Jones A, Buckingham S, Sattelle D. Proteins interacting with nicotinic acetylcholine receptors: expanding functional and therapeutic horizons. Trends Pharmacol Sci. 2010;31:455-62 pubmed publisher
..Mutations giving rise to disease states highlight the importance of these interacting proteins. Here, we consider their potential as future therapeutic targets for treating diseases associated with altered nAChR function. ..
Jones A, Buckingham S, Brown L, Sattelle D. Alternative splicing of the Anopheles gambiae nicotinic acetylcholine receptor, Agamalphabeta9, generates both alpha and beta subunits. Invert Neurosci. 2009;9:77-84 pubmed publisher
..Our findings further characterise a potential target to control the malaria mosquito as well as provide insights into the diversification of nAChRs. ..
Jones A, Sattelle D. Diversity of insect nicotinic acetylcholine receptor subunits. Adv Exp Med Biol. 2010;683:25-43 pubmed
..Species-specific subunit diversification may offer promising targets for future rational design of insecticides that target specific pest insects while sparing beneficial species. ..
Jones A, Sattelle D. The cys-loop ligand-gated ion channel gene superfamily of the red flour beetle, Tribolium castaneum. BMC Genomics. 2007;8:327 pubmed publisher
..These findings on Tribolium castaneum enhance our understanding of cys-loop LGIC functional genomics and provide a useful basis for the development of improved insecticides that target an important agricultural pest...
Jones A, Bera A, Lees K, Sattelle D. The cys-loop ligand-gated ion channel gene superfamily of the parasitoid wasp, Nasonia vitripennis. Heredity (Edinb). 2010;104:247-59 pubmed publisher