Research Topics
| E A JonesSummaryAffiliation: University of Newcastle Country: UK Publications
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Detail Information
Publications
JAGGED1 expression in human embryos: correlation with the Alagille syndrome phenotypeE A Jones
Institute of Human Genetics, School of Biochemistry and Genetics, Ground Floor, Ridley Building, University of Newcastle upon Tyne, Claremont Place, Newcastle upon Tyne NE1 7RU, UK
J Med Genet 37:658-62. 2000..We conclude that JAG1 is expressed in the structures affected in Alagille syndrome, such as the pulmonary artery, anterior chamber of the eye, and face...
Differences between human and mouse alpha-fetoprotein expression during early developmentE A Jones
Institute of Human Genetics, School of Biochemistry and Genetics, University of Newcastle upon Tyne, UK
J Anat 198:555-9. 2001..It is interesting that AFP is expressed by tumours such as primitive gastrointestinal, renal cell and pancreatic tumours as well as those of hepatocyte origin. This distribution reflects the sites of AFP expression during development...
Hepatic differentiation of murine embryonic stem cellsElizabeth A Jones
Institute of Human Genetics, International Centre for Life, Central Parkway, Newcastle upon Tyne, NE1 3BZ, United Kingdom
Exp Cell Res 272:15-22. 2002..In addition, human ES cells have recently been derived and it has been proposed that they may provide a source of differentiated cell types for cell replacement therapies in the treatment of a variety of diseases...
The lmx1b gene is pivotal in glomus development in Xenopus laevisCaroline E Haldin
Department of Biological Sciences, Warwick University, Coventry, CV4 7AL, UK
Dev Biol 322:74-85. 2008....
X-epilectin: a novel epidermal fucolectin regulated by BMP signallingKarine Masse
Molecular Physiology, Department of Biological Sciences, Warwick University, Coventry, UK
Int J Dev Biol 48:1119-29. 2004..We also show that X-epilectin expression is down-regulated by Noggin and tBR and that this effect is inhibited by BMP4 over-expression, suggesting X-epilectin expression is mediated by the BMP signalling pathway...
Isolation and growth factor inducibility of the Xenopus laevis Lmx1b geneCaroline E Haldin
Cell and Molecular Development Group, Department of Biological Sciences, Warwick University, Coventry, UK
Int J Dev Biol 47:253-62. 2003..Xlmx1b was found to be upregulated by activin A and RA inhibited this upregulation in a concentration dependant manner. In contrast, bFGF had no effect on the regulation of Xlmx1b...
A functional screen for genes involved in Xenopus pronephros developmentJun ichi Kyuno
Department of Biological Sciences, Warwick University, Gibbet Hill Road, Coventry CV4 7AL, UK
Mech Dev 125:571-86. 2008..These results suggest that our strategy to identify novel genes involved in pronephros development was highly successful, and that this strategy is effective for the identification of novel genes involved in late developmental events...
Purine-mediated signalling triggers eye developmentKarine Masse
Department of Biological Sciences, Warwick University, Coventry CV4 7AL, UK
Nature 449:1058-62. 2007..Our results suggest a new mechanism for the initiation of eye development...
Chordin affects pronephros development in Xenopus embryos by anteriorizing presomitic mesodermTracy Mitchell
University of Wisconsin Medical School, Department of Biomolecular Chemistry, Madison Wisconsin, USA
Dev Dyn 236:251-61. 2007..Our data support the hypothesis that chordin directs the formation of anterior somites that in turn are necessary for pronephros development...
GDNF expression during Xenopus developmentJun ichi Kyuno
Molecular Physiology, Department of Biological Sciences, Warwick University, Gibbet Hill Road, Coventry CV4 7AL, UK
Gene Expr Patterns 7:313-7. 2007..These results suggest that this X. laevis gene is the orthologue for GDNF...
Comparative genomic and expression analysis of the conserved NTPDase gene family in XenopusKarine Masse
Department of Biological Sciences, Warwick University, Coventry, CV47AL, UK
Genomics 87:366-81. 2006..During development, all NTPDase genes, except for NTPDase8, are expressed and display a distinct specific expression pattern, suggesting potentially different functions of these proteins during embryogenesis of X. laevis...
Distal enhancer elements transcribe intergenic RNA in the IL-10 family gene clusterElizabeth A Jones
Section of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA
J Immunol 175:7437-46. 2005..Hence, we speculate that these novel regulatory elements in the IL-10 family gene locus function via an intermediate regulatory RNA...
Developmental expression of Pod 1 in Xenopus laevisSubreena Simrick
Molecular Physiology, Department of Biological Sciences, Warwick University, Coventry, UK
Int J Dev Biol 49:59-63. 2005..Adult organ analysis shows expression is highest in the rectum and the spleen, with significant expression in the duodenum, heart, kidney, lungs, pancreas, skin, liver and muscle...
Annexin IV (Xanx-4) has a functional role in the formation of pronephric tubulesRachel A Seville
Cell and Molecular Development Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
Development 129:1693-704. 2002..In this study, we demonstrate an in vivo role for annexin IV in the development of the pronephric tubules in Xenopus laevis...
NFAT4 is expressed in primary astrocytes and activated by glutamateElizabeth A Jones
Department of Pharmacology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
J Neurosci Res 72:191-7. 2003..These data suggest that NFAT4 functions as a calcium-responsive transcription factor in astrocytes...
Cloning and characterisation of the immunophilin X-CypA in Xenopus laevisKarine Masse
Molecular Physiology, Department of Biological Sciences, Warwick University, Gibbet Hill Road, Coventry CV4 7AL, UK
Gene Expr Patterns 5:51-60. 2004..Over-expression of X-CypA in embryos, analysed by in situ hybridisation and RT-PCR, leads to an expansion and disorganisation of the neural crest domain...
Xenopus: a prince among models for pronephric kidney developmentElizabeth A Jones
Molecular Physiology, Department of Biological Sciences, Warwick University, Coventry CV4 7AL, UK
J Am Soc Nephrol 16:313-21. 2005..These techniques can be used to help identify the gene networks that control organogenesis of this larval kidney form, which will undoubtedly have applicability to higher vertebrate kidney development...
