M D Jenkinson

Summary

Affiliation: University of Liverpool
Country: UK

Publications

  1. Jenkinson M, Weber D, Haylock B, Mallucci C, Zakaria R, Javadpour M. Atypical meningoma: current management dilemmas and prospective clinical trials. J Neurooncol. 2015;121:1-7 pubmed publisher
    ..This review assesses the evidence for current clinical practice, management dilemmas and the need for prospective clinical trials for atypical meningioma. ..
  2. Jenkinson M, Hayhurst C, Al Jumaily M, Kandasamy J, Clark S, Mallucci C. The role of endoscopic third ventriculostomy in adult patients with hydrocephalus. J Neurosurg. 2009;110:861-6 pubmed publisher
  3. Theodoulou E, Baborie A, Jenkinson M. Low grade glioma in an adult patient with Sotos syndrome. J Clin Neurosci. 2015;22:413-5 pubmed publisher
    ..Sotos syndrome is a rare overgrowth syndrome with an increased risk of tumorigenesis. To our knowledge we report the first case of astrocytoma in an adult patient with Sotos syndrome and describe the clinical course. ..
  4. Jenkinson M, Javadpour M, Haylock B, Young B, Gillard H, Vinten J, et al. The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial. Trials. 2015;16:519 pubmed publisher
    ..The results of this study will be used to inform current neurosurgery and neuro-oncology practice worldwide. ISRCTN71502099 on 19 May 2014. ..
  5. Jenkinson M, du Plessis D, Smith T, Brodbelt A, Joyce K, Walker C. Cellularity and apparent diffusion coefficient in oligodendroglial tumours characterized by genotype. J Neurooncol. 2010;96:385-92 pubmed publisher
    ..This may reflect differences in oligodendroglial tumour biology compared to other gliomas, although the composition of the extracellular matrix may influence ADC more than cellularity. ..
  6. request reprint
    Jenkinson M, Smith T, Brodbelt A, Joyce K, Warnke P, Walker C. Apparent diffusion coefficients in oligodendroglial tumors characterized by genotype. J Magn Reson Imaging. 2007;26:1405-12 pubmed
    ..This preliminary study identified differences in ADC and ATC between oligodendroglial tumor genotypes that may reflect underlying biology. Confirmation in a larger series is warranted. ..
  7. Jenkinson M, Waqar M, Farah J, Farrell M, Barbagallo G, McManus R, et al. Early adjuvant radiotherapy in the treatment of atypical meningioma. J Clin Neurosci. 2016;28:87-92 pubmed publisher
    ..059, p=0.808). Although extent of resection emerged as an important prognostic variable, early adjuvant radiotherapy did not influence outcome following GTR of atypical meningiomas. Prospective randomized controlled trials are planned. ..
  8. Jenkinson M, Smith T, Haylock B, Husband D, Shenoy A, Vinjamuri S, et al. Phase II trial of intratumoral BCNU injection and radiotherapy on untreated adult malignant glioma. J Neurooncol. 2010;99:103-13 pubmed publisher
    ..The imaging data forms a biological basis for understanding the effects of high dose BCNU delivered intratumorally by SFP, and suggests early effects on tumour vasculature and metabolism. ..
  9. Islim A, McKeever S, Kusu Orkar T, Jenkinson M. The role of prophylactic antiepileptic drugs for seizure prophylaxis in meningioma surgery: A systematic review. J Clin Neurosci. 2017;43:47-53 pubmed publisher
    ..However, limitations of a systematic review should be considered on interpretation. High quality prospective randomised controlled trials are required to definitively answer this important clinical question. ..

More Information

Publications10

  1. Leather T, Jenkinson M, Das K, Poptani H. Magnetic Resonance Spectroscopy for Detection of 2-Hydroxyglutarate as a Biomarker for IDH Mutation in Gliomas. Metabolites. 2017;7: pubmed publisher
    ..In this review, we describe the recent efforts in developing MRS methods for detection and quantification of 2-HG in vivo and provide an assessment of the role of the 2-HG in gliomagenesis and patient prognosis. ..