic variation of a BalI polymorphism in the DRD3 gene does not influence susceptibility to bipolar disorder: results of analysis and meta-analysis
    G Elvidge
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, England
    Am J Med Genet 105:307-11. 2001
    ..It remains possible, however, that other sequence variations within the DRD3 gene could play a role...
  11. ncbi Evidence for familial cosegregation of major affective disorder and genetic markers flanking the gene for Darier's disease
    I Jones
    Department of Psychiatry, Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Mindelsohn Way, Edgbaston, Birmingham B15 2QZ, UK
    Mol Psychiatry 7:424-7. 2002
    ..58). The family provides strong evidence against the Darier-causing mutation itself playing a major role in affective disorder but strongly supports the existence of a bipolar disorder susceptibility gene in the Darier region...
  12. ncbi Candidate gene studies of bipolar disorder
    I Jones
    Division of Neuroscience, University of Birmingham, UK
    Ann Med 33:248-56. 2001
    ..As susceptibility genes are found and knowledge of aetiology advanced it is likely that many more candidate genes in novel biological systems will attract attention...
  13. doi Early postpartum symptoms in puerperal psychosis
    J Heron
    Department of Primary Care and General Practice, University of Birmingham, Birmingham, UK
    BJOG 115:348-53. 2008
    ..To examine the nature of the earliest reported symptoms in women who develop a bipolar affective puerperal psychosis (PP)...
  14. ncbi No 'latent period' in the onset of bipolar affective puerperal psychosis
    J Heron
    Department of Psychiatry, University of Birmingham, Birmingham, UK
    Arch Womens Ment Health 10:79-81. 2007
    ..We find no evidence of a latent period. Over 50% of symptom onsets occur on days 1-3, with over 22% occurring on the first postpartum day...
  15. ncbi Molecular genetics of bipolar disorder
    N Craddock
    Division of Neuroscience, University of Birmingham, UK
    Br J Psychiatry Suppl 41:s128-33. 2001
    ..Recent advances in molecular genetics have made it possible to identify these susceptibility genes...
  16. ncbi Self-reported schizotypy and bipolar disorder: demonstration of a lack of specificity of the Kings Schizotypy Questionnaire
    J Heron
    Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, UK
    Schizophr Res 65:153-8. 2003
    ..We conclude that elevated self-reported schizotypy as measured by the KSQ is not specific to schizophrenia, and may be associated with functional psychosis in general...
  17. doi Measuring hypomania in the postpartum: a comparison of the Highs Scale and the Altman Mania Rating Scale
    S Smith
    School of Medicine, University of Birmingham, Birmingham, UK
    Arch Womens Ment Health 12:323-7. 2009
    ..Mania scales developed in bipolar disorder populations must be specifically validated for postpartum use...
  18. ncbi Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16
    Ian Jones
    Department of Psychological Medicine, Henry Wellcome Building, Wales School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN UK
    Am J Psychiatry 164:1099-104. 2007
    ..The authors conducted a search by systematic whole genome linkage scan for loci influencing vulnerability to bipolar affective puerperal psychosis...
  19. ncbi Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
    Marian L Hamshere
    Department of Psychological Medicine, School of Medicine, Cardiff University, Wales
    Arch Gen Psychiatry 62:1081-8. 2005
    ..However, twin data suggest that, in addition to genes with specificity for these phenotypes, there exist genes that simultaneously influence susceptibility to schizophrenia, bipolar disorder, and schizoaffective disorder...
  20. ncbi Cognitive style in bipolar disorder
    Lisa Jones
    Department of Psychiatry, Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham B15 2QZ, UK
    Br J Psychiatry 187:431-7. 2005
    ..Abnormalities of cognitive style in bipolar disorder are of both clinical and theoretical importance...
  21. doi Incidence of hospitalization for postpartum psychotic and bipolar episodes
    Ian Jones
    Arch Gen Psychiatry 65:356. 2008
  22. ncbi Bipolar disorder and polymorphisms in the dysbindin gene (DTNBP1)
    Rachel Raybould
    Department of Psychological Medicine, Wales College of Medicine, Cardiff University, Cardiff, Wales, UK
    Biol Psychiatry 57:696-701. 2005
    ..We previously reported that variation at a specific 3-locus haplotype influences susceptibility to schizophrenia in a large United Kingdom (UK) Caucasian case-control sample...
  23. ncbi Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder
    Nigel M Williams
    Department of Psychological Medicine and Biostatistics and Bioinformatics Unit, Wales School of Medicine, Cardiff University
    Arch Gen Psychiatry 63:366-73. 2006
    ..Variation at the DAOA/G30 locus has been described to be associated with both schizophrenia and bipolar disorder, but there is little consistency between studies of the tested polymorphisms or variants showing association...
  24. ncbi Familiality of postpartum depression in unipolar disorder: results of a family study
    Liz Forty
    Henry Wellcome Building for Biomedical Research, Wales School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK
    Am J Psychiatry 163:1549-53. 2006
    ..The authors here examine whether vulnerability to postpartum triggering of depressive episodes aggregates in families and assess how this aggregation varies with the definition of postpartum onset...
  25. ncbi Clinical presentation of postnatal and non-postnatal depressive episodes
    Carly Cooper
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
    Psychol Med 37:1273-80. 2007
    ..We have undertaken within- and between-individual comparisons of the clinical presentation of postnatal (PN) and non-postnatal (NPN) depressive episodes in women with recurrent depression...
  26. ncbi Searching for the puerperal trigger: molecular genetic studies of bipolar affective puerperal psychosis
    Ian Jones
    Perinatal Psychiatry, Department of Psychological Medicine, The Henry Wellcome Building for Biomedical Research in Wales, Neuropsychiatric Genetics Group, Cardiff University, Cardiff, United Kingdom
    Psychopharmacol Bull 40:115-28. 2007
    ..We are undertaking association studies in women with postpartum psychosis at a number of candidate genes of interest in BP disorder with an emphasis on those for which the expression is influenced by steroid hormones...
  27. doi Clinical differences between bipolar and unipolar depression
    Liz Forty
    Department of Psychological Medicine, Wales School of Medicine, Cardiff University, Heath Park, Cardiff, UK
    Br J Psychiatry 192:388-9. 2008
    ..Such features should alert a clinician to a possible bipolar course. This is important because optimal management is not the same for bipolar and unipolar depression...
  28. ncbi Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder
    Elaine K Green
    Department of Psychological Medicine and Biostatics and Bioinformatics Unit, University of Wales College of Medicine, Cardiff
    Arch Gen Psychiatry 62:642-8. 2005
    ..The most consistent finding has been that one particular haplotype (the "core" haplotype) is overrepresented in cases compared with control subjects...
  29. ncbi Bipolar disorder and childbirth: the importance of recognising risk
    Ian Jones
    Br J Psychiatry 186:453-4. 2005
  30. ncbi Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK
    Elaine K Green
    Department of Psychological Medicine, Henry Wellcome Building, Wales College of Medicine, Cardiff University, Heath Park, Cardiff CF4 4XN, Wales, UK
    Br J Psychiatry 188:21-5. 2006
    ..Three family-based studies have shown association of the common Valine (Val) allele of the Val66Met polymorphism of the BDNF gene with susceptibility to bipolar disorder...
  31. ncbi Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin
    Sven Cichon
    Nat Genet 36:783-4; author reply 784-5. 2004
  32. pmc The Depression Network (DeNT) Study: methodology and sociodemographic characteristics of the first 470 affected sibling pairs from a large multi-site linkage genetic study
    Anne Farmer
    Medical Research Council Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, London, UK
    BMC Psychiatry 4:42. 2004
    ..This study presents the method and socio-demographic details of the first 470 affected sibling pairs recruited from 8 different sites in Europe and the United States of America...
  33. ncbi Localization of bipolar susceptibility locus by molecular genetic analysis of the chromosome 12q23-q24 region in two pedigrees with bipolar disorder and Darier's disease
    Elaine Green
    Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff, Wales, UK
    Am J Psychiatry 162:35-42. 2005
    ..Here molecular genetic analyses aimed at localizing and identifying the susceptibility gene in this region are reported...
  34. ncbi Risk of puerperal and non-puerperal recurrence of illness following bipolar affective puerperal (post-partum) psychosis
    Emma Robertson
    Neuropsychiatric Genetics Unit, Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, Wales, UK
    Br J Psychiatry 186:258-9. 2005
    ..A history of bipolar episodes prior to the puerperal psychosis did not predict risk following subsequent pregnancies, but positive family history of mental illness predicted shorter time to non-puerperal relapse...
  35. ncbi Variation in the coding sequence and flanking splice junctions of the estrogen receptor alpha (ERalpha) gene does not play an important role in genetic susceptibility to bipolar disorder or bipolar affective puerperal psychosis
    Fiona Middle
    Division of Neuroscience, Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
    Am J Med Genet B Neuropsychiatr Genet 118:72-5. 2003
    ..We conclude that variation in the coding sequence and flanking splice junctions of the ERalpha gene does not play an important pathogenic role in the majority of cases of Bipolar Disorder or Bipolar Affective Puerperal Psychosis...
  36. doi Medical disorders in people with recurrent depression
    Anne Farmer
    Medical Research Council, Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, De Crespigny Park, London, UK
    Br J Psychiatry 192:351-5. 2008
    ..Few studies have examined the rates of physical disorders in those with recurrent depression...
  37. doi Clinical questions and uncertainty--prolactin measurement in patients with schizophrenia and bipolar disorder
    James Walters
    Department of Psychological Medicine, Cardiff University, Heath Park, Cardiff, UK
    J Psychopharmacol 22:82-9. 2008
    ..We will identify the areas of uncertainty that remain for clinicians and consider the practical questions that future research should address...
  38. ncbi Coronary care units should care for all at-risk cardiac patients
    Ian Jones
    School of Nursing, University of Salford
    Prof Nurse 18:287. 2003
    ..Coronary care units have transformed the treatment of many patients whose lives are at risk. But many others who should be in these wards are still treated elsewhere...
  39. ncbi Differences in depressive symptom profile between males and females
    Daniel J Smith
    Department of Psychological Medicine, School of Medicine, Cardiff University, Heath Park, Cardiff, Wales, CF10 3XQ, UK
    J Affect Disord 108:279-84. 2008
    ..Here we compare the clinical profile of major depression for men and women from a sample of almost 600 well-characterized individuals with recurrent major depressive disorder (MDD)...
  40. doi Management of postnatal depression
    Charles Musters
    East London NHS Foundation Trust, City and Hackney Centre for Mental Health, London E9 6SR
    BMJ 337:a736. 2008
  41. ncbi Anticipation and repeat expansion in bipolar disorder
    MICHAEL O'DONOVAN
    Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff, UK
    Am J Med Genet C Semin Med Genet 123:10-7. 2003
    ..No pathogenic triplet repeat has yet been unambiguously implicated...
  42. ncbi Acute coronary syndromes: identification and patient care
    Ian Jones
    School of Nursing, University of Salford
    Prof Nurse 18:289-92. 2003
    ..These three conditions share a very similar pathology, although treatments differ. This paper examines the pathophysiology, identification, classification and management of these conditions...
  43. ncbi Providers' beliefs, attitudes, and behaviors before implementing a computerized pneumococcal vaccination reminder
    Judith W Dexheimer
    Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA
    Acad Emerg Med 13:1312-8. 2006
    ..The emergency department (ED) has been recommended as a suitable setting for offering pneumococcal vaccination; however, implementations of ED vaccination programs remain scarce...
  44. ncbi Associations among postpartum depression, eating disorders, and perfectionism in a population-based sample of adult women
    Suzanne E Mazzeo
    Department of Psychology, Virginia Commonwealth University, Richmond, Virginia 23284 2018, USA
    Int J Eat Disord 39:202-11. 2006
    ..The current study investigated associations among eating disorders, depressive symptoms during pregnancy and postpartum, and perfectionism in a population-based sample of women...
  45. ncbi Obstetric variables associated with bipolar affective puerperal psychosis
    Emma Robertson Blackmore
    Neuropsychiatric Genetics Unit, Department of Psychological Medicine, University of Cardiff, Heath Park, Cardiff CF14 4XN, Wales, UK
    Br J Psychiatry 188:32-6. 2006
    ..These include: (a) primiparity, (b) pregnancy complications, (c) delivery complications, (d) Caesarean section, (e) female baby and (f) shorter gestation period...
  46. pmc The Bipolar Affective Disorder Dimension Scale (BADDS)--a dimensional scale for rating lifetime psychopathology in bipolar spectrum disorders
    Nick Craddock
    Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
    BMC Psychiatry 4:19. 2004
    ..This latter limitation is particularly pertinent in the context of the increasing evidence for the existence of a broader bipolar spectrum than has been acknowledged within existing classifications...
  47. pmc Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q
    Matthew B McQueen
    Harvard School of Public Health, Department of Epidemiology, Boston, MA 02115, USA
    Am J Hum Genet 77:582-95. 2005
    ..Our results establish genomewide significant linkage to BP on chromosomes 6q and 8q, which provides solid information to guide future gene-finding efforts that rely on fine-mapping and association approaches...
  48. ncbi Postnatal euphoria: are 'the highs' an indicator of bipolarity?
    Jessica Heron
    Department of Psychiatry, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, UK
    Bipolar Disord 7:103-10. 2005
    ..This paper critically reviews the literature on milder forms of high mood occurring in the puerperium and discusses the potential clinical and research significance of 'the highs'...
  49. ncbi Antibiotic concentrations in serum and wound fluid after local gentamicin or intravenous dicloxacillin prophylaxis in cardiac surgery
    Orjan Friberg
    Department of Cardiothoracic Surgery, Orebro University Hospital, Orebro, Sweden
    Scand J Infect Dis 35:251-4. 2003
    ..Locally administered gentamicin resulted in high local concentrations, potentially effective against agents normally considered resistant...
  50. pmc The genetics of anorexia nervosa collaborative study: methods and sample description
    Walter H Kaye
    Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania
    Int J Eat Disord 41:289-300. 2008
    ..Supported by National Institute of Mental Health (NIMH), this 12-site international collaboration seeks to identify genetic variants that affect risk for anorexia nervosa (AN)...