Gerhard Jocham

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc A mechanism for value-guided choice based on the excitation-inhibition balance in prefrontal cortex
    Gerhard Jocham
    Oxford Centre for Functional MRI of the Brain, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Nat Neurosci 15:960-1. 2012
  2. doi Dopamine-mediated reinforcement learning signals in the striatum and ventromedial prefrontal cortex underlie value-based choices
    Gerhard Jocham
    Max Planck Institute for Neurological Research, Cognitive Neurology Research Group, D 50931 Cologne, Germany
    J Neurosci 31:1606-13. 2011
  3. pmc Dopamine DRD2 polymorphism alters reversal learning and associated neural activity
    Gerhard Jocham
    Cognitive Neurology Research Group, Max Planck Institute for Neurological Research, D 50931 Cologne, Germany
    J Neurosci 29:3695-704. 2009
  4. pmc Differential modulation of reinforcement learning by D2 dopamine and NMDA glutamate receptor antagonism
    Gerhard Jocham
    Faculty of Economics and Management, Center for Behavioral Brain Sciences, Max Planck Institute for Neurological Research, D 50931 Cologne, Germany
    J Neurosci 34:13151-62. 2014
  5. pmc Adaptive coding of action values in the human rostral cingulate zone
    Gerhard Jocham
    Cognitive Neurology Research Group, Max Planck Institute for Neurological Research, D 50931 Cologne, Germany
    J Neurosci 29:7489-96. 2009
  6. pmc Dissociable contributions of ventromedial prefrontal and posterior parietal cortex to value-guided choice
    Gerhard Jocham
    FMRIB Centre, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom Center for Behavioral Brain Sciences, Otto von Guericke Universitat Magdeburg, Germany Electronic address
    Neuroimage 100:498-506. 2014
  7. ncbi How to perfect a chocolate soufflé and other important problems
    Timothy E J Behrens
    FMRIB Centre, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Neuron 71:203-5. 2011
  8. doi Neuropharmacology of performance monitoring
    Gerhard Jocham
    Max Planck Institute for Neurological Research, Cognitive Neurology Research Group, Gleueler Strasse 50, D 50931 Cologne, Germany
    Neurosci Biobehav Rev 33:48-60. 2009

Detail Information

Publications8

  1. pmc A mechanism for value-guided choice based on the excitation-inhibition balance in prefrontal cortex
    Gerhard Jocham
    Oxford Centre for Functional MRI of the Brain, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Nat Neurosci 15:960-1. 2012
    ..These data provide evidence for a neural competition mechanism in vmPFC that supports value-guided choice...
  2. doi Dopamine-mediated reinforcement learning signals in the striatum and ventromedial prefrontal cortex underlie value-based choices
    Gerhard Jocham
    Max Planck Institute for Neurological Research, Cognitive Neurology Research Group, D 50931 Cologne, Germany
    J Neurosci 31:1606-13. 2011
    ..These findings show that dopamine-dependent mechanisms enhance reinforcement learning signals in the striatum and sharpen representations of associative values in prefrontal cortex that are used to guide reinforcement-based decisions...
  3. pmc Dopamine DRD2 polymorphism alters reversal learning and associated neural activity
    Gerhard Jocham
    Cognitive Neurology Research Group, Max Planck Institute for Neurological Research, D 50931 Cologne, Germany
    J Neurosci 29:3695-704. 2009
    ..This, in turn, was accompanied by impaired recruitment of the ventral striatum and the right lOFC during reversals, which might explain the behavioral differences between the genetic groups...
  4. pmc Differential modulation of reinforcement learning by D2 dopamine and NMDA glutamate receptor antagonism
    Gerhard Jocham
    Faculty of Economics and Management, Center for Behavioral Brain Sciences, Max Planck Institute for Neurological Research, D 50931 Cologne, Germany
    J Neurosci 34:13151-62. 2014
    ..NMDA receptors on the contrary appear to be required only for approach learning because phasic DA increases during positive PEs are NMDA dependent, whereas phasic decreases during negative PEs are not. ..
  5. pmc Adaptive coding of action values in the human rostral cingulate zone
    Gerhard Jocham
    Cognitive Neurology Research Group, Max Planck Institute for Neurological Research, D 50931 Cologne, Germany
    J Neurosci 29:7489-96. 2009
    ..Thus, both the window of trials over which reinforcement information is integrated and adjustment of action values in the RCZ covary with the stochastics of the environment...
  6. pmc Dissociable contributions of ventromedial prefrontal and posterior parietal cortex to value-guided choice
    Gerhard Jocham
    FMRIB Centre, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom Center for Behavioral Brain Sciences, Otto von Guericke Universitat Magdeburg, Germany Electronic address
    Neuroimage 100:498-506. 2014
    ..These data demonstrate that parallel cortical mechanisms may resolve the same choices in differing circumstances, and offer an explanation of the diverse neural signals reported in vmPFC and PPC during value-guided choice. ..
  7. ncbi How to perfect a chocolate soufflé and other important problems
    Timothy E J Behrens
    FMRIB Centre, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Neuron 71:203-5. 2011
    ..A new study reports brain responses consistent with such "hierarchical reinforcement learning."..
  8. doi Neuropharmacology of performance monitoring
    Gerhard Jocham
    Max Planck Institute for Neurological Research, Cognitive Neurology Research Group, Gleueler Strasse 50, D 50931 Cologne, Germany
    Neurosci Biobehav Rev 33:48-60. 2009
    ..Here, we review the evidence for neurotransmitter effects on this function in humans. In this light, we critically discuss currently debated models of performance monitoring and potential alternatives...